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Keywords = acoustic rhinometry

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13 pages, 895 KB  
Article
Agreement Between Acoustic Rhinometry and Computed Tomography Nasal Cross-Sectional Areas Perpendicular to the Direction of the Airflow
by Aris I. Giotakis, Helen Heppt, Matthias Santer, Martin Pillei and Manuel Berger
Diagnostics 2026, 16(2), 229; https://doi.org/10.3390/diagnostics16020229 - 11 Jan 2026
Viewed by 156
Abstract
Background/Objectives: To thoroughly compare acoustic rhinometry (AR) with computed tomography (CT) cross-sectional areas that are approximately perpendicular to the direction of the nasal airflow (CT-CSA). Methods: We retrospectively examined subjects scheduled for functional nasal surgery, along with preoperative CT and AR. [...] Read more.
Background/Objectives: To thoroughly compare acoustic rhinometry (AR) with computed tomography (CT) cross-sectional areas that are approximately perpendicular to the direction of the nasal airflow (CT-CSA). Methods: We retrospectively examined subjects scheduled for functional nasal surgery, along with preoperative CT and AR. CT-CSAs were assessed in several nasal planes in the first 5 cm of the nasal airway. Area sizes and distances of the CT-CSAs from the columella served to create a CT curve analogous to the AR curve. AR curves were digitized. We examined the correlation and agreement (using the Bland–Altman method) between CT curves and digitized AR curves, as well as between selected CT-CSAs and the first two-encountered AR minimal cross-sectional areas (AR-MCA1 and AR-MCA2). Correlation was investigated by univariate analysis of variance and Pearson’s correlation. Agreement was examined by the Bland–Altman method. Results: In 33 subjects, the correlation of digitized AR with CT was moderate (r = 0.76; p < 0.001). AR, in general, underestimated the actual nasal area by 15%. AR-MCA1 and AR-MCA2 were closest to the CT-CSA of the nasal valve and the incisive canal, respectively. We noted a mainly moderate correlation between the CT-CSA of the nasal valve and AR-MCA1 (all r > 0.59; all p < 0.001) in contrast to the weaker correlations between the CT-CSA of the incisive canal and AR-MCA2. Conclusions: AR may underestimate the actual nasal area by 15%. AR-MCA1 and AR-MCA2 were closest to the CT-CSA of the nasal valve and the incisive canal, respectively. Full article
(This article belongs to the Section Medical Imaging and Theranostics)
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11 pages, 307 KB  
Article
Objective Evaluation of Nasal Obstruction in Cleft Lip and Palate Patients: A Preliminary Study
by Nicolas Pachebat, Jiad N. Mcheik, Maxime Fieux, Valentin Favier, Aurélien Binet, Xavier Dufour and Florent Carsuzaa
J. Pers. Med. 2025, 15(9), 403; https://doi.org/10.3390/jpm15090403 - 1 Sep 2025
Viewed by 974
Abstract
Introduction: Cleft lip and/or palate (CLP) is frequently associated with persistent nasal obstruction, often due to structural deformities unaddressed by primary surgical repair. While subjective assessment tools are commonly used to evaluate nasal patency, they underestimate functional impairment, particularly nasal valve collapse. [...] Read more.
Introduction: Cleft lip and/or palate (CLP) is frequently associated with persistent nasal obstruction, often due to structural deformities unaddressed by primary surgical repair. While subjective assessment tools are commonly used to evaluate nasal patency, they underestimate functional impairment, particularly nasal valve collapse. This study aims to objectively evaluate nasal obstruction and identify its anatomical causes in CLP patients after primary rhinoplasty. Methods: We conducted an observational study involving 21 children aged 8–16 with CLP who had undergone primary cheilorhinoplasty but not secondary nasal surgery. Each participant underwent clinical evaluation, nasal endoscopy, acoustic rhinometry, and active anterior rhinomanometry (AAR), both before and after nasal decongestion. The Nasal Obstruction Symptom Evaluation (NOSE) scale was used to assess subjective symptoms. Obstructive sites were diagnosed based on established criteria combining endoscopic and functional findings. Results: Objective nasal obstruction was identified in 80.9% of patients, with nasal valve collapse observed in 66.7%, most commonly among unilateral and bilateral CLP subtypes. External nasal valve collapse was the predominant form (57.1%), followed by internal valve involvement (38.1%). Notably, the NOSE score did not reliably correlate with the AAR results, underlining the limitations of subjective assessment tools. Structural anomalies such as septal deviation (52.5%) and turbinate hypertrophy (23.8%) were also prevalent. Conclusions: This study highlights nasal valve collapse as a major, underrecognized contributor to persistent nasal obstruction in CLP patients after primary repair. Objective assessment methods like AAR and targeted endoscopy should be routinely integrated into secondary rhinoplasty planning. These findings advocate for a personalized approach to secondary nasal reconstruction in CLP patients, integrating objective functional data into surgical planning. Such strategies align with personalized medicine principles by tailoring interventions to individual anatomical and physiological characteristics. Full article
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11 pages, 3788 KB  
Article
Aesthetic and Functional Outcomes of Combined Use of Extended Spreader Graft and Septal Extension Graft
by Yung Jin Jeon, Tae-Hun Lee, Yeon-Hee Joo and Sang-Wook Kim
Life 2025, 15(4), 546; https://doi.org/10.3390/life15040546 - 26 Mar 2025
Viewed by 2955
Abstract
Deviation of the cartilaginous midvault and caudal nasal septum can cause both aesthetic misalignment and functional impairment of the nasal valves. This study explores the technical considerations and outcomes of combining extended spreader graft and septal extension graft in septorhinoplasty to correct these [...] Read more.
Deviation of the cartilaginous midvault and caudal nasal septum can cause both aesthetic misalignment and functional impairment of the nasal valves. This study explores the technical considerations and outcomes of combining extended spreader graft and septal extension graft in septorhinoplasty to correct these deviations. A retrospective analysis of 24 patients who underwent primary septorhinoplasty between January 2022 and July 2023, performed by a single surgeon, was conducted with a mean follow-up of 11.28 months. Unilateral or bilateral extended spreader grafts and septal extension grafts were placed on the concave side of the deviation. Clinical charts, surgical records, standardized photographs, and acoustic rhinometry data were analyzed for objective and subjective outcomes. Among 24 patients (21 males, 3 females; mean age 35.2 ± 15.0 years), successful correction of C-shaped nasal deviation was achieved with no significant complications observed in the short-term follow-up (p < 0.0001). Functional improvements were observed in nasal volume and minimum cross-sectional area (p < 0.0001). Most patients reported high satisfaction with both functional and aesthetic outcomes. Compared to traditional septorhinoplasty techniques, this combined approach offers a structured method to address both cosmetic and functional concerns. These findings suggest that the combined use of extended spreader grafts and septal extension grafts offers a promising approach for addressing both cosmetic and functional concerns in septorhinoplasty. Full article
(This article belongs to the Section Medical Research)
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10 pages, 3697 KB  
Article
Nasal Patency in Sitting, Supine, and Prone Positions in Individuals with and without Allergic Rhinitis
by Yun-Ting Wang, Yao-Te Tsai, Cheng-Ming Hsu, Ming-Shao Tsai, Hsin-Yi Tsai and Geng-He Chang
Life 2023, 13(5), 1226; https://doi.org/10.3390/life13051226 - 22 May 2023
Cited by 4 | Viewed by 5366
Abstract
(1) Background: Physiological changes in nasal patency in response to posture contribute to sleep-related problems. Previously, we reported that the supine and prone positions cause a significant decrease in nasal patency in subjective and objective assessments of healthy individuals. Therefore, we conducted a [...] Read more.
(1) Background: Physiological changes in nasal patency in response to posture contribute to sleep-related problems. Previously, we reported that the supine and prone positions cause a significant decrease in nasal patency in subjective and objective assessments of healthy individuals. Therefore, we conducted a study to evaluate the effect of posture on nasal patency in patients with allergic rhinitis (AR); (2) Methods: The present study comprised 30 patients diagnosed with AR and 30 healthy subjects without nasal disease (non-AR). Changes in nasal patency were evaluated in the sitting, supine, and prone positions. We used the visual analog scale to evaluate subjective nasal blockage. Acoustic rhinometry and endoscopy were used to objectively measure changes in nasal patency; (3) Results: In the non-AR group, the prone position had a significant effect on subjective nasal blockage compared with the sitting position, with significant decreases in the minimal cross-sectional area (mCSA) measured by acoustic rhinometry. Furthermore, endoscopy demonstrated a significantly increased inferior turbinate hypertrophy in the non-AR group. In the AR group, there was no statistical difference in subjective nasal blockage symptoms between the different positions. However, in objective examinations (acoustic rhinometry and endoscopy), the prone position showed significantly decreased nasal patency; (4) Conclusions: In patients with AR, subjective nasal blockage did not significantly increase in the supine or prone position. Endoscopy demonstrated increased inferior turbinate hypertrophy in supine and prone positions resulting in a significant reduction in nasal cavity mCSA, indicating an objective reduction in nasal patency. Full article
(This article belongs to the Section Physiology and Pathology)
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11 pages, 1732 KB  
Article
Influence of Age and Gender on Nasal Airway Patency as Measured by Active Anterior Rhinomanometry and Acoustic Rhinometry
by Jing-Jie Wang, Yi-Fang Chiang and Rong-San Jiang
Diagnostics 2023, 13(7), 1235; https://doi.org/10.3390/diagnostics13071235 - 24 Mar 2023
Cited by 8 | Viewed by 2737
Abstract
In this study, we aimed to investigate the influences of age and gender on nasal airway patency, as measured by both active anterior rhinomanometry (AAR) and acoustic rhinometry (AR). The nasal airway patency of healthy subjects was evaluated using AAR and AR. In [...] Read more.
In this study, we aimed to investigate the influences of age and gender on nasal airway patency, as measured by both active anterior rhinomanometry (AAR) and acoustic rhinometry (AR). The nasal airway patency of healthy subjects was evaluated using AAR and AR. In AAR, the subjects generated airflow actively through inspiration and expiration in repetitions of 10, while nasal patency was measured at an inspiratory and expiratory reference pressure of 75 Pa. In AR, we assessed the geometry of the nasal cavity through the analysis of sound waves reflected from the nasal cavities in order to measure both cross-sectional areas and nasal volumes. The subjects were divided by gender, with all males and females then grouped by ages of 20–39 years, 40–59 years and ≥60 years. There were 40 subjects in each group. The mean resistance measured by AAR and the cross-sectional areas and nasal volumes measured by AR were not different between the different age groups; however, the cross-sectional areas and nasal volumes were found to be lesser in females than in males. Our results showed that nasal airway patency was not affected by age, while females were shown to have wider nasal passages than males. Full article
(This article belongs to the Special Issue Advances in the Diagnosis and Management of ENT Diseases)
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10 pages, 904 KB  
Article
Clinical Characteristics of Patients with Dental Malocclusion: An Otolaryngologic Perspective
by Shin Hyuk Yoo, Ji Hyeok Choi and Ji-Hun Mo
J. Clin. Med. 2022, 11(21), 6318; https://doi.org/10.3390/jcm11216318 - 26 Oct 2022
Cited by 4 | Viewed by 2224
Abstract
Purpose: Allergic rhinitis (AR), which is a major cause of upper airway obstruction, may affect the development of the dental malocclusion. This retrospective study was aimed to investigate association between AR and dental malocclusion in otolaryngologic perspectives. Methods: Patients (n = 217) [...] Read more.
Purpose: Allergic rhinitis (AR), which is a major cause of upper airway obstruction, may affect the development of the dental malocclusion. This retrospective study was aimed to investigate association between AR and dental malocclusion in otolaryngologic perspectives. Methods: Patients (n = 217) referred to the otolaryngology department before initiating orthodontic treatment were recruited. The frequency and severity of AR symptoms, sinonasal outcome test (SNOT-22) scores, physical examination findings, acoustic rhinometry results, and treatment modalities were retrospectively assessed. Patients with positive skin prick test findings (SPT) (n = 173; orthodontic group) were compared with age- and sex-matched patients being treated for AR (AR group). Results: We found that 76.5% of the enrolled patients had subjective nasal symptoms, and 93.1% patients showed abnormal physical examination findings such as inferior turbinate hypertrophy (82.0%), adenotonsillar hypertrophy (31.8%), or deviated nasal septum (7.4%). The 173 (79.7%) patients with positive SPT results exhibited a significantly higher incidence of rhinorrhoea, sneezing, and inferior turbinate hypertrophy compared to those with negative SPT results. The proportion of patients who underwent pharmacological or surgical treatments was significantly higher among patients with nasal obstruction (92.0%) than among patients without nasal obstruction (36.9%). The frequency and mean visual analogue symptom scores for nasal obstruction, rhinorrhoea, and sneezing, as well as all SNOT-22 domain scores, were significantly higher in the AR group than in the orthodontic group. The minimal cross-sectional area measured with acoustic rhinometry showed no significant difference between groups. Conclusion: Patients with dental malocclusion had a high SPT (+) rate and a high prevalence of structural abnormalities of the upper airway. The early detection and treatment of subclinical AR, other rhinological problems, and structural abnormalities of the upper airway in patients with malocclusion may help us manage malocclusion from an otolaryngologic perspective. Full article
(This article belongs to the Special Issue Allergic Rhinitis: Epidemiology, Prevention and Clinical Treatment)
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9 pages, 1764 KB  
Article
Correlations between Peak Nasal Inspiratory Flow, Acoustic Rhinometry, 4-Phase Rhinomanometry and Reported Nasal Symptoms
by Giancarlo Ottaviano, Alfonso Luca Pendolino, Bruno Scarpa, Miriam Torsello, Daniele Sartori, Enrico Savietto, Elena Cantone and Piero Nicolai
J. Pers. Med. 2022, 12(9), 1513; https://doi.org/10.3390/jpm12091513 - 15 Sep 2022
Cited by 13 | Viewed by 3658
Abstract
Background: Rhinomanometry, acoustic rhinometry (AR) and peak nasal inspiratory flow (PNIF) are popular methods for nasal patency evaluation. The aim of the present study was to compare these three methods with the reported nasal symptoms to determine the best diagnostic tool to assess [...] Read more.
Background: Rhinomanometry, acoustic rhinometry (AR) and peak nasal inspiratory flow (PNIF) are popular methods for nasal patency evaluation. The aim of the present study was to compare these three methods with the reported nasal symptoms to determine the best diagnostic tool to assess nasal obstruction. Methods: 101 subjects were evaluated using PNIF, 4-phase rhinomanometry (4PR), AR, Visual Analogue Scale for nasal obstruction (VAS-NO) and Sino-Nasal Outcome Test (SNOT-22). Correlations among PNIF, 4PR, AR, VAS-NO and SNOT-22 were obtained. Results: VAS-NO and SNOT-22 were moderately correlated with each other (r = 0.54, p < 0.001). 4PR was moderately correlated with PNIF (r = –0.31, p = 0.0016) and AR (r = –0.5, p < 0.001). VAS-NO was mildly correlated with PNIF (r = –0.29, p = 0.0034). SNOT-22 was moderately correlated with PNIF (r = –0.31, p = 0.0017). After dividing the population into symptomatic and asymptomatic subjects, based on their VAS-NO score, the former showed significantly lower PNIF values (p = 0.009) and higher 4PR values (p = 0.013) compared to the latter ones. Conclusion: PNIF and 4PR showed a significant moderate correlation with each other, but PNIF showed a significant correlation (weak-moderate) with the reported nasal symptom scores. Full article
(This article belongs to the Section Methodology, Drug and Device Discovery)
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8 pages, 244 KB  
Article
Acoustic Rhinometry in the Evaluation of Nasal Lysine Aspirin Challenge
by Maciej Kupczyk, Izabela Kupryś-Lipińska, Małgorzata Bocheńska-Marciniak and Piotr Kuna
Adv. Respir. Med. 2010, 78(2), 103-111; https://doi.org/10.5603/ARM.27735 - 19 Mar 2010
Cited by 1 | Viewed by 710
Abstract
Background: Nasal lysine aspirin (Lys-ASA) challenge is an alternative to oral and bronchial challenges in the diagnosis of hypersensitivity to acetylsalicylic acid (ASA) and other non-steroid anti-inflammatory drugs (NSAIDs). The aim of the study was to evaluate the sensitivity and specificity of [...] Read more.
Background: Nasal lysine aspirin (Lys-ASA) challenge is an alternative to oral and bronchial challenges in the diagnosis of hypersensitivity to acetylsalicylic acid (ASA) and other non-steroid anti-inflammatory drugs (NSAIDs). The aim of the study was to evaluate the sensitivity and specificity of acoustic rhinometry as an objective method of evaluation of nasal Lys-ASA challenge. Material and methods: We enrolled 20 patients with ASA-induced asthma confirmed by oral challenge (ASA-S group), 5 patients with allergic rhinitis without hypersensitivity to NSAIDs, and 5 healthy individuals (ASA-NS group). All the subjects underwent challenge with placebo (0.9% NaCl) or 14.4 mg of Lys-ASA applied in a spray into both nostrils (total dose: 16 mg of ASA). Measurements of nasal volume bilaterally were performed with an acoustic rhinometer before and 1, 2, 4, and 24 hours after the challenge. For further calculations we used the sum of both nasal volumes at 2 to 5 cm from the nostrils. Results: The mean total nasal volume in the AIA group before and 1, 2, 4, and 24 hours after the challenge was 7.75, 6.21, 7.11, 7.12, and 7.24 cm3 following placebo, respectively, and 7.24, 5.77, 6.31, 6.27, and 6.98 cm3 following Lys-ASA, respectively (p = 0.048 and p = 0.02 at 2 and 4 hours, Lys-ASA vs. placebo, Wilcoxon test). With the cutoff value of nasal volume reduction of 10%, the test sensitivity was 70%, the specificity was 60%, the positive predictive value was 77.78%, and the negative predictive value was 50% at 1 hour after the challenge. Conclusions: Acoustic rhinometry with the measurement of nasal volume at 2 to 5 cm from the nostrils proved insufficiently sensitive or specific to be used as the sole method for evaluation of nasal Lys-ASA challenge. Full article
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