Search Results (36)

Chinese local governments mandate public buildings to maintain a cooling set point temperature (SPT ≥ 26 °C). To explore how thermal history and air conditioner use behavior under different cooling SPT modes influence health, an experimental study and field investigation was carried out in split air-conditioned office buildings in China’s cold climate regions. Two categories were established based on energy policy: the H group (SPT ≥ 26 °C) and the L group (SPT < 26 °C). The results showed that L group subjects experienced longer, colder, and higher CO₂/formaldehyde exceedance rate exposures in air-conditioned environments, demonstrating greater reliance on air conditioners, although indoor air quality satisfaction showed no significant difference between groups. Air quality perception demonstrates long-term adaptation to indoor air temperature and CO₂. Compared with the high SPT mode, the adverse influences and mechanisms of the low SPT mode on health are as follows: making people adapt to cold environments due to colder thermal history and inducing pathological adaptation cycles, thus promoting strong reliance on the air-conditioned environment. This leads to a substantial increase in air conditioner use time, thereby increasing the severity of sick building syndrome (SBS), indoor pollutants, formaldehyde carcinogenic risk, and desensitized air quality perception. China’s government should systematically enhance the enforcement of SPT-related policies. Full article

Herein, we address the peculiar lack of scientific reporting on odor potent chloroanisoles (CAs) in the built environment. We have searched and critically examined sources beyond peer-reviewed scientific journals, namely research conferences, parliamentary records, newspaper articles, and cartoons. We provide evidence that CAs evolved on a large scale in Swedish buildings in the early 1970s and evoked a typical sticky malodor that was attributed to mold and gave rise to the term “mold houses”. The term first appeared in Swedish newspapers in 1978, and the media attention increased rapidly. The malodorous “mold houses” reached the Swedish parliament and led to economic compensation for afflicted homeowners. The “mold houses” became “sick houses” as researchers, predominantly from Sweden, introduced and became world leaders on the “sick buildings syndrome” (SBS). Researchers became aware of the CAs but did not mention them in peer-reviewed articles, just as they did not mention a well-known source of the sticky malodor, namely, legacy preserved wood where CAs were formed through microbial methylation of toxic chlorophenols (CPs). Thus, the mold story from the early 1970s was maintained and prevented the malodorous CAs from becoming recognized as indicators of the presence of hazardous CPs. Our study is the first to report the impact of an indoor malodor, not only on a few people, but on society. Full article

Sick building syndrome (SBS) poses a significant challenge in hospital settings, adversely affecting staff health, operational efficiency, and environmental quality. This study aims to investigate the prevalence and risk factors of SBS among medical staff in Chinese hospitals, advancing the literature by pinpointing actionable environmental and psychological factors tailored to this occupational group within China’s distinct regional context. A survey questionnaire was administered to 615 medical staff members across seven private hospitals located in the eastern coastal region of China. Data were collected using structured questionnaires. The survey encompassed 27 factors across four aspects, with respondents being asked to self-assess the severity of four types of SBS symptoms (never, rarely, occasionally, often). Multivariable binary logistic regression analysis was carried out to identify factors associated with SBS, based on odds ratios (OR) with a significance level of p < 0.05. The prevalence rates for skin symptoms, mucosal symptoms, and general symptoms were 32.8%, 61%, and 71.1%, respectively. Gender, psychological mood, visibility of water systems and greenery from the workspace, outdoor noise environment, indoor air quality, indoor natural lighting, department of occupancy, design of workspace, cleanliness, and control over the indoor environment (temperature, lighting) were identified as risk factors related to SBS symptoms. These findings underscore the critical role of modifiable building design and psychological factors in SBS occurrence, offering a novel perspective on hospital-specific risks in China compared to global studies. Enhancing indoor and outdoor environments—through increased greenery, noise reduction, improved air quality, better lighting, and greater environmental control—emerges as a vital strategy to mitigate SBS, with implications for hospital management and staff well-being. Full article

Background: The role of the indoor microbiome in sick building syndrome (SBS) is well-recognized, yet prior studies have been limited to single-center analyses, limiting a broader understanding and applicability of their findings. Methods: We conducted a multicenter indoor microbiome and metabolome investigation for SBS, involving 1139 middle school students across three regions in Malaysia (Johor Bahru, Terengganu, and Penang). Using high-throughput amplicon sequencing and untargeted LC-MS, indoor microbiome and metabolites were characterized from classroom dust samples. Results: The study found that the prevalence of SBS symptoms was high across all three centers (51.0% to 54.6%). Environmental characteristics, including indoor NO₂ and CO₂ concentrations and total weight of indoor dust, were positively associated with SBS (p < 0.01, linear regression). Curtobacterium in Terengganu was negatively associated with SBS, and Clostridium perfringens in Johor Bahru was positively associated with SBS (p < 0.01, FDR < 0.05). Whereas all identified fungal taxa, including an uncharacterized uc_f_Auriculariaceae_sp., Duportella kuehneroides, and Wallemia mellicola, were positively associated with SBS (p < 0.01, FDR < 0.05) in Johor Bahru and Terengganu. Mediation analysis revealed that the adverse health effects of NO₂ on SBS were partially mediated by the increased abundance of uc_f_Auriculariaceae_sp. (p < 0.05, total effect mediated 51.40%). Additionally, potential protective metabolites (S-adenosylmethionine, N-acetylserotonin, sphinganine, 4-hydroxy-2-quinolone, and (2E,4Z,8E)-Colneleic acid) were mainly derived from environmental microorganisms, conferring protective effects against nasal symptoms and tiredness. In contrast, synthetic chemicals were associated with higher SBS symptoms, inducing eye and nasal symptoms. Conclusions: This study emphasizes both the significance of fostering a balanced indoor microbiome/metabolite and the necessity to reduce exposure to deleterious substances, providing new insights for future targeted intervention strategies. Full article

Quarantine policies during the coronavirus disease 2019 (COVID-19) pandemic prolonged time spent at home, leading to an unintended occurrence of sick building syndrome (SBS) symptoms. The aim of this study was to investigate the prevalence of SBS symptoms among residents in Suzhou, China, during the COVID-19 pandemic. A questionnaire survey was conducted online from February to May 2022. A total of 442 adults were included in this study. The prevalence of SBS symptoms was much higher during the COVID-19 pandemic, and the proportions of general, mucosal, and skin symptoms were 59.3%, 45.5% and 49.1%, respectively. The influences of building characteristics, occupant lifestyle, indoor environment and perception of indoor environment were analysed using a multivariate logistic regression model. Neighbourhood pollutant sources, older residences, non-ownership and humidity indicators were significant risk factors for SBS symptoms. Frequent use of air fresheners was significantly associated with general (adjusted odds ratio (AOR): 4.9, 95% confidence interval (CI: 2.4–10.0), mucosal (AOR: 5.3, 95% CI: 2.4–11.5), and skin symptoms (AOR: 4.6, 95% CI: 1.6–13.1), while the use of disinfectants was significantly correlated with skin symptoms (AOR: 4.0, 95% CI: 1.5–10.7). Residents’ perception of an uncomfortable indoor environment was a significant predictor of general (AOR: 2.2, 95% CI: 1.2–4.0) and mucosal symptoms (AOR: 3.1, 95% CI: 1.6–6.0). The use of air cleaners can reduce the prevalence of general symptoms. An important finding of this study is that the psychological impact of staying at home for a long time was associated with general symptoms (AOR: 1.3, 95% CI: 1.1–1.7), which means that attention should also be paid to the mental health of residents during the COVID-19 pandemic. Although the quarantine period has now ended, our results can still serve as a reference for the impact of the indoor environment on the health of people with SBS, especially for those who stay at home for a long time, such as the elderly. Full article

Indoor air quality (IAQ) directly affects human health. The increase in PM and CO₂ concentration indoors caused an increase in the prevalence of sick building syndrome (SBS) symptoms. Plants could contribute to reducing particulate matter (PM) and CO₂. This study identifies the most efficient evergreen plant species for improving indoor air quality by assessing the ability of five different indigenous Korean evergreen plant species to reduce PM and CO₂ and regulate humidity and temperature under indoor environmental conditions in acrylic chambers. The clean air delivery rates (CADR) were calculated to evaluate the efficacy of plants in reducing PM and CO₂. We assessed the performance of removing the five study plants on PM₁ (~0.68–3.01 m³/h/leaf area), PM_2.5 (~0.73–3.08 m³/h/leaf area), PM₁₀ (~0.67–3.04 m³/h/leaf area), and CO₂ (~0.48–1.04 m³/h/leaf area). The species Ilex pedunculosa, Pittosporum tobira, and Gardenia jasminoides were the most effective at reducing PM. The CADR of CO₂ also differed among the five plant species and corresponded to their photosynthetic rate. Viburnum odoratissimum var. awabuki, which had the high photosynthetic rate, was most effective at reducing CO₂. By contrast, PM reduction was correlated with plant leaf structure. Plants with a high leaf density can accumulate more PM. The plants were also able to control temperature and humidity. The average temperature of the control chamber was higher, and the humidity was lower than that of the plant chambers. In this study, the five evergreen species effectively reduced air pollutants and can be used to improve IAQ. Full article

This research investigates different facets of indoor air quality and the corresponding health symptoms within a retail environment. Formaldehyde, classified as a Group B carcinogenic substance, was found within safe limits indoors, primarily originating from surface coatings, flooring products, textiles, and furniture. Monoterpenes, lactic acid, and particulate matter levels were also assessed, with varying indoor–outdoor ratios. Notably, we identified a relatively low concentration of PM2.5, possibly influenced by enhanced cleaning practices during the COVID-19 pandemic. Symptom assessment revealed that many young workers experienced work-related symptoms, notably fatigue, nose-, throat-, and skin-related issues, aligning with previous findings. Although we could not conclusively link these symptoms to sick building syndrome (SBS) or formaldehyde exposure, it underscores the importance of further investigation. Notably, we observed no gender-based differences in symptom prevalence, but this study’s limited size requires caution in generalization. This study contributes to understanding indoor air quality and associated symptoms in an economically significant sector, emphasizing the need for continued research, especially considering the potential impact on workforce health in the broader context. Full article

Paper is in the scope of moisture-related problems which are connected with mold threat in buildings, sick building syndrome (SBS) as well as application of electronic nose for evaluation of different building envelopes and building materials. The machine learning methods used to analyze multidimensional signals are important components of the e-nose system. These multidimensional signals are derived from a gas sensor array, which, together with instrumentation, constitute the hardware of this system. The accuracy of the classification and the correctness of the classification of mold threat in buildings largely depend on the appropriate selection of the data analysis methods used. This paper proposes a method of data analysis using Principal Component Analysis, metric multidimensional scaling and Kohonen self-organizing map, which are unsupervised machine learning methods, to visualize and reduce the dimensionality of the data. For the final classification of observations and the identification of datasets from gas sensor arrays analyzing air from buildings threatened by mold, as well as from other reference materials, supervised learning methods such as hierarchical cluster analysis, MLP neural network and the random forest method were used. Full article

Indoor air pollution has become a pressing issue in the United Arab Emirates (UAE) due to poor ventilation, inadequate airtightness, and using chemicals in building materials. Accordingly, the UAE is currently experiencing more cases of sick building syndrome (SBS) than any other country. This study aims to assess the effectiveness of the bake-out strategy in reducing indoor air pollutants in a new apartment building in the UAE. The study evaluated a reduction in toluene (C₇H₈), ethylbenzene (C₈H₁₀), xylene (C₈H₁₀), styrene (C₈H₈), and formaldehyde (HCHO) at room temperature and relative humidity. The airtight unit without winter bake-out had higher indoor concentrations of hazardous chemicals than the ventilated units, and the emission of dangerous substances increased with temperature. Moreover, harmful chemicals were only effectively reduced with ventilation times of at least seven days after the heating period. The release rate of contaminants after the bake-out was lower than before. The indoor concentration of hazardous chemicals was lower when bake-out and mechanical ventilation were combined, resulting in a reduction of 92.8% of HCHO. Furthermore, units with a certain amount of ventilation maintained a low indoor pollutant concentration, regardless of whether a bake-out was performed. Full article

This study investigated the indoor environment quality (IEQ) of eight office buildings of interest due to: (a) their location at the region of Western Macedonia, Greece, which is an area characterized by aggravated air quality and is currently in a transition phase because of changes in the energy production strategy to reduce the use of lignite as an energy fuel; and (b) the survey’s timing, characterized by new working conditions implemented during the COVID-19 pandemic period. In-site measurements were performed to identify the indoor air pollutants to which the occupants were exposed, while questionnaires were collected regarding the participants’ perception of the working environment conditions, indoor air quality, and health symptoms. The statistical analysis results showed that the most-reported health symptoms were headache, dry eyes, and sneezing. The acceptance of new working conditions showed a significant correlation with their overall comfort and health perception. Occupants in offices with higher pollutant concentrations, such as NO₂, benzene and toluene, were more likely to report health symptoms. The evaluation of the plausible health risks for the occupants of the buildings with carcinogenic and no-cancer models showed that health problems could exist despite low pollutant concentration levels. Full article

Teachers and students work and study in classrooms for long durations. The indoor environment directly affects the health and satisfaction of teachers and students. To explore the performance differences between green buildings, conventional buildings, and retrofitted buildings in terms of their indoor environment, occupant satisfaction, and sick building syndrome (SBS), as well as the correlation between these different aspects, three university teaching buildings were selected in hot summer and cold winter regions in China. These included a green building (GB), a retrofitted building (RB), and a conventional building (CB). Long-term indoor environment monitoring and point-to-point measurements were conducted during the transition season and winter and the indoor environment, satisfaction, and SBS in the three buildings were compared. A sample of 399 point-to-point questionnaires was collected. A subjective-objective indoor environmental quality (IEQ) evaluation model for schools in China was established, covering satisfaction and the indoor environment. The results showed that the compliance rate of the indoor environment in the GB and RB was generally superior to that of the CB. The overall satisfaction was the highest for the GB, followed by the CB, and then the RB. The GB had the highest overall indoor environment quality score, followed by the RB and then the CB. The occurrence of SBS was lowest in the CB, followed by the GB, and then the RB. It was determined that the design of natural ventilation should be improved and that building users should be given the right to autonomous window control and temperature control. To reduce the occurrence of SBS symptoms, attention should be paid to the control of temperature and CO₂ concentration. To improve learning efficiency, it suggests reducing indoor CO₂ concentrations and improving desktop illuminance. This study provides a reference for improving the indoor environment and health performance of existing university teaching buildings. Full article

According to UAE Health Ministry and Dubai Healthcare City reports, 15% of Dubai residents have a chronic respiratory disease such as asthma. Moreover, 90% of the 150,000 patients at Al Ain Hospital suffered from upper respiratory tract respiratory diseases, bronchitis, or asthma. Sick Building Syndrome (SBS) has emerged as a social problem in the United Arab Emirates (UAE). The Dubai Municipality regulates Indoor Air Quality (IAQ) with strict stipulations before moving in, but they are relatively passive about regulations related to healthy living. This paper aims to explore the actual state of perception of the IAQ from townhouse residents in Dubai, UAE. The characteristics of the resident’s perceptions of the IAQ are identified, and the influential factors affecting residents’ perceptions of IAQ are extracted. As a methodology, the survey was conducted on four townhouse projects in Dubai from December 2021 to January 2022. A total of 114 copies were distributed, and 98 documents were used. Analysis of the survey data was processed using IBM SPSS Statistics 26.0. The results showed a statistically significant correlation between the cognitive and anxiety levels of SBS with the presence or absence of experience. It was statistically confirmed that the most influential factors were the age of the children and the occupancy time of housewives and children. This is because of the perception that wives who spend a relatively long time in the house and their young children are exposed to indoor air pollution for a long period of time and are easily affected by this influence on the concerns about young children about SBS. Ninety-five percent of the respondents answered that they knew more than average about SBS, indicating a very high level of awareness. As for the degree of anxiety, 87.0% of the respondents felt higher levels of anxiety than usual. However, most of them did not know or were indifferent to the understanding of the air quality improvement methods. The awareness of actual contents was lower than that of residents who assessed that they knew about SBS. Full article

Sick building syndrome (SBS) is the term used to describe the medical condition in which people in a building suffer from symptoms of illnesses for no apparent reason. SBS was found to be associated with indoor air quality (IAQ) but there are a variety of determinants (buildings, in particular). Identifying and controlling factors related to SBS is crucial for improving worker health and efficiency. A cross-sectional study was conducted to investigate (1) the prevalence of respiratory symptoms and skin SBS and (2) their associations with IAQ among office workers in administrative offices in an academic medical institute. A self-reporting questionnaire assessing the worker’s characteristics, working conditions, and perception of working environments was used. The building assessment was via a walk-through survey and IAQ measurement. Of 290 office workers, 261 (90%) in 25 offices of 11 buildings took part in the survey. The highest prevalence of SBS was nasal symptoms (25.3%). We found that to reduce the risk of SBS, optimal air temperature levels in air-conditioned offices should be lower than 23 °C, with relative humidity between 60% and 70%. Lowering indoor CO₂ levels below 700 ppm may be indicative of adequate ventilation to prevent SBS by reducing worker discomfort and indoor contaminants (e.g., formaldehyde). Full article

Submicroscopic nanoparticles (NPs) in air have received much attention due to their possible effects on health and wellbeing. Adverse health impacts of air pollution may not only be associated with level of exposure, but also mediated by the perception of the pollution and by beliefs of the exposure being hazardous. The aim of this study was to test a model that describes interrelations between NP pollution, perceived air quality, health risk perception, stress, and sick building syndrome. In the NanoOffice study, the level of NPs was measured and a survey on health risk perception was conducted among 260 employees in twelve office buildings in northern Sweden. Path analyses were performed to test the validity of the model. The data refute the model proposing that the NP exposure level significantly influences stress, chronic diseases, or SBS symptoms. Instead, the perceived exposure influences the perceived risk of NP, and the effect of perceived exposure on SBS and chronic disease is mediated by stress. There was little concern about nanoparticles, despite relatively high levels in some facilities. Perceived pollution and health risk perception may explain a large part of the environmentally induced symptoms and diseases, particularly in relatively low levels of pollution. The research results raise important questions on the physiologically or psychologically mediated health effects of air pollution. Full article

At present, with more and more attention paid to the impact of buildings on the health and well-being of occupants, sick building syndrome (SBS) has become a global concern. Since the introduction of SBS by the World Health Organization (WHO) in 1983, thousands of research literatures have been published in this field. This paper systematically arranges knowledge development of SBS through bibliometric analysis, exploring the most influential countries, institutions, journals and scholars, as well as the main subject categories and keywords. Main path analysis (MPA) was used to list development trajectory under inheritance relationship of SBS knowledge, including symptom analysis, risk factors of SBS and the improved impact of ventilation on SBS and productivity. Furthermore, it is an emerging research trend to propose SBS solution in the building design stage. Full article