Search Results (76)

Background and Clinical Significance: Endobronchial leiomyoma is a rare benign tumor of the respiratory tract, accounting for less than 2% of all benign pulmonary neoplasms. Most cases have been treated surgically or with endoscopic modalities such as laser or rigid bronchoscopy-assisted cryotherapy. Flexible bronchoscopic cryoextraction has been rarely reported, typically with 2.2-mm probes. Small-caliber cryoprobes (1.1- and 1.7-mm) have been validated for diagnostic transbronchial cryobiopsy but not for therapeutic removal of leiomyoma. We report a case of complete removal of endobronchial leiomyoma using a 1.7-mm cryoprobe via flexible bronchoscopy, demonstrating full airway and physiologic recovery. Case Presentation: A 25-year-old never-smoking man was referred after an abnormal health-screening chest radiograph demonstrated right middle and lower lobe atelectasis. Chest CT revealed a mass obstructing the proximal bronchus intermedius. Spirometry showed reduced FEV₁ and FVC with preserved FEV₁/FVC ratio, consistent with central airway obstruction. Therapeutic flexible bronchoscopy (Olympus BF-1TQ290) was performed under endotracheal intubation. Initial forceps biopsies were followed by transbronchial cryobiopsy with a 1.7-mm cryoprobe, applied for five freeze–adhesion cycles. The mass detached en bloc and was retrieved without complications, resulting in complete airway recanalization and visualization of the right middle and lower lobe bronchi. Histopathology showed interlacing fascicles of bland spindle cells with cigar-shaped nuclei, positive for SMA and desmin and negative for S-100 and CD34, confirming leiomyoma. The patient was discharged the next day. At one-year follow-up, bronchoscopy and CT demonstrated no recurrence, and spirometry normalized. Conclusions: Reports combining flexible bronchoscopy with a 1.7-mm small-caliber cryoprobe for en bloc removal of endobronchial leiomyoma are rare. This technique may represent a minimally invasive option for selected cases, provided careful hemostatic planning and appropriate case selection. Full article

Social media promotion of harmful products (e.g., combustible tobacco) poses a public health threat. However, strategies that amplify exposure to and engagement with such content remain understudied. This study aims to characterize strategies boosting cigar, little cigar, and cigarillo (CLCC) marketing visibility, referrals, and engagement on Instagram. Using keyword rules, we collected publicly available CLCC-related Instagram posts from CrowdTangle for a six-year period from August 2016 to October 2021. Posts were categorized as commercial (e.g., posts by tobacco brands or vendors) or organic and were coded for consumer engagement (CE) strategies (e.g., presence of prompts to like/share) using a combination of machine learning methods and human coding. Temporal engagement trends were analyzed using metadata. A total of 320,488 CLCC-related public posts were collected, with 44.6% (n = 142,875) identified as overtly commercial. Of these, 33.5% (n = 47,832) contained CE cues, including discounts and giveaways for tagging peers, liking, commenting, or following CLCC brands and spokesperson/influencers accounts, as well as calls to participate in contests and polls. Overtly commercial CE messages consistently garnered more comments per post and likes per post than non-CE commercial posts. There was a significant upward trend in the rate of comments on CE posts, suggesting growing effectiveness in eliciting user interaction. The proliferation of and high level of engagement with cigar-related promotional messages on Instagram demonstrate the need for public health surveillance and regulation of the evolving strategies promoting CLCC marketing exposure, reach, and engagement on social media. Full article

The Fermi condensation flows in the sine-Gordon–Thirring model with two impurities coupling are investigated in this paper; these matter flows can be induced by the Ricci flow perturbation in the two-dimensional string $\sigma$ model. The Ricci flow perturbation equations are derived according to the Gauss–Codazzi equations, and the two-loop asymptotic perturbation solution of the cigar soliton is reduced by using a small parameter expansion method. Moreover, the thermodynamic quantities on the cigar soliton background are obtained by using the variational functional integrals method. Subsequently, the Fermi condensation flows varying with the momentum scale $\lambda$ are analyzed and discussed. We find that the energy density, the correlation function, and the condensation fluctuations will decrease, but the entropy will increase monotonically. The Fermi condensed matter can maintain thermodynamic stability under the Ricci flow perturbation. Full article

This work studies the water-exit problems of slender cylinders under various conditions through experimental investigation. An experimental platform was equipped with high-speed photography. A total of 13 experimental cases with varying head shapes (conical, spherical, and truncated cone designs), length-to-diameter ratios (5:1–7:1), ejection velocities (7.24–17.93 m/s), and elastic moduli (227.36–279.14 MPa) were conducted to capture water-exit characteristics. The investigation identified ejection velocity as the predominant parameter governing cavity morphology and stability, with higher velocities correlating to increased cavity dimensions and reduced drag coefficients by 54%. Conical head shape resulted in superior drag reduction characteristics, forming a typical cigar-shaped cavity with clear and regular boundaries. Additionally, an increased length-to-diameter ratio substantially improved drag reduction performance by 33%. Material elastic moduli proved crucial for water-exit stability, as cylinders with lower moduli experienced severe bending deformation and even trajectory changes, while higher moduli cylinders maintained their form with minimal deformation. This study illuminates the physical mechanisms of slender body water-exit under multi-factor coupling conditions, providing experimental evidence and theoretical guidance for cross-media vehicle design and underwater equipment optimization. Full article

Bacteria are ubiquitous in the environment and critical to human health and disease, yet only a small fraction can be identified through standard culture methods. Advances in next-generation sequencing techniques have improved bacterial identification, but these DNA-based methods cannot distinguish live bacteria from relic DNA. Recently, DNA-labeling dyes (e.g., 5-bromo-2′-deoxyuridine [BrdU] and propidium monoazide [PMA]) have been used to detect metabolically active bacteria in different sample types. Here, we compare BrdU and PMA in combination with 16SrRNA gene sequencing to characterize metabolically active bacteria in two different sample types: (1) manufactured products (n = 78; cigarettes, hookah, and little cigar) and (2) natural samples (n = 186; rainwater, soil, and produce). Metabolically active bacterial communities identified in BrdU-labeled samples had lower alpha diversity than that of PMA-treated and non-treated samples. Pseudomonas, Sphingomonas, Enterobacter, and Acinetobacter were observed in all the samples tested. Irrespective of sample type, Pseudomonas was predominant in BrdU-treated samples, while Acinetobacter was more abundant in non-treated samples compared to PMA-treated samples. We also observed that PMA-treated samples tend to overestimate the metabolically active bacterial fraction compared to BrdU-treated samples. Overall, our study highlights how different labeling techniques influence bacterial community analysis findings, underscoring the need for careful selection of labeling approaches when assessing environmental samples. Full article

Background: Cigar smoking poses significant public health challenges due to its rising prevalence and associated health risks. However, research on cigar use in China remains limited. This study investigates the prevalence, demographic characteristics, and key factors associated with cigar use among Chinese adults. Methods: We analyzed data from the 2018–2019 China Health Literacy Survey, including 86,701 participants aged 20–69 years. Multistage stratified sampling was employed, and logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for factors associated with cigar use. Weighted data were applied to ensure national representation. Results: Of the 86,701 respondents, 1025 participants reported having used cigars, including 248 exclusive cigar users and 777 dual users of cigars and other tobacco products. Cigar use was significantly higher among men (1.93%) than women (0.05%). Most users were aged 50–59, with a mean age of 49.3 years. Factors associated with cigar use among men included higher education (for college and higher, OR: 1.81; 95% CI: 1.42–2.30), lower household income (for income < 20,000, OR: 1.02; 95% CI: 1.08–1.53), poor self-reported health (OR: 1.45; 95% CI: 1.15–1.83), and severe nicotine dependence (FTND ≥ 7 points, OR: 2.09, 95% CI: 1.67–2.61). Cigar use prevalence showed notable regional variation, with the highest rates observed in northern and eastern provinces. Interpretation: The estimated number of cigar users in China is approximately 10.46 million. Male cigar users often represent a unique demographic: “knowledgeable but economically marginalized” individuals, characterized by higher education but lower economic status. Tailored tobacco control measures addressing regional disparities, socioeconomic factors, and marketing-driven misconceptions about cigars are essential to reduce public health impacts. Full article

Lettuce (Lactuca sativa L.) plants showing leaf curl and vein enation symptoms were found in Yunnan province, China. PCR detection with genus-specific primers revealed that symptomatic lettuce plants were infected with Begomovirus. The full-length viral component and satellite molecules were obtained by RCA, restriction enzyme digestion, PCR, cloning and DNA sequencing. A viral component (YN-2023-WJ) and three satellite molecules (YN-2023-WJ-alpha1, YN-2023-WJ-alpha2 and YN-2023-WJ-beta) were obtained from diseased lettuce plants. YN-2023-WJ exhibited the highest nt identity at 97.1% with pepper leaf curl Yunnan virus isolated from cigar plants. YN-2023-WJ-beta displayed the highest nt identity at 93.9% with tomato leaf curl China betasatellite. YN-2023-WJ-alpha1 showed the highest nt identity at 94.7% with ageratum yellow vein alphasatellite. YN-2023-WJ-alpha2 shared the highest nt identity at 75.6% with gossypium mustelinum symptomless alphasatellite and vernonia yellow vein Fujian alphasatellite. Based on the threshold for the classification of Begomovirus, Betasatellite and Alphasatellite, YN-2023-WJ was designated as a new isolate of PepLCYnV, YN-2023-WJ-beta as a new isolate of ToLCCNB and YN-2023-WJ-alpha1 as a new member of AYVA, whereas YN-2023-WJ-alpha2 was identified as a new geminialphasatellite species, for which the name pepper leaf curl Yunnan alphasatellite (PepLCYnA) is proposed. To the best of our knowledge, this is the first report of L. sativa L. infection by PepLCYnV associated with ToLCCNB, AYVA and PepLCYnA, and L. sativa L. is a new host plant of Begomovirus. Full article

The demand for earth construction, primarily driven by environmental considerations, is currently growing. Earth, as a building material, has a very low carbon footprint and is easily recyclable, promoting a circular economy. It is also valued for its intrinsic qualities such as hygrothermal properties, air quality, acoustic performance, and esthetics. To meet this demand and promote earth construction, a better understanding of the local resources is essential. However, not all soils are suitable for earth construction, and their properties can significantly influence the final material performance. The assessment of soil suitability for earth construction requires both scientific rigor and practical field applicability. This study evaluates the correlation between traditional field-testing methods and standardized laboratory analyses through a comprehensive characterization of 39 soils from the Nouvelle-Aquitaine region in France. The research methodology integrated different field tests commonly used by practitioners, including sensory evaluations, plasticity tests, and cohesion assessments, with five standardized geotechnical tests covering particle size distribution, Atterberg limits, methylene blue value, organic matter content, and density measurements. The particle size distribution analysis revealed diverse soil compositions, with clay-sized particle content (<0.002 mm) ranging from 5% to 75%. Strong correlations were established between field and laboratory results, particularly between the cigar test and plasticity index (R² = 0.8863), and between ring test scores and clay-sized particle content percentages, validating the reliability of traditional testing methods. Plasticity indices varied from 0% to 50%, indicating different soil behaviors and potential applications. These correlations demonstrate that while traditional field tests provide reliable preliminary assessment tools, laboratory testing remains essential for final material validation. The results demonstrate that while several soils are directly suitable for various earth construction techniques, other soils falling outside conventional recommendation envelopes may still be suitable for specific construction techniques when appropriately evaluated and may require modification through sieving, mixing, or stabilization. Full article

Cadmium (Cd) ions can significantly affect plant growth and development. They promote plant growth up to a certain concentration, but high concentrations may inhibit normal plant growth. However, Cd pollution also threatens ecosystem security and may pose a potential risk to human health. Bioremediation has received significant attention as a method for reducing soil pollution, including Cd contamination. Therefore, this study evaluated the phytoremediation potential of Bougainvillea spectabilis Willd. (Triangle plum), Hibiscus rosa-sinensis Linn (Safflower), and Cuphea ignea (Cigar flower) in Cd-contaminated soil that simulated the conditions found in mine tailings ponds. The results indicated that there were significant differences in Cd ion accumulation among the three flowering shrubs. Triangle plum had the greatest enrichment ability, followed by Cigar flower and then Safflower. Triangle plum leaves showed the greatest enrichment ability, followed by the stems and roots. In contrast, the Cigar flower roots showed the greatest enrichment ability followed by the leaves and the stems. However, their translocation factor (TF) values were similar. The enrichment effect of Safflower leaves was the strongest, followed by its roots, with relatively little accumulation in its stems, and its TF value varied within a certain range. This study provides a scientific basis for the bioremediation of soil Cd pollution and new information about the abilities of different flowering shrubs and their parts to accumulate Cd. Full article

Background: There is limited evidence on how the United States Food and Drug Administration’s (FDA) proposed ban on menthol cigarettes and flavored cigars will impact individuals with mood disorders who smoke menthol cigarettes. This study aimed to evaluate how individuals with mood disorders who smoke menthol cigarettes might respond to a hypothetical ban on menthol cigarettes, explore the reasons for their current use, and examine how these reasons are associated with participants’ characteristics. Methods: Study data were collected at baseline from adults (18+ years) with mood disorders who participated in a randomized controlled trial evaluating the impact of gradual nicotine reduction. Participants were individuals who smoked and had no plan to quit in the next six months. They reported demographics and tobacco consumption patterns, interest in quitting, and responded to a hypothetical question on a potential ban on menthol cigarettes. The question asked participants which actions they would most likely take if menthol-flavored cigarettes were banned. Means and frequencies were used to describe the sample. Logistic regression was used to determine factors associated with each reason for menthol use (less harmful, better flavor, less harsh on the throat, and less harsh on the chest). Results: Participants (n = 77) were an average age of 42.5 (SD 12.5) years, 61% (n = 47) were female, 68.8% (n = 53) identified as White, and 5.2% (n = 4) identified as Hispanic. On average, participants reported currently smoking 18.1 (SD 9.9) cigarettes per day and had smoked for 23.9 (SD 13.6) years. About 58.4% of participants (n = 45) expressed their intention to switch to non-menthol cigarettes, 19.5% (n = 15) intended to transition to a different type of tobacco product, and 22.1% (n = 17) intended to quit smoking entirely without substitution. The most endorsed reason for using menthol cigarettes was better flavor (89.6%, n = 69/77), followed by less harshness on the throat (41.3%, n = 31/75) and chest (40%, n = 30/75), and the belief that they were less harmful than non-menthol cigarettes (24%, n = 18/75). Older age was associated with the belief that menthol cigarettes were less harmful (OR = 1.06; p = 0.02). Conclusion: Among individuals with mood disorders and who smoke menthol cigarettes and have no plans to quit smoking, 22.1% may try to quit smoking if a menthol ban is implemented, while the majority (58.4%) stated that they would switch to non-menthol cigarettes. As the reasons for using menthol cigarettes included perceived lower harm, there is a need for targeted public awareness campaigns to correct misconceptions about the harms of menthol cigarettes. Full article

Limited research has examined attention to these cigar-specific health warnings and their perceived effectiveness among young people. The objective of our study was to evaluate the attention to and perceptions of a set of cigar-specific health warnings among young adult tobacco users and non-users. Methods: Young adults ages 18–24 in Columbus, Ohio, were recruited into an eye-tracking experiment examining cigarillo packaging between May 2022 and February 2023. Participants (n = 124) were shown 12 unique, branded cigarillo packages featuring a rotation of four of the Food and Drug Administration’s mandated health warnings: (1) Cigar smoking can cause lung cancer and heart disease (“disease”); (2) tobacco smoke increases the risk of lung cancer and heart disease, even in nonsmokers (“nonsmokers”); (3) cigar smoking can cause cancers of the mouth and throat, even if you do not inhale (“inhale”); and (4) cigars are not a safe alternative to cigarettes (“alternative”). Software captured visual attention to each product package, including the health warning. Participants also ranked the most effective message to motivate people to quit; one week later, the participants (n = 118) self-reported unaided recall of the experiment. Results: Study participants were an average of 21.2 years old, 54.2% were female, 73.7% were White, 65.3% had some college education, and 26.3% reported tobacco use in the previous month. The health warning, “Cigar smoking can cause cancers of the mouth and throat, even if you do not inhale” was ranked the most effective cigar warning (41.5%) and drew the greatest proportion of visual attention (26.1%). More than half (52.5%) recalled details regarding the health warning messages one week following the experiment, with few recalling (17.7%) specific warning message themes. Conclusions: Understanding the best performing health warnings is a crucial strategy to share accurate information on the risks of tobacco use. Our findings suggest that the warning on cancer risk even without inhaling drew the greatest visual attention and highest rating of perceived effectiveness among this sample of young adult cigarillo users and non-users. Full article

A feasibility study on the compensation of 3D mispositioning errors of the probe occurring in the characterization of a long antenna, via a non-redundant (NR) near to far-field (NTFF) transformation with helicoidal scan, is conducted in this article. Such types of errors can result from imperfections in the rail driving the linear motion of the probe and from an imprecise synchronization of the linear and rotational movements of the probe and the antenna when drawing the scan helix. To correct them, an approach, which proceeds through two steps, is proposed. The former step uses a technique called cylindo rical wave (CW) correction for compensating the phase of the near-field (NF) samples, which, owing to the rail imperfections, result in not being acquired over the measurement cylinder surface. The latter exploits an iterative scheme to restore the samples at the sampling points required by the adopted NR representation along the scan helix from those obtained by applying the CW correction technique and impaired by 2D mispositioning errors. The so compensated NF samples are then effectively recovered via a 2D optimal sampling interpolation (OSI) scheme to accurately obtain the input data required to carry out the standard cylindrical NTFF transformation. The OSI representation is determined here by assuming a long antenna under test as enclosed in a prolate ellipsoid or cylinder ending into two hemispheres (cigar) in order to make, depending on the particular geometry of the considered antenna, the representation effectively non-redundant. The reported numerical simulation results show the capability of the proposed approach to compensate even severe 3D mispositioning errors, thus enabling its usage in a real measurement scenario. Full article

The increased volume of images and galaxies surveyed by recent and upcoming projects consolidates the need for accurate and scalable automated AI-driven classification methods. This paper proposes a new algorithm based on a custom neural network architecture for classifying galaxies from deep space surveys. The convolutional neural network (CNN) presented is trained using 10,000 galaxy images obtained from the Galaxy Zoo 2 dataset. It is designed to categorize galaxies into five distinct classes: completely round smooth, in-between smooth (falling between completely round and cigar-shaped), cigar-shaped smooth, edge-on, and spiral. The performance of the proposed CNN is assessed using a set of metrics such as accuracy, precision, recall, F1 score, and area under the curve. We compare our solution with well-known architectures like ResNet-50, DenseNet, EfficientNet, Inception, MobileNet, and one proposed model for galaxy classification found in the recent literature. The results show an accuracy rate of 96.83%, outperforming existing algorithms. Full article

To promote the resource utilization of steel slag and improve the production process of steel slag in steelmaking plants, this research studied the characteristics of three different processed steel slags from four steelmaking plants. The physical and mechanical characteristics and volume stability of steel slags were analyzed through density, water absorption, and expansion tests. The main mineral phases, morphological characteristics, and thermal stability of the original steel slag and the steel slag after the expansion test are analyzed with X-ray diffractometer (XRD), scanning electron microscope (SEM), and thermogravimetric analysis (TG) tests. The results show that the composition of steel slag produced by different processes is similar. The main active substances of other processed steel slags are dicalcium silicate (C₂S), tricalcium silicate (C₃S), CaO, and MgO. After the expansion test, the main chemical products of steel slag are CaCO₃, MgCO₃, and calcium silicate hydrate (C-S-H). Noticeable mineral crystals appeared on the surface of the steel slag after the expansion test, presenting tetrahedral or cigar-like protrusions. The drum slag had the highest density and water stability. The drum slag had the lowest porosity and the densest microstructure surface, compared with steel slags that other methods produce. The thermal stability of steel slag treated by the hot splashing method was relatively higher than that of steel slag treated by the other two methods. Full article

Tobacco (Nicotiana tabacum L.) is a major industrial crop that has being cultivated for centuries for the manufacturing of cigarettes, cigars, and other smoking products. Due to its negative effects on both human health and the environment, the European Union has adopted strict policies that aspire to reduce the consumption of tobacco. Herbal cigarettes are alternative smoking products that are often advertised as healthier than conventional tobacco cigarettes and are especially popular in Asian markets. Even though the available literature suggests that they are equally detrimental to human health, the introduction of tobacco-alternative crops (TACs) to the European tobacco industry could smoothen the abandonment of tobacco, and eventually smoking products altogether, in the EU. The aim of the present systematic review was to compile a list of possible TACs that could be incorporated in the European smoking industry, and highlight their strengths and weaknesses. The most dominant crops in the literature (and in the existing market products) were calendula (Calendula officinalis L.), mullein (Verbascum thapsus L.), ginseng (Panax ginseng C.A.Mey.), tea (Camellia sinensis (L.) Kuntze), chamomile (Matricaria chamomilla L.), and mentha (Mentha spp.). Even though these crops are promising, further research is required for their incorporation in the European tobacco industry. Full article