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Search Results (6,577)

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Keywords = detection and tracking

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16 pages, 2847 KB  
Article
Characterization of the Extraction System of Supersonic Gas Curtain-Based Ionization Profile Monitor for FLASH Proton Therapy
by Farhana Thesni Mada Parambil, Milaan Patel, Narender Kumar, Bharat Singh Rawat, William Butcher, Tony Price and Carsten P. Welsch
Instruments 2026, 10(1), 4; https://doi.org/10.3390/instruments10010004 (registering DOI) - 25 Jan 2026
Abstract
FLASH radiotherapy requires real-time, non-invasive beam monitoring systems capable of operating under ultra-high dose rate (UHDR) conditions without perturbing the therapeutic beam. In this work, we characterized the extraction system of Supersonic Gas Curtain-based Ionization Profile Monitor (SGC-IPM) for its capabilities as a [...] Read more.
FLASH radiotherapy requires real-time, non-invasive beam monitoring systems capable of operating under ultra-high dose rate (UHDR) conditions without perturbing the therapeutic beam. In this work, we characterized the extraction system of Supersonic Gas Curtain-based Ionization Profile Monitor (SGC-IPM) for its capabilities as a transverse beam profile and position monitor for FLASH protons. The monitor utilizes a tilted gas curtain intersected by the incident beam, leading to the generation of ions that are extracted through a tailored electrostatic field, and detected using a two stage microchannel plate (MCP) coupled to a phosphor screen and CMOS camera. CST Studio Suite was employed to conduct electrostatic and particle tracking simulations evaluating the ability of the extraction system to measure both beam profile and position. The ion interface, at the interaction region of proton beam and gas curtain, was modeled with realistic proton beam parameters and uniform gas curtain density distributions. The ion trajectory was tracked to evaluate the performance across multiple beam sizes. The simulations suggest that the extraction system can reconstruct transverse beam profiles for different proton beam sizes. Simulations also supported the system’s capability as a beam position monitor within the boundary defined by the beam size, the dimensions of the extraction system, and the height of the gas curtain. Some simulation results were benchmarked against experimental data of 28 MeV proton beam with 70 nA average beam current. This study will further help to optimize the design of the extraction system to facilitate the integration of SGC-IPM in medical accelerators. Full article
(This article belongs to the Special Issue Plasma Accelerator Technologies)
48 pages, 1184 KB  
Systematic Review
Machine Learning, Neural Networks, and Computer Vision in Addressing Railroad Accidents, Railroad Tracks, and Railway Safety: An Artificial Intelligence Review
by Damian Frej, Lukasz Pawlik and Jacek Lukasz Wilk-Jakubowski
Appl. Sci. 2026, 16(3), 1184; https://doi.org/10.3390/app16031184 - 23 Jan 2026
Abstract
Ensuring robust railway safety is paramount for efficient and reliable transportation systems, a challenge increasingly addressed through advancements in artificial intelligence (AI). This review paper comprehensively explores the burgeoning role of AI in enhancing the safety of railway operations, focusing on key contributions [...] Read more.
Ensuring robust railway safety is paramount for efficient and reliable transportation systems, a challenge increasingly addressed through advancements in artificial intelligence (AI). This review paper comprehensively explores the burgeoning role of AI in enhancing the safety of railway operations, focusing on key contributions from machine learning, neural networks, and computer vision. We synthesize current research that leverages these sophisticated AI methodologies to mitigate risks associated with railroad accidents and optimize railroad tracks management. The scope of this review encompasses diverse applications, including real-time monitoring of track conditions, predictive maintenance for infrastructure components, automated defect detection, and intelligent systems for obstacle and intrusion detection. Furthermore, it delves into the use of AI in assessing human factors, improving signaling systems, and analyzing accident/incident reports for proactive risk management. By examining the integration of advanced analytical techniques into various facets of railway operations, this paper highlights how AI is transforming traditional safety paradigms, paving the way for more resilient, efficient, and secure railway networks worldwide. Full article
21 pages, 11494 KB  
Article
Attention-Guided Track-Pulse-Sequence Target Association Network
by Yiyun Hu, Wenjuan Ren, Yixin Zuo and Zhanpeng Yang
Sensors 2026, 26(3), 774; https://doi.org/10.3390/s26030774 (registering DOI) - 23 Jan 2026
Abstract
Multi-satellite sequential detection is crucial for maritime target identification and tracking. However, inherent satellite revisit patterns and maritime target motion often result in fragmented track segments, necessitating effective multi-satellite track association to ensure continuity. Existing methods predominantly rely on track information and statistical [...] Read more.
Multi-satellite sequential detection is crucial for maritime target identification and tracking. However, inherent satellite revisit patterns and maritime target motion often result in fragmented track segments, necessitating effective multi-satellite track association to ensure continuity. Existing methods predominantly rely on track information and statistical signal parameters, rendering them susceptible to localization errors and ineffective in scenarios characterized by dense targets and overlapping radar parameters. To overcome these limitations, this paper proposes an attention-guided track-pulse-sequence target association network (AG-TPS-TAN). First, the asymmetric dual-branch network operates by incorporating both track data and electromagnetic signal data, processing the latter in the form of raw pulse sequences instead of the conventional statistical parameters. Second, within the track branch, we enhance the feature representation by incorporating a novel track-point-aware attention mechanism which can autonomously identify and weight critical points indicative of motion continuity, such as interruption boundaries and maneuvering points. Third, we introduce a dual-feature fusion module optimized with a combined loss function, which pulls feature representations of the same target closer together while pushing apart those from different targets, thereby enhancing both feature consistency and discriminability. Experiments were conducted on a public AIS trajectory dataset, constructing a dataset containing both motion trajectories and electromagnetic signals. Evaluations under varying target numbers showed that the proposed AG-TPS-TAN achieved average association accuracies of 93.91% for 5 targets and 63.83% for 50 targets. Against this, the track-only method TSADCNN scored 76.08% and 25.64%, and the signal-statistics-based method scored 77.12% and 29.56%, for 5 and 50 targets, respectively, thus exhibiting a clear advantage for the proposed approach. Full article
(This article belongs to the Section Remote Sensors)
20 pages, 49658 KB  
Article
Dead Chicken Identification Method Based on a Spatial-Temporal Graph Convolution Network
by Jikang Yang, Chuang Ma, Haikun Zheng, Zhenlong Wu, Xiaohuan Chao, Cheng Fang and Boyi Xiao
Animals 2026, 16(3), 368; https://doi.org/10.3390/ani16030368 - 23 Jan 2026
Abstract
In intensive cage rearing systems, accurate dead hen detection remains difficult due to complex environments, severe occlusion, and the high visual similarity between dead hens and live hens in a prone posture. To address these issues, this study proposes a dead hen identification [...] Read more.
In intensive cage rearing systems, accurate dead hen detection remains difficult due to complex environments, severe occlusion, and the high visual similarity between dead hens and live hens in a prone posture. To address these issues, this study proposes a dead hen identification method based on a Spatial-Temporal Graph Convolutional Network (STGCN). Unlike conventional static image-based approaches, the proposed method introduces temporal information to enable dynamic spatial-temporal modeling of hen health states. First, a multimodal fusion algorithm is applied to visible light and thermal infrared images to strengthen multimodal feature representation. Then, an improved YOLOv7-Pose algorithm is used to extract the skeletal keypoints of individual hens, and the ByteTrack algorithm is employed for multi-object tracking. Based on these results, spatial-temporal graph-structured data of hens are constructed by integrating spatial and temporal dimensions. Finally, a spatial-temporal graph convolution model is used to identify dead hens by learning spatial-temporal dependency features from skeleton sequences. Experimental results show that the improved YOLOv7-Pose model achieves an average precision (AP) of 92.8% in keypoint detection. Based on the constructed spatial-temporal graph data, the dead hen identification model reaches an overall classification accuracy of 99.0%, with an accuracy of 98.9% for the dead hen category. These results demonstrate that the proposed method effectively reduces interference caused by feeder occlusion and ambiguous visual features. By using dynamic spatial-temporal information, the method substantially improves robustness and accuracy of dead hen detection in complex cage rearing environments, providing a new technical route for intelligent monitoring of poultry health status. Full article
(This article belongs to the Special Issue Welfare and Behavior of Laying Hens)
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19 pages, 1116 KB  
Article
Automated Pupil Dilation Tracking System Using Computer Vision for Task-Evoked Pupillary Response Analysis: A Low-Cost System Feasibility Study
by Hanna Jasińska and Andrzej Jasinski
Appl. Sci. 2026, 16(3), 1173; https://doi.org/10.3390/app16031173 - 23 Jan 2026
Abstract
This paper presents the design and feasibility evaluation of a low-cost, head-mounted pupil dilation tracking system based on computer vision. The proposed solution employs a standard webcam and active infrared illumination, enabling stable eye image acquisition under controlled lighting conditions. The developed image [...] Read more.
This paper presents the design and feasibility evaluation of a low-cost, head-mounted pupil dilation tracking system based on computer vision. The proposed solution employs a standard webcam and active infrared illumination, enabling stable eye image acquisition under controlled lighting conditions. The developed image processing pipeline incorporates adaptive contrast enhancement and geometric pupil detection, allowing for the estimation of relative changes in pupil diameter in real time. System evaluation was conducted in a controlled experiment involving 24 participants performing an N-back task with emotional modulation, a well-established paradigm for eliciting task-evoked pupillary responses under constant working-memory demands. The results revealed statistically significant changes in relative pupil dilation in response to stimuli with varying emotional valence during a working memory task, confirming the system’s ability to capture task-evoked pupillary responses (TEPRs). The proposed system constitutes a low-cost research tool for studies of task engagement and physiological responses in the context of human–computer interaction and psychophysiology, with a focus on the analysis of functional pupilometric changes. Full article
(This article belongs to the Special Issue Human-Computer Interaction: Advances, Challenges and Opportunities)
20 pages, 7268 KB  
Article
A Two-Dimensional (2-D) Sensor Network Architecture with Artificial Intelligence Models for the Detection of Magnetic Anomalies
by Paolo Gastaldo, Rodolfo Zunino, Alessandro Bellesi, Alessandro Carbone, Marco Gemma and Edoardo Ragusa
Sensors 2026, 26(3), 764; https://doi.org/10.3390/s26030764 (registering DOI) - 23 Jan 2026
Viewed by 25
Abstract
The paper presents the development and preliminary evaluation of a two-dimensional (2-D) network of magnetometers for magnetic anomaly detection. The configuration significantly improves over the existing one-dimensional (1-D) architecture, as it enhances the spatial characterization of magnetic anomalies through the simultaneous acquisition of [...] Read more.
The paper presents the development and preliminary evaluation of a two-dimensional (2-D) network of magnetometers for magnetic anomaly detection. The configuration significantly improves over the existing one-dimensional (1-D) architecture, as it enhances the spatial characterization of magnetic anomalies through the simultaneous acquisition of data over an extended area. This leads to a reliable estimation of the target motion parameters. Each sensor node in the network includes a custom-designed electronic system, integrating a biaxial fluxgate magnetometer that operates in null mode. Deep learning models process the raw measurements collected by the magnetometers and extract structured information that enables both automated detection and preliminary target tracking. In the experimental evaluation, a 5×5 array of nodes was deployed over a 12×12 m2 area for terrestrial tests, using moving ferromagnetic cylinders as targets. The results confirmed the feasibility of the 2-D configuration and supported its integration into intelligent, real-time surveillance systems for security and underwater monitoring applications. Full article
(This article belongs to the Special Issue Feature Papers in Physical Sensors 2025)
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36 pages, 3544 KB  
Article
Distinguishing a Drone from Birds Based on Trajectory Movement and Deep Learning
by Andrii Nesteruk, Valerii Nikitin, Yosyp Albrekht, Łukasz Ścisło, Damian Grela and Paweł Król
Sensors 2026, 26(3), 755; https://doi.org/10.3390/s26030755 (registering DOI) - 23 Jan 2026
Viewed by 56
Abstract
Unmanned aerial vehicles (UAVs) increasingly share low-altitude airspace with birds, making early distinguishing between drones and biological targets critical for safety and security. This work addresses long-range scenarios where objects occupy only a few pixels and appearance-based recognition becomes unreliable. We develop a [...] Read more.
Unmanned aerial vehicles (UAVs) increasingly share low-altitude airspace with birds, making early distinguishing between drones and biological targets critical for safety and security. This work addresses long-range scenarios where objects occupy only a few pixels and appearance-based recognition becomes unreliable. We develop a model-driven simulation pipeline that generates synthetic data with a controlled camera model, atmospheric background and realistic motion of three aerial target types: multicopter, fixed-wing UAV and bird. From these sequences, each track is encoded as a time series of image-plane coordinates and apparent size, and a bidirectional long short-term memory (LSTM) network is trained to classify trajectories as drone-like or bird-like. The model learns characteristic differences in smoothness, turning behavior and velocity fluctuations, and to achieve reliable separation between drone and bird motion patterns on synthetic test data. Motion-trajectory cues alone can support early distinguishing of drones from birds when visual details are scarce, providing a complementary signal to conventional image-based detection. The proposed synthetic data and sequence classification pipeline forms a reproducible testbed that can be extended with real trajectories from radar or video tracking systems and used to prototype and benchmark trajectory-based recognizers for integrated surveillance solutions. The proposed method is designed to generalize naturally to real surveillance systems, as it relies on trajectory-level motion patterns rather than appearance-based features that are sensitive to sensor quality, illumination, or weather conditions. Full article
(This article belongs to the Section Industrial Sensors)
23 pages, 3076 KB  
Review
Water Wastage Management in Deep-Level Gold Mines: The Need for Adaptive Pressure Control
by Waldo T. Gerber, Corne S. L. Schutte, Andries G. S. Gous and Jean H. van Laar
Mining 2026, 6(1), 6; https://doi.org/10.3390/mining6010006 (registering DOI) - 23 Jan 2026
Viewed by 50
Abstract
Water wastage management (WWM) in deep-level mines remains a critical challenge, as wastage increases operational costs and threatens sustainability. This study presents a systematic state-of-the-art review of WWM in deep-level mines. Relevant literature was critically assessed to establish current practices, identify limitations, and [...] Read more.
Water wastage management (WWM) in deep-level mines remains a critical challenge, as wastage increases operational costs and threatens sustainability. This study presents a systematic state-of-the-art review of WWM in deep-level mines. Relevant literature was critically assessed to establish current practices, identify limitations, and explore emerging solutions. Five principal approaches were identified: leak detection and repair, pressure control with fixed schedules, network optimisation, accountability measures, and smart management. While each provides benefits, significant challenges persist. Particularly, current pressure control techniques, essential for limiting leakage, rely on static demand profiles that cannot accommodate the stochastic nature of service water demand, often resulting in over- or under-supply. Smart management systems, which have proven effective for managing stochastic utilities in other industries, present a promising alternative. Enabling technologies such as sensors, automated valves, and tracking systems are already widely deployed in mining, underscoring the technical feasibility of such systems. However, no studies have yet examined their development for WWM in deep-level mines. This study recommends a framework for smart water management tailored to mining conditions and highlights three opportunities: developing real-time demand approximation methods, leveraging occupancy data for demand estimation, and integrating these models with mine water supply control infrastructure for implementation and evaluation. Full article
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25 pages, 3493 KB  
Article
A Human-Centered Visual Cognitive Framework for Traffic Pair Crossing Identification in Human–Machine Teaming
by Bufan Liu, Sun Woh Lye, Terry Liang Khin Teo and Hong Jie Wee
Electronics 2026, 15(2), 477; https://doi.org/10.3390/electronics15020477 - 22 Jan 2026
Viewed by 15
Abstract
Human–machine teaming (HMT) in air traffic management (ATM) promises safer, more efficient operations by combining human expertise in decision-making with machine efficiency in data processing, where traffic pair crossing identification is crucial for effective conflict detection and resolution by recognizing aircraft pairs that [...] Read more.
Human–machine teaming (HMT) in air traffic management (ATM) promises safer, more efficient operations by combining human expertise in decision-making with machine efficiency in data processing, where traffic pair crossing identification is crucial for effective conflict detection and resolution by recognizing aircraft pairs that may lead to conflict. To facilitate this goal, this paper presents a four-phase cognitive framework to enhance HMT for monitoring traffic pairs at crossing points through a human-centered, visual-based approach. The visual cognitive framework integrates three data streams—eye-tracking metrics, mouse-over actions, and issued radar commands—to capture the traffic context from the controller’s perspective. A target pair identification method is designed to generate potential conflict pairs. Controller behavior is then modeled using a sighting timeline, yielding insights to develop the cognitive mechanism. Using air traffic crossing-conflict monitoring in en route airspace as a case study, the framework successfully captures the state of controllers’ monitoring and awareness behavior through tests on five target flight pairs under various crossing conditions. Specifically, aware monitoring activities are characterized by higher fixation count on either flight across a 10 min window, with 53% to 100% of visual input activities occurring between 8 to 7 and 3 to 2 min before crossing, ensuring timely conflict management. Furthermore, the study quantifies the effect of crossing geometry, whereby narrow-angle crossings (21 degrees) require significantly higher monitoring intensity (15 paired sightings) compared to wide or moderate angle crossings. These results indicate that controllers exhibit distinct monitoring and awareness behaviors when identifying and managing conflicts across the different test pairs, demonstrating the effectiveness and applicability of the proposed visual cognitive framework. Full article
13 pages, 1497 KB  
Article
A Spatio-Temporal Model for Intelligent Vehicle Navigation Using Big Data and SparkML LSTM
by Imad El Mallahi, Jamal Riffi, Hamid Tairi, Mostafa El Mallahi and Mohamed Adnane Mahraz
World Electr. Veh. J. 2026, 17(1), 54; https://doi.org/10.3390/wevj17010054 - 22 Jan 2026
Viewed by 11
Abstract
The rapid development of autonomous driving systems has increased the demand for scalable frameworks capable of modeling vehicle motion patterns in complex traffic environments. This paper proposes a big data spatio-temporal modeling architecture that integrates Apache Spark version 4.0.1 (SparkML) with Long Short-Term [...] Read more.
The rapid development of autonomous driving systems has increased the demand for scalable frameworks capable of modeling vehicle motion patterns in complex traffic environments. This paper proposes a big data spatio-temporal modeling architecture that integrates Apache Spark version 4.0.1 (SparkML) with Long Short-Term Memory (LSTM) networks to analyze and classify vehicle trajectory patterns. The proposed SparkML–LSTM framework exploits Spark’s distributed processing capabilities and LSTM’s strength in sequential learning to handle large-scale traffic trajectory data efficiently. Experiments were conducted using the DETRAC dataset, which is a large-scale benchmark for vehicle detection and multi-object tracking consisting of more than 10 h of video captured at 24 different locations. The videos were recorded at 25 frames per second with a resolution of 960 × 540 pixels and annotated across more than 140,000 frames, covering 8.250 vehicles and approximately 1.21 million bounding box annotations. The dataset provides detailed annotations, including vehicle categories (Car, Bus, Van, Others), weather conditions (Sunny, Cloudy, Rainy, Night), occlusion ratio, truncation ratio, and vehicle scale. Based on the extracted trajectory features, vehicle motion patterns were categorized into predefined movement classes derived from trajectory dynamics. The experimental results demonstrate strong classification performance. These findings suggest that the proposed SparkML–LSTM architecture is effective for large-scale spatio-temporal trajectory modeling and traffic behavior analysis, and can serve as a foundation for higher-level decision-making modules in intelligent transportation system. Full article
(This article belongs to the Section Automated and Connected Vehicles)
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24 pages, 2902 KB  
Article
Research on Prolonged Violation Behavior Recognition in Construction Sites Based on Artificial Intelligence
by Kai Yu, Zhenyue Wang, Lujie Zhou, Xuesong Yang, Zhaoxiang Mu and Tianyu Wang
Symmetry 2026, 18(1), 204; https://doi.org/10.3390/sym18010204 - 22 Jan 2026
Viewed by 9
Abstract
Prolonged violation behavior is characterized by sustained temporal presence, slow action changes, and similarity to normal behavior. Due to the complex construction environment, intelligent recognition algorithms face significant challenges. This paper proposes an improved YOLOv8-based model, DGEA-YOLOv8, to address these issues, using “playing [...] Read more.
Prolonged violation behavior is characterized by sustained temporal presence, slow action changes, and similarity to normal behavior. Due to the complex construction environment, intelligent recognition algorithms face significant challenges. This paper proposes an improved YOLOv8-based model, DGEA-YOLOv8, to address these issues, using “playing with mobile phones” as a case study. The model integrates the DCNv3 module in the backbone to enhance behavior deformation adaptability and the GELAN module to improve lightweight performance and global perception in resource-limited environments. An ECA attention mechanism is added to enhance small target detection, while the ASPP module boosts multi-scale perception. ByteTrack is incorporated for continuous tracking of prolonged violation behavior in construction scenarios. Experimental results show that DGEA-YOLOv8 achieves 94.5% mAP50, a 2.95% improvement over the YOLOv8s baseline, with better data capture rates and lower ID change rates compared to algorithms like Deepsort and Strongsort. A construction-specific dataset of over 3000 images verifies the model’s effectiveness. From the perspective of data symmetry, the proposed model demonstrates strong capability in addressing asymmetric feature distributions and behavioral imbalance inherent in prolonged violations, restoring spatiotemporal consistency in detection. In conclusion, DGEA-YOLOv8 provides a precise, efficient, and adaptive solution for recognizing prolonged violation behaviors in construction sites. Full article
(This article belongs to the Section Computer)
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22 pages, 3857 KB  
Article
Trajectory Association for Moving Targets of GNSS-S Radar Based on Statistical and Polarimetric Characteristics Under Low SNR Conditions
by Jiayi Yan, Fuzhan Yue, Zhenghuan Xia, Shichao Jin, Xin Liu, Chuang Zhang, Kang Xing, Zhiying Cui, Zhilong Zhao, Zongqiang Liu, Lichang Duan and Yue Pang
Remote Sens. 2026, 18(2), 367; https://doi.org/10.3390/rs18020367 - 21 Jan 2026
Viewed by 55
Abstract
The Global Navigation Satellite System-Scattering (GNSS-S) radar has a wide coverage and strong concealment, enabling large-scale and long-term monitoring of sea surface targets. However, its signal power is extremely low and susceptible to sea clutter interference. To address the challenge of detecting and [...] Read more.
The Global Navigation Satellite System-Scattering (GNSS-S) radar has a wide coverage and strong concealment, enabling large-scale and long-term monitoring of sea surface targets. However, its signal power is extremely low and susceptible to sea clutter interference. To address the challenge of detecting and tracking moving targets in complex maritime environments using low-resolution radar, this paper proposes a method for extracting moving target trajectories from GNSS-S radar under low signal-to-noise ratio (SNR) conditions. The method constructs a feature plane consisting of statistical and polarization characteristics, based on the unique distribution of different motion targets in this plane, the distinction between sea clutter and multi-motion targets is carried out using machine learning algorithms, and finally the trajectory association of the targets is achieved by the Kalman filter, and the tracking correctness can reach more than 93.89%. Compared with the tracking method based on high-resolution imaging targets, this technique does not require complex imaging operations, and only requires certain processing on the radar echo, which has the advantages of easy operation and high reliability. Full article
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25 pages, 1635 KB  
Review
Advancements in Solar Tracking: A Comprehensive Review of Image-Processing Techniques
by Jihad Rishmany, Chawki Lahoud, Jamal Harmouche, Rodrigue Imad and Nicolas Saba
Sustainability 2026, 18(2), 1117; https://doi.org/10.3390/su18021117 - 21 Jan 2026
Viewed by 85
Abstract
Solar energy is a widely available renewable source suitable for diverse applications, including residential, industrial and aerospace sectors. To maximize energy capture, solar tracking systems adjust panels to maintain perpendicular alignment with sunlight. Various tracking techniques are employed to adjust these trackers, such [...] Read more.
Solar energy is a widely available renewable source suitable for diverse applications, including residential, industrial and aerospace sectors. To maximize energy capture, solar tracking systems adjust panels to maintain perpendicular alignment with sunlight. Various tracking techniques are employed to adjust these trackers, such as sensors, predefined algorithms, deep learning, and image-processing techniques. Image processing-based trackers have gained prominence for their precision and accuracy. This approach uses cameras as sensors to capture real-time sky images and analyze them to detect the sun and its coordinates, orienting solar panels toward its center. This technology can be integrated with other techniques to enhance energy output with high accuracy, minimal tracking error, and low maintenance requirements. This review examines computer vision methods used in solar tracking systems, synthesizing findings from 26 studies published between 2009 and 2024. The paper discusses main system components, methods utilized, and results obtained. Findings demonstrate that the robustness and accuracy of these tracking systems have increased compared to other tracking systems, while tracking error has decreased. Full article
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10 pages, 1063 KB  
Article
Highly Sensitive Hybridization Chain Reaction-Based miRNA Detection Technology Using Diffusivity Analysis of Fluorescent Probe-Modified miRNA Particles
by Momoka Nakai, Yui Watanabe, Maho Koda, Chisato Sakamoto, Tatsuhito Hasegawa, Han-Sheng Chuang and Hiroaki Sakamoto
Sensors 2026, 26(2), 713; https://doi.org/10.3390/s26020713 - 21 Jan 2026
Viewed by 59
Abstract
MicroRNAs (miRNAs) are promising biomarkers for the early detection of various diseases, particularly cancer, driving active development of highly sensitive and selective detection technologies. This study aims to establish a novel miRNA detection technique that utilizes image analysis to track the Brownian motion [...] Read more.
MicroRNAs (miRNAs) are promising biomarkers for the early detection of various diseases, particularly cancer, driving active development of highly sensitive and selective detection technologies. This study aims to establish a novel miRNA detection technique that utilizes image analysis to track the Brownian motion (diffusivity) of fluorescent probe-modified miRNA particles. This method identifies the presence and concentration of miRNAs by exploiting the change in particle size upon hybridization with the target. Furthermore, the use of a probe modified with a photo-crosslinkable artificial nucleic acid (CNV-D) enables the covalent capture of the target miRNA, ensuring high selectivity in biological samples even under stringent washing conditions. By integrating Hybridization Chain Reaction (HCR), the complex size is significantly amplified, dramatically enhancing the detection sensitivity. Consequently, we successfully demonstrated the highly sensitive and specific detection of the cancer biomarker miR-21 in serum, achieving an exceptionally low limit of detection (LOD) of 1 fM. This technology holds great potential to contribute to the early diagnosis of cancer. Full article
(This article belongs to the Special Issue Biomedical Sensors Based on Microfluidics)
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21 pages, 15860 KB  
Article
Robot Object Detection and Tracking Based on Image–Point Cloud Instance Matching
by Hongxing Wang, Rui Zhu, Zelin Ye and Yaxin Li
Sensors 2026, 26(2), 718; https://doi.org/10.3390/s26020718 - 21 Jan 2026
Viewed by 100
Abstract
Effectively fusing the rich semantic information from camera images with the high-precision geometric measurements provided by LiDAR point clouds is a key challenge in mobile robot environmental perception. To address this problem, this paper proposes a highly extensible instance-aware fusion framework designed to [...] Read more.
Effectively fusing the rich semantic information from camera images with the high-precision geometric measurements provided by LiDAR point clouds is a key challenge in mobile robot environmental perception. To address this problem, this paper proposes a highly extensible instance-aware fusion framework designed to achieve efficient alignment and unified modeling of heterogeneous sensory data. The proposed approach adopts a modular processing pipeline. First, semantic instance masks are extracted from RGB images using an instance segmentation network, and a projection mechanism is employed to establish spatial correspondences between image pixels and LiDAR point cloud measurements. Subsequently, three-dimensional bounding boxes are reconstructed through point cloud clustering and geometric fitting, and a reprojection-based validation mechanism is introduced to ensure consistency across modalities. Building upon this representation, the system integrates a data association module with a Kalman filter-based state estimator to form a closed-loop multi-object tracking framework. Experimental results on the KITTI dataset demonstrate that the proposed system achieves strong 2D and 3D detection performance across different difficulty levels. In multi-object tracking evaluation, the method attains a MOTA score of 47.8 and an IDF1 score of 71.93, validating the stability of the association strategy and the continuity of object trajectories in complex scenes. Furthermore, real-world experiments on a mobile computing platform show an average end-to-end latency of only 173.9 ms, while ablation studies further confirm the effectiveness of individual system components. Overall, the proposed framework exhibits strong performance in terms of geometric reconstruction accuracy and tracking robustness, and its lightweight design and low latency satisfy the stringent requirements of practical robotic deployment. Full article
(This article belongs to the Section Sensors and Robotics)
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