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29 Results Found

  • Article
  • Open Access
16 Citations
5,360 Views
14 Pages

Appetitive aggression, i.e., the motivation to obtain rewards through aggressive behaviors, has been suggested as a key driver of cyberbullying. Due to the contextual properties of cyberspace (e.g., anonymity), it is assumed that the negative effects...

  • Article
  • Open Access
2 Citations
2,001 Views
8 Pages

Numerous studies have linked lower levels of serum cholesterol with heightened aggression, violent crimes, and violent deaths across diverse populations, including forensic psychiatric patients, criminals, and the broad public. Interestingly, this as...

  • Article
  • Open Access
1 Citations
2,073 Views
12 Pages

21 February 2025

Adverse childhood experiences (ACEs) represent one of the most critical factors contributing to the manifestation of psychiatric disorders later in life. Furthermore, such experiences are often associated with deficits in interpersonal relationships,...

  • Article
  • Open Access
11 Citations
5,700 Views
11 Pages

Aggression and violent offenses are common amongst forensic psychiatric patients. Notably, research distinguishes two motivationally distinct dimension of aggression–instrumental and reactive aggression. Instrumental aggression comprises of appetitiv...

  • Article
  • Open Access
64 Citations
10,541 Views
24 Pages

Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation

  • Gilbert Audira,
  • Sreeja Sarasamma,
  • Jung-Ren Chen,
  • Stevhen Juniardi,
  • Bonifasius Putera Sampurna,
  • Sung-Tzu Liang,
  • Yu-Heng Lai,
  • Geng-Ming Lin,
  • Ming-Chia Hsieh and
  • Chung-Der Hsiao

13 December 2018

Leptin, a hormone secreted by peripheral adipose tissues, regulates the appetite in animals. Recently, evidence has shown that leptin also plays roles in behavioral response in addition to controlling appetite. In this study, we examined the potentia...

  • Article
  • Open Access
4 Citations
2,684 Views
10 Pages

Blood Levels of Neuropeptide 26RFa in Relation to Anxiety and Aggressive Behavior in Humans—An Exploratory Study

  • Henning Værøy,
  • Saloua Takhlidjt,
  • Yamina Cherifi,
  • Emilie Lahaye,
  • Nicolas Chartrel and
  • Serguei O. Fetissov

31 January 2023

26RFa, also referred to as QRFP, is a hypothalamic neuropeptide mainly known for its role in the regulation of appetite and glucose metabolism. Its possible relevance to emotional regulation is largely unexplored. To address this, in the present expl...

  • Article
  • Open Access
8 Citations
5,129 Views
24 Pages

Synthesis, Structural and Behavioral Studies of Indole Derivatives D2AAK5, D2AAK6 and D2AAK7 as Serotonin 5-HT1A and 5-HT2A Receptor Ligands

  • Agnieszka A. Kaczor,
  • Ewa Kędzierska,
  • Tomasz M. Wróbel,
  • Angelika Grudzińska,
  • Angelika Pawlak,
  • Tuomo Laitinen and
  • Agata Bartyzel

2 January 2023

Serotonin receptors are involved in a number of physiological functions and regulate aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, and thermoregulation. Here we report synthesis and detailed structural and behaviora...

  • Review
  • Open Access
54 Citations
14,761 Views
21 Pages

26 September 2020

Rearranged during transfection (RET) is the tyrosine kinase receptor that under normal circumstances interacts with ligand at the cell surface and mediates various essential roles in a variety of cellular processes such as proliferation, differentiat...

  • Review
  • Open Access
8 Citations
11 Views

Large-scale social upheavals have profound effects at the level of the individual, primarily in the form of trauma-related psychological disorders. Narrative exposure therapy (NET) was developed and assessed to treat post-traumatic stress disorder (P...

  • Article
  • Open Access
6 Citations
3,260 Views
16 Pages

13 December 2024

With generative Artificial Intelligence (AI) capturing public attention, the appetite of the technology sector for larger and more complex Deep Learning (DL) models is continuously growing. Traditionally, the focus in DL model development has been on...

  • Article
  • Open Access
6 Citations
3,642 Views
11 Pages

Effect of Dorper Rams’ Social-Sexual Hierarchy on Their Sexual Behavior and Capacity to Induce Estrus in Ewes

  • Andrea González-Tavizón,
  • César A. Meza-Herrera,
  • Gerardo Arellano-Rodríguez,
  • Miguel Mellado,
  • Viridiana Contreras-Villarreal,
  • Oscar Ángel-García,
  • José R. Arévalo and
  • Francisco G. Véliz-Deras

This study aimed to assess the influence of the social rank of rams and quality of stimuli to ewes between dominant and subordinate Dorper rams joined to anestrus ewes. Social rank was evaluated for two days (ESR; n = 36); rams were exposed to estrog...

  • Article
  • Open Access
2 Citations
1,372 Views
12 Pages

Leptin, a hormone primarily produced by adipose tissue, regulates energy balance and appetite, while contributing significantly to obesity and cancer progression. Vasculogenic mimicry (VM) refers to the process by which aggressive tumor cells form bl...

  • Review
  • Open Access
15 Citations
5,322 Views
14 Pages

Heartland Virus Disease—An Underreported Emerging Infection

  • Zygmunt F. Dembek,
  • Jerry L. Mothershead,
  • Christopher M. Cirimotich and
  • Aiguo Wu

First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick specie...

  • Article
  • Open Access
6 Citations
3,811 Views
18 Pages

Fentanyl Induces Novel Conditioned Place Preference in Adult Zebrafish, Disrupts Neurotransmitter Homeostasis, and Triggers Behavioral Changes

  • Yuanzhao Wu,
  • Anli Wang,
  • Lixiang Fu,
  • Meng Liu,
  • Kang Li,
  • Song Chian,
  • Weixuan Yao,
  • Binjie Wang and
  • Jiye Wang

Abuse of new psychoactive substances increases risk of addiction, which can lead to serious brain disorders. Fentanyl is a synthetic opioid commonly used in clinical practice, and behavioral changes resulting from fentanyl addiction have rarely been...

  • Article
  • Open Access
4 Citations
2,509 Views
17 Pages

Multifaceted Interplay among Social Dominance, Body Condition, Appetitive and Consummatory Sexual Behaviors, and Semen Quality in Dorper Rams during Out-Of-Season and Transition Periods

  • Pablo I. Sifuentes-Lamónt,
  • Cesar A. Meza-Herrera,
  • Francisco G. Véliz-Deras,
  • Alan S. Alvarado-Espino,
  • Ariadna V. Alvarado-Espino,
  • Guadalupe Calderón-Leyva,
  • Oscar Angel-Garcia,
  • Dalia I. Carrillo-Moreno,
  • Viridiana Contreras-Villarreal and
  • Jorge A. Bustamante-Andrade
  • + 1 author

29 November 2022

Dorper rams (n = 24) were evaluated during the sexual resting season to determine their social rank (SR), either high (HSR) or low (LSR), under intensive management conditions in northern Mexico (25° N). Aggressive behaviors were quantified durin...

  • Article
  • Open Access
8 Citations
2,347 Views
12 Pages

Post-Diagnostic Support for Behaviour Changes in Young-Onset Dementia in Australia

  • Claire J. Cadwallader,
  • Dennis Velakoulis and
  • Samantha M. Loi

30 October 2023

Behaviour changes (BCs) are common in young-onset dementia (YOD). Access to knowledgeable and age-appropriate support services is needed to assist with the appropriate management of BCs. We sought to investigate the types of YOD-related BCs that most...

  • Article
  • Open Access
16 Citations
6,584 Views
14 Pages

Virulence of Marburg Virus Angola Compared to Mt. Elgon (Musoke) in Macaques: A Pooled Survival Analysis

  • Paul W. Blair,
  • Maryam Keshtkar-Jahromi,
  • Kevin J. Psoter,
  • Ronald B. Reisler,
  • Travis K. Warren,
  • Sara C. Johnston,
  • Arthur J. Goff,
  • Lydia G. Downey,
  • Sina Bavari and
  • Anthony P. Cardile

21 November 2018

Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is...

  • Case Report
  • Open Access
2 Citations
3,868 Views
14 Pages

Preventive Healthcare and Management for Acute Lymphoblastic Leukaemia in Adults: Case Report and Literature Review

  • Wei-Ping Chen,
  • Wen-Fang Chiang,
  • Hung-Ming Chen,
  • Jenq-Shyong Chan and
  • Po-Jen Hsiao

Acute lymphoblastic leukaemia (ALL) is diagnosed by the presence of at least 20% lymphoblasts in the bone marrow. ALL may be aggressive and include the lymph nodes, liver, spleen, central nervous system (CNS), and other organs. Without early recognit...

  • Case Report
  • Open Access
1 Citations
1,706 Views
9 Pages

24 February 2025

Background: Hemophagocytic lymphohistiocytosis (HLH) is an aggressive, life-threatening condition commonly observed in young children. Distinguishing primary HLH from secondary HLH, such as malignancy-associated HLH, can be challenging, potentially l...

  • Article
  • Open Access
1 Citations
2,313 Views
16 Pages

13 August 2024

The experience of bearing witness to the lack of appetite and involuntary weight loss that characterizes cancer anorexia–cachexia syndrome (CACS) is reported to be stressful for family members. Research identifies that family members engage in...

  • Article
  • Open Access
9 Citations
3,950 Views
19 Pages

Dravet Syndrome—The Polish Family’s Perspective Study

  • Justyna Paprocka,
  • Anita Lewandowska,
  • Piotr Zieliński,
  • Bartłomiej Kurczab,
  • Ewa Emich-Widera and
  • Tomasz Mazurczak

28 April 2021

Aim: The aim of the paper is to study the prevalence of Dravet Syndrome (DS) in the Polish population and indicate different factors other than seizures reducing the quality of life in such patients. Method: A survey was conducted among caregivers of...

  • Article
  • Open Access
6 Citations
3,174 Views
15 Pages

11 February 2021

Since investors have diverse risk motives for green investments, this paper uses data envelopment analysis (DEA) and simulation to accurately evaluate the efficiency of green portfolios from the perspective of investors’ subjective risks and accordin...

  • Systematic Review
  • Open Access
1 Citations
1,722 Views
30 Pages

3 November 2025

Background: Patients with hematologic malignancy (HM) experience high symptom burden (SB) and diminished quality of life (QOL). While early palliative care (EPC) benefits solid tumors, its impact in HM remains uncertain. Objectives: To systematically...

  • Article
  • Open Access
1,082 Views
18 Pages

Clinical Profiles and Medication Predictors in Early Childhood Psychiatric Referrals: A 10-Year Retrospective Study

  • Leyla Bozatlı,
  • Hasan Cem Aykutlu,
  • Cansu Uğurtay Dayan,
  • Tuğçe Ataş,
  • Esra Nisa Arslan,
  • Yeşim Özge Gündüz Gül and
  • Işık Görker

4 June 2025

Background and Objectives: Although psychiatric disorders in early childhood are increasingly recognized, comprehensive clinical data from large samples in this age group remain limited. This study presents one of the largest and longest-term evaluat...

  • Review
  • Open Access
7 Citations
12,667 Views
15 Pages

The Evolving Role of Cannabidiol-Rich Cannabis in People with Autism Spectrum Disorder: A Systematic Review

  • Bilal Jawed,
  • Jessica Elisabetta Esposito,
  • Riccardo Pulcini,
  • Syed Khuram Zakir,
  • Matteo Botteghi,
  • Francesco Gaudio,
  • Daniele Savio,
  • Caterina Martinotti,
  • Stefano Martinotti and
  • Elena Toniato

20 November 2024

Autism spectrum disorder (ASD) is a neurological disease and lifelong condition. The treatment gap in ASD has led to growing interest in alternative therapies, particularly in phytocannabinoids, which are naturally present in Cannabis sativa. Studies...

  • Article
  • Open Access
9 Citations
5,166 Views
26 Pages

6 July 2019

Objective: The Nile rat (Arvicanthis niloticus) is a superior model for Type-II Diabetes Mellitus (T2DM) induced by diets with a high glycemic index (GI) and glycemic load (GLoad). To better define the age and gender attributes of diabetes in early s...

  • Review
  • Open Access
1 Citations
2,827 Views
21 Pages

15 August 2025

Background/Objectives: Chemotherapy is an aggressive form of oncological treatment often accompanied by numerous adverse effects. A patient’s baseline status significantly influences the course of therapy, its efficacy, quality of life, and ove...

  • Abstract
  • Open Access
1,381 Views
2 Pages

War-Induced Disrupted Eating Behaviors in Ukrainian School-Aged Children

  • Mariia Gulich,
  • Dina Fedorova,
  • Olena Petrenko,
  • Henna Vepsäläinen and
  • Maijaliisa Erkkola

Background and objectives: Russian military aggression in Ukraine has exposed children to extremely high levels of acute and chronic stressors that are incomparable to stress levels in peaceful countries. Such stressors can impact children’s ea...

  • Review
  • Open Access
7 Citations
3,674 Views
20 Pages

Immunonutrition in ERAS Protocol for Patients with Gynecologic Cancer: A Narrative Review of the Literature

  • Vasilios Lygizos,
  • Dimitrios Haidopoulos,
  • Dimitrios Efthymios Vlachos,
  • Antonia Varthaliti,
  • Maria Fanaki,
  • George Daskalakis,
  • Nikolaos Thomakos and
  • Vasilios Pergialiotis

18 March 2025

In-hospital patients who are in the gynecologic oncology setting often suffer from malnutrition, which is one of the primary problems, the rate of which reportedly ranges from 28% to 70%. Malnutrition is a significant risk factor for immunosuppressio...