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12 Results Found

  • Article
  • Open Access
10 Citations
5,246 Views
11 Pages

Pathogenicity Islands Distribution in Non-O157 Shiga Toxin-Producing Escherichia coli (STEC)

  • Jimena Soledad Cadona,
  • Ana Victoria Bustamante,
  • Juliana González and
  • Andrea Mariel Sanso

10 February 2018

Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens associated with outbreaks and hemolytic-uremic syndrome. Cattle and meat foods are the main reservoir and infection source, respectively. Pathogenicity islands (PAIs) play an impor...

  • Article
  • Open Access
7 Citations
6,003 Views
18 Pages

Neem Leaf Extract Exhibits Anti-Aging and Antioxidant Effects from Yeast to Human Cells

  • Jinye Dang,
  • Gongrui Zhang,
  • Jingjing Li,
  • Libo He,
  • Yi Ding,
  • Jiaxiu Cai,
  • Guohua Cheng,
  • Yuhui Yang,
  • Zhiyi Liu and
  • Ke Liu
  • + 2 authors

16 May 2024

Neem leaves have long been used in traditional medicine for promoting longevity. However, the precise mechanisms underlying their anti-aging effects remain elusive. In this study, we investigated the impact of neem leaf extract (NLE) extracted from a...

  • Article
  • Open Access
34 Citations
5,610 Views
15 Pages

Virulence Characteristics and Antimicrobial Resistance Profiles of Shiga Toxin-Producing Escherichia coli Isolates from Humans in South Africa: 2006–2013

  • Musafiri Karama,
  • Beniamino T. Cenci-Goga,
  • Mogaugedi Malahlela,
  • Anthony M. Smith,
  • Karen H. Keddy,
  • Saeed El-Ashram,
  • Lawan M. Kabiru and
  • Alan Kalake

19 July 2019

Shiga toxin-producing Escherichia coli (STEC) isolates (N = 38) that were incriminated in human disease from 2006 to 2013 in South Africa were characterized by serotype, virulence-associated genes, antimicrobial resistance and pulsed-field gel electr...

  • Article
  • Open Access
2 Citations
2,232 Views
24 Pages

Enhancing Antitumor Efficacy of MUC1 mRNA Nano-Vaccine by CTLA-4 siRNA-Mediated Immune Checkpoint Modulation in Triple Negative Breast Cancer Mice Model

  • Amir Monfaredan,
  • Sena Şen,
  • Nahideh Karimian Fathi,
  • Didem Taştekin,
  • Alaviyehsadat Hosseininasab,
  • Hamza Uğur Bozbey and
  • Oral Öncül

30 August 2025

Immunotherapy, particularly approaches that combine tumor-specific vaccines with immune checkpoint modulation, represents a promising strategy for overcoming tumor immune evasion. While most mRNA-based cancer vaccines focus solely on antigen delivery...

  • Article
  • Open Access
9 Citations
2,938 Views
12 Pages

Impact of Allelic Variation in Maturity Genes E1E4 on Soybean Adaptation to Central and West Siberian Regions of Russia

  • Roman Perfil’ev,
  • Andrey Shcherban,
  • Dmitriy Potapov,
  • Konstantin Maksimenko,
  • Sergey Kiryukhin,
  • Sergey Gurinovich,
  • Veronika Panarina,
  • Revmira Polyudina and
  • Elena Salina

Four maturity genes, namely, E1, E2, E3 and E4, have been found to play major roles in controlling the flowering and maturity time of soybean. Which genotypes of E1E4 genes provide effective adaptation to the varied conditions of Russia are un...

  • Article
  • Open Access
11 Citations
3,040 Views
14 Pages

12 August 2023

Hybrid strains Escherichia coli acquires genetic characteristics from multiple pathotypes and is speculated to be more virulent; however, understanding their pathogenicity is elusive. Here, we performed genome-based characterization of the hybrid of...

  • Article
  • Open Access
21 Citations
8,410 Views
24 Pages

23 October 2013

Mycotoxin mixtures are associated with Shiga toxin-producing Escherichia coli (STEC) infections in mature cattle. STEC are considered commensal bacteria in mature cattle suggesting that mycotoxins provide a mechanism that converts this bacterium to a...

  • Article
  • Open Access
212 Views
14 Pages

Whole-Genome Sequence Analysis of Shiga Toxin-Producing Escherichia coli Isolated from Livestock Animals in Ghana

  • Yusuke Ota,
  • Samiratu Mahazu,
  • Ivy Brago Amanor,
  • Frederick Ofosu Appiah,
  • Jennifer Amedior,
  • Emmanuel Darko,
  • Mitsunori Yoshida,
  • Masato Suzuki,
  • Yoshihiko Hoshino and
  • Ryoichi Saito
  • + 2 authors

Shiga toxin-producing Escherichia coli (STEC) is a zoonotic pathogen of public health concern, requiring a One Health approach to clarify its transmission and distribution. However, its prevalence and genomic characteristics in livestock and companio...

  • Review
  • Open Access
32 Citations
13,890 Views
26 Pages

Harmonious synthesis and distribution of melanin in the skin contribute to the expression of beauty and the maintenance of health. When skin pigmentary disorders occur because of internal or external factors or, when there is a need to artificially i...

  • Article
  • Open Access
24 Citations
4,198 Views
20 Pages

15 September 2019

The white-back planthopper (WBPH), Sogatella furcifera, is a major rice pest in China and in some other rice-growing countries of Asia. The extensive use of pesticides has resulted in severe resistance of S. furcifera to variety of chemical insectici...

  • Article
  • Open Access
753 Views
30 Pages

29 November 2025

Breast cancer is highly heterogeneous, with multiple subtypes that differ in molecular and clinical characteristics. It remains the most common cancer among women worldwide. We conducted a hypothesis-generating study using a bioinformatics approach i...

  • Article
  • Open Access
2 Citations
2,867 Views
15 Pages

Functional Analysis of CPSF30 in Nilaparvata lugens Using RNA Interference Reveals Its Essential Role in Development and Survival

  • Shengli Jing,
  • Jing Yang,
  • Yali Liu,
  • Feifei Wang,
  • Fang Zheng,
  • Aobo Ren,
  • Bingbing Yu,
  • Yue Zhao,
  • Bing Jia and
  • Jingang Xu
  • + 3 authors

3 November 2024

The brown planthopper (Nilaparvata lugens) is a major pest threatening global rice production, significantly reducing yields annually. As N. lugens increasingly develops resistance to conventional control methods, such as chemical pesticides, there i...