Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (24,292)

Search Parameters:
Keywords = imaging algorithm

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
16 pages, 1554 KB  
Review
Explainable and Trustworthy Artificial Intelligence in Cardiology: A Narrative Review of Clinical Applications, Operational Integration, and Future Directions
by Mateusz Lucki, Ewa Lucka, Jacek Żak, Przemysław Mitkowski and Maciej Lesiak
J. Clin. Med. 2026, 15(13), 4885; https://doi.org/10.3390/jcm15134885 (registering DOI) - 23 Jun 2026
Abstract
Background/Objectives: Artificial intelligence (AI) is increasingly transforming cardiology through advanced analytical tools capable of identifying complex patterns across cardiovascular imaging, electrophysiology, and clinical datasets. Machine learning (ML) and deep learning (DL) algorithms are being integrated into echocardiography, cardiac computed tomography (CT), cardiac magnetic [...] Read more.
Background/Objectives: Artificial intelligence (AI) is increasingly transforming cardiology through advanced analytical tools capable of identifying complex patterns across cardiovascular imaging, electrophysiology, and clinical datasets. Machine learning (ML) and deep learning (DL) algorithms are being integrated into echocardiography, cardiac computed tomography (CT), cardiac magnetic resonance imaging (MRI), and electrocardiography (ECG), enabling earlier diagnosis and more personalized cardiovascular care. This narrative review summarizes current clinical and organizational applications of AI in cardiology and discusses emerging concepts related to explainable and trustworthy AI. Methods: A narrative review was conducted according to SANRA recommendations using the PubMed, MEDLINE, Web of Science, and Scopus databases, including peer-reviewed publications from 2015 to 2026 addressing clinical, organizational, and ethical applications of AI in cardiology, with particular emphasis on cardiovascular imaging, electrocardiography, heart failure, digital health, and explainable AI frameworks. Results: Substantial evidence demonstrates that AI-based tools can achieve expert-level performance in cardiovascular imaging interpretation, automated electrocardiographic analysis, and clinical risk prediction. Across multiple cardiovascular settings, AI has been associated with improved diagnostic accuracy, enhanced workflow efficiency, and earlier detection of cardiovascular disease. Predictive models support risk stratification in heart failure and ischemic heart disease, while chatbots and digital health platforms may facilitate patient engagement, remote monitoring, and continuity of care. Despite these advances, important challenges remain, including algorithmic bias, limited transparency, insufficient external validation, data heterogeneity, and barriers to routine clinical implementation. Emerging explainable AI approaches may improve model interpretability, clinician confidence, and the safe adoption of AI-driven decision support systems. Conclusions: Artificial intelligence is rapidly evolving from a research-oriented technology into a clinically relevant component of cardiovascular care. Current evidence indicates that AI can enhance diagnostic performance, improve risk prediction, streamline clinical workflows, and facilitate more personalized management across multiple cardiovascular domains. However, the successful translation of AI into routine practice will depend on robust external validation, transparent decision-making mechanisms, regulatory oversight, and clinician acceptance. The development of explainable and trustworthy AI frameworks represents a critical step toward the safe, ethical, and sustainable integration of AI into modern cardiology. Full article
Show Figures

Figure 1

36 pages, 3020 KB  
Article
An Enhanced Equilibrium Optimizer Based on Rural Tourism Inspiration Strategy for Global Optimization and Engineering Applications
by Zhiwang Xu, Hui Xie and Chengpeng Li
Systems 2026, 14(7), 728; https://doi.org/10.3390/systems14070728 (registering DOI) - 23 Jun 2026
Abstract
As the complexity, scale, and nonlinearity of modern engineering optimization problems continue to increase, traditional optimization algorithms face significant challenges in achieving high solution accuracy, fast convergence, and robust performance. To address these issues, this paper proposes a Rural Tourism Migration-based Improved Equilibrium [...] Read more.
As the complexity, scale, and nonlinearity of modern engineering optimization problems continue to increase, traditional optimization algorithms face significant challenges in achieving high solution accuracy, fast convergence, and robust performance. To address these issues, this paper proposes a Rural Tourism Migration-based Improved Equilibrium Optimizer (RTM-IEO), aiming to enhance the global search capability and adaptive balance between exploration and exploitation. Specifically, an adaptive lens imaging opposition-based learning strategy is introduced to effectively expand the search space and maintain population diversity. A dynamic elite-guided elimination mechanism is designed to strengthen exploitation capability and accelerate convergence by reconstructing inferior individuals using high-quality solutions. In addition, a multi-stage rural tourism migration strategy is developed to dynamically regulate the search behavior across different optimization phases, enabling a more flexible and efficient search process. The effectiveness of the proposed algorithm is comprehensively validated on the CEC2021 and CEC2022 benchmark suites, where RTM-IEO demonstrates superior performance in terms of convergence accuracy, convergence speed, and robustness compared with several representative state-of-the-art algorithms. The statistical superiority of the proposed method is further confirmed through Friedman mean ranking and Wilcoxon rank-sum tests. To further evaluate its practical applicability, RTM-IEO is applied to the sustainable economic dispatch problem of a microgrid integrating renewable energy sources, including wind power and photovoltaic generation, along with energy storage systems and controllable units. The optimization objective simultaneously considers economic cost minimization and sustainable operation requirements, such as improving renewable energy utilization and reducing dependence on fossil-fuel-based generation. Experimental results indicate that the proposed method achieves a significant reduction in daily operating cost (exceeding 52% compared with benchmark algorithms), while effectively promoting low-carbon energy utilization and enhancing overall system sustainability. Overall, the proposed RTM-IEO provides an efficient and reliable optimization framework for addressing complex global optimization problems, particularly in scenarios requiring a coordinated balance between economic performance and sustainable development. Full article
29 pages, 1889 KB  
Article
Child Presence Detection Algorithm in School Buses Based on Infrared Array
by Yongjun Liu, Gaosong Li, Xuepeng Yuan and Shuai Zhang
Sensors 2026, 26(13), 3982; https://doi.org/10.3390/s26133982 (registering DOI) - 23 Jun 2026
Abstract
School buses serve as the primary mode of transportation for children traveling to and from school, and their safety measures represent a critical safeguard for children’s lives. Nevertheless, incidents in which children are left unattended on school buses—due to inadequate supervision or the [...] Read more.
School buses serve as the primary mode of transportation for children traveling to and from school, and their safety measures represent a critical safeguard for children’s lives. Nevertheless, incidents in which children are left unattended on school buses—due to inadequate supervision or the children’s own actions—occur with notable frequency and can lead to fatal outcomes. To mitigate or prevent such tragedies, this paper proposes an in-vehicle thermal imaging solution based on infrared array sensors, integrated with a dedicated algorithm to detect whether a child has been left behind in the school bus. The system collects background temperature, presence temperature, and real-time temperature data inside the bus using infrared array sensors. By comparing the real-time temperature difference against a predefined presence temperature difference threshold, the algorithm determines whether a child is present under the current thermal conditions. It then verifies whether the number of positive detections within a specified temperature range meets a preset presence count threshold, thereby reaching a final decision regarding child presence. Experiments identified optimal parameters: a temperature range of 26–33 °C, a double-difference threshold (ε = 1), and a presence count threshold (P = 4). Random testing demonstrated that the proposed technical solution and algorithm achieve an overall detection success rate of 92.5%. This study develops a low-cost, easily deployable, non-contact thermal imaging method capable of identifying forgotten children on school buses with satisfactory accuracy. By detecting retention before harm occurs, the approach enhances the safety of children traveling by school bus. Full article
(This article belongs to the Section Sensing and Imaging)
28 pages, 2694 KB  
Systematic Review
Human Digital Twins in Personalized Medicine: A Systematic Review and Bibliometric–Thematic Synthesis of Methodological Advances and Clinical Applications
by Carlotta Fontana and Sina Zinatlou Ajabshir
Computation 2026, 14(7), 143; https://doi.org/10.3390/computation14070143 (registering DOI) - 23 Jun 2026
Abstract
Human digital twins (HDTs) are patient-specific computational models that combine medical imaging, physiological measurements and predictive algorithms. They are moving from an exciting concept to a realistic clinical opportunity. The key question is no longer whether HDTs can be built. The key question [...] Read more.
Human digital twins (HDTs) are patient-specific computational models that combine medical imaging, physiological measurements and predictive algorithms. They are moving from an exciting concept to a realistic clinical opportunity. The key question is no longer whether HDTs can be built. The key question is which methods are mature enough to support clinical decisions and what is still missing for routine use. This systematic review maps the methodological landscape of HDTs and highlights practical bottlenecks that limit clinical translation. A PRISMA 2020 guided search of PubMed, Scopus, IEEE Xplore, and the Cochrane Library, covering publications from 2016 to 2026, identified 151 eligible studies. Bibliometric mapping and thematic synthesis were used to characterize research clusters, computational paradigms, and collaboration patterns. Three dominant application streams were identified: cardiovascular HDTs for hemodynamic simulation and procedural planning, musculoskeletal HDTs for biomechanics-driven orthopedic innovation, and neurological HDTs integrating neuroimaging with computational neuroscience. Across domains, the strongest technical trend is the rise in hybrid pipelines that combine physics-based simulation, including finite element and computational fluid dynamics models, with machine learning for segmentation, parameter identification, reduced-order modeling, and faster inference. However, reporting of verification, validation, uncertainty quantification, and explicit context of use remains uneven and prospective clinical evidence is still limited. Overall, the literature shows rapid progress toward clinically credible HDTs, while highlighting the need for scalable computation, standardized credibility pipelines, and workflow-integrated platforms to support safe and reproducible clinical adoption. Full article
Show Figures

Graphical abstract

27 pages, 7020 KB  
Article
MSA-YOLO: An Optimized UAV Object Detection Algorithm for Low-Visibility Maritime
by Longcheng Huang, Mengguang Liao, Shaoning Li, Chuanguang Zhu and Sichun Long
Remote Sens. 2026, 18(13), 2065; https://doi.org/10.3390/rs18132065 (registering DOI) - 23 Jun 2026
Abstract
Maritime search and rescue is an important component of emergency response frameworks and primarily relies on Unmanned Aerial Vehicles (UAVs) for maritime object detection. However, maritime accidents frequently occur in low-visibility environments, such as foggy or low-light conditions, which lead to low contrast, [...] Read more.
Maritime search and rescue is an important component of emergency response frameworks and primarily relies on Unmanned Aerial Vehicles (UAVs) for maritime object detection. However, maritime accidents frequently occur in low-visibility environments, such as foggy or low-light conditions, which lead to low contrast, blurred object boundaries, and degraded texture representations. Most existing maritime object detection algorithms are developed for natural light scenes, and their performance deteriorates markedly when deployed directly in low-visibility environments, primarily due to reduced image quality that hinders feature extraction and semantic information aggregation. Although several studies incorporate image enhancement techniques prior to detection to improve image quality, these approaches often introduce significant additional computational overhead, limiting their practical deployment on UAV platforms. To tackle these challenges, this paper proposes a lightweight model built upon a recent YOLO framework, termed Multi-Scale Adaptive YOLO (MSA-YOLO), for maritime detection using UAVs in low-visibility environments. The proposed model systematically optimizes the backbone, neck, and detection head networks. Specifically, an improved StarNet backbone is designed by integrating Efficient Channel Attention (ECA) mechanisms and multi-scale convolutional kernels, which strengthen feature extraction capability while maintaining low computational overhead. In the neck network, a high-frequency enhanced residual block branch is inserted into the C3k2 module to capture richer detailed information, while depthwise separable convolution is utilized to further reduce computational cost. Moreover, a non-parametric attention module is incorporated into the detection head to adaptively optimize features in the classification and regression branches. Finally, a joint loss function that combines bounding box regression, classification, and distribution focal losses is utilized to improve detection accuracy and training stability. Experimental results on the constructed AFO, Zhoushan Island, and Shandong Province datasets demonstrate that, relative to YOLOv11-s, MSA-YOLO reduces model parameters and FLOPs by 52.07% and 41.36%, respectively, while achieving improvements of 1.11% and 1.33% in mAP@0.5:0.95 and mAP@0.5. These results indicate that the proposed method effectively balances computational efficiency and detection accuracy, rendering it suitable for practical maritime search and rescue applications in low-visibility environments. Full article
Show Figures

Figure 1

37 pages, 6098 KB  
Review
AI-Augmented Systematic Review of Remote Sensing and Predictive Modelling for Mycotoxin Risk Monitoring in Cereal Crops Across Central and Balkan Europe
by László Radócz, Attila Nagy, Nikolett Szőllősi, Nikolett Éva Kiss, Andrea Szabó, János Tamás, Nxumalo Gift Siphiwe and László Radócz
Remote Sens. 2026, 18(13), 2063; https://doi.org/10.3390/rs18132063 (registering DOI) - 23 Jun 2026
Abstract
Mycotoxin contamination of cereal crops poses escalating food safety risks across the Central and Balkan European (CBE) corridor under climate change, yet no PRISMA 2020-compliant synthesis of remote sensing (RS) and machine learning (ML) evidence for this region exists. We conducted an AI-augmented [...] Read more.
Mycotoxin contamination of cereal crops poses escalating food safety risks across the Central and Balkan European (CBE) corridor under climate change, yet no PRISMA 2020-compliant synthesis of remote sensing (RS) and machine learning (ML) evidence for this region exists. We conducted an AI-augmented systematic review applying a four-stage automated pipeline—PICO domain scoring, SBERT semantic deduplication, and Thompson-sampling reinforcement learning—to 36,038 corpus records (2010–2025), yielding 156 included studies (inter-rater κ = 0.81 (95% CI: 0.74–0.88)). Logistic growth modelling identified a 56-fold corpus expansion with inflection at t0 = 2024.8 (R2 = 0.981). Satellite multispectral imaging dominated the literature (91.7% of studies); random forest and gradient boosting models achieved R2 = 0.74–0.80 for aflatoxin B1 and deoxynivalenol prediction in CBE maize and wheat when integrating vegetation indices, land surface temperature, and precipitation covariates. Deep learning surpassed classical ML in annual study count from 2021, reaching ~60% relative share by 2025, though the performance advantage narrows at field scale relative to laboratory hyperspectral benchmarks (98–99% accuracy). A five-percentage-point CBE–global performance gap is largely consistent with differences in sample size and multi-toxin design scope rather than algorithmic access. The country × mycotoxin gap matrix identifies zero eligible studies for four CBE nations and for T-2/HT-2 toxins across the Balkan states. Climate-driven satellite mycotoxin prediction emerges as the field’s active research frontier. Full article
(This article belongs to the Special Issue Plant Disease Detection and Recognition Using Remotely Sensed Data)
Show Figures

Figure 1

25 pages, 68864 KB  
Article
A Morpho-Phase Feature-Based Method for Geometric Error Mitigation in InSAR Image Matching
by Yanming Chen, Fan Zhang, Yanfang Liu, Fei Ma and Bingnan Wang
Remote Sens. 2026, 18(13), 2060; https://doi.org/10.3390/rs18132060 (registering DOI) - 23 Jun 2026
Abstract
Interferometric Synthetic Aperture Radar (InSAR) is a promising payload for Unmanned Aerial Vehicle (UAV) scene matching navigation due to the rich textures in interferogram images compared to SAR intensity images. However, geometric parameter estimation errors during reference interferogram image generation cause significant textural [...] Read more.
Interferometric Synthetic Aperture Radar (InSAR) is a promising payload for Unmanned Aerial Vehicle (UAV) scene matching navigation due to the rich textures in interferogram images compared to SAR intensity images. However, geometric parameter estimation errors during reference interferogram image generation cause significant textural discrepancies with real-time data. Compounded by inherent non-local similarity of InSAR images, these issues render conventional matching algorithms ineffective, degrading navigation accuracy. To address these challenges, this paper proposes a Morpho-Phase feature-based InSAR image matching method to mitigate the impact of parameter errors. Firstly, a Phase-Robust Keypoint (PRK) detection method is proposed, which overcomes the impact of parameter errors on keypoint detection by introducing a compensated phase and extracting phase extrema. Secondly, a Hierarchical Morphological-Phase Descriptor (HMPD) is constructed to resolve the feature ambiguity caused by the non-local similarity of interferograms by combining morphological features with phase statistics. Experimental results based on real-world InSAR data demonstrate that the proposed matching method effectively mitigates the impact of parameter errors on InSAR image matching, enhances navigation positioning accuracy, and provides stable, high-precision positioning capabilities in practical scene matching navigation tasks. Full article
Show Figures

Figure 1

15 pages, 1609 KB  
Article
Hybrid Metaheuristic Feature Selection for Breast Cancer Detection in Digital Mammography: A Feasibility Study with Nested Validation, Benchmarking, and External Stress Testing
by Bandar S. Alshreef and Yousif A. Kariri
J. Clin. Med. 2026, 15(12), 4846; https://doi.org/10.3390/jcm15124846 (registering DOI) - 22 Jun 2026
Abstract
Background/Objectives: The “small-n-large-p” dilemma in mammography artificial intelligence (AI)—where the number of candidate imaging features far exceeds the number of labeled cases—commonly results in model overfitting, unstable feature selection, and poor generalization across clinical settings. This study aims to reassess the internal performance [...] Read more.
Background/Objectives: The “small-n-large-p” dilemma in mammography artificial intelligence (AI)—where the number of candidate imaging features far exceeds the number of labeled cases—commonly results in model overfitting, unstable feature selection, and poor generalization across clinical settings. This study aims to reassess the internal performance of the HiTopology-GOA-CSA (Grasshopper Optimization Algorithm–Crow Search Algorithm) feature-selection framework for mammography using a larger real Curated Breast Imaging Subset of Digital Database for Screening Mammography (CBIS-DDSM) cohort and a stricter leakage-aware evaluation strategy. Methods: In this retrospective computational study using public anonymized datasets, an expanded internal cohort of 98 CBIS-DDSM mass cases (49 benign, 49 malignant) was assembled from digital imaging and communications in medicine (DICOM) region of interest (ROI) series. A total of 1074 features were extracted per case, including 88 handcrafted radiomic descriptors and 986 EfficientNet-B5 deep features. HiTopology-GOA-CSA selected 102 features, corresponding to 91% feature reduction. Two internal evaluation modes were compared: Mode A, which matched the original pilot methodology by performing feature selection once on the full cohort before cross-validation, and Mode B, which used strict nested feature selection within training folds. Performance was assessed with 5-fold stratified cross-validation using a multilayer perceptron (MLP) classifier. Results: On the expanded cohort, Mode A achieved an area under the receiver operating characteristic curve (AUC) of 0.726 (95% CI: 0.594–0.858), sensitivity of 0.658, specificity of 0.651, and F1-score of 0.644. Under the stricter nested evaluation, Mode B achieved AUC of 0.683 (95% CI: 0.549–0.817), sensitivity of 0.598, specificity of 0.631, and F1-score of 0.595. Mean pairwise Jaccard similarity across nested folds was 0.604, indicating moderate feature stability. Benchmark comparisons showed that the proposed method was competitive but did not outperform standard baselines; LASSO logistic regression achieved the highest AUC of 0.739, while the proposed HiTopology-GOA-CSA + MLP achieved an AUC of 0.683. Real external validation on the locked VinDr-Mammo subset (n = 25) remained near-random (AUC of 0.500 [95% CI: 0.304–0.696]), with complete prediction collapse (sensitivity of 1.000, specificity of 0.000). Conclusions: The framework demonstrated feasibility for structured feature selection and stress testing in a small-cohort mammography AI setting; however, external validation revealed near-random discrimination and prediction collapse, indicating limited generalizability. These findings emphasize the need for benchmark comparisons, transparent uncertainty reporting, patient-level validation, and larger multicenter datasets before clinical translation. Full article
(This article belongs to the Special Issue Clinical Advances in Cancer Imaging)
17 pages, 2302 KB  
Review
Early Rectal Cancer: Diagnostic Challenges and the Role of Endoscopic Intermuscular Dissection Within the Therapeutic Algorithm
by Rossella Maresca, Giulio Calabrese, Franziska Deutschbein, Valentina Blasi, Tommaso Schepis, Daniele Salvi, Silvia Pecere, Paola Cesaro, Cristiano Spada, Sandro Sferrazza and Federico Barbaro
Diagnostics 2026, 16(12), 1936; https://doi.org/10.3390/diagnostics16121936 (registering DOI) - 22 Jun 2026
Abstract
Early rectal cancer represents a challenging setting in which accurate locoregional staging is essential to guide appropriate treatment. Current diagnostic strategies primarily include magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS). However, both modalities show significant limitations in early-stage disease, particularly in T [...] Read more.
Early rectal cancer represents a challenging setting in which accurate locoregional staging is essential to guide appropriate treatment. Current diagnostic strategies primarily include magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS). However, both modalities show significant limitations in early-stage disease, particularly in T staging. This diagnostic gap impacts therapeutic decision-making, particularly in patients with lesions suggestive of deep submucosal invasion. In these cases, endoscopic submucosal dissection (ESD) may be insufficient to achieve adequate vertical negative margins, whereas radical surgery is associated with considerable morbidity and potential impairment of quality of life. In this gray zone, endoscopic intermuscular dissection (EID) has recently emerged as a novel therapeutic approach designed to overcome the limitations of standard endoscopic resection. By enabling dissection within the deeper intermuscular plane, it can achieve curative resections while preserving rectal wall integrity. This narrative review aims to explore the current diagnostic gaps in early rectal cancer and to define the potential role of EID within the current therapeutic algorithm. Full article
(This article belongs to the Special Issue Advances in Gastrointestinal Endoscopy: From Diagnosis to Therapy)
Show Figures

Figure 1

22 pages, 3544 KB  
Article
Radiographic Angle-Based Machine Learning Models for the Diagnosis of Pes Planus and Pes Cavus: A Large-Scale Study Using Weight-Bearing Lateral Foot Radiographs
by Rabia Taşdemir, Mustafa Işık, Ahmet Hakan İnce, Ebru Sena Poyraz, Şule Baysal, Ramazan Parıldar and Nevzat Gönder
Diagnostics 2026, 16(12), 1929; https://doi.org/10.3390/diagnostics16121929 (registering DOI) - 22 Jun 2026
Abstract
Background/Objectives: Pes planus and pes cavus are common foot deformities, which may lead to pain, functional limitations, and impairment of foot biomechanics. While calcaneal pitch, talar declination, and Meary angles, commonly used in diagnosis, provide objective information, their lack of a gold [...] Read more.
Background/Objectives: Pes planus and pes cavus are common foot deformities, which may lead to pain, functional limitations, and impairment of foot biomechanics. While calcaneal pitch, talar declination, and Meary angles, commonly used in diagnosis, provide objective information, their lack of a gold standard and the observer’s dependence on manual measurements limit their reliability. Therefore, in this study, these angles obtained from weight-bearing lateral foot radiographs were evaluated according to literature references, and the aim was to determine the model that provides the most accurate prediction in the diagnosis of pes planus using machine learning algorithms. It should be emphasized that, because the diagnostic labels were derived from literature-based thresholds of these same angles, the machine-learning task addressed here is the automated reproduction and standardization of expert, angle-threshold-based classification, rather than an independent clinical diagnosis from raw images. Methods: This retrospective study was conducted using weight-bearing lateral foot radiographs of 697 male patients obtained from the archives of public hospitals in Gaziantep. Calcaneal pitch, Meary angle, and talar declination angles were evaluated in both feet, and the data were labeled as normal, pes planus, and pes cavus. The dataset, consisting of a total of 1394 feet, was divided into training and test groups and analyzed using Random Forest, XGBoost, Logistic Regression, Support Vector Machine (SVM), and K-Nearest Neighbors (KNN) algorithms; the diagnostic performance of the models was compared using measures such as accuracy, F1 score, sensitivity, and specificity. Results: A total of 1394 feet from 697 male patients (mean age 24.8 ± 5.57 years) were analyzed using five machine learning algorithms with calcaneal pitch angle (CPA), Meary angle (MA), and talar declination angle (TDA) as reference labels. Ensemble-based methods showed superior performance, with XGBoost achieving perfect classification (Accuracy = 1.000) under all three labels for the left foot and 0.996–1.000 for the right foot, while Random Forest reached 0.986–1.000 across all experiments. Logistic Regression and SVM yielded moderate accuracies (0.905–0.973), whereas KNN consistently performed the weakest (0.905–0.964), particularly in the pes cavus subgroup. The near-perfect accuracy obtained when the labeling angle was itself included among the predictors reflects, at least in part, the algebraic reconstruction of the threshold rule from a same-source variable rather than genuine diagnostic generalization; results should therefore be interpreted with this in mind. Conclusions: This study demonstrates that machine learning, particularly ensemble methods such as XGBoost and Random Forest, provides high accuracy and consistency in diagnosing foot arch deformities based on radiographic angle measurements. Traditional models, such as Logistic Regression, still hold value in terms of clinical interpretability despite their lower performance. The findings suggest that machine learning-based approaches can offer objective, rapid, and reliable decision support tools for diagnosing pes planus and pes cavus, but external validation studies are necessary for clinical generalizability. Full article
Show Figures

Figure 1

16 pages, 285 KB  
Review
Artificial Intelligence and the Evolving Paradigm of Lung Cancer Management
by Russell Seth Martins, Yousif Hanna and Andrea L. Axtell
Cancers 2026, 18(12), 2012; https://doi.org/10.3390/cancers18122012 (registering DOI) - 22 Jun 2026
Abstract
Lung cancer remains the leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis, biological heterogeneity, and persistent challenges in staging and treatment selection. This narrative review summarizes current and emerging applications of AI across lung cancer screening and early detection, imaging-based [...] Read more.
Lung cancer remains the leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis, biological heterogeneity, and persistent challenges in staging and treatment selection. This narrative review summarizes current and emerging applications of AI across lung cancer screening and early detection, imaging-based staging and prognostication, tissue and liquid biopsy-based tumor characterization, treatment planning, surgical and intraoperative guidance, and drug discovery. In imaging, deep learning models have demonstrated high performance in pulmonary nodule detection, risk stratification, and prediction of molecular alterations, while also showing promise in improving screening efficiency and reducing interpretive variability. In pathology and liquid biopsy domains, AI enables prediction of driver mutations, immunotherapy response, and survival outcomes directly from histopathology slides, circulating tumor DNA, and other blood-based biomarkers, facilitating minimally invasive precision oncology approaches. In treatment planning and delivery, AI systems are being developed to support clinical decision-making, surgical planning (through advanced image segmentation and delineation of operative anatomy), and intraoperative navigation through robotic and computer vision-enabled platforms. Despite these advances, significant barriers remain, including limited real-world validation, algorithmic biases, workflow integration issues, and unresolved ethical and legal concerns. Future progress will depend on the development of transparent, clinically validated, and generalizable AI systems that augment rather than replace the expertise of clinical providers and healthcare teams. Active engagement from pulmonologists, oncologists, radiologists, and thoracic surgeons will be essential in guiding safe implementation and ensuring that AI-driven innovations translate into meaningful improvements in patient outcomes. Full article
(This article belongs to the Section Methods and Technologies Development)
18 pages, 35862 KB  
Article
Enhanced Text-Driven Directional Editing for Marine Dynamic Data Generation
by Zhenfeng Xue, Jiahao Zhang, Chunan Yu, Ying Zang, Zhuo Chen and Zhonghua Miao
J. Mar. Sci. Eng. 2026, 14(12), 1139; https://doi.org/10.3390/jmse14121139 (registering DOI) - 22 Jun 2026
Viewed by 45
Abstract
The generation of high-quality maritime samples is gradually becoming a key and challenging issue, due to the data thirst for training maritime intelligent models. However, existing methods mainly focus on static sample generation, which cannot meet the requirements of algorithms for dynamic decision. [...] Read more.
The generation of high-quality maritime samples is gradually becoming a key and challenging issue, due to the data thirst for training maritime intelligent models. However, existing methods mainly focus on static sample generation, which cannot meet the requirements of algorithms for dynamic decision. In this paper, an innovative method for generating high-quality marine dynamic data is proposed based on diffusion models. Considering the sensitivity of the diffusion model to prompts, a text enhancement module is first designed to perform semantic enhancement on the input text from the perspective of an expert in maritime climatology. Meanwhile, a directional image editing module is proposed to extract masks of interest from the input image, resulting in separate sea surface and sky regions. Then the image, mask and the enhanced text are sent together into the diffusion model to generate a high-quality directionally edited image. Finally, a video generation diffusion model is designed to convert the edited image into a dynamic data sequence. The entire framework has a clear sense of hierarchy and stable generation effect. We performed quantitative and qualitative experiments to prove that our method has significant advantages in data quality and controllability against existing SOTA methods. Full article
(This article belongs to the Special Issue Advanced Studies in Marine Data Analysis)
Show Figures

Figure 1

37 pages, 19621 KB  
Review
Unveiling the Landscape of Human Pose Estimation
by Jianjun Yang, Sankarshan Dasgupta, Wenjiao Liu, Ju Shen, Bryson R. Payne, Ying Luo, Ruixu Liu and Tam V. Nguyen
Appl. Sci. 2026, 16(12), 6242; https://doi.org/10.3390/app16126242 (registering DOI) - 22 Jun 2026
Viewed by 48
Abstract
Human pose estimation (HPE) has advanced rapidly with deep learning, enabling a transition from specialized sensing and multi-view systems toward monocular RGB-based approaches. These developments have expanded applications in healthcare, robotics, sports analytics, and human–computer interaction. However, the growing diversity of deep learning [...] Read more.
Human pose estimation (HPE) has advanced rapidly with deep learning, enabling a transition from specialized sensing and multi-view systems toward monocular RGB-based approaches. These developments have expanded applications in healthcare, robotics, sports analytics, and human–computer interaction. However, the growing diversity of deep learning paradigms, ranging from convolutional and recurrent models to graph-based and Transformer-based approaches, has resulted in a fragmented literature, making it difficult to systematically compare methods and guide system design. This paper addresses this challenge by providing a comprehensive survey of deep learning-based monocular HPE methods published over the past decade and introducing a unified modular framework. The proposed framework organizes HPE systems into six modular estimation paradigms, including single-image-based estimation, multi-frame-based estimation, Top-Down and Bottom-Up pose estimation strategies, 2D-to-3D pose reconstruction, and direct 3D estimation. Each module is analyzed in terms of representative approaches, design trade-offs, and practical considerations, supported by algorithmic formulations that outline the computational pipeline at each stage. Unlike prior surveys that primarily catalog methods or report benchmark results in isolation, this work emphasizes how component-level design choices relate to overall system performance. The paper summarizes performance trends on benchmarks including Human3.6M, COCO, and MPII, highlighting persistent challenges such as occlusion and viewpoint variation, and outlines future research directions including interaction-aware modeling, efficient deployment, and improved robustness under real-world conditions. Full article
(This article belongs to the Section Computing and Artificial Intelligence)
Show Figures

Figure 1

12 pages, 1991 KB  
Article
HyperDecouple_Net: A Decoupling Algorithm for Crosstalk in 2D Spectral Images
by Zewei Chen and Qiong Chen
Universe 2026, 12(6), 186; https://doi.org/10.3390/universe12060186 (registering DOI) - 22 Jun 2026
Viewed by 51
Abstract
This paper addresses the imaging crosstalk problem in 2D spectra from the LAMOST Phase II upgrade, caused by increased fiber density. We propose HyperDecouple_Net, a hypernetwork-based decoupling algorithm designed to overcome key limitations of existing deep learning models, including overlapping-layer collapse and structural [...] Read more.
This paper addresses the imaging crosstalk problem in 2D spectra from the LAMOST Phase II upgrade, caused by increased fiber density. We propose HyperDecouple_Net, a hypernetwork-based decoupling algorithm designed to overcome key limitations of existing deep learning models, including overlapping-layer collapse and structural distortion. The method integrates an adaptive overlapping-layer enhancement module, a dual-scale hypernetwork differential decoupling module, and a linear consistency constraint module. Additionally, we introduce LAMOST-SD-2026, a public dataset comprising 15,500 linearly superimposed spectral samples with ground-truth labels, derived from real LAMOST Phase I observations. Experimental results on this dataset show that HyperDecouple_Net achieves superior performance, with a PSNR_A of 12.71 dB, PSNR_B of 10.87 dB, SSIM_B of 0.3895, and SAM of 0.4841, outperforming both traditional methods (e.g., NMF, ICA) and recent deep learning approaches. The proposed method can be directly integrated into the LAMOST Phase II preprocessing pipeline, offering a robust solution for high-precision spectral decoupling and supporting the scientific output of the survey. Full article
(This article belongs to the Special Issue Applications of Artificial Intelligence in Modern Astronomy)
Show Figures

Figure 1

18 pages, 5557 KB  
Article
Super-Resolution 3D Imaging Reveals Disarray of Dyadic Calcium Ion Channels in Failing Hearts Expressing Low Thyroid Hormone Function
by Atieh Ashkezari, Megha Schmalzle, Amanda Charest, Sanketh Kumar, Riddhi Modi, Nicholas Nasta, Andrea Bertolini, Alessandro Saba, Paolo Cifani, Youhua Zhang, A. Martin Gerdes, Randy F. Stout and Kaie Ojamaa
Int. J. Mol. Sci. 2026, 27(12), 5601; https://doi.org/10.3390/ijms27125601 (registering DOI) - 21 Jun 2026
Viewed by 169
Abstract
Ventricular remodeling occurring in heart failure (HF) involves structural disarray of the sarcolemma T-tubule (TT)–sarcoplasmic reticulum (SR) dyad junctions, thereby disrupting the close apposition of L-type Ca2+ channels (CaV1.2) with ryanodine receptors (RyR2) that trigger SR Ca2+ release and [...] Read more.
Ventricular remodeling occurring in heart failure (HF) involves structural disarray of the sarcolemma T-tubule (TT)–sarcoplasmic reticulum (SR) dyad junctions, thereby disrupting the close apposition of L-type Ca2+ channels (CaV1.2) with ryanodine receptors (RyR2) that trigger SR Ca2+ release and myofilament contraction. In a rat ischemic heart failure model expressing low thyroid hormone (TH) function, we used 3D stochastic optical reconstruction microscopy (STORM) to image RyR2 clusters with CaV1.2 channels, and the associated protein junctophilin-2 (Jph2). We tested whether treatment with T3, the biologically active form of TH, throughout progression of the disease would preserve T-tubule structure and dyadic ion channel organization. Confocal microscopy of isolated cardiomyocytes (CMs) stained with ANEPPS membrane dye showed significantly decreased TT density in diseased CMs while T3 treatment attenuated TT disorganization. 3D STORM images of dyadic ion channels labeled with fluorescent-tagged antibodies to RyR-Dylight550, Jph-CF647 and CaV1.2/IgG-Dylight488 were captured. A density-based algorithm defined RyR2 clusters, and a 400 nm spherical 3D volume of interest around each RyR2 cluster’s centroid determined the number of CaV1.2 and Jph2 localizations associated with each RyR2 cluster. Analysis revealed significant reduction in RyR2 cluster size and number with reduced co-localized Jph2 in failing CMs. T3 treatment increased RyR2 cluster numbers and cluster volumes albeit non-significantly, with increased co-clustering of Jph2. The number of CaV1.2 co-localized with RyR2 clusters trended lower in the failing CMs. These results support maintaining TH homeostasis in optimizing the nanoscale organization of Ca2+ ion channels in triggering Ca2+ release and myofibrillar contraction in patients with heart disease. Full article
(This article belongs to the Special Issue The Role of Ion Channels in Health and Disease)
Show Figures

Figure 1

Back to TopTop