Search Results (21)

The flowers of Pueraria lobate (Puerariae Flos) have served as a traditional Chinese medicinal and food herbage plant for many years. Tectoridin is one of the most active metabolites extracted from flowers of Pueraria lobate and has a variety of beneficial activities, including antioxidative, hypoglycemic, and anti-inflammatory activities. Nevertheless, the functions and potential mechanisms underlying tectoridin in cerebral ischemia/reperfusion injury have not been well interpreted; thus, a network analysis strategy was performed to systematically evaluate its pharmacological mechanisms, which were further validated in rats with cerebral ischemia. Network analysis predicted that tectoridin could attenuate brain damage after stroke by modulating signaling pathways associated with redox, inflammation, and autophagy. The experimental results demonstrated an improvement in neurological function in rats treated with tectoridin, along with a significant reduction in cerebral infarction volume. The neuroprotective benefits of tectoridin stem, in part, from its antioxidant capabilities, which include the upregulation of Nrf2/HO-1 protein expression, reduction of the TLR4/MYD88/NF-κB inflammatory pathway, and inhibition of the PI3K/Akt/mTOR pathway, contributing to its anti-apoptotic effects. This investigation offers a thorough examination of the pathways and targets linked to the therapeutic effects of tectoridin on ischemic stroke, highlighting its anti-inflammatory, antioxidative, and anti-apoptotic mechanisms. These findings serve as a valuable reference for the development and exploration of effective anti-ischemic stroke medications. Full article

We tested for a forage allowance effect on the milk yield of early lactation dairy cow herds grazing swards sown with perennial ryegrass (Lolium perenne L.), white clover (Trifolium repens L.) and plantain (Plantago lanceolata L.) relative to perennial ryegrass alone. The examined allowances consisted of offering 12, 14, 16, 18, 20 or 25 kg of dry matter (DM)/cow per day of grazeable herbage, with diverse swards sown as mixtures and spatially adjacent monocultures. After adapting cows to their assigned forage type for 8 days, treatment effects on milk yield and composition, blood metabolites (beta-hydroxybutyrate, non-esterified fatty acids and urea concentrations), body weight change, forage intake and selection differentials for forage species and certain nutrients were monitored over 7 days. We confirmed a forage allowance effect on milk yield improvements in dairy cows grazing diverse swards relative to perennial ryegrass monocultures. Improvements in milk yield were evident at forage allowances of 14 to 20 kg of DM/cow per day, diminishing at the highest allowance of 25 kg of DM/cow per day. Improvements in milk yield for the mixture and spatially adjacent monocultures peaked at forage allowances of 18 and 16 kg of DM/cow per day, equalling increases of 1.3 and 1.2 kg of milk/cow per day, respectively. Full article

The objectives of this study were to evaluate the effects of (1) protein supplementation strategy, (2) cow genotype and (3) an interaction between protein supplementation strategy and cow genotype on milk production and nitrogen (N) utilisation efficiency (milk N output/ total dietary N intake × 100; NUE) in late-lactation, spring-calving grazing dairy cows. A 2 × 2 factorial arrangement experiment, with two feeding strategies [13% (lower crude protein; LCP) and 18% CP (higher CP; HCP) supplements with equal metabolisable protein supply] offered at 3.6 kg dry matter/cow perday, and two cow genotype groups [lower milk genotype (LM) and higher milk genotype (HM)], was conducted over 53 days. Cows were offered 15 kg dry matter of grazed herbage/cow/day. Herbage intake was controlled using electric strip wires which allowed cows to graze their daily allocation-only. There was an interaction for herbage dry matter intake within cows offered HCP, where higher milk genotype (HM) cows had increased herbage dry matter intake (+0.58 kg) compared to lower milk genotype (LM) cows. Offering cows LCP decreased fat + protein yield (−110 g) compared to offering cows HCP. Offering cows LCP decreased the total feed N proportion that was recovered in the urine (−0.007 proportion units) and increased the total feed N proportion that was recovered in the faeces (+0.008 proportion units) compared to offering cows HCP. In conclusion, our study shows that reducing the supplementary CP concentration from 18% to 13% resulted in decreased milk production (−9.8%), reduced partitioning of total feed N to urine (−0.9%) and increased partitioning of total feed N to faeces (+14%) in late lactation, grazing dairy cows. Full article

More frequent harvesting of grass swards provides an opportunity to improve the nutritive value of grass silage. This study investigated the effect of offering silages produced within either a three- (3H) or four-harvest (4H) system on dairy cow performance when concentrate supplements were offered according to the individual cow’s milk yield (feed-to-yield). Cows (n = 80) were allocated to either 3H or 4H at calving and remained on experiment for 25 weeks. Within both treatments, cows were offered silage from each harvest consecutively in proportion to the dry matter (DM) yield for each harvest. Silage was offered as a mixed ration with concentrate added at a rate of 8 kg/cow/day. Additional concentrates were offered on a feed-to-yield basis. Herbage yields were reduced in the 4H system, but 4H silage contained higher metabolisable energy and crude protein content compared to 3H. Cows offered the 4H silage had greater silage DM intake, milk yield and milk protein content, while milk fat content was greater in cows offered 3H silages. In conclusion, increasing harvesting frequency from three to four harvests per year can improve silage feed value, silage intakes and milk yields when concentrates are offered on a feed-to-yield basis. Full article

Adaptivity of eating and rumination behavior are assumed to play a particular role for cows in low-input systems, because they are more frequently challenged by altering forage quality. The present study examined relations between forage quality, chewing behavior and efficiency estimates in dairy cows from Swiss zero-concentrate organic farming systems. A total of 102 Swiss Fleckvieh cows on two organic dairy farms were observed during one full production year. Each farm was visited eight times. At each visit, up to 45 cows were equipped with RumiWatch^® (Itin and Hoch GmbH, Liestal, Switzerland) sensor head collars, from which eating and rumination time and the frequency of activity changes were obtained for 48 h. Milk from one complete day was analyzed individually. All offered roughages (pasture herbage, grass silages and hay) were sampled at each visit and analyzed for crude fiber, crude protein and net energy, and a feed quality score was calculated. Metabolic production efficiency was estimated based on entire lactation data, and feed efficiency was estimated based on the individual farm visits. Lactation stage and forage quality significantly affected the chewing sensor variables. Eating time increased and rumination time decreased with the improved nutritive quality of feed. Coefficients of variance of the factor animal in the sensor variables showed a contribution of the individual cow to chewing behavior. Significant correlations between chewing sensor variables and efficiency estimates were not found. In conclusion, chewing behavior under on-farm conditions in low-input dairy farms alters during lactation and during changing forage quality, with significant animal effects, indicating potential for new phenotypes, albeit with no indications for efficiency. Full article

We assessed the effects of high-intensity and low-frequency (HILF) vs. low-intensity and high-frequency (LIHF) grazing on herbage production and performance of beef cattle grazing sorghum pastures. The experimental design was a complete randomized block with two treatments and four replicates (paddocks), carried out in 2014/15. The management target of 50 and 30 cm for pre- and post-grazing, respectively, a LIHF grazing management strategy oriented to maximize beef cattle herbage intake per unit time, was compared with a HILF grazing management strategy of 80 and 20 cm for pre- and post-grazing, respectively, aiming to maximize herbage accumulation and harvest efficiency. Sixteen Brangus steers of 15-month-old and 265 ± 21 kg of live weight (LW) were randomly distributed to paddocks (experimental units). The LIHF resulted in shorter rest periods when compared with the HILF. The greater leaf lamina mass in LIHF allowed greater sward light interception at post-grazing, resulting in greater total herbage production than HILF (7581 and 4154 kg DM/ha, respectively). The average daily gain (ADG) of steers was greater for the LIHF than for the HILF treatment (0.950 and 0.702 kg/animal, respectively); however, even with a greater stocking rate in the HILF, there was no difference for LW gain per ha, with an average of 4 kg LW/ha/day. Our findings demonstrated that the LIHF strategy that is based on offering to the animals an optimal sward structure to favor the maximum herbage intake rate fosters greater herbage production, harvesting efficiency, and ADG without compromising LW gain per area of beef steers, despite the lower herbage harvested per stocking cycle. Full article

The changing climate, water scarcity, reduction in the land area under forage crops, expanding ruminant population, burgeoning demands for milk and meat production and food security concerns all insist on a necessary increase in forage production and quality. Cereal–legume mixed intercropping offers a biologically superior option to boost herbage yield and quality of preserved fodder (hay and silage), provided that rationalization of the component crop’s proportional ratio is performed. Therefore, the current study was conducted to determine the forage yield and quality of barley (Hordeum vulgare L.) and pea (Pisum sativum L.) mixtures at the ratios 100:0, 75:25, 50:50, 25:75 and 0:100. The experiment was laid out in the regular arrangement of a randomized complete block design with three replicates. The results exhibited that forage quality was significantly affected by the mixture ratio. There was a significant improvement in protein, fiber rate and digestibility from the mixture. The ratios of barley and pea with 50:50 and 25:75 produced the maximum productivity and the best quality of forage. Regarding forage preservation, silage recorded higher contents of crude protein, ash and lower fiber contents than hay. Among seed mixtures, 0:100 ratio of barley–pea yielded the highest quality of silage with the maximum crude protein, ash and digestibility with lowest fiber contents. Full article

Data on soil ingestion in horses are lacking in contrast to other free-range animals. The importance of soil as a vector for environmental pollutants to food is less relevant in horses but several disorders secondary to soil ingestion, such as sand colic or enteritis have been reported. Therefore, soil ingestion has been studied on Irish sport horses grazing at three offered levels of daily herbage: 2, 3 and 4% of their body weight. Soil ingestion was estimated by the faecal recovery of a soil natural marker. Horses had 4.5, 4.1 and 3.7% of soil in their total intake respectively for the 2, 3 and 4% herbage offers. The 4% offer presented significantly less intake (543 g/d) compared to the more restricted offers (624 and 648 g respectively for 3 and 2%). The post-grazing sward height was significantly lower on the 2% offer (3.1 cm) compared to the higher offers (4.1 and 4.4 cm respectively for 3 and 4%). Thus, restricted herbage allowance made grazing closer to the ground and increased soil ingestion. The sward height appeared to be a reliable indicator to manage animal withdrawal from a pasture to limit soil ingestion and the risk of gastrointestinal pathologies caused by it. Full article

Sheep liveweight and liveweight change are vital tools both for commercial and research farm management. However, they can be unreliable when collection procedures are not standardized or when there are varying time delays between sheep removal from grazing and weighing. This study had two stages with different objectives: (1) A liveweight loss study to determine the effect of herbage availability (Low and High) on the rate of liveweight loss of ewes at different pregnancy stages (approximately 100 days of pregnancy: P100 and 130 days: P130) and ranks (single and twin); (2) A follow-up liveweight loss study to develop and validate correction equations for delayed liveweights by applying them to data sets collected under commercial conditions. Results from each stage showed that the rate of liveweight loss varied by herbage availability and stage of pregnancy (p < 0.05) but not pregnancy-rank (p > 0.05). Further, the rate of liveweight loss differed by farm (p < 0.05). Applying liveweight correction equations increased the accuracy of without delay liveweight estimates in P100 ewes by 56% and 45% for single-bearing and twin-bearing ewes, respectively, when offered the Low-level diet. In ewes offered the High-level diet, accuracies of without delay liveweight estimates were increased by 53% and 67% for single-bearing and twin-bearing ewes, respectively. Among P130 ewes, accuracy was increased by 43% and 37% for single-bearing and twin-bearing ewes, respectively, when offered the Low herbage level and by 60% and 50% for single-bearing and twin-bearing ewes, respectively, when offered the High herbage level. In conclusion, a short-term delay of up to 8 hours prior to weighing, which is commonly associated with practical handling operations, significantly reduced the liveweight recorded for individual sheep. Using delayed liveweights on commercial farms and in research can have consequences for management practices and research results; thus, liveweight data should be collected without delay. However, when this is not feasible, delayed ewe liveweights should be corrected and, in the absence of locally devised correction equations, the ones generated in the current study could be applied on farms with similar management conditions and herbage type. Full article

The economics of grazing dairy cows offered a range of herbage allowances and fed supplements as a partial mixed ration (PMR) were examined where profit was defined as the margin between total milk income and the cost of pasture plus PMR supplement. The analysis made use of milk production and feed intake data from two dairy cow nutrition experiments, one in early lactation and the other in late lactation. In early lactation and at a PMR intake of 6 kg DM/cow per day, the profit from the cows with access to a medium herbage allowance (25 kg DM/cow per day) was AUD 1.40/cow per day higher than that for cows on a low allowance (15 kg DM/cow per day). At a higher PMR intake of 14 kg DM/cow per day, the profit from the cows on a medium herbage allowance was AUD 0.45/cow per day higher than the cows on a low allowance; there was no additional profit from increasing the herbage allowance from medium to high (40 kg DM/cow per day). In late lactation, the profit from the cows fed a PMR with a medium herbage allowance (20 kg DM/cow per day) was only higher than the cows on a low allowance (12 kg DM/cow per day) when the PMR intake was between 6 and 12 kg DM/cow per day. There was also a difference of AUD +0.50/cow per day between the PMR with medium and high herbage allowance (32 kg DM/cow per day). It was concluded that farmers who feed a PMR to dairy cows should offer at least a medium herbage allowance to optimize profit. While feeding additional PMR increases milk production and profit, further gains would be available by offering a higher herbage allowance. These findings provide an estimate of the net benefits of different herbage allowances when feeding a PMR and will enable farmers to manage their feeding systems more profitably. Full article

Sheep (Ovis aries) liveweight and liveweight change can contain errors when collection procedures are not standardized, or when there are varying time delays between removal from grazing and weighing. A two-stage study was conducted to determine the effect of herbage availability and season of year on the rate of liveweight loss during fasting and to develop and validate correction equations applied to sets of delayed liveweights collected under commercial conditions. Results showed that ewe lambs offered the Low herbage availability lost up to 1.7 kg and those offered the Medium or High herbage availability lost 2.4 kg during 8 h of delayed weighing without access to feed or drinking water. The rate of liveweight loss varied by season, herbage availability and farm (p < 0.05). Applying correction equations on matching liveweight data collected under similar conditions, provided more accurate estimates (33–55%) of without delay liveweight than using the delayed liveweight. In conclusion, a short-term delay prior to weighing commonly associated with practical handling operations significantly reduced the liveweight recorded for individual sheep. Using delayed liveweights on commercial farms and in research can have significant consequences for management practices and research results globally, therefore, liveweight data should be collected without delay. However, when this is not feasible delayed liveweights should be corrected, and in the absence of locally formulated correction equations, the ones presented in this paper could be used. Full article

Plantain (Plantago lanceolata) and chicory (Cichorium intybus) are now widely used in combination with clover species to provide greater annual lamb live weight gains than perennial ryegrass and white clover pasture. Reported selective grazing of the species in herb-clover mixes could potentially detrimentally change the relative abundance of species and decrease lamb production. Lambs were offered three herbage treatments: Pasture (perennial ryegrass and white clover) mix, plantain (plantain, red clover and white clover) mix and a chicory (chicory, plantain, red clover and white clover) mix in each of four seasons for two years. The experiment was a randomized complete block design with three replicates with 18–30 lambs per treatment replicate depending on the season. Lambs were rotationally grazed and fed ad libitum. Selection by the lambs of individually tagged plants within the pasture treatments was observed for three days on two occasions per season. Red clover was the most selected species on day 1, but by day 3 there was no difference in the selection of the species (p < 0.05). Plantain and chicory in the plantain and chicory mixes were selected less on day 1 in autumn relative to the other seasons (p < 0.05). It was concluded that three days of grazing before moving lambs maintained the relative abundance of species in the herb-clover mixes. Full article

Land dedicated to livestock contributes at least 40% of the global agricultural output. While advances in the application of geospatial information systems and remote sensing technologies offer much to agriculture, capturing and using that rich spatial biophysical information is not a feature available in most farm systems models. In this paper, we tackle this gap describing a land-based integrated grazing farm optimisation and resource allocation model (AgInform^®) that departs from the use of whole farm and average data, to the integration of biological data obtained directly from each of the land units within the farm. The model allows the exploration of the dynamics of biophysical and financial performance of the farm in a steady-state, single-year approach, where the opening and closing values of the biological elements of the farm system conditions must remain the same (e.g., animal numbers, herbage mass), unless otherwise specified. The user supplies pasture growth rates, minimum and maximum acceptable pasture masses for each land management unit (LMU), differential boundary conditions to deliver defined environmental outcomes, animal performance (sheep, beef and deer), farm costs and market prices. The linear programming (LP) equations formed by AgInform^® can be divided into a single objective and constraints (which accommodate the boundaries), including those placed on individual LMUs. The optimization routine uses this information to identify the mix of livestock production enterprises that maximises profit for the business. The model in maintaining the link between available pasture mass and livestock requirements for each LMU throughout all calculations, enables the livestock type and number carried, along with the pasture mass required on each LMU throughout the year to achieve the required animal performance levels to be included as model outputs. A hill land sheep and beef farm consisting of seven distinct LMUs was used as a farm-level case to assess if AgInform^® (1) has sufficient flexibility to integrate biological information from each LMU; (2) could use the specified livestock performance targets to derive a feasible livestock policy that optimised resource use and farm returns; (3) can assign each fortnight animal type and number and herbage mass to each LMU; and (4) can mimic reality to produce credible solutions. Full article

In temperate regions of Europe where grass grows for most of the year, grazed pasture is the lowest cost feed for milk production. Grazed pasture can make a contribution to dairy cow feeding systems in other parts of Europe, but is less important. While there are many challenges to maintaining or increasing the proportion of grazed grass in dairy cow diets, there are also opportunities to increase its contribution. Grass use and quality can be challenging for several reasons, including the cow and sward interaction, and factors influencing dry matter intake. Adapting grazing management strategies can provide opportunities for incorporating grazing and perhaps increase grazing in dairy cow milk production systems. Pasture management tools and techniques offer the opportunity to increase herbage use at grazing. While there are many benefits of grazing including economic, environmental, animal welfare and social, there are also the challenges to maintaining grazed pasture in dairy cow diets. The objective of this paper is to present an overview of the challenges and opportunities for grazing in dairy milk production systems. Full article

Due to its extremely harsh environment, including high altitude, hypoxia, long cold season, and strong ultraviolet radiation in the Qinghai–Tibet Plateau (QTP), herbage species and nutritional value of the pasture may differ considerably from elsewhere across the world. The aim of the present study was to develop biologically relevant equations for estimating the metabolizable energy (ME) value of fresh native herbages in the QTP using digestibility variables and chemical concentrations in the herbage offered to Tibetan sheep at the maintenance level. A total of 11 digestibility trials (6 sheep/trial) were performed in different grazing seasons from 2011 to 2016. The herbage was harvested daily in the morning and offered to sheep at the maintenance feeding level. Thirty-seven equations were developed for the prediction of herbage digestible energy (DE) and ME energy values. The mean prediction error for ME was the lowest when using herbage gross energy digestibility as a sole predictor. When using other digestibility variables (e.g., dry matter and organic matter) as primary predictors, addition of herbage nutrient concentration reduced the difference between predicted and actual values. When DE was used as the primary explanatory variable, mean prediction error was reduced with the addition of ash, nitrogen (N), diethyl ether extract (EE), neutral detergent fiber (NDF), and acid detergent fiber (ADF) concentrations. The internal validation of the present equations showed lower prediction errors when compared with those of existing equations for prediction of DE and ME concentrations in the herbage. Equations developed in the current study may thus allow for an improved and accurate prediction of metabolizable energy concentrations of herbage in practice, which is critical for the development of sustainable grazing systems in the QTP. Full article