Search Results (2)

Background/Objectives: Precocious puberty in girls currently appears to be one of the main problems in pediatric endocrine gynecology. Early onset of menstruation (EOM) means that the age at which the first menstruation occurs is lower than the average/median for the population, which ranges from 12 to 13 years and depends primarily on ethnic origin. Depending on age and severity of symptoms, these disorders negatively affect girls’ quality of life in many areas, including school life, family relationships, and everyday life. Methods: This article provides a scoping review summarizing scientific evidence from human studies on the association between substances derived from green tea (flavanols) and soy (isoflavones) and precocious puberty in girls. Results: Despite the relatively small number of girls enrolled in the studies, available scientific evidence from randomized controlled trials (RCTs) suggests that polyphenols from decaffeinated green tea (DGTP) may contribute to lowering the age of first menstruation in girls living with obesity. The effect of soy isoflavones or soy in the context of premature menstruation in girls is unclear. Most studies report that it may have no effect on the age of first menstruation, while individual studies suggest that very early exposure to soy (< 4 months of age) may result in earlier puberty, and others suggest that higher consumption of soy isoflavones delays this process. Conclusions: Further well-designed intervention studies in humans are needed to better understand the endocrine and metabolic relationships regarding the role and importance of specific polyphenols in the pathogenic mechanisms of the development and treatment of precocious puberty in girls. Full article

Tea, derived from the leaves of Camellia sinensis is globally recognized for its cultural significance and potential health benefits. While extensively studied in adults, the effects of tea consumption in children remain underexplored. This review examines tea′s bioactive compounds, such as catechins, flavonoids, and L-theanine, and their cognitive, cardiovascular, metabolic, oral, and hepatoprotective benefits with a critical overview of its consumption in pediatric populations. Additionally, the review addresses potential risks, including caffeine-related effects, interference with iron absorption, and hepatotoxicity at high doses. Emerging evidence suggests that tea is a beneficial alternative to sugar-sweetened beverages for children when consumed in moderation. However, caution is warranted regarding caffeine content and the balance of bioactive components. This analysis underscores the importance of further research to establish safe and effective guidelines for tea consumption in children. Full article