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15 pages, 258 KB  
Article
Exploring Professionals’ Perceptions of the Potential of Digital Twins in Homecare—A Focus Group Study in Sweden
by Sandra Saade, Susanna Nordin and Johan Borg
Healthcare 2026, 14(3), 289; https://doi.org/10.3390/healthcare14030289 - 23 Jan 2026
Abstract
Background/Objectives: The growing number of older adults with complex healthcare needs increases demand for homecare services, while a shrinking workforce often lacks skills for advanced tasks. Digital health is seen as a promising tool to address these challenges. This study explored Swedish [...] Read more.
Background/Objectives: The growing number of older adults with complex healthcare needs increases demand for homecare services, while a shrinking workforce often lacks skills for advanced tasks. Digital health is seen as a promising tool to address these challenges. This study explored Swedish homecare professionals’ perceptions of the potential use of digital twins in daily work. Methods: Four focus group discussions were conducted with 31 homecare professionals; two groups each in one urban/rural and one rural municipality. Data were analyzed using inductive content analysis. Results: Three main themes emerged: (i) Perceptions of digital twins as support for older adults, including needs-based, individualized care and proactive support enabling preventive measures; (ii) Perceptions of digital twins as support for professionals, including a better work environment through streamlined tasks and flows and enhanced planning and assessment; and (iii) Concerns about digital twins, focusing on ethical and social issues and limited understanding, which were related to monitoring aspects, the importance of physical visits, and how the technology works. Conclusions: Digital twins are perceived by professionals to have the potential to improve homecare services by supporting both older adults and professionals; however, further research is needed to address concerns and practical implications. Full article
(This article belongs to the Special Issue Holistic Approaches to Aging in Place: Health, Safety, and Community)
18 pages, 1385 KB  
Article
Antenatal Care Attendance and Multiple Micronutrient Supplementation Intake: Perspectives from Women and Antenatal Care Service Providers in Rwanda
by Giulia Pastori, Kesso Gabrielle van Zutphen-Küffer, Shashank Sarvan, Yana Manyuk, Elvis Gakuba, Yashodhara Rana, Jack Clift, Kara Weiss, Bonnie Weiss, Xiao-Yu Wang, Aline Uwimana, Claude M. Muvunyi, Eliphaz Tuyisenge, Samson Desie, Melinda K. Munos and Sufia Askari
Nutrients 2026, 18(3), 373; https://doi.org/10.3390/nu18030373 - 23 Jan 2026
Abstract
Background/Objectives: Emerging evidence suggests that multiple micronutrient supplements (MMS) provide additional benefits for maternal and neonatal health compared with iron and folic acid (IFA) supplements. To achieve effective coverage, acceptability, and adherence—and to inform a nationwide rollout of MMS—it is essential to understand [...] Read more.
Background/Objectives: Emerging evidence suggests that multiple micronutrient supplements (MMS) provide additional benefits for maternal and neonatal health compared with iron and folic acid (IFA) supplements. To achieve effective coverage, acceptability, and adherence—and to inform a nationwide rollout of MMS—it is essential to understand the context-specific factors that shape implementation. This study evaluated the pilot implementation of MMS in Rwanda to identify key enablers, areas for improvement, and challenges related to antenatal care (ANC) attendance and MMS use. Methods: Data were collected through a survey of 3257 women who attended ANC services, seven focus group discussions with 35 ANC attendees, and key informant interviews with 20 ANC nurses and 21 community health workers. Results: Pregnant women reported high ANC attendance (74%) and MMS consumption (79%), largely driven by strong motivation and awareness of MMS benefits. Strategies to remember daily intake and to manage side effects supported adherence, as did reminders, motivation, and information from family members and healthcare providers. Limited patient-centered counselling, financial constraints, barriers to accessing ANC services, and product stock-outs were key areas for strengthening service delivery in Rwanda. Conclusions: Sustaining high ANC attendance and MMS adherence as the program transitions from the pilot phase to national scale-up is essential. Improving counseling quality and strengthening supply chains may reinforce ANC services and support sustained MMS adherence, with benefits for maternal and child health. Full article
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19 pages, 915 KB  
Article
Innovation for Sustainable SMEs: How Financial Health Drives Resilience and Long-Term Performance in a Transition Economy
by Teodora Babic, Milorad Katnic, Ivana Katnic, Vladimir Kavaric and Maja Drakic-Grgur
Sustainability 2026, 18(3), 1145; https://doi.org/10.3390/su18031145 - 23 Jan 2026
Abstract
Small- and medium-sized enterprises (SMEs) are central to sustainable development in transition economies, yet their financial fragility often limits resilience and the capacity to invest in innovation and responsible practices. Despite growing interest in SME, financial health and its role in sustainability, empirical [...] Read more.
Small- and medium-sized enterprises (SMEs) are central to sustainable development in transition economies, yet their financial fragility often limits resilience and the capacity to invest in innovation and responsible practices. Despite growing interest in SME, financial health and its role in sustainability, empirical evidence from small transition economies like Montenegro remains scarce, particularly on how liquidity and profitability dynamics underpin conditions for SDG-aligned growth. This study addresses this gap by analyzing how core financial indicators—cash position, capital structure, and working capital efficiency—affect liquidity and profitability among 345 Montenegrin SMEs across manufacturing, services, and trade. Using OLS and robust regression models, results reveal that a higher cash-to-revenue ratio and moderate leverage significantly enhance both short-term solvency and profitability, while working capital efficiency shows nuanced effects and sector-specific patterns emerge in capital-intensive industries. These findings highlight financial management as a foundation for SME resilience, creating financial preconditions for innovation and digital investments in aligned with SDGs (goals 8, 9, 12). Policy recommendations focus on improving finance access and financial literacy to foster innovation-driven, sustainable SME models aligned with the 2030 Agenda. Full article
(This article belongs to the Special Issue Advancing Innovation and Sustainability in SMEs: Insights and Trends)
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16 pages, 1251 KB  
Article
Association of Shift, Day, Month and Year with Mortality: Observational Study of Spanish and USA Emergency Care Cohorts
by Álvaro Astasio-Picado, José Luis Martín-Conty, Begoña Polonio-López, Cristina Rivera-Picón, Maria Eugenia Medina Chozas, Maria del Mar Palazuelos Diaz, Laura Mordillo-Mateos, Francisca Torres-Falguera, Laura Ros Gomez, Paula Alvarez Buitrago, Francisco Martín-Rodríguez and Ancor Sanz-García
Med. Sci. 2026, 14(1), 56; https://doi.org/10.3390/medsci14010056 - 22 Jan 2026
Abstract
Background/Objectives: Emergency medical services (EMSs) are essential for reducing mortality among critically ill patients. This study aims to evaluate the influence of temporal factors, such as time of day, day of the week, month, and year, on mortality in EMS activations, comparing [...] Read more.
Background/Objectives: Emergency medical services (EMSs) are essential for reducing mortality among critically ill patients. This study aims to evaluate the influence of temporal factors, such as time of day, day of the week, month, and year, on mortality in EMS activations, comparing health systems in the U.S. and Spain. Methods: This multicenter observational study, which is based on two databases (Spain’s Sacyl and the U.S.’s NEMSIS), analyzed EMS activation in high-priority adult patients (>18 years) between 2018 and 2023. Demographic variables, transport characteristics, and response times were included. Short-term mortality was the primary outcome. Results: A total of 54,981 EMS activations (11,713 from the Sacyl dataset and 43,268 from the NEMSIS dataset) were analyzed. Mortality was higher among older patients and males, with significant increases during shifts from 06:00 to 12:00 and from 18:00 to 24:00. Mortality also varied by year, with higher rates in 2022 and 2023 than in 2018. Notable differences were observed between the U.S. and Spain, especially in shifts and months, with higher mortality during the 12:00 to 18:00 shift and in October in the NEMSIS cohort. Conclusions: These findings have direct implications for emergency medical service operations, suggesting that resource allocation, staffing models, and clinical protocols should be strategically optimized based on temporal risk patterns to improve patient outcomes during identified high-risk periods. Full article
21 pages, 831 KB  
Article
Exploring the Roles of Age and Gender in User Satisfaction and Usage of AI-Driven Chatbots in Digital Health Services: A Multigroup Analysis
by Latifa Alzahrani and Vishanth Weerakkody
Systems 2026, 14(1), 113; https://doi.org/10.3390/systems14010113 - 22 Jan 2026
Abstract
As chatbot technology becomes increasingly prevalent across a wide range of industries, it is crucial to explore the factors that shape user satisfaction with this AI-driven innovation. This research provides insights into how age and gender impact user perceptions and engagement with AI-driven [...] Read more.
As chatbot technology becomes increasingly prevalent across a wide range of industries, it is crucial to explore the factors that shape user satisfaction with this AI-driven innovation. This research provides insights into how age and gender impact user perceptions and engagement with AI-driven health technologies in Saudi Arabia. The information systems success model has been utilised to determine the effect of age and gender on user satisfaction. A self-administered questionnaire was distributed in two hospitals in Makkah City, Saudi Arabia, and 527 responses were collected from chatbot users. Structural equation modelling via analysis of moment structures validated the model constructs. The findings revealed that the privacy issue on user satisfaction has been significantly greater with males than with females. However, the correlation between user satisfaction and continuance usage intention, as well as net benefits, has been much higher among the females. Also, notable differences were found between user satisfaction and net benefits and continuance usage intention and net benefits, especially when comparing younger and older participants. Across all age groups, user satisfaction consistently emerged as a central driver of continuance usage intention and net benefits, underscoring the importance of fostering satisfaction to enhance the effectiveness of AI-driven chatbots in digital health services. This study can serve as a guide to highlight the importance of chatbot user satisfaction and provide implications, limitations, and future research opportunities. Full article
(This article belongs to the Section Artificial Intelligence and Digital Systems Engineering)
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12 pages, 963 KB  
Article
Training Healthcare Assistants for School-Based Care of Children Receiving Paediatric Palliative Care: A Post-Training Evaluation
by Anna Santini, Anna Marinetto, Enrica Grigolon, Alessandra Fasson, Mirella Schiavon, Igor D’angelo, Nicoletta Moro, Barbara Roverato, Pierina Lazzarin and Franca Benini
Children 2026, 13(1), 153; https://doi.org/10.3390/children13010153 - 22 Jan 2026
Abstract
Background/Objectives: Children in paediatric palliative care often face school attendance barriers due to complex health needs. This study describes post-training perceptions of a training program by a pediatric hospice team to prepare school care assistants to safely include children with complex conditions, [...] Read more.
Background/Objectives: Children in paediatric palliative care often face school attendance barriers due to complex health needs. This study describes post-training perceptions of a training program by a pediatric hospice team to prepare school care assistants to safely include children with complex conditions, focusing on procedural skills, knowledge of the child, and family partnership. Methods: Care assistants who completed a structured course at the Paediatric Palliative Care Centre, University Hospital of Padua (2023–2024), were surveyed immediately after training. The program combined classroom instruction with hands-on simulation using high-fidelity mannequins and standard devices, including suction, pulse oximetry, ventilation, enteral feeding, and tracheostomy care. It also covered modules on urgent and emergency management, as well as family communication. An anonymous online questionnaire gathered socio-demographic data, prior training, clinical tasks performed, self-efficacy levels, and open-ended feedback. Quantitative results were analyzed descriptively, while qualitative comments were subjected to thematic analysis. Results: Of 130 invited assistants, 105 participated (81%). Participants reported strong perceived confidence: 85% selected the upper end of the 5-point scale (“very” or “extremely”) for routine-management ability, and 60% selected these same response options for emergency-management ability. In the most severe events recalled, 60.5% of incidents were resolved autonomously, 7.6% involved contacting emergency services, and 3.8% involved community or hospice nurses. Seventy-five percent judged the course comprehensive; thematic analysis of 102 comments identified satisfaction, requests for regular refreshers, stronger practical components, and requests for targeted topics. Conclusions: Immediately after the session, participants tended to select the upper end of the self-assurance item for both routine and emergency tasks. Combining core emergency procedures with personalized, child-specific modules and family-partnership training may support safety, trust, and inclusion. Regular refreshers and skills checks are advised. Full article
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17 pages, 1838 KB  
Article
Responsiveness to City Service Requests, Life Satisfaction, and Horizontal Inequality: Does Good Local Governance Improve Subjective Well-Being for All?
by Danyel P. L. Tharakan and Tiffany N. Ford
Int. J. Environ. Res. Public Health 2026, 23(1), 132; https://doi.org/10.3390/ijerph23010132 - 21 Jan 2026
Viewed by 62
Abstract
Local governance has been found to be an important determinant of individuals’ subjective well-being (SWB) in cross-municipality studies in Europe and Asia. In addition, previous literature suggests that increasing access to determinants of SWB provides lesser SWB benefit to racial minorities compared to [...] Read more.
Local governance has been found to be an important determinant of individuals’ subjective well-being (SWB) in cross-municipality studies in Europe and Asia. In addition, previous literature suggests that increasing access to determinants of SWB provides lesser SWB benefit to racial minorities compared to white people in the United States (U.S.). Given this context, we ask the following: (1) does good local governance improve SWB in the U.S.? and (2) does good local governance improve SWB for Black and Hispanic people equally compared to white people? To answer these questions, we examine Chicago, Illinois, the third-largest city in the U.S. with substantial Black and Hispanic populations. We model local governance, our independent variable, as the number of weeks for the municipality to respond to pothole service requests reported to the city’s non-emergency services system. Our dependent variable was life satisfaction, measured by the Cantril Ladder. Covariates included self-reported health problems, lack of money for food, sex, age, age-squared, and marital status. Neighborhood race/ethnicity was tested as a moderator of the primary relationships. We estimated linear regression models with and without race × governance interactions. Our findings demonstrate that local governance is an important determinant of SWB, but that it benefits SWB in white neighborhoods more than in Black/Hispanic neighborhoods. Full article
(This article belongs to the Section Behavioral and Mental Health)
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18 pages, 314 KB  
Article
Building Capacity in Crisis: Evaluating a Health Assistant Training Program for Young Rohingya Refugee Women
by Nada Alnaji, Bree Akesson, Ashley Stewart-Tufescu, Md Golam Hafiz, Shahidul Hoque, Farhana Ul Hoque, Rayyan A. Alyahya, Carine Naim, Sulafa Zainalabden Alrkabi, Wael ElRayes and Iftikher Mahmood
Int. J. Environ. Res. Public Health 2026, 23(1), 127; https://doi.org/10.3390/ijerph23010127 - 20 Jan 2026
Viewed by 327
Abstract
Background: The Rohingya refugee crisis is one of the largest humanitarian emergencies of the 21st century, with nearly one million Rohingya residing in overcrowded camps in southern Bangladesh. Women and children face the greatest vulnerabilities, including inadequate access to education and healthcare, which [...] Read more.
Background: The Rohingya refugee crisis is one of the largest humanitarian emergencies of the 21st century, with nearly one million Rohingya residing in overcrowded camps in southern Bangladesh. Women and children face the greatest vulnerabilities, including inadequate access to education and healthcare, which exacerbates their risks and limits opportunities for personal and community development. While international organizations continue to provide aid, resources remain insufficient, particularly in maternal and child healthcare, highlighting the urgent need for sustainable interventions. Objectives: The Hope Foundation for Women and Children in Bangladesh launched a pilot project for the Health Assistant Training (HAT) program to address critical gaps in healthcare and education for the Rohingya community. This nine-month training program equips young Rohingya women with essential knowledge and skills to support maternal health services in both clinical and community settings. Design: We conducted a qualitative evaluation of the HAT Program to explore its acceptance and anticipated benefits for both participants and the community. Methods: The research team used semi-structured interviews, focus groups, and field observations to explore the HAT Program’s impact on young Rohingya women and their community. They analyzed data through thematic analysis, developing a coding framework and identifying key themes to uncover patterns and insights. Results: The results were categorized into four themes: (1) community acceptance of the HAT Program, (2) the HAT Program’s impact on the health assistant trainees, (3) the impact of the HAT Program on the community, and (4) the potential ways to expand the HAT Program. Conclusions: This research underscores the program’s impact on improving healthcare access, enhancing women’s empowerment, and promoting community resilience. By situating this initiative within the broader context of refugee health, education, and capacity-building, this research highlights the HAT program’s potential as a replicable model in Bangladesh and in other humanitarian settings. Full article
14 pages, 342 KB  
Article
Impact of Psychiatric Rehabilitation on Chronicity and Health Outcomes in Mental Disorders: A Quasi-Experimental Study
by Marta Llorente-Alonso, Marta Tello Villamayor, Estela Marco Sainz, Pilar Barrio Íñigo, Lourdes Serrano Matamoros, Irais Esther García Villalobos, Irene Cuesta Matía, Andrea Martínez Abella, María José Velasco Gamarra, María Nélida Castillo Antón and María Concepción Sanz García
Healthcare 2026, 14(2), 250; https://doi.org/10.3390/healthcare14020250 - 20 Jan 2026
Viewed by 124
Abstract
Background/Objectives: People suffering from mental illnesses are more likely to experience adverse social and health outcomes. Various interventions have been shown to help people with mental illness achieve better results in terms of symptom reduction, functional status, and quality of life. Psychiatric [...] Read more.
Background/Objectives: People suffering from mental illnesses are more likely to experience adverse social and health outcomes. Various interventions have been shown to help people with mental illness achieve better results in terms of symptom reduction, functional status, and quality of life. Psychiatric rehabilitation interventions integrate evidence-based practices, promising approaches, and emerging methods that can be effectively implemented to enhance health outcomes in this population. This study aims to examine whether the rehabilitative treatment provided to a group of patients with mental illness leads to improvements in health outcomes and psychiatric symptomatology. Methods: This study employed a retrospective quasi-experimental design. Data were collected between 2023 and 2025 within the Partial Hospitalization Program of the Psychiatry and Mental Health Service of Soria (Spain). The sample consisted of 58 participants who received rehabilitative treatment in this setting. Data were collected at the time of patients’ admission and at discharge. Gender, age, psychiatric diagnosis according to ICD-10, and the average length of stay in the rehabilitation program were assessed. The questionnaires administered were psychometrically validated scales related to heteroaggressiveness, perceived quality of life, global functioning, attitudes toward medication, and the risk of suicide. Results: A significant improvement was observed in the Global Assessment of Functioning (GAF) Scale (t = −7.1, p < 0.001), with mean scores increasing from 42.17 at admission to 69.13 at discharge. Additionally, reductions in suicidal risk and hetero-aggressive behavior were noted, alongside improvements in quality of life and treatment adherence. Conclusions: The findings highlight the effectiveness of implementing activities and programs focused on psychiatric rehabilitation processes to promote positive health outcomes. Future research directions and practical implications are discussed to support the continued development and optimization of psychiatric rehabilitation programs. Full article
(This article belongs to the Special Issue Multidisciplinary Approaches to Chronic Disease Management)
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16 pages, 801 KB  
Article
Development of Deep Learning Models for AI-Enhanced Telemedicine in Nursing Home Care
by Nuria Luque-Reigal, Vanesa Cantón-Habas, Manuel Rich-Ruiz, Ginés Sabater-García, Álvaro Cosculluela-Fernández and José Luis Ávila-Jiménez
J. Clin. Med. 2026, 15(2), 828; https://doi.org/10.3390/jcm15020828 - 20 Jan 2026
Viewed by 87
Abstract
Background/Objectives: Acute health events in institutionalized older adults often lead to avoidable hospital referrals, requiring rapid, accurate remote decision-making. Telemedicine has become a key tool to improve assessment and care continuity in nursing homes. This study aimed to evaluate outcomes associated with telemedicine-supported [...] Read more.
Background/Objectives: Acute health events in institutionalized older adults often lead to avoidable hospital referrals, requiring rapid, accurate remote decision-making. Telemedicine has become a key tool to improve assessment and care continuity in nursing homes. This study aimed to evaluate outcomes associated with telemedicine-supported management of acute events in residential care facilities for older adults and to develop a deep learning model to classify episodes and predict hospital referrals. Methods: A quasi-experimental study analyzed 5202 acute events managed via a 24/7 telemedicine system in Vitalia nursing homes (January–October 2024). The dataset included demographics, comorbidities, vital signs, event characteristics, and outcomes. Data preprocessing involved imputation, normalization, encoding, and dimensionality reduction via Truncated SVD (200 components). Given the imbalance in referral outcomes (~10%), several resampling techniques (SMOTE, SMOTEENN, SMOTETomek) were applied. A deep feedforward neural network (256–128–64 units with Batch Normalization, LeakyReLU, Dropout, AdamW) was trained using stratified splits (70/10/20) and optimized via cross-validation. Results: Telemedicine enabled the resolution of approximately 90% of acute events within the residential setting, reducing reliance on emergency services. The deep learning model outperformed traditional algorithms, achieving its best performance with SMOTEENN preprocessing (AUC = 0.91, accuracy = 0.88). The proposed model achieved higher overall performance than baseline classifiers, providing a more balanced precision–specificity trade-off for hospital referral prediction, with an F1-score of 0.63. Conclusions: Telemedicine-enabled acute care, strengthened by a robust deep learning classifier, offers a reliable strategy to enhance triage accuracy, reduce unnecessary transfers, and optimize clinical decision-making in nursing homes. These findings support the integration of AI-assisted telemedicine systems into long-term care workflows. Full article
(This article belongs to the Section Geriatric Medicine)
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16 pages, 1167 KB  
Article
Demographic Factors and Trends Associated with Mortality After AIDS Diagnosis in Puerto Rico
by Grisel Burgos-Barreto, Daniel Reyes and Raymond L. Tremblay
Infect. Dis. Rep. 2026, 18(1), 13; https://doi.org/10.3390/idr18010013 - 20 Jan 2026
Viewed by 64
Abstract
Background: Millions of people have died from AIDS-related illnesses since the start of the epidemic. The objective of this study is to determine the relationship between life years lost and demographic factors in the subset of individuals in Puerto Rico with advanced HIV [...] Read more.
Background: Millions of people have died from AIDS-related illnesses since the start of the epidemic. The objective of this study is to determine the relationship between life years lost and demographic factors in the subset of individuals in Puerto Rico with advanced HIV disease, i.e., who received a diagnosis of AIDS, and to evaluate trends in poverty, age, and number of diagnoses and deaths over this timeframe. Methods: We identified 3624 individuals diagnosed with AIDS who received services under the Eligible Metropolitan Area (EMA) of San Juan, Puerto Rico, between 2000–2020, and correlated demographic factors with AIDS descriptive statistics using a retrospective cohort study design. We used socioeconomic characteristics to describe the population, estimated the life years lost (LYL) compared with the life expectancy of the general population of Puerto Rico at a given age as the null model, and evaluated the relationship of demographic variables with LYL, as well as trends in poverty and age/number of deaths/diagnoses over time. Results: More life years are lost with earlier AIDS onset, and there is also an association between LYL and the level of poverty, documented mode of transmission, and insurance status. LYL were higher among AIDS patients with lower income, with perinatal transmission, and among those without insurance in the age bracket of 40–49 years. No relationship between LYL and gender was detected. Moreover, over the years included in the timeframe of this study, certain trends emerged: we observed a greater proportion of AIDS to HIV diagnoses over time; HIV/AIDS diagnoses and deaths occurred on average at a higher age; the number of diagnoses per year initially rose over time and then declined; and the number of deaths per year as well as the poverty level in those diagnosed with HIV/AIDS increased over time. Conclusions: This study demonstrates the continued recent impact of the HIV epidemic specifically on those with advanced disease (AIDS), and further reaffirms the importance of treatment and prevention as well as demographic and social determinants of health, including age, poverty level, insurance status, and lifestyle, highlighting the disproportionate burden of HIV/AIDS among those with greater levels of poverty. Full article
(This article belongs to the Section Sexually Transmitted Diseases)
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11 pages, 625 KB  
Review
Type B Aortic Dissection Management Strategies: National Survey, Systematic Review, and Pooled Clinician Perceptions
by Ali Kordzadeh and Karen May Rhodes
J. Vasc. Dis. 2026, 5(1), 2; https://doi.org/10.3390/jvd5010002 - 20 Jan 2026
Viewed by 69
Abstract
Background: Type B Aortic Dissection (TBAD) management relies on risk stratification, yet evidence-based tool adoption remains inconsistent in National Health Services (NHSs). Bridging the gap between Emergency Medicine (EM) and Vascular Surgery remains essential for timely diagnosis, optimal risk stratification, and appropriate [...] Read more.
Background: Type B Aortic Dissection (TBAD) management relies on risk stratification, yet evidence-based tool adoption remains inconsistent in National Health Services (NHSs). Bridging the gap between Emergency Medicine (EM) and Vascular Surgery remains essential for timely diagnosis, optimal risk stratification, and appropriate intervention to improve outcomes and reduce mortality. Methods: A cross-sectional survey of EM consultants yielded n = 173 valid responses from n = 33 units across the UK. Subgroup analyses were conducted using a Chi-square test (p < 0.05) alongside descriptive analysis. A pooled prevalence analysis of the literature, utilizing a random-effects model at a 95% confidence interval (CI), served as a benchmark for perception analysis. Agreement was evaluated using Bland–Altman analysis, incorporating upper, lower, and overall bias of agreeability. Results: Access to a rapid Computed Tomography Angiogram (CTA) was 70% (95% CI: 63.3–76.8%, p < 0.001), while 32% had standard operating procedures (SOPs) for TBAD (95% CI: 25.3–39.1%), and 26% were aware of any decision tool (95% CI: 20.6–33.6%). Labetalol as a first-line antihypertensive was more common amongst least experience (p < 0.05). TBAD diagnosis increased 1.6-fold with every 4 years of additional experience (p < 0.05). Perception analysis showed strong agreement for pain (characteristics and location), hypertension, gender, and age with moderate-to-low agreement for other factors with a reported bias of 23.58% (−38.20% to 85.36%) (p = 0.02). Conclusions: The survey suggests a degree of misperception and inconsistency in recognition of most and least prevalence factors for TBAD suspicion and management. This outcome advocates targeted strategies to enhance diagnostic accuracy using tools aligned with NHS resources and QALY frameworks. Furthermore, upon recognition of the most prevalent factors, CTA and specialist referral is advocated. Full article
(This article belongs to the Section Cardiovascular Diseases)
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16 pages, 220 KB  
Article
Climate-Conscious Medication Therapy Management: Perspectives of Canadian Primary Care Pharmacists
by Zubin Austin and Paul Gregory
Climate 2026, 14(1), 17; https://doi.org/10.3390/cli14010017 - 15 Jan 2026
Viewed by 159
Abstract
(1) Background: The climate impact of health care work has raised interest in climate-conscious health care practice. Medications contribute significantly to the carbon footprint; there has been insufficient work describing climate-conscious medication therapy management practices that could be useful to address climate change [...] Read more.
(1) Background: The climate impact of health care work has raised interest in climate-conscious health care practice. Medications contribute significantly to the carbon footprint; there has been insufficient work describing climate-conscious medication therapy management practices that could be useful to address climate change caused by health care work. (2) Methods: This exploratory qualitative research study focused on climate-conscious medication therapy management practices. A semi-structured interview protocol was used. A total of 17 primary care pharmacists were interviewed (following informed consent) to the point of thematic saturation. A constant-comparative analysis was undertaken to identify and categorize themes. The research was undertaken based on a protocol approved by the University of Toronto Research Ethics Board. (3) Result: Three main themes emerged: (a) There is insufficient evidence currently available to guide climate conscious medication therapy management; (b) seven specific climate-conscious medication therapy management strategies were identified as being most likely to be acceptable by primary care pharmacists; (c) medication therapy management services focused on climate adaptation strategies for patients should be expanded; (4) Conclusions: As medications become the primary intervention used in health care, climate-conscious medication therapy management becomes more essential than ever. Further work in providing evidence to guide climate-conscious prescribing decisions is needed. Full article
(This article belongs to the Section Climate Adaptation and Mitigation)
12 pages, 566 KB  
Article
Low Back Pain Characteristics Among Health Science Undergraduates: A Prospective Study for 2-Year Follow Up
by Janan Abbas, Saher Abu-Leil, Kamal Hamoud and Katherin Joubran
J. Clin. Med. 2026, 15(2), 684; https://doi.org/10.3390/jcm15020684 - 14 Jan 2026
Viewed by 160
Abstract
Background/Objectives: Low back pain (LBP) is one of the most prevalent musculoskeletal disorders globally, significantly impacting quality of life across diverse populations. Despite its association with middle-aged and older populations, evidence indicates that LBP is increasingly prevalent among younger age groups. Health science [...] Read more.
Background/Objectives: Low back pain (LBP) is one of the most prevalent musculoskeletal disorders globally, significantly impacting quality of life across diverse populations. Despite its association with middle-aged and older populations, evidence indicates that LBP is increasingly prevalent among younger age groups. Health science students are considered a potential risk factor for LBP; however, longitudinal studies are scarce. This study aims to determine the risk factors for LBP among health science students over a 2-year follow-up. Methods: One hundred ninety-seven of the third-class health science students (Nursing, Physiotherapy, Medical laboratory science, and Emergency Medical services) were contacted in June 2024. A self-administered modified version of the Standardized Nordic Questionnaire, and data about sedentary and physical activity behavior, as well as 1-month LBP (lasting at least 12 h and numeric rating scale > 5) and stress scores, were recorded. Results: A total of 172/197 (87.3%) respondents completed the questionnaire at the end of the 2-year follow-up. The mean age was 25 ± 3.5 (years) and body mass index (BMI) value 23.5 ± 4.3 (kg/m2). About 49% (n = 84) and 20% (n = 34) of the participants had 1-month LBP and functional disability, respectively. No significant association was found between health science programs and the presence of 1-month LBP (χ2 = 0.55, p > 0.05). The logistic regression analyses found that males (OR = 0.269, p = 0.005) and a history of pain frequency (OR = 3.377, p = 0.001) had a significant association with LBP over time. Conclusions: This prospective study shows a high prevalence of 1-month LBP (48.8%) among health science students at Zefat Academic College. LBP was significantly related to sex (female) and pain frequency, but not to health science students. We believe that implementing ergonomic and educational strategies is recommended for this population. Full article
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Article
Epidemiological and Clinical Characteristics Associated with Antimicrobial-Resistant Urinary Tract Infections in Outpatient and Inpatient Settings: A Retrospective Study from Northwestern Mexico
by Jose Monroy-Higuera, Uriel A. Angulo-Zamudio, Nidia Leon-Sicairos, Hector Flores-Villaseñor, Jorge Velazquez-Roman, Ernesto Ruiz-Trejo, Julio Medina-Serrano, Francisco Castro-Apodaca, Gabriela Tapia-Pastrana and Adrian Canizalez-Roman
Pathogens 2026, 15(1), 92; https://doi.org/10.3390/pathogens15010092 - 14 Jan 2026
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Abstract
Antimicrobial resistance in urinary tract infections (UTIs) poses a critical public health challenge, yet comparative data between outpatient and inpatient settings remain limited, particularly in Latin America. This study characterized the epidemiology, microbiology, and resistance patterns of UTIs in northwestern Mexico. A retrospective [...] Read more.
Antimicrobial resistance in urinary tract infections (UTIs) poses a critical public health challenge, yet comparative data between outpatient and inpatient settings remain limited, particularly in Latin America. This study characterized the epidemiology, microbiology, and resistance patterns of UTIs in northwestern Mexico. A retrospective analysis of 1041 patients with UTI (May–November 2024) was conducted. Microorganism identification and antimicrobial susceptibility were determined using the MicroScan WalkAway system in accordance with CLSI guidelines. Results: Outpatients accounted for 80.5% of cases and inpatients for 19.4%, with a 3.1% mortality rate. Escherichia coli predominated (62.9%), with a significant association with outpatients (p = 0.02), whereas Enterobacter cloacae, Acinetobacter spp., Candida tropicalis, and C. albicans were associated with inpatients (p < 0.05). Pediatric patients exhibited distinctive microbiological profiles: Pseudomonas aeruginosa (9.7% vs. 2.1%, p = 0.032), Enterococcus faecalis (33.3% vs. 16.2%, p = 0.001), and Staphylococcus epidermidis (26.6% vs. 6.5%, p = 0.027) were significantly more prevalent than in adults. Multidrug resistance (MDR) was detected in 27.1% of isolates, and extensive drug resistance (XDR) in 3.2%. XDR was associated with Gram-positive bacteria (12.2% vs. 1.4%, p < 0.001). Carbapenem-resistant Enterobacteriaceae (CRE) were identified in 0.9% (7/772) of cases, with 42.9% occurring in outpatients. Hospitalization (OR: 2.01; 95% CI: 1.43–2.83), surgical services (OR: 1.41; 95% CI: 1.02–1.97), and recent surgery (OR: 2.37; 95% CI: 1.04–5.39) were independent predictors of MDR/XDR infections. Conclusions: These findings demonstrate the emergence of CRE within the community and distinctive pediatric resistance patterns, underscoring the need for tailored antimicrobial stewardship strategies in this region. Full article
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