Search Results (4)

Cold forging is widely used in many industries. Multi-stage cold forming is usually utilized in forging fasteners. In this study, numerical simulation and experimental investigations were carried out on a five-stage cold-forming process for the manufacturing of low-carbon steel AISI 1010 relief valve regulating nuts. The forming process through five stages included preparation and centering for backward extrusion, backward extrusion over die pin, upset, backward extrusion over a moving punch, and piercing. The formability of the workpiece was studied, such as the effects on forming force response, maximum forming force, effective stress and effective strain distributions, metal flow patterns, and strength. A comparison of the forming forces obtained in the forming experiment with the numerical simulation results of the five-stage cold forming showed a good agreement with the trend of the forming force growth. For the maximum forming force and forming energy, the fourth stage of backward extrusion over the moving punch at the upper face was the largest among the five stages. The total maximum forming forces from the first to the fifth stages were numerically 440.9 kN and experimentally 449.4 kN, meaning the FE simulation and experimental results were in good agreement. The numerically simulated effective strain distributions were consistent with the experimentally tested hardness distributions. Highly compacted grain flow lines also resulted in higher hardness. The overall hardness of the workpiece formed by five-stage cold forming increased by 31% compared to the initial billet. The hardness of the workpiece increased with the forming stages, and the strain-hardening effect was obvious. The strength of the workpiece was significantly increased by five-stage cold forming. Full article

Primary cilia are non-motile plasma membrane extrusions that display a variety of receptors and mechanosensors. Loss of function results in ciliopathies, which have been strongly linked with congenital heart disease, as well as abnormal development and function of most organ systems. Adults with congenital heart disease have high rates of acquired heart failure, and usually die from a cardiac cause. Here we explore primary cilia’s role in acquired heart disease. Intraflagellar Transport 88 knockout results in reduced primary cilia, and knockout from cardiac endothelium produces myxomatous degeneration similar to mitral valve prolapse seen in adult humans. Induced primary cilia inactivation by other mechanisms also produces excess myocardial hypertrophy and altered scar architecture after ischemic injury, as well as hypertension due to a lack of vascular endothelial nitric oxide synthase activation and the resultant left ventricular dysfunction. Finally, primary cilia have cell-to-cell transmission capacity which, when blocked, leads to progressive left ventricular hypertrophy and heart failure, though this mechanism has not been fully established. Further research is still needed to understand primary cilia’s role in adult cardiac pathology, especially heart failure. Full article

Cu–Zn–Pb brasses are popular materials, from which numerous industrially and commercially used components are fabricated. These alloys are typically subjected to multiple-step processing—involving casting, extrusion, hot forming, and machining—which can introduce various defects to the final product. The present study focuses on the detailed characterization of the structure of a brass fitting—i.e., a pre-shaped medical gas valve, produced by hot die forging—and attempts to assess the factors beyond local cracking occurring during processing. The analyses involved characterization of plastic flow via optical microscopy, and investigations of the phenomena in the vicinity of the crack, for which we used scanning and transmission electron microscopy. Numerical simulation was implemented not only to characterize the plastic flow more in detail, but primarily to investigate the probability of the occurrence of cracking based on the presence of stress. Last, but not least, microhardness in specific locations of the fitting were examined. The results reveal that the cracking occurring in the location with the highest probability of the occurrence of defects was most likely induced by differences in the chemical composition; the location the crack in which developed exhibited local changes not only in chemical composition—which manifested as the presence of brittle precipitates—but also in beta phase depletion. Moreover, as a result of the presence of oxidic precipitates and the hard and brittle alpha phase, the vicinity of the crack exhibited an increase in microhardness, which contributed to local brittleness. Full article

This article discusses the problems related to the use of non-contact 3D scanning techniques and their support by means of replication methods for the analysis of the geometrical changes in deep tool impressions used for the forward extrusion of valve-type elements assigned for motor truck engines. The 3D scanning method, despite its unquestionable advantages, also has certain limitations, such as scanning the inner surfaces of deep cavities. This is caused by the fact that the larger the angle between the reflected laser light and the normal direction to the measured surface, the larger the area covered for the analysis, yet at the same time, the higher the measurement error. The authors performed an analysis of the geometrical loss of the tools as well as the corresponding replication masses, together with a discussion of the results related to minimization of the measuring errors. For the analyzed tool, the maximum angle during direct scanning was 40 degrees, which unfortunately does not enable an analysis of the entire pattern, while for larger angles, it is necessary to make the measurement by indirect scanning, i.e., by replicating the cavity imprint of the tool. Therefore, for a given geometry, the reflection angle should be determined individually. Full article