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Keywords = health literacy event

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11 pages, 262 KiB  
Article
Use of a Peer Equity Navigator Intervention to Increase Access to COVID-19 Vaccination Among African, Caribbean and Black Communities in Canada
by Josephine Etowa, Ilene Hyman and Ubabuko Unachukwu
Int. J. Environ. Res. Public Health 2025, 22(8), 1195; https://doi.org/10.3390/ijerph22081195 - 31 Jul 2025
Viewed by 261
Abstract
African, Caribbean, and Black (ACB) communities face increased COVID-19 morbidity and mortality, coupled with significant barriers to vaccine acceptance and uptake. Addressing these challenges requires innovative, multifaceted strategies. Peer-led interventions, grounded in critical health literacy (CHL) and critical racial literacy (CRL), and integrating [...] Read more.
African, Caribbean, and Black (ACB) communities face increased COVID-19 morbidity and mortality, coupled with significant barriers to vaccine acceptance and uptake. Addressing these challenges requires innovative, multifaceted strategies. Peer-led interventions, grounded in critical health literacy (CHL) and critical racial literacy (CRL), and integrating collaborative equity learning processes, can enhance community capacity, empowerment, and health outcomes, contributing to long-term health equity. This paper describes and presents the evaluative outcomes of a peer-led intervention aimed at enhancing COVID-19 vaccine confidence and acceptance. The Peer-Equity Navigator (PEN) intervention consisted of a specialized training curriculum grounded in CHL and CRL. Following training, PENs undertook a 5-month practicum in community or health settings, engaging in diverse outreach and educational activities to promote vaccine literacy in ACB communities. The evaluation utilized a modified Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) Framework, using quantitative and qualitative methods to collect data. Sources of data included tracking records with community feedback, and a PEN focus group, to assess program feasibility, outreach, and effectiveness. From 16 September 2022, to 28 January 2023, eight trained PENs conducted 56+ community events, reaching over 1500 community members. Both PENs and community members reported high engagement, endorsing peer-led, community-based approaches and increased vaccine literacy. The PEN approach proves feasible, acceptable, and effective in promoting positive health behaviors among ACB communities. This intervention has clear implications for health promotion practice, policy, and research in equity-deserving communities, including immigrants and refugees, who also face multiple and intersecting barriers to health information and care. Full article
16 pages, 1816 KiB  
Article
A New Genre of Digital Texts That Explore Children’s Frame of Mind, Health Literacy Skills, and Behavioral Intentions for Obesity Prevention
by Valerie A. Ubbes
Children 2025, 12(6), 663; https://doi.org/10.3390/children12060663 - 22 May 2025
Viewed by 375
Abstract
Background: This project focuses on the relevance of using a health literacy approach to educating children about obesity prevention. The Habits of Health and Habits of Mind© model was used to write Electronic Texts for Health Literacy© to encourage actions that support obesity [...] Read more.
Background: This project focuses on the relevance of using a health literacy approach to educating children about obesity prevention. The Habits of Health and Habits of Mind© model was used to write Electronic Texts for Health Literacy© to encourage actions that support obesity prevention. Guided by the Integrative Theory of Behavioral Prediction, the design template for a new genre of digital texts called Electronic Texts for Health Literacy© emerges for exploring children’s frame of mind, health literacy skills, and behavioral intentions toward obesity prevention. Methods: Online materials from selected websites were strategically reviewed for improving obesity prevention and child health literacy. The digital resources were juxtaposed with the Electronic Texts for Health Literacy©, with the latter written by and for children. Discussion: Health educators who use a constructivist pedagogy can help students to write health literacy narratives about obesity prevention, then read and talk about their multimodal compositions to further the practice and development of their health literacy skills. Children with obesogenic body frames can also gain from cowriting visual–textual–gestural health narratives with their peers or health professionals. Co-constructed narratives can help children make deeper connections about their identity, frame of mind, and social agency. Summary: Although this untested resource is available as a new genre of digital text, health educators could nudge children toward developing a stronger frame of mind and behavioral intentions toward obesity prevention when they write health literacy narratives that focus on decision making, goal setting, and communication in the context of eating nutritious foods and participating in physical activities. Full article
(This article belongs to the Section Global Pediatric Health)
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11 pages, 244 KiB  
Article
Environmental Health Literacy of Brazilian Indigenous People
by Bernardo Oliveira Buta, Wauana Sheeva Costa Silva Manchineri, Matheus Britto Froner, Maria Berta Ecija, Debora Helena Rosa Cardoso and Benjamin Miranda Tabak
Int. J. Environ. Res. Public Health 2025, 22(4), 625; https://doi.org/10.3390/ijerph22040625 - 17 Apr 2025
Viewed by 617
Abstract
Environmental health literacy (EHL) is essential for individuals to protect themselves from environmental health risks. Indigenous populations are particularly vulnerable to these risks, given the historical threats they have suffered from the advance of agricultural frontiers and impacts of deforestation, mining, and extreme [...] Read more.
Environmental health literacy (EHL) is essential for individuals to protect themselves from environmental health risks. Indigenous populations are particularly vulnerable to these risks, given the historical threats they have suffered from the advance of agricultural frontiers and impacts of deforestation, mining, and extreme weather events. This study investigates the dimensions of EHL among indigenous communities in Brazil, considering the scarcity of research in this field. Using a scale adapted to measure EHL in topics such as air, water, and food, it was possible to access the EHL levels of a sample of different Brazilian indigenous ethnic groups. Statistical analysis included descriptive methods and the Wilcoxon and Kruskal–Wallis tests. The results revealed significant variations in EHL levels, influenced by factors such as gender, place of residence, age, education, access to health services, and potable water. In addition, the presence of traditional actors, such as midwives, was identified as an important factor in the transmission of health knowledge. The research highlights the need for public policies that respect the cultural specificities of indigenous communities and promote self-care and environmental preservation, contributing to the development of culturally sensitive public health strategies. Full article
(This article belongs to the Section Environmental Health)
10 pages, 1155 KiB  
Article
Evaluation of Secondary Prevention Knowledge in Patients with Coronary Artery Disease
by Gabriel Bálint and Zuzana Slezáková
Medicina 2025, 61(4), 693; https://doi.org/10.3390/medicina61040693 - 10 Apr 2025
Viewed by 669
Abstract
Background and Objectives: Most patients with cardiovascular disease have limited health literacy and knowledge. The promotion of knowledge among patients with coronary artery disease is an integral part of health maintenance and the minimisation of secondary cardiac events. The aim of this [...] Read more.
Background and Objectives: Most patients with cardiovascular disease have limited health literacy and knowledge. The promotion of knowledge among patients with coronary artery disease is an integral part of health maintenance and the minimisation of secondary cardiac events. The aim of this study was to map the percent proportion of answers and scores obtained from them in the studied domains. Materials and Methods: In this cross-sectional study, a Coronary Artery Disease Education Questionnaire (CADE-Q II) was used to verify knowledge gaps in the five studied domains. In total, 253 patients with coronary artery disease completed the CADE-Q II, which targeted five domains: health status, risk factors, exercise, nutrition and psychosocial risk. Data were collected between June 2021 and November 2024. Results: An analysis of the data found a total mean CADE-Q II score of 61.05 ± 11.42 SD out of 93 points. Our research showed that the total mean score of a group of patients corresponded to an acceptable level of knowledge. Patients in the cohort provided a total of 7843 responses for the five study domains. In total, 46.8% of patients scored all answers correctly in terms of risk factors, 49.0% in terms of nutrition, 53.1% in terms of health status, 64.4% in terms of psychosocial risk, and 65.0% in terms of exercise. Conclusions: The use of the CADE-Q II questionnaire, with its focus on the studied domains, verifies patient knowledge and provides a foundation for education, the provision of effective information and the promotion of secondary prevention knowledge. Full article
(This article belongs to the Special Issue Advances in Chronic Coronary Syndrome and Coronary Heart Disease)
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24 pages, 287 KiB  
Review
Telemedicine for Managing Type 1 Diabetes in Children and Adolescents Before and After the COVID-19 Pandemic
by Federica Fogliazza, Vanessa Sambati, Brunella Iovane, Pietro Lazzeroni, Maria Elisabeth Street and Susanna Esposito
J. Clin. Med. 2024, 13(23), 7359; https://doi.org/10.3390/jcm13237359 - 3 Dec 2024
Viewed by 2156
Abstract
The COVID-19 pandemic has catalyzed the rapid expansion of telemedicine for managing chronic conditions such as type 1 diabetes (T1D) in children and adolescents. This narrative review aims to explore the role of telemedicine in pediatric T1D management by comparing its use before [...] Read more.
The COVID-19 pandemic has catalyzed the rapid expansion of telemedicine for managing chronic conditions such as type 1 diabetes (T1D) in children and adolescents. This narrative review aims to explore the role of telemedicine in pediatric T1D management by comparing its use before and after the pandemic. We conducted a comprehensive literature review covering studies published between 2000 and 2024, focusing on telemedicine applications in pediatric T1D care. The review includes clinical trials, systematic reviews, and observational studies examining telemedicine’s impact on glycemic control, patient satisfaction, and healthcare delivery. Results reveal that telemedicine has enhanced access to care, improved glycated hemoglobin (HbA1c) levels, and reduced diabetic ketoacidosis and hypoglycemic events. Patients and caregivers expressed high satisfaction, especially when using continuous glucose monitoring and insulin pump technologies integrated with telemedicine platforms. However, challenges such as digital literacy gaps, variability in healthcare provider training, and logistical issues like reimbursement policies persist. The pandemic highlighted the potential of telemedicine to supplement traditional in-person care, showing promise in enhancing patient outcomes and reducing healthcare burdens. Further research is needed to optimize telemedicine models for T1D, addressing barriers to implementation and exploring its long-term cost-effectiveness. This review underscores telemedicine’s evolving role as a complementary approach in managing pediatric T1D, advocating for the development of standardized care protocols to fully integrate digital health solutions into routine clinical practice. Full article
(This article belongs to the Special Issue New Insights into Type 1 Diabetes)
19 pages, 1136 KiB  
Article
Assessing the Effects of Citizen Climate Literacy and Attitudes on Their ‘Greening’ Behaviour in a Climate Change Hotspot Region of the Eastern Mediterranean
by Katerina Papagiannaki, Vassiliki Kotroni and Konstantinos Lagouvardos
Climate 2024, 12(9), 146; https://doi.org/10.3390/cli12090146 - 19 Sep 2024
Cited by 1 | Viewed by 2209
Abstract
Climate change presents an urgent global challenge, manifesting in rising temperatures and extreme weather events with severe societal impacts. The Eastern Mediterranean, warming faster than the global average, faces immediate repercussions. Climate literacy emerges as pivotal, empowering individuals to comprehend climate science and [...] Read more.
Climate change presents an urgent global challenge, manifesting in rising temperatures and extreme weather events with severe societal impacts. The Eastern Mediterranean, warming faster than the global average, faces immediate repercussions. Climate literacy emerges as pivotal, empowering individuals to comprehend climate science and act accordingly. This study delves into climate literacy, attitudes, and ‘greening’ behaviours in the Eastern Mediterranean hotspot of Greece, based on a survey of 1962 citizens. Findings indicate high climate literacy but lower adoption of ‘greening’ behaviours, especially those involving financial costs. Regression analyses highlight the significant role of climate literacy, concerns about personal impacts, coping appraisal, and trust in institutions in promoting ‘greening’ behaviours. This study underscores the need for multifaceted strategies emphasising financial motivation, trust-building, and societal norm shifts. Socio-demographic disparities, including gender and occupation, highlight areas for targeted interventions. The emphasis on the mental health impacts of climate-related events underscores the need for comprehensive disaster management that addresses not only physical damage but also psychological and social dimensions. Policy implications are discussed, highlighting the potential of expanded climate literacy to catalyse collective action toward sustainability. Full article
(This article belongs to the Special Issue Climate Variability in the Mediterranean Region)
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11 pages, 238 KiB  
Article
Examining Communicative, Critical Health Literacy and eHealth Literacy among International University Students Residing in Japan
by Ishtiaq Ahmad, Hira Taimur, Sameera Shabbir, Chaudhry Ahmed Shabbir, Ali Ahsan, Hafiz Sultan Ahmad and Gaku Masuda
Healthcare 2024, 12(9), 941; https://doi.org/10.3390/healthcare12090941 - 4 May 2024
Cited by 4 | Viewed by 2433
Abstract
(1) Background: International students with sufficient health literacy are better equipped to respond to public health emergencies and reduce any unintentional harm that may occur during such events. This study aims to assess the current status of health literacy among international students and [...] Read more.
(1) Background: International students with sufficient health literacy are better equipped to respond to public health emergencies and reduce any unintentional harm that may occur during such events. This study aims to assess the current status of health literacy among international students and investigate the factors that influence health literacy. (2) Methods: A cross-sectional study was conducted in Tokyo on international university students using a questionnaire consisting of the Communicative and Critical Health Literacy and eHealth Literacy Scales. The study analyzed 205 valid responses. Descriptive statistics were utilized to assess the level of health literacy, and linear regression was used to identify the association of socio-demographic characteristics and disease status with health and e-health literacy. (3) Results: Health literacy and e-health literacy were low in 48.29% and 47.29% of international students, respectively. The mean scores of CCHL items ranged from 3.13 to 3.26, while the mean scores of eHEALS items ranged from 3.33 to 3.49. Both health literacy and e-health literacy were better with unmarried status (p = 0.015), and e-health literacy was worse with higher age (p = 0.007). (4) Conclusions: Overall, international students’ health literacy and e-health literacy were at intermediate levels, with considerable room for improvement, and affected by certain student attributes. Full article
13 pages, 1626 KiB  
Review
From Health-in-All-Policies to Climate-in-All-Policies: Using the Synergies between Health Promotion and Climate Protection to Take Action
by K. Viktoria Stein and Thomas E. Dorner
Int. J. Environ. Res. Public Health 2024, 21(1), 110; https://doi.org/10.3390/ijerph21010110 - 18 Jan 2024
Cited by 5 | Viewed by 3313
Abstract
The climate crisis is developing into a life-changing event on a global level. Health promotion with the aim to increase the health status of individuals, independent of the present health status, has been developed on a scientific basis at least for the last [...] Read more.
The climate crisis is developing into a life-changing event on a global level. Health promotion with the aim to increase the health status of individuals, independent of the present health status, has been developed on a scientific basis at least for the last eight decades. There are some basic principles which are prerequisites for both health promotion and climate protection. Those principles include (1) sustainability, (2) orientation on determinants, and (3) requirement of individual as well as community approaches. People are generally aiming to protect their lifestyle habits (e.g., traveling and consumer habits) and personal property (e.g., car and house) with easy solutions and as little effort as possible, and this can affect both health and climate. To reduce the emission of greenhouse gases and to protect our environment, changes towards a sustainable lifestyle have to be embedded into everybody’s mind. Examples for domains that need to be addressed in health promotion as well as in climate protection include (health and climate) literacy, physical activity and active mobility, and nutrition and dietary habits. If health promotion fails to tackle those domains, this will continue to drive the climate crisis. And climate change, in turn, will affect health. On the other hand, developing and promoting health resources in the domains mentioned could help to mitigate the health-damaging effects of climate change. Success in the joint efforts to promote health and protect the climate would improve the One Health approach, the health of people and the environment. Full article
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17 pages, 1030 KiB  
Review
Death Unpreparedness Due to the COVID-19 Pandemic: A Concept Analysis
by Cristina Costeira, Maria Anjos Dixe, Ana Querido, Ana Rocha, Joel Vitorino, Cátia Santos and Carlos Laranjeira
Healthcare 2024, 12(2), 188; https://doi.org/10.3390/healthcare12020188 - 12 Jan 2024
Cited by 3 | Viewed by 2657
Abstract
The COVID-19 pandemic imposed changes upon the capacity of healthcare systems, with significant repercussions on healthcare provision, particularly at end-of-life. This study aims to analyze the concept map of death unpreparedness due to the COVID-19 pandemic, capturing the relationships among the attributes, antecedents, [...] Read more.
The COVID-19 pandemic imposed changes upon the capacity of healthcare systems, with significant repercussions on healthcare provision, particularly at end-of-life. This study aims to analyze the concept map of death unpreparedness due to the COVID-19 pandemic, capturing the relationships among the attributes, antecedents, consequences, and empirical indicators. Walker and Avant’s method was used to guide an analysis of this concept. A literature search was performed systematically, between May 2022 and August 2023, using the following electronic databases on the Elton Bryson Stephens Company (EBSCO) host platform: Medical Literature Analysis and Retrieval System Online (Medline), Psychological Information Database (PsycINFO), Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, Cochrane Library, and Nursing and Allied Health Collection. Thirty-four articles were retrieved. The unexpected and unpredictable impositions associated with inexperience and unskillfulness in dealing with COVID-19 configured challenges for healthcare professionals, family/caregivers, and even the dying person. Nine key attributes emerged in three main domains: (1) Individual: (a) disease-related conditions, (b) separation distress, and (c) scarcity of death and grief literacy; (2) Relational: (a) Dying alone, (b) poor communication, and (c) existential issues; and (3) Contextual: (a) disrupted collective mourning and grieving, (b) disrupted compassionate care and, (c) pandemic social stigma. This study contributed a full definition of death unpreparedness in a global pandemic scenario such as COVID-19. In this sense, feeling unprepared or unready for death brought new challenges to the bioecological resources of those affected. It is essential to embrace strategies capable of providing emotional and spiritual support in the dying process and to respect patient wishes. The lessons learned from COVID-19 should be applied to events with a comparable impact to minimize their consequences. Full article
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31 pages, 10208 KiB  
Case Report
Healthy Patients, Workforce and Environment: Coupling Climate Adaptation and Mitigation to Wellbeing in Healthcare
by Mark de Souza, Aunty Bilawara Lee and Stephen Cook
Int. J. Environ. Res. Public Health 2023, 20(22), 7059; https://doi.org/10.3390/ijerph20227059 - 13 Nov 2023
Cited by 3 | Viewed by 5712
Abstract
Climate change threatens the health of all Australians: without adaptation, many areas may become unlivable, in particular the tropical north. The Northern Territory (NT) health workforce is already under colliding operational pressures worsened by extreme weather events, regional staff shortages and infrastructure that [...] Read more.
Climate change threatens the health of all Australians: without adaptation, many areas may become unlivable, in particular the tropical north. The Northern Territory (NT) health workforce is already under colliding operational pressures worsened by extreme weather events, regional staff shortages and infrastructure that is poorly adapted to climate change. The H3 Project (Healthy Patients, Workforce and Environment) explores nature-based interventions in the NT health sector aiming to strengthen the resilience and responsiveness of health infrastructure and workforce in our climate-altered future. The H3 Project engaged the health workforce, climate researchers and the wider community, in recognition that meaningful and timely climate action requires both organization-led and grassroots engagement. We recruited campus greening volunteers and sustainability champions to Royal Darwin Hospital (RDH) to develop strategies that enhance climate adaptation, build climate and health literacy, and incentivize active mobility. We implemented low-cost biophilic design within the constraints of legacy healthcare infrastructure, creating cool and restorative outdoor spaces to mitigate the impacts of heat on RDH campus users and adapt to projected warming. This case study demonstrated substantial cooling impacts and improved local biodiversity and hospital campus aesthetics. We collaborated with Indigenous healers and plant experts to harness the synergy between Aboriginal people’s traditional knowledge and connectedness to land and the modern concept of biophilic design, while seeking to improve hospital outcomes for Indigenous patients who are both disconnected from their homelands and disproportionately represented in NT hospitals. Full article
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17 pages, 343 KiB  
Article
The Awareness of the Role of Commercial Determinants of Health and the Readiness to Accept Restrictions on Unhealthy Food Advertising in Polish Society
by Urszula Zwierczyk, Mateusz Kobryn and Mariusz Duplaga
Nutrients 2023, 15(22), 4743; https://doi.org/10.3390/nu15224743 - 10 Nov 2023
Cited by 5 | Viewed by 2332
Abstract
The negative consequences of commercial determinants of health (CDoH) have become a major challenge for public health systems, especially in terms of non-communicable diseases (NCDs). CDoH are defined as profit-driven factors that influence health. In this study, we assessed the awareness of CDoH [...] Read more.
The negative consequences of commercial determinants of health (CDoH) have become a major challenge for public health systems, especially in terms of non-communicable diseases (NCDs). CDoH are defined as profit-driven factors that influence health. In this study, we assessed the awareness of CDoH and the attitudes toward potential restrictions on advertising, as well as fiscal interventions targeting food products with harmful effects on health in Polish society. Our analysis is based on data from a computer-based web interviewing (CAWI) survey performed in May 2022 among 2008 adult internet users from Poland. Multivariable logistic regression models were developed for variables derived from three items exploring the respondents’ understanding of the relationship between CDoH and NCDs, as well as three items asking about their acceptance of a prohibition of advertising unhealthy products during sports events, a general ban on unhealthy food advertising, and their attitudes toward sugar-sweetened beverages (SSBs). Food (FL) and e-health literacy (eHL) levels were consistently positive predictors of both awareness of CDoH and acceptance of the proposed actions. Both higher FL and eHL were significantly associated with the opinion that advertising unhealthy food is associated with the prevalence of NCDs (OR, 95% CI: 1.03, 1.02–1.05, and 1.04, 1.02–1.06, respectively). Health literacy was less frequently a significant predictor of the dependent variables. Among sociodemographic factors, a respondent’s level of education and age showed a significant relationship with their awareness and acceptance of countermeasures against CDoH. Respondents with a university master’s level of education were more likely to agree with the statement on the relationship between big industry profits and harm to society’s health (OR, 95% CI: 1.96, 1.42–2.69) and to support a ban on advertising unhealthy food similar to that for tobacco products (OR, 95% CI: 1.66, 1.21–2.27). Respondents suffering from chronic diseases were also consistently more likely to show a greater understanding of the harmful impact of CDoH and support proposed restrictions. For example, they were more likely to agree with restrictions on advertising harmful products during sports events (OR, 95% CI: 1.23, 1.02–1.50) and the introduction of a sugar tax (OR, 95% CI: 1.26, 1.03–1.54). Our study revealed that more than 50% of the Polish population is conscious of the problem of the harmful effects of big industries producing and selling processed food, sugar-sweetened beverages, and alcoholic beverages. Interestingly, slightly more than half of the respondents supported the introduction of restrictions on advertising such products. Still, only approximately 30% of them accepted a sugar tax to counter the obesity epidemic. The results of our study indicate that Polish society is open to the introduction of regulations aimed at limiting the impact of commercial determinants of health. To our knowledge, this is one of the first studies to assess the awareness of CDoH and the acceptance of restrictions to limit their impact. Full article
(This article belongs to the Section Nutrition and Public Health)
21 pages, 8283 KiB  
Article
Bloomin’ Ridiculous: Climate Change, Water Contamination and Algal Blooms in a Land Down Under
by Andrea Crampton and Angela T. Ragusa
Hydrology 2023, 10(9), 185; https://doi.org/10.3390/hydrology10090185 - 14 Sep 2023
Cited by 1 | Viewed by 2774
Abstract
Climate and anthropogenic change, particularly agricultural runoff, increase blue-green algae/cyanobacteria blooms. This article researches cyanobacteria alert-level identification, management, and risk communication in Lake Hume, Australia. Two methods, document and content analysis, evidence contamination events and risk communication, reflect water governance and data management [...] Read more.
Climate and anthropogenic change, particularly agricultural runoff, increase blue-green algae/cyanobacteria blooms. This article researches cyanobacteria alert-level identification, management, and risk communication in Lake Hume, Australia. Two methods, document and content analysis, evidence contamination events and risk communication, reflect water governance and data management limitations. Results found that Lake Hume had amber or red alerts for only one week, December 2021–December 2022. This failed to prevent government tourism promotion of recreational usage, contravening water authority red alert advice. Lake-use restrictions lacked compliance enforcement. Events during amber alerts lacked risk communication to vulnerable populations (children). Lake Hume’s governance by the Murray–Darling Basin Authority restricted risk communication to one authority that reproduced generic advice in minimal outlets/time points. Geophysical signage failed to address diversity needs (language, literacy, age, and disabilities). No risk communication was found for residents with diseases exacerbated by aerosolization. Despite WHO promoting cyanotoxin investigation, Australian research is absent in international literature. Further, Lake Hume cyanobacteria produce potentially carcinogenic microcystein. This coexists with census data revealing cancer rates higher than the national average in a waterside town. The results demonstrate the need to incorporate robust public health risk assessments, communication, and management into water management and advocate international legislation changes based on evidence-based research to reduce blooms and prevent agricultural runoff. Full article
(This article belongs to the Special Issue Climate Change Effects on Hydrology and Water Resources)
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13 pages, 1622 KiB  
Article
The Carrier Frequency of Two SMN1 Genes in Parents of Symptomatic Children with SMA and the Significance of SMN1 Exon 8 in Carriers
by Joanne E Davidson, Jacqueline S Russell, Noelia Nunez Martinez, David R Mowat, Kristi J Jones, Edwin P Kirk, Didu Kariyawasam, Michelle Farrar and Arlene D’Silva
Genes 2023, 14(7), 1403; https://doi.org/10.3390/genes14071403 - 6 Jul 2023
Cited by 2 | Viewed by 3313
Abstract
Background: Current carrier screening methods do not identify a proportion of carriers that may have children affected by spinal muscular atrophy (SMA). Additional genetic data is essential to inform accurate risk assessment and genetic counselling of SMA carriers. This study aims to quantify [...] Read more.
Background: Current carrier screening methods do not identify a proportion of carriers that may have children affected by spinal muscular atrophy (SMA). Additional genetic data is essential to inform accurate risk assessment and genetic counselling of SMA carriers. This study aims to quantify the various genotypes among parents of children with SMA. Method: A retrospective cohort study was undertaken at Sydney Children’s Hospital Network, the major SMA referral centre for New South Wales, Australia. Participants included children with genetically confirmed SMA born between 2005 and 2021. Data was collected on parent genotype inclusive of copy number of SMN1 exons 7 and 8. The number of SMN2 exon 7 copies were recorded for the affected children. Descriptive statistics were used to determine the proportion of carriers of 2+0 genotype classified as silent carriers. Chi-square test was used to correlate the association between parents with a heterozygous SMN1 exon 7 deletion and two copies of exon 8 and ≥3 SMN2 copy number in the proband. Results: SMA carrier testing was performed in 118/154 (76.6%) parents, incorporating 59 probands with homozygous SMN1 deletions and one proband with compound heterozygote pathogenic variants. Among parents with a child with SMA, 7.6% had two copies of SMN1 exon 7. When only probands with a homozygous SMN1 exon 7 deletion were included, 6.9% of parents had two copies of SMN1 exon 7. An association was observed between heterozygous deletion of SMN1 exon 7 with two copies of exon 8 in a parent and ≥3 SMN2 copy number in the affected proband (p = 0.07). Conclusions: This study confirmed a small but substantial proportion of silent carriers not identified by conventional screening within an Australian context. Accordingly, the effectiveness of carrier screening for SMA is linked with genetic counselling to enable health literacy regarding high and low risk results and is complemented by new-born screening and maintaining clinical awareness for SMA. Gene conversion events may underpin the associations between parent carrier status and proband SMN2 copy number. Full article
(This article belongs to the Section Human Genomics and Genetic Diseases)
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16 pages, 5312 KiB  
Article
Comparative Study of the Information about the COVID-19 Pandemic and COVID-19 Vaccines on the Covers of United Kingdom, France, Spain and United States’ Main Newspapers
by Santiago Tejedor, Laura Cervi, Fernanda Tusa and Mónica Gracia Villar
Soc. Sci. 2022, 11(9), 412; https://doi.org/10.3390/socsci11090412 - 8 Sep 2022
Cited by 5 | Viewed by 3292
Abstract
This study compares the information coverage of the vaccine against the information of the COVID-19 pandemic in eight newspapers (two per country) from the United Kingdom, France, Spain and the United States. The newspapers analyzed are The Times and The Guardian (United Kingdom), [...] Read more.
This study compares the information coverage of the vaccine against the information of the COVID-19 pandemic in eight newspapers (two per country) from the United Kingdom, France, Spain and the United States. The newspapers analyzed are The Times and The Guardian (United Kingdom), Le Monde and Le Figaro (France), El País and El Mundo (Spain), and The New York Times and The Washington Post (United States). On a methodological level, the work uses a descriptive approach of hemerographic analysis. As a result, it is observed—in the case of coverage of the pandemic—that the presence of affected persons and health personnel in the front-page information was negligible, with a predominance of news journalistic genres (brief and newsworthy, especially), evidencing a leading role of political figures and the high degree of politicization of the crisis. In addition, the visual frames in the analyzed newspapers tended to promote humanization through emotional representation. On the other hand, the results of the news coverage of the vaccine showed a predominance of news journalistic genres, wherein supranational entities and pharmaceutical companies starred in the front pages to a greater extent. The study denotes the importance of media literacy among citizens, especially in the face of this type of informational events of global significance. Full article
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17 pages, 1283 KiB  
Article
What Causes Health Information Avoidance Behavior under Normalized COVID-19 Pandemic? A Research from Fuzzy Set Qualitative Comparative Analysis
by Qingxiu Ding, Yadi Gu, Gongrang Zhang, Xingguo Li, Qin Zhao, Dongxiao Gu, Xuejie Yang and Xiaoyu Wang
Healthcare 2022, 10(8), 1381; https://doi.org/10.3390/healthcare10081381 - 25 Jul 2022
Cited by 7 | Viewed by 3895
Abstract
Affected by the normalization of the COVID-19 pandemic, people’s lives are subject to many restrictions, and they are under enormous psychological and physical pressure. In this situation, health information may be a burden and cause of anxiety for people; thus, the refusal of [...] Read more.
Affected by the normalization of the COVID-19 pandemic, people’s lives are subject to many restrictions, and they are under enormous psychological and physical pressure. In this situation, health information may be a burden and cause of anxiety for people; thus, the refusal of health information occurs frequently. Health-information-avoidance behavior has produced potential impacts and harms on people’s lives. Based on more than 120,000 words of textual data obtained from semi-structured interviews, summarizing a case collection of 55 events, this paper explores the factors and how they combine to lead to avoidance of health information. First, the influencing factors are constructed according to the existing research, and then the fuzzy set qualitative comparative analysis (fsQCA) method is used to discover the configuration relationship of health-information-avoidance behavior. The results show that the occurrence of health-information avoidance is not the result of a single factor but the result of a configuration of health-information literacy, negative emotions, perceived information, health-information presentation, cross-platform distribution, and the network information environment. These findings provide inspiration for reducing the adverse consequences of avoiding health information and improving the construction of health-information service systems. Full article
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