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  • Article
  • Open Access
3 Citations
3,257 Views
9 Pages

Racial Differences in the Detection Rate of Bladder Cancer Using Blue Light Cystoscopy: Insights from a Multicenter Registry

  • Seyedeh-Sanam Ladi-Seyedian,
  • Alireza Ghoreifi,
  • Badrinath Konety,
  • Kamal Pohar,
  • Jeffrey M. Holzbeierlein,
  • John Taylor,
  • Max Kates,
  • Brian Willard,
  • Jennifer M. Taylor and
  • Blue Light Cystoscopy with Cysview Registry Group
  • + 7 authors

24 March 2024

The use of blue light cystoscopy (BLC) has been shown to improve bladder tumor detection. However, data demonstrating the efficacy of BLC across different races are limited. Herein, we aim to evaluate heterogeneity in the characteristics of BLC for t...

  • Article
  • Open Access
3 Citations
3,643 Views
10 Pages

1 March 2021

To date, there is only one published report of an outbreak of urinary tract infections by Salmonella species after cystoscopy. Disinfection procedures for cystoscope have come into question. The current study aimed to determine the odds of developing...

  • Article
  • Open Access
21 Citations
9,334 Views
11 Pages

Cystoscopy Accuracy in Detecting Bladder Tumors: A Prospective Video-Confirmed Study

  • Cathrine Silberg Guldhammer,
  • Juan Luis Vásquez,
  • Vibeke Møllegaard Kristensen,
  • Thomas Norus,
  • Naomi Nadler,
  • Jørgen Bjerggaard Jensen and
  • Nessn Azawi

28 December 2023

Background: Bladder cancer ranks as the 10th most common cancer globally. The diagnosis of bladder tumors typically involves cystoscopy. Objective: This study aimed to evaluate the sensitivity and specificity of cystoscopy in detecting bladder tumors...

  • Proceeding Paper
  • Open Access
2,521 Views
8 Pages

Bladder Cancer and Fluorescence Cystoscopy

  • Maria Przygoda and
  • David Aebisher

Bladder cancer is one of the ten most common types of cancer diagnosed in the world. During this time, an unbalanced state of reactive oxygen species’ (ROS) production and antioxidant capacity occurs that causes oxidative damage, cell damage, a...

  • Article
  • Open Access
16 Citations
3,732 Views
7 Pages

Influence of Virtual Reality Devices on Pain and Anxiety in Patients Undergoing Cystoscopy Performed under Local Anaesthesia

  • Mateusz Łuczak,
  • Łukasz Nowak,
  • Joanna Chorbińska,
  • Katarzyna Galik,
  • Paweł Kiełb,
  • Jan Łaszkiewicz,
  • Andrzej Tukiendorf,
  • Katarzyna Kościelska-Kasprzak,
  • Bartosz Małkiewicz and
  • Wojciech Krajewski
  • + 2 authors

16 November 2021

Background: Bladder cancer is one of the most common malignancies. Its diagnosis is based on transurethral cystoscopy. Virtual reality (VR) is a three-dimensional world generated through the projection of images, the emission of sounds and other stim...

  • Article
  • Open Access
2 Citations
5,208 Views
8 Pages

D-Mannose Plus Saccharomyces boulardii to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study

  • Carmelo Quattrone,
  • Celeste Manfredi,
  • Luigi Napolitano,
  • Angelo Ferraro,
  • Concetta Distefano,
  • Antonio Di Girolamo,
  • Carmine Sciorio,
  • Vittorio Imperatore,
  • Francesco Bottone and
  • Lorenzo Spirito
  • + 3 authors

17 June 2023

Background and Objectives: Patients undergoing cystoscopy can experience discomfort or pain during the procedure. In some cases, a urinary tract infection (UTI) with storage lower urinary tract symptoms (LUTS) may occur in the days following the proc...

  • Article
  • Open Access
1 Citations
1,824 Views
9 Pages

The Role of Bladder-Washing Cytology as an Adjunctive Method to Cystoscopy During Follow-Up for Low-Grade TaT1 Non-Muscle-Invasive Bladder Cancer

  • Enric Carbonell,
  • Clàudia Mercader,
  • Héctor Alfambra,
  • Paulette Narvaez,
  • Eric Villalba,
  • Rita Pagès,
  • Ignacio Asiain,
  • Meritxell Costa,
  • Agustín Franco and
  • Antoni Vilaseca
  • + 2 authors

1 November 2024

Background and Objective: The role of urine cytology during follow-up for low-grade (LG) non-muscle-invasive bladder cancer (NMIBC) is not well established, although cytology has low sensitivity in detecting LG recurrences. Our study aims to evaluate...

  • Systematic Review
  • Open Access
68 Citations
8,621 Views
15 Pages

Performance of Narrow Band Imaging (NBI) and Photodynamic Diagnosis (PDD) Fluorescence Imaging Compared to White Light Cystoscopy (WLC) in Detecting Non-Muscle Invasive Bladder Cancer: A Systematic Review and Lesion-Level Diagnostic Meta-Analysis

  • Giorgio I. Russo,
  • Tamir N. Sholklapper,
  • Andrea Cocci,
  • Giuseppe Broggi,
  • Rosario Caltabiano,
  • Angela B. Smith,
  • Yair Lotan,
  • Giuseppe Morgia,
  • Ashish M. Kamat and
  • Giovanni E. Cacciamani
  • + 4 authors

30 August 2021

Despite early detection and regular surveillance of non-muscle invasive bladder cancer (NMIBC), recurrence and progression rates remain exceedingly high for this highly prevalent malignancy. Limited visualization of malignant lesions with standard cy...

  • Article
  • Open Access
3 Citations
2,070 Views
9 Pages

Evaluation of the Diagnostic Efficacy of the AI-Based Software INF-M01 in Detecting Suspicious Areas of Bladder Cancer Using Cystoscopy Images

  • Jongchan Kim,
  • Won Sik Ham,
  • Kyo Chul Koo,
  • Jongsoo Lee,
  • Hyun Kyu Ahn,
  • Jae Yong Jeong,
  • Sang Yeop Baek,
  • Su Jin Lee and
  • Kwang Suk Lee

24 November 2024

Background/Objectives: We aimed to evaluate the accuracy of the artificial intelligence (AI)-based software INF-M01 in diagnosing suspected bladder tumors using cystoscopy images. Additionally, we aimed to assess the ability of INF-M01 to distinguish...

  • Article
  • Open Access
2 Citations
2,164 Views
22 Pages

24 April 2024

White light cystoscopy is the gold standard for the diagnosis of bladder cancer. Automatic and accurate tumor detection is essential to improve the surgical resection of bladder cancer and reduce tumor recurrence. At present, Transformer-based medica...

  • Article
  • Open Access
15 Citations
3,159 Views
8 Pages

Surveillance of Low-Grade Non-Muscle Invasive Bladder Tumors Using Uromonitor: SOLUSION Trial

  • Nessn Azawi,
  • Juan Luis Vásquez,
  • Thomas Dreyer,
  • Cathrine Silberg Guldhammer,
  • Rami Muthanna Saber Al-Juboori,
  • Anna Munk Nielsen and
  • Jørgen Bjerggaard Jensen

17 April 2023

Background: The surveillance of non-muscle invasive bladder cancer (NMIBC) requires frequent cystoscopies, which are costly and uncomfortable for patients. Uromonitor is a validated non-invasive urinary test for detecting NMIBC recurrence. However, d...

  • Article
  • Open Access
4 Citations
3,489 Views
16 Pages

Xpert Bladder Cancer Monitor for the Early Detection of Non-Muscle Invasive Bladder Cancer Recurrences: Could Cystoscopy Be Substituted?

  • Fernando Lozano,
  • Carles X. Raventós,
  • Albert Carrion,
  • Carme Dinarés,
  • Javier Hernández,
  • Enrique Trilla and
  • Juan Morote

19 July 2023

XBM was prospectively assessed in spontaneous urine collected just before flexible cystoscopy and washing cytology carried out within the first 2 years follow-up of 337 patients with NMIBC. Recurrences were pathologically confirmed in 49 patients (14...

  • Article
  • Open Access
9 Citations
6,366 Views
8 Pages

(1) Background: Limited data showed changes in glomerulation in the bladder mucosa of patients with interstitial cystitis (IC) after intravesical hyaluronic acid (HA) bladder infusion. We aimed to investigate the above changes. (2) Methods: Medical r...

  • Article
  • Open Access
329 Views
10 Pages

Background/Objectives: Low-risk non-muscle-invasive bladder cancer (NMIBC) is associated with extremely low rates of progression and cancer-specific mortality. Current surveillance strategies recommend yearly cystoscopic surveillance after the initia...

  • Article
  • Open Access
12 Citations
4,417 Views
15 Pages

The Role of New Technologies in the Diagnosis and Surveillance of Non-Muscle Invasive Bladder Carcinoma: A Prospective, Double-Blinded, Monocentric Study of the XPERT© Bladder Cancer Monitor and Narrow Band Imaging© Cystoscopy

  • Gad Singer,
  • Venkat M. Ramakrishnan,
  • Uwe Rogel,
  • Andreas Schötzau,
  • Daniel Disteldorf,
  • Philipp Maletzki,
  • Jean-Pascal Adank,
  • Marc Hofmann,
  • Tilo Niemann and
  • Lukas J. Hefermehl
  • + 3 authors

26 January 2022

Follow-up is essential for the early detection of recurrent non-muscle invasive bladder cancers (NMIBC). This study investigates the clinical relevance of new diagnostic tools such as an mRNA-based urine test (XPERT© Bladder Cancer Monitor, XBCM...

  • Article
  • Open Access
419 Views
13 Pages

The GreenBladder Study: Early Detection of Bladder Cancer in Greenland Using a Urinary Biomarker

  • Nathalie Demuth Fryd,
  • Nadja Albertsen,
  • Simon Bernth-Andersen,
  • Andreas Ernst and
  • Jørgen Bjerggaard Jensen

16 January 2026

Background: Bladder cancer (BC) incidence in Greenland is lower than in other Nordic countries, yet mortality is disproportionately high, suggesting delayed detection. Cystoscopy is the diagnostic gold standard to detect BC, but access in Greenland i...

  • Article
  • Open Access
7 Citations
2,520 Views
9 Pages

27 August 2021

Bladder cancer has a high recurrence rate; therefore, frequent and effective monitoring is essential for disease management. Cystoscopy is considered the gold standard for the diagnosis and continuous monitoring of bladder cancer. However, cystoscopy...

  • Review
  • Open Access
2 Citations
1,548 Views
21 Pages

Beyond Visualization: Advanced Imaging, Theragnostics and Biomarker Integration in Urothelial Bladder Cancer

  • Eduardo Albers Acosta,
  • Lira Pelari Mici,
  • Carlos Márquez Güemez,
  • Clara Velasco Balanza,
  • Manuel Saavedra Centeno,
  • Marta Pérez Pérez,
  • Guillermo Celada Luis,
  • Cristina Quicios Dorado,
  • José Daniel Subiela and
  • Luis San José Manso
  • + 3 authors

8 October 2025

Background/Objectives: Bladder cancer is characterized by high recurrence and progression rates, posing a challenge to current diagnostic and treatment strategies. This review aims to provide a comprehensive overview of emerging technologies, includi...

  • Article
  • Open Access
43 Citations
5,177 Views
11 Pages

Clinical Validation of a Urine Test (Uromonitor-V2®) for the Surveillance of Non-Muscle-Invasive Bladder Cancer Patients

  • Caroline A. Sieverink,
  • Rui P. M. Batista,
  • Hugo J. M. Prazeres,
  • João Vinagre,
  • Cristina Sampaio,
  • Ricardo R. Leão,
  • Valdemar Máximo,
  • J. Alfred Witjes and
  • Paula Soares

24 September 2020

The costly and burdensome nature of the current follow-up methods in non-muscle-invasive bladder cancer (NMIBC) drives the development of new methods that may alternate with regular cystoscopy and urine cytology. The Uromonitor-V2® is a new urine...

  • Article
  • Open Access
1 Citations
820 Views
19 Pages

Diagnostic and Prognostic Implications of FGFR3, TP53 Mutation and Urinary Biomarkers in Urothelial Carcinoma in Pakistani Cohort

  • Muhammad Asif,
  • Faiza Abdul Rashid,
  • Saima Shakil Malik,
  • Dilshad Ahmed Khan,
  • Muhammad Tanveer Sajid,
  • Asma Gul and
  • Muhammad Tahir Khadim

1 December 2025

Background: Urothelial carcinoma (UC) presents with clinically heterogeneous disease. There is an emerging need to explore the prognosis of non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). Therefore, we aimed to e...

  • Article
  • Open Access
511 Views
10 Pages

Updated Analysis: Blue-Light Transurethral Resection and Biopsy of Bladder Cancer with Hexaminolevulinate in a Single UK Centre

  • Anushree Kucheria,
  • Elaina Gubbay,
  • Aoife Meabh Linzell,
  • Irfan Kar,
  • Mohammad Alomari,
  • Kimberley Chan,
  • Christine Gan and
  • Nikhil Vasdev

2 February 2026

Objective: To evaluate the diagnostic yield of blue-light cystoscopy (BLC) compared with white-light cystoscopy (WLC) in detecting carcinoma in situ (CIS) and muscle-invasive bladder cancer (MIBC), and to assess recurrence-free survival (RFS) followi...

  • Article
  • Open Access
9 Citations
4,127 Views
12 Pages

Artificial Intelligence-Based Classification and Segmentation of Bladder Cancer in Cystoscope Images

  • Won Ku Hwang,
  • Seon Beom Jo,
  • Da Eun Han,
  • Sun Tae Ahn,
  • Mi Mi Oh,
  • Hong Seok Park,
  • Du Geon Moon,
  • Insung Choi,
  • Zepa Yang and
  • Jong Wook Kim

28 December 2024

Background/Objectives: Cystoscopy is necessary for diagnosing bladder cancer, but it has limitations in identifying ambiguous lesions, such as carcinoma in situ (CIS), which leads to a high recurrence rate of bladder cancer. With the significant adva...

  • Case Report
  • Open Access
1,647 Views
13 Pages

A Literature Review of Phantom Bladder Perforation: The Curious Case of Bladder Lipoma

  • Surina Patel,
  • Mehreet Kaur Chahal,
  • Scott Durham,
  • Haitham Elsamaloty and
  • Puneet Sindhwani

1 August 2025

Introduction: Although lipomas are common benign tumors found in adults, lipomas of the bladder are extremely rare. Bladder lipomas are infrequently reported in the urologic literature, with only 19 cases published worldwide. These can present as a m...

  • Review
  • Open Access
24 Citations
6,105 Views
19 Pages

Biomarkers for Precision Urothelial Carcinoma Diagnosis: Current Approaches and the Application of Single-Cell Technologies

  • Michelle Hong,
  • George He,
  • Siting Goh,
  • Alvin Wei Xiang Low,
  • Kae Jack Tay,
  • Tony Kiat Hon Lim,
  • Joe Yeong,
  • Li Yan Khor and
  • Tong Seng Lim

12 January 2021

Urothelial carcinoma (UC) is the most frequent malignancy of the urinary system and is ranked the sixth most diagnosed cancer in men worldwide. Around 70–75% of newly diagnosed UC manifests as the non-muscle invasive bladder cancer (NMIBC) subt...

  • Article
  • Open Access
14 Citations
2,703 Views
18 Pages

17 November 2022

Bladder cancer is a common and often fatal disease. Papillary bladder tumors are well detectable using cystoscopic imaging, but small or flat lesions are frequently overlooked by urologists. However, detection accuracy can be improved if the images f...

  • Article
  • Open Access
3 Citations
2,721 Views
10 Pages

A High-Efficiency Consultation Improves Urological Diagnosis in Patients with Complex LUTS—A Pilot Study

  • Alexandru Ciudin,
  • Bernat Padulles,
  • Pasqualino Manasia,
  • Josep Alcoberro,
  • Sanae Ounia,
  • Maria Lopez,
  • Natalia Allue,
  • Joan Maria Ferrer,
  • Jaume Duran and
  • Antonio Aguilar

(1) Background: The diagnosis of moderate-severe lower urinary tract symptoms (LUTS) is not easy due to the complexity of the micturition act. Sequential diagnostic tests can be time consuming due to waiting lists. Thus, we developed a diagnostic mod...

  • Review
  • Open Access
7 Citations
9,862 Views
54 Pages

Bladder Cancer Basic Study and Current Clinical Trials

  • Dominik Godlewski,
  • Sara Czech,
  • Dorota Bartusik-Aebisher and
  • David Aebisher

22 September 2024

Bladder cancer (BCa) is the fourth most common cancer in men and one of the most common urinary tract cancers, especially in developed countries. The aim of this paper is to comprehensively analyze the biology of bladder cancer, including its epidemi...

  • Article
  • Open Access
1 Citations
1,305 Views
26 Pages

15 November 2024

The automatic and accurate segmentation of bladder tumors is a key step in assisting urologists in diagnosis and analysis. At present, existing Transformer-based methods have limited ability to restore local detail features and insufficient boundary...

  • Article
  • Open Access
1,006 Views
9 Pages

25 November 2025

Background/Objectives: Reconstruction of membranous urethral strictures poses significant surgical challenges, including risks of urinary incontinence and erectile dysfunction. Optilume drug-coated balloon dilation (DCBD) is a minimally invasive trea...

  • Article
  • Open Access
3 Citations
3,465 Views
9 Pages

Optilume Drug-Coated Balloon for Acute Urinary Retention After Failed Treatment for Complex Recurrent Urethral Stricture Disease

  • Lukas Andrius Jelisejevas,
  • Peter Rehder,
  • Jannik Wassermann,
  • Patricia Kink and
  • Gennadi Tulchiner

11 April 2025

Background and Objectives: We aimed to assess the outcomes of upfront Optilume drug-coated balloon (DCB) dilation in patients after failed treatment for complex recurrent urethral stricture disease. All patients presented with acute urinary retention...

  • Article
  • Open Access
587 Views
9 Pages

The Clinical Integration of ChatGPT Through an Augmented Patient Encounter in a Real-World Urological Cohort: A Feasibility Study

  • Shane Qin,
  • Emre Alpay,
  • Bodie Chislett,
  • Joseph Ischia,
  • Luke Gibson,
  • Damien Bolton and
  • Dixon T. S. Woon

Background/Objectives: To evaluate the viability of using ChatGPT in a real clinical environment for patient education during informed consent for flexible cystoscopy, assessing its practicality, patient perceptions, and clinician evaluations within...

  • Review
  • Open Access
531 Views
6 Pages

Clinical Utility of Bladder Cancer Biomarkers

  • Laura Maria Krabbe,
  • Georgios Gakis and
  • Yair Lotan

13 October 2020

Each year, there are an estimated 550 000 diagnoses of bladder cancer worldwide, and almost 200 000 deaths from bladder cancer. The need for frequent follow-up, including invasive procedures like cystoscopy, repetitive procedures like transurethral r...

  • Article
  • Open Access
12 Citations
6,059 Views
13 Pages

Antimicrobial Prophylaxis for Urologic Procedures in Paediatric Patients: A RAND/UCLA Appropriateness Method Consensus Study in Italy

  • Susanna Esposito,
  • Erika Rigotti,
  • Alberto Argentiero,
  • Caterina Caminiti,
  • Elio Castagnola,
  • Laura Lancella,
  • Elisabetta Venturini,
  • Maia De Luca,
  • Stefania La Grutta and
  • The Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group
  • + 7 authors

23 February 2022

The main aim of surgical antimicrobial prophylaxis (SAP) in urologic procedures is to prevent bacteraemia, surgical site infections (SSIs), and postoperative urinary tract infections (ppUTIs). Guidelines for SAP in paediatric urology are lacking. Onl...

  • Systematic Review
  • Open Access
3 Citations
3,906 Views
14 Pages

Active Surveillance in Non-Muscle Invasive Bladder Cancer: A Systematic Review

  • Míriam Campistol,
  • Fernando Lozano,
  • Albert Carrion,
  • Carles Xavier Raventós,
  • Juan Morote and
  • Enrique Trilla

20 May 2025

Bladder cancer is the ninth most common cancer globally, with most cases classified as non-muscle-invasive bladder cancer (NMIBC). While transurethral resection of the bladder tumor (TURBT) remains the gold-standard treatment, its complications, high...

  • Case Report
  • Open Access
720 Views
10 Pages

Clinical Experience with URO17® in the Diagnosis and Surveillance of Bladder Cancer

  • Shahram Shawn Gholami,
  • Mehran Movassaghi,
  • Sasha Homayoun and
  • Nikhil Vasdev

16 November 2025

Objective: To describe the clinical use of URO17®, a noninvasive, urine-based immunocytochemistry assay targeting Keratin 17 (K17), as an adjunct to conventional diagnostic methods for urothelial carcinoma. Materials and Methods: These illustrati...

  • Systematic Review
  • Open Access
3 Citations
2,766 Views
11 Pages

Confocal Laser Endomicroscopy for Bladder Cancer Detection: Where Do We Stand?

  • Angelo Naselli,
  • Andrea Guarneri and
  • Giacomo Maria Pirola

5 October 2022

Introduction: Confocal laser endomicroscopy (CLE) is a relatively new technology that allows for a real-time in situ microscopic characterization of tissue lesions, being able to discriminate between low- and high-grade ones. After a first period of...

  • Systematic Review
  • Open Access
8 Citations
4,135 Views
20 Pages

Active Surveillance in Non-Muscle Invasive Bladder Cancer, the Potential Role of Biomarkers: A Systematic Review

  • Diego Parrao,
  • Nemecio Lizana,
  • Catalina Saavedra,
  • Matías Larrañaga,
  • Carolina B. Lindsay,
  • Ignacio F. San Francisco and
  • Juan Cristóbal Bravo

12 April 2024

Bladder cancer (BC) is the tenth most common cause of cancer worldwide and is the thirteenth leading cause of cancer mortality. The non-muscle invasive (NMI) variant represents 75% of cases and has a mortality rate of less than 1%; however, it has a...

  • Review
  • Open Access
1 Citations
2,511 Views
13 Pages

The Management of Non-Muscle-Invasive Bladder Cancer in a Veteran Patient Population: Issues and Recommendations

  • Jennifer Taylor,
  • Sagar Patel,
  • Krishnanath Gaitonde,
  • Kirsten Greene,
  • Joseph C. Liao,
  • Glen McWilliams,
  • Mark Sawyer,
  • Florian Schroeck,
  • Aly Alrabaa and
  • Jeffrey Jones
  • + 2 authors

28 October 2024

The ability of the Veterans Health Administration System to care for veterans with bladder cancer is influenced by the increased complexity of both veterans and the system’s capacity to do so, which is determined by personnel and equipment allo...

  • Feature Paper
  • Review
  • Open Access
3 Citations
11,957 Views
21 Pages

Sex Determination in Reptiles: A Review

  • Alessandro Vetere,
  • Michele Capasso and
  • Francesco Di Ianni

10 January 2025

Reptile biodiversity is rapidly declining, with over 11,733 recognized species across 1226 genera being documented, many of which are endangered. Captive breeding programs play a crucial role in conservation; however, effective management requires ac...

  • Article
  • Open Access
6 Citations
2,502 Views
9 Pages

Clinical Utility of Oncuria™, a Multiplexed Liquid Biopsy for the Non-Invasive Detection of Bladder Cancer—A Pilot Study

  • Kaoru Murakami,
  • Ian Pagano,
  • Hideki Furuya,
  • Timothy Daskivich,
  • Dave Mori and
  • Charles J. Rosser

Oncuria™ is a validated quantitative multiplex immunoassay capable of detecting bladder cancer from a voided urine sample. Herein, we sought to determine whether Oncuria™ affects physicians’ use of non-invasive and invasive diagnost...

  • Article
  • Open Access
1,182 Views
12 Pages

Background/Objectives: In non-muscle-invasive bladder cancer (NMIBC), the decision for immediate postoperative single-dose intravesical chemotherapy (SI) is based on clinical and presumed pathological features, as a definitive pathology is unknown at...

  • Review
  • Open Access
28 Citations
4,822 Views
17 Pages

Bladder Epicheck Test: A Novel Tool to Support Urothelial Carcinoma Diagnosis in Urine Samples

  • Vincenzo Fiorentino,
  • Cristina Pizzimenti,
  • Mariausilia Franchina,
  • Esther Diana Rossi,
  • Pietro Tralongo,
  • Angela Carlino,
  • Luigi Maria Larocca,
  • Maurizio Martini,
  • Guido Fadda and
  • Francesco Pierconti

6 August 2023

Bladder cancer and upper urothelial tract carcinoma are common diseases with a high risk of recurrence, thus necessitating follow-up after initial treatment. The management of non-muscle invasive bladder carcinoma (NMIBC) after transurethral resectio...

  • Article
  • Open Access
7 Citations
2,767 Views
13 Pages

Rapid Detection of Recurrent Non-Muscle Invasive Bladder Cancer in Urine Using ATR-FTIR Technology

  • Abdullah I. El-Falouji,
  • Dalia M. Sabri,
  • Naira M. Lotfi,
  • Doaa M. Medany,
  • Samar A. Mohamed,
  • Mai Alaa-eldin,
  • Amr Mounir Selim,
  • Asmaa A. El Leithy,
  • Haitham Kalil and
  • Ahmed Mohamed
  • + 1 author

14 December 2022

Non-muscle Invasive Bladder Cancer (NMIBC) accounts for 80% of all bladder cancers. Although it is mostly low-grade tumors, its high recurrence rate necessitates three-times-monthly follow-ups and cystoscopy examinations to detect and prevent its pro...

  • Article
  • Open Access
8 Citations
3,486 Views
12 Pages

Accurate Detection of Urothelial Bladder Cancer Using Targeted Deep Sequencing of Urine DNA

  • Dongin Lee,
  • Wookjae Lee,
  • Hwang-Phill Kim,
  • Myong Kim,
  • Hyun Kyu Ahn,
  • Duhee Bang and
  • Kwang Hyun Kim

22 May 2023

Patients with hematuria are commonly given an invasive cystoscopy test to detect bladder cancer (BC). To avoid the risks associated with cystoscopy, several urine-based methods for BC detection have been developed, the most prominent of which is the...

  • Article
  • Open Access
4 Citations
2,857 Views
13 Pages

Use of Multiple Machine Learning Approaches for Selecting Urothelial Cancer-Specific DNA Methylation Biomarkers in Urine

  • Christina U. Köhler,
  • Karin Schork,
  • Michael Turewicz,
  • Martin Eisenacher,
  • Florian Roghmann,
  • Joachim Noldus,
  • Katrin Marcus,
  • Thomas Brüning and
  • Heiko U. Käfferlein

Diagnosing urothelial cancer (UCa) via invasive cystoscopy is painful, specifically in men, and can cause infection and bleeding. Because the UCa risk is higher for male patients, urinary non-invasive UCa biomarkers are highly desired to stratify men...

  • Review
  • Open Access
6 Citations
4,487 Views
15 Pages

Applications of Exosomes in Diagnosing Muscle Invasive Bladder Cancer

  • Jillian Marie Walker,
  • Padraic O’Malley and
  • Mei He

23 September 2022

Muscle Invasive Bladder Cancer (MIBC) is a subset of bladder cancer with a significant risk for metastases and death. It accounts for nearly 25% of bladder cancer diagnoses. A diagnostic work-up for MIBC is inclusive of urologic evaluation, radiograp...

  • Review
  • Open Access
1 Citations
3,606 Views
15 Pages

Partial Cystectomy for Muscle-Invasive Bladder Cancer

  • Peter S. Palencia,
  • Nethusan Sivanesan,
  • Syed Rahman,
  • Fady Ghali,
  • David Hesse,
  • John Colberg,
  • Ashwin Sridhar,
  • John D. Kelly,
  • Byron H. Lee and
  • Wei-Shen Tan
  • + 1 author

3 August 2025

Partial cystectomy is a surgical bladder-sparing option for selected patients with muscle-invasive bladder cancer (MIBC), urachal adenocarcinoma and diverticular bladder tumors. Partial cystectomy hold several advantages. It allows for definite patho...

  • Review
  • Open Access
29 Citations
6,159 Views
23 Pages

Noninvasive Urine-Based Tests to Diagnose or Detect Recurrence of Bladder Cancer

  • Marine Charpentier,
  • Charly Gutierrez,
  • Thierry Guillaudeux,
  • Grégory Verhoest and
  • Rémy Pedeux

1 April 2021

Liquid biopsies are increasingly used for the diagnosis and follow-up of cancer patients. Urine is a body fluid that can be used to detect cancers and others diseases. It is noninvasive and easy to collect. To detect Bladder Cancer (BC), cytology is...

  • Article
  • Open Access
10 Citations
3,267 Views
9 Pages

3 July 2022

Urothelial bladder cancer is a heterogeneous disease and one of the most common cancers worldwide. Bladder cancer ranges from low-grade tumors that recur and require long-term invasive surveillance to high-grade tumors with high mortality. After the...

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