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50 Results Found

  • Review
  • Open Access
94 Citations
15,569 Views
16 Pages

Climate change has the potential to have many significant impacts on aeroallergens such as pollen and mould spores, and therefore related diseases such as asthma and allergic rhinitis. This paper critically reviews this topic, with a focus on the pot...

  • Review
  • Open Access
5 Citations
16,084 Views
15 Pages

ARIA Care Pathways 2019: Next-Generation Allergic Rhinitis Care and Allergen Immunotherapy in Malaysia

  • Amir Hamzah Abdul Latiff,
  • Salina Husain,
  • Baharudin Abdullah,
  • Palaniappan Suppiah,
  • Vincent Tan,
  • Tang Ing Ping,
  • Kent Woo,
  • Yoke-Yeow Yap,
  • Claus Bachert and
  • Holger J. Schunemann
  • + 3 authors

An increase in the prevalence of allergic rhinitis (AR) worldwide presents a significant burden to the health care system. An initiative was started in Europe designated as Allergic Rhinitis and Its Impact on Asthma (ARIA) to develop internationally...

  • Feature Paper
  • Review
  • Open Access
11 Citations
5,577 Views
11 Pages

While allergy, asthma and rhinitis do not inevitably co-exist, there are strong associations. Not all those with asthma are allergic, rhinitis may exist without asthma, and allergy commonly exists in the absence of asthma and/or rhinitis. This is lik...

  • Article
  • Open Access
7 Citations
3,189 Views
10 Pages

Association between Physical Activity and Respiratory Diseases in Adolescents: An Age- and Gender-Matched Study

  • Jeong-Hui Park,
  • Eunhye Yoo,
  • Myong-Won Seo,
  • Hyun Chul Jung and
  • Jung-Min Lee

The purpose of the present cross-sectional study was to examine the impacts of allergic respiratory diseases on physical activity (PA), sedentary behaviors (SB), and body mass index (BMI) by matching age and gender with those adolescents without alle...

  • Article
  • Open Access
14 Citations
3,728 Views
12 Pages

The prevalence of allergic diseases has been increasing globally prior to COVID-19. The pandemic resulted in changes in lifestyle and personal habits such as universal mask-wearing and social distancing. However, there is insufficient information on...

  • Discussion
  • Open Access
15 Citations
5,897 Views
9 Pages

17 June 2020

Asthma and allergic rhinitis are the most common chronic childhood diseases with an increasing prevalence worldwide. There is an urgent need to look for methods of preventing allergic diseases from an early age. The relationship between vitamin D sta...

  • Article
  • Open Access
24 Citations
13,590 Views
14 Pages

Managing Allergic Rhinitis in the Pharmacy: An ARIA Guide for Implementation in Practice

  • Olga Lourenço,
  • Sinthia Bosnic-Anticevich,
  • Elísio Costa,
  • João A. Fonseca,
  • Enrica Menditto,
  • Biljana Cvetkovski,
  • Vicky Kritikos,
  • Rachel Tan,
  • Anna Bedbrook and
  • Sophie Scheire
  • + 12 authors

The paradigm of how we manage allergic rhinitis is shifting with a growing understanding that it is a complex process, requiring a coordinated effort from healthcare providers and patients. Pharmacists are key members of these integrated care pathway...

  • Review
  • Open Access
6 Citations
14,654 Views
13 Pages

16 February 2024

The treatment of allergic conditions presents a challenge for both seasonal allergic rhinitis and perennial rhinitis sufferers. The increasing prevalence of both of these types of allergic responses requires the use of a range of treatments which can...

  • Article
  • Open Access
16 Citations
3,709 Views
11 Pages

Asthma, rhinitis, and eczema are becoming increasingly prevalent among children in China. Studies have shown that the perinatal period is critical and impacts children’s health. However, research on the associations between perinatal factors and chil...

  • Article
  • Open Access
1 Citations
2,341 Views
14 Pages

Background: Pollen exposure in early life is shown to be associated with allergy and asthma. DNA methylation (DNAm), an epigenetic marker, potentially reacts to pollen. However, the role of at-birth DNAm between prenatal pollen grain (PPG) exposure a...

  • Review
  • Open Access
78 Citations
27,004 Views
11 Pages

Review of Rhinitis: Classification, Types, Pathophysiology

  • Georgia A. Liva,
  • Alexander D. Karatzanis and
  • Emmanuel P. Prokopakis

19 July 2021

Rhinitis describes a pattern of symptoms as a result of nasal inflammation and/or dysfunction of the nasal mucosa. It is an umbrella entity that includes many different subtypes, several of which escape of complete characterization. Rhinitis is consi...

  • Review
  • Open Access
4 Citations
3,133 Views
11 Pages

Rhinitis in the Geriatric Population: Epidemiological and Cytological Aspects

  • Matteo Gelardi,
  • Rossana Giancaspro,
  • Elisa Boni,
  • Mario Di Gioacchino,
  • Giulia Cintoli,
  • Michele Cassano and
  • Maria Teresa Ventura

Allergic rhinitis (AR), traditionally considered as a childhood condition, is increasingly recognized among older adults, driven by rising life expectancy and environmental factors. Although allergic sensitization declines with age, AR prevalence in...

  • Review
  • Open Access
22 Citations
11,870 Views
13 Pages

Anthropogenic Climate Change and Allergic Diseases

  • James Blando,
  • Leonard Bielory,
  • Viann N. Nguyen-Feng,
  • Rafael Diaz and
  • Hueiwang Anna Jeng

28 February 2012

Climate change is expected to have an impact on various aspects of health, including mucosal areas involved in allergic inflammatory disorders that include asthma, allergic rhinitis, allergic conjunctivitis and anaphylaxis. The evidence that links cl...

  • Article
  • Open Access
33 Citations
12,441 Views
11 Pages

Diagnosis of Obstructive Sleep Apnea in Patients with Allergic and Non-Allergic Rhinitis

  • Annalisa Pace,
  • Giannicola Iannella,
  • Valeria Rossetti,
  • Irene Claudia Visconti,
  • Giampiero Gulotta,
  • Carlo Cavaliere,
  • Andrea De Vito,
  • Antonino Maniaci,
  • Salvatore Cocuzza and
  • Giuseppe Magliulo
  • + 1 author

8 September 2020

Background and objectives: Rhinitis could be considered a risk factor for obstructive sleep apnea (OSA). Studies were conducted to evaluate the relation between OSA and Allergic rhinitis (AR). Non-allergic rhinitis with eosinophilia syndrome (NARES)...

  • Article
  • Open Access
11 Citations
2,731 Views
10 Pages

Applicability of the MASK-Air® App to Severe Asthma Treated with Biologic Molecules: A Pilot Study

  • Alida Benfante,
  • Bernardo Sousa-Pinto,
  • Gianluca Pillitteri,
  • Salvatore Battaglia,
  • Joao Fonseca,
  • Jean Bousquet and
  • Nicola Scichilone

29 September 2022

MASK-air®, a good practice of the DG Santé, has been fully validated in allergic rhinitis, but little is known about its applicability to asthmatics. We explored whether the MASK-air® application is applicable to patients with severe a...

  • Review
  • Open Access
8 Citations
6,924 Views
13 Pages

New Developments in Climate Change, Air Pollution, Pollen Allergy, and Interaction with SARS-CoV-2

  • Gennaro D’Amato,
  • Isabella Annesi-Maesano,
  • Benedetta Biagioni,
  • Andrea Lancia,
  • Lorenzo Cecchi,
  • Maria Concetta D’Ovidio and
  • Maria D’Amato

In recent years, the environmental impacts of climate change have become increasingly evident. Extreme meteorological events are influenced by climate change, which also alter the magnitude and pattern of precipitations and winds. Climate change can...

  • Article
  • Open Access
1 Citations
1,233 Views
13 Pages

Sensitization Patterns to Aeroallergens and Food Allergens Among Children with Atopic Asthma in Southwestern Saudi Arabia

  • Ali Alsuheel Asseri,
  • Mashael Abdualslam Abuaqil,
  • Abdulaziz Saud Alotaibi,
  • Wajd Abdualslam Abuaqil,
  • Abdulaziz Saeed Alqahtani,
  • Lama Ali Asiri,
  • Mona Alkhayri,
  • Amal Y. Moshebah and
  • Faten M. ElAbd

29 April 2025

Background and Objectives: Asthma is a prevalent chronic respiratory disease in children, with increasing rates in Saudi Arabia. Allergen sensitization plays a crucial role in asthma development and severity. This study aimed to investigate the preva...

  • Article
  • Open Access
11 Citations
3,301 Views
10 Pages

We examined the effect of long-term changes in environmental factors on the prevalence of allergic diseases in elementary school students in Ulsan, Korea. This longitudinal study was conducted among 390 students who were enrolled from three elementar...

  • Review
  • Open Access
647 Views
5 Pages

29 January 2010

Ostatnio opublikowane międzynarodowe raporty: Światowej Inicjatywy Zwalczania Astmy, PRACTicing ALLergology i Allergic Rhinitis and its Impact on Asthma rekomendują leki przeciwleukotrienowe w terapii astmy u dorosłych i u dzieci oraz w alergicznym n...

  • Review
  • Open Access
3 Citations
3,030 Views
12 Pages

The Potential Role of Nasal Cytology in Respiratory Diseases: Clinical Research and Future Perspectives

  • Giuseppina Marcuccio,
  • Giuseppina Raffio,
  • Pasquale Ambrosino,
  • Claudio Candia,
  • Elena Cantone,
  • Aikaterini Detoraki and
  • Mauro Maniscalco

29 January 2025

Nasal cytology is a non-invasive, affordable, and easily executable technique commonly used in research to study rhinitis and, to a lesser extent, chronic rhinosinusitis. It is particularly useful for the differential diagnosis of non-allergic rhinit...

  • Article
  • Open Access
2 Citations
805 Views
8 Pages

22 October 2014

Introduction: The clinical efficacy of sublingual immunotherapy (SLIT) has already been proven and is known to be high. Its influence on the immunological system of patients suffering from bronchial asthma was also examined. However, it is still uncl...

  • Article
  • Open Access
4 Citations
3,368 Views
11 Pages

Impact of Snoring on Telomere Shortening in Adolescents with Atopic Diseases

  • Keith T. S. Tung,
  • Rosa S. Wong,
  • Hing-Wai Tsang,
  • Gilbert T. Chua,
  • Dicky Chan,
  • Kate C. Chan,
  • Wilfred H. S. Wong,
  • Jason C. Yam,
  • Marco Ho and
  • Clement C. Tham
  • + 3 authors

18 May 2021

Atopic diseases can impose a significant burden on children and adolescents. Telomere length is a cellular marker of aging reflecting the impact of cumulative stress exposure on individual health. Since elevated oxidative stress and inflammation burd...

  • Review
  • Open Access
4,637 Views
17 Pages

The interplay between allergic diseases and neurological disorders has gained increasing attention over the past decades, highlighting potential shared pathophysiological pathways. Allergic diseases, including asthma, eczema, and allergic rhinitis, a...

  • Feature Paper
  • Review
  • Open Access
69 Citations
17,009 Views
9 Pages

The Role of Probiotics in Preventing Allergic Disease

  • Helen T. Wang,
  • Sara Anvari and
  • Katherine Anagnostou

5 February 2019

The prevalence of allergic disorders has been increasing worldwide and significantly impacts the quality of life of the atopic individual. There has been an increased interest in the role of probiotics for the prevention and treatment of allergic dis...

  • Article
  • Open Access
4 Citations
5,882 Views
14 Pages

Can Breastfeeding Prevent Long-Term Overweight and Obesity in Children? A Population-Based Cohort Study

  • Carolina Roldão,
  • Rita Lopes,
  • Joana Matos Silva,
  • Natália Neves,
  • Joana Costa Gomes,
  • Cristina Gavina and
  • Tiago Taveira-Gomes

16 August 2024

The aims of this study were to assess the impact of exclusive breastfeeding up to 6 months of age on reducing the incidence of overweight and obesity in children up to 10 years of age and to estimate the annual incidence of obesity and overweight in...

  • Review
  • Open Access
12 Citations
7,696 Views
22 Pages

Mast Cells in Upper and Lower Airway Diseases: Sentinels in the Front Line

  • Giovanni Costanzo,
  • Giulia Anna Maria Luigia Costanzo,
  • Lorenzo Del Moro,
  • Emanuele Nappi,
  • Corrado Pelaia,
  • Francesca Puggioni,
  • Giorgio Walter Canonica,
  • Enrico Heffler and
  • Giovanni Paoletti

Mast cells (MCs) are fascinating cells of the innate immune system involved not only in allergic reaction but also in tissue homeostasis, response to infection, wound healing, protection against kidney injury, the effects of pollution and, in some ci...

  • Article
  • Open Access
13 Citations
4,022 Views
11 Pages

Cohort Study of Maternal Gestational Weight Gain, Gestational Diabetes, and Childhood Asthma

  • Orianne Dumas,
  • Anna Chen Arroyo,
  • Mohammad Kamal Faridi,
  • Kaitlyn James,
  • Sarah Hsu,
  • Camille Powe and
  • Carlos A. Camargo

6 December 2022

Data on the association of maternal gestational weight gain (GWG) and gestational diabetes mellitus (GDM) with childhood asthma are limited and inconsistent. We aimed to investigate these associations in a U.S. pre-birth cohort. Analyses included 16,...

  • Review
  • Open Access
31 Citations
5,442 Views
16 Pages

A Review of the Respiratory Health Burden Attributable to Short-Term Exposure to Pollen

  • Nur Sabrina Idrose,
  • Caroline J. Lodge,
  • Bircan Erbas,
  • Jo A. Douglass,
  • Dinh S. Bui and
  • Shyamali C. Dharmage

Respiratory diseases such as asthma, allergic rhinitis (AR) and chronic obstructive pulmonary disease (COPD) affect millions worldwide and pose a significant global public health burden. Over the years, changes in land use and climate have increased...

  • Review
  • Open Access
32 Citations
6,924 Views
22 Pages

Atopic dermatitis (AD) affects up to 20% of children and is considered the starting point of the atopic march with the development of food allergy, asthma, and allergic rhinitis. The heterogeneous phenotype reflects distinct and/or overlapping pathog...

  • Review
  • Open Access
20 Citations
10,389 Views
16 Pages

9 October 2023

There has been an insurgence of allergic respiratory diseases such as asthma and rhinitis in industrialized countries in the last few decades as a result of the interaction between air pollutants and pollen, which has become a global and dramatic hea...

  • Review
  • Open Access
11 Citations
4,302 Views
14 Pages

17 December 2021

Atopic dermatitis (AD) has been increasing in prevalence over the past few decades; however, AD has never been analyzed using a bibliometric approach. We searched for AD studies in the dermatology and allergy category of the Web of Science and SCOPUS...

  • Systematic Review
  • Open Access
22 Citations
7,981 Views
23 Pages

Adherence to the Mediterranean Diet in Children and Adolescents and Association with Multiple Outcomes: An Umbrella Review

  • Alice Masini,
  • Laura Dallolio,
  • Francesco Sanmarchi,
  • Francesco Lovecchio,
  • Mario Falato,
  • Yari Longobucco,
  • Marcello Lanari and
  • Rossella Sacchetti

9 February 2024

The Mediterranean Diet (MD) has been linked to numerous health benefits. This umbrella review aims to synthesize evidence from systematic reviews on the MD’s impact on children and adolescents aged 6 to 19 years. Following Joanna Briggs Institu...

  • Article
  • Open Access
11 Citations
4,483 Views
13 Pages

7 November 2018

Background and objective: the global prevalence of allergic rhinitis (AR) is rising and yet there is scarce information concerning the diagnosis, management and treatment patterns of AR in Northern Cyprus (NC). This study aims to provide a unique per...

  • Article
  • Open Access
2 Citations
5,737 Views
13 Pages

Food Sensitization Impact on Asthma Attacks in Children According to Age Group

  • Snezhina Lazova,
  • Diana Hristova,
  • Stamatios Priftis and
  • Tsvetelina Velikova

27 April 2022

Introduction: The progression of allergy disorders is termed “atopic march.” Having one allergic disorder increases the likelihood of acquiring others. Asthma and food allergies often coexist. There are no thresholds for specific IgE (sIg...

  • Article
  • Open Access
3 Citations
2,643 Views
12 Pages

Synthesis of MOFs and Characterization and Drug Loading Efficiency

  • Chuang Wu and
  • Haithm Yahya Mohammed Almuaalemi

Asthma and allergic rhinitis (AR) stand as prevalent chronic ailments impacting children within the United States. It is approximated that as many as 40% of American children exhibit symptoms indicative of AR, a condition which, if inadequately manag...

  • Review
  • Open Access
51 Citations
8,449 Views
12 Pages

Climate Change and Childhood Respiratory Health: A Call to Action for Paediatricians

  • Maria Elisa Di Cicco,
  • Giuliana Ferrante,
  • Doriana Amato,
  • Antonino Capizzi,
  • Carlo De Pieri,
  • Valentina Agnese Ferraro,
  • Maria Furno,
  • Valentina Tranchino and
  • Stefania La Grutta

Climate change (CC) is one of the main contributors to health emergencies worldwide. CC appears to be closely interrelated with air pollution, as some pollutants like carbon dioxide (CO2), nitrogen oxides (NOx) and black carbon are naturally occurrin...

  • Article
  • Open Access
3 Citations
3,490 Views
10 Pages

Background: Global awareness of ambient air pollution has heightened due to its detrimental impact on health, particularly in regions with elevated PM2.5 levels. Chiang Mai has emerged as an area experiencing the highest PM2.5 levels in Thailand. Obj...

  • Review
  • Open Access
31 Citations
9,246 Views
25 Pages

From an evolutionary perspective, lipoproteins are not only lipid transporters, but they also have important functions in many aspects of immunity. High-density lipoprotein (HDL) particles are the most abundant lipoproteins and the most heterogeneous...

  • Review
  • Open Access
8,120 Views
14 Pages

26 September 2024

Nasal polyposis is defined as a Th2-driven chronic inflammation of the nose and sinus with polyps visible in the nasal fossae. It is a prevalent disease with a significant impact on health-related quality of life (HRQL). Allergies, allergic rhinitis,...

  • Review
  • Open Access
4 Citations
10,800 Views
13 Pages

Bleaching Agents: A Review of Their Utilization and Management

  • Deepali Kulkarni,
  • Dipika Jaspal,
  • Nilisha Itankar,
  • Petros Petrounias,
  • Aikaterini Rogkala and
  • Paraskevi Lampropoulou

20 October 2024

Exposure to disinfectants, cleansers, and bleaching chemicals irritates the eyes, respiratory systems, and skin, triggering asthma and allergic rhinitis symptoms. Bleach, as the major constituent of cleansers, when used improperly or mixed with other...

  • Article
  • Open Access
1 Citations
763 Views
5 Pages

Exhaled Nitric Oxide in Patients with Esophagitis

  • Anna Dor-Wojnarowska,
  • Jerzy Liebhart,
  • Marcin Grabowski,
  • Leszek Czapla,
  • Krzysztof Grabowski and
  • Bernard Panaszek

15 June 2011

Introduction: Assessment of nitric oxide (NO) concentration in exhaled air is broadly used to monitor the airway inflammation in asthma. High levels of NO are also observed in paranasal sinuses and gastrointestinal tract (GT). Properly functioning es...

  • Review
  • Open Access
56 Citations
7,091 Views
15 Pages

Respiratory and Allergic Effects in Children Exposed to Pesticides—A Systematic Review

  • Rafael Junqueira Buralli,
  • Amana Freitas Dultra and
  • Helena Ribeiro

Pesticide exposure may affect children’s respiratory and allergic health, although results from epidemiological studies have not reached consensus. This review aims to analyze the scientific evidence on respiratory and allergic effects of expos...

  • Brief Report
  • Open Access
11 Citations
6,347 Views
5 Pages

Dust Storms from Degraded Drylands of Asia: Dynamics and Health Impacts

  • Shinji Otani,
  • Yasunori Kurosaki,
  • Youichi Kurozawa and
  • Masato Shinoda

24 November 2017

Asian dust events are massive meteorological phenomena during which dust particles from Chinese and Mongolian deserts are blown into the atmosphere and carried by westerly winds across Northeast Asia. Recently, there has been steady increase in both...

  • Article
  • Open Access
2 Citations
1,590 Views
21 Pages

Breaking Barriers: The Detrimental Effects of Combined Ragweed and House Dust Mite Allergen Extract Exposure on the Bronchial Epithelium

  • Răzvan-Ionuț Zimbru,
  • Manuela Grijincu,
  • Gabriela Tănasie,
  • Elena-Larisa Zimbru,
  • Florina-Maria Bojin,
  • Roxana-Maria Buzan,
  • Tudor-Paul Tamaș,
  • Monica-Daniela Cotarcă,
  • Octavia Oana Harich and
  • Raul Pătrașcu
  • + 5 authors

9 April 2025

(1) Background: Respiratory allergens, particularly ragweed (RW) pollen and house dust mites (HDMs), are major triggers of respiratory inflammation and allergic diseases. This study investigated the impact of single- versus combined-allergen exposure...

  • Article
  • Open Access
6 Citations
2,568 Views
12 Pages

Asthma and Cacosmia Could Be Predictive Factors of Olfactory Dysfunction Persistence 9 Months after SARS-CoV-2 Infection: The ANOSVID Study

  • Can Tipirdamaz,
  • Souheil Zayet,
  • Molka Osman,
  • Julien Mercier,
  • Elodie Bouvier,
  • Vincent Gendrin,
  • Kévin Bouiller,
  • Quentin Lepiller,
  • Lynda Toko and
  • Alix Pierron
  • + 5 authors

21 June 2022

Background. Long-term evolution data of olfactory disorders (OD) in COVID-19 are limited. Method. ANOSVID is a retrospective study in Nord Franche-Comté Hospital (France) that included COVID-19 patients from the first wave. The aim was to desc...

  • Review
  • Open Access
13 Citations
4,894 Views
32 Pages

Xenobiotic Receptors and Their Mates in Atopic Dermatitis

  • Deborah Minzaghi,
  • Petra Pavel and
  • Sandrine Dubrac

29 August 2019

Atopic dermatitis (AD) is the most common inflammatory skin disease worldwide. It is a chronic, relapsing and pruritic skin disorder which results from epidermal barrier abnormalities and immune dysregulation, both modulated by environmental factors....

  • Review
  • Open Access
6 Citations
3,613 Views
23 Pages

Endotyping Chronic Respiratory Diseases: T2 Inflammation in the United Airways Model

  • Pasquale Ambrosino,
  • Giuseppina Marcuccio,
  • Giuseppina Raffio,
  • Roberto Formisano,
  • Claudio Candia,
  • Fabio Manzo,
  • Germano Guerra,
  • Ennio Lubrano,
  • Costantino Mancusi and
  • Mauro Maniscalco

19 July 2024

Over the past 15 years, the paradigm of viewing the upper and lower airways as a unified system has progressively shifted the approach to chronic respiratory diseases (CRDs). As the global prevalence of CRDs continues to increase, it becomes evident...

  • Review
  • Open Access
3,315 Views
21 Pages

24 October 2025

Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by itching, redness, and dryness, significantly impacting the quality of life of affected individuals. With a rising prevalence across diverse demographics, understanding A...

  • Article
  • Open Access
1,067 Views
12 Pages

The Overlooked Burden of Atopic Comorbidities in Eosinophilic Esophagitis: Insights from a Real-Life Comprehensive Multidisciplinary Evaluation

  • Marcella Pesce,
  • Mario Ricchiuti,
  • Elena Cantone,
  • Maddalena Napolitano,
  • Aikaterini Detoraki,
  • Michele Falco,
  • Pierpaolo De Giorgi,
  • Roberto Berni Canani,
  • Mauro Maniscalco and
  • Giovanni Sarnelli

16 October 2025

Background/Objectives: Eosinophilic esophagitis (EoE) is a T2-mediated disease characterized by dysphagia and food impaction. It is often associated with other atopic disorders and is considered a late manifestation of the “atopic march”....

  • Article
  • Open Access
15 Citations
3,460 Views
11 Pages

Medication Adherence to Intranasal Corticosteroids in Allergic Rhinitis Patients with Comorbid Medical Conditions

  • Prempreet Kaur Manjit Singh,
  • Elang Kumaran Krishnan,
  • Norhafiza Mat Lazim,
  • Najib Majdi Yaacob and
  • Baharudin Abdullah

Background: To determine medication adherence to intranasal corticosteroid spray (INCS) among allergic rhinitis (AR) patients with comorbid medical conditions. Methods: A cross-sectional study was conducted. Adults above 18 years old with persistent...