Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (39)

Search Parameters:
Keywords = SAD phasing

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
12 pages, 301 KiB  
Article
Loneliness and Mental Health Disorders in Older Adults Living in Portugal During the COVID-19 Pandemic: A Cross-Sectional Study
by Odete Araújo, Lia Sousa, Francisco Sampaio, Cláudia Rodrigues, Nadine Correia Santos, Carlos Sequeira and Laetitia Teixeira
Healthcare 2025, 13(13), 1483; https://doi.org/10.3390/healthcare13131483 - 20 Jun 2025
Viewed by 1159
Abstract
Background/Objectives: The COVID-19 pandemic has had a profound impact on the mental health of the general population, particularly older adults. This study aimed to explore the association between loneliness and mental health disorders in this demographic during the pandemic. Methods: A [...] Read more.
Background/Objectives: The COVID-19 pandemic has had a profound impact on the mental health of the general population, particularly older adults. This study aimed to explore the association between loneliness and mental health disorders in this demographic during the pandemic. Methods: A cross-sectional survey was conducted in Portugal using data from the Survey of Health, Ageing and Retirement in Europe (SHARE) database between June and August 2020, during the COVID-19 pandemic (Wave 8 COVID-19 Survey), using computer-assisted telephone interviews. Results: The final sample included 836 participants, with 387 (46.4%) men and a mean age of 74.5 years (SD = 6.7). Mental health indicators revealed that 441 (52.1%) reported feelings of nervousness, 384 (45.3%) experienced sadness or depression, 349 (41.2%) encountered sleeping difficulties, and 280 (33.1%) reported experiencing loneliness often or some of the time. Increased feelings of loneliness were notably associated with women in poorer health, those with heightened fear of falling, dizziness, fatigue, anxiety, depression, and concurrent health and sleep issues. Age and medication use did not significantly impact feelings of loneliness. Conclusions: The findings highlight a potential association between adverse mental health outcomes among older adults during the initial phase of the pandemic. Future research, employing longitudinal research designs, is warranted to explore these relationships more rigorously, in a post-pandemic context, and to inform effective intervention development and strategies to prevent mental health problems within this vulnerable population. Full article
(This article belongs to the Special Issue Mental Health in Older People)
Show Figures

Figure 1

12 pages, 3508 KiB  
Article
Improvement of the Cross-Scale Multi-Feature Stereo Matching Algorithm
by Nan Chen, Dongri Shan and Peng Zhang
Appl. Sci. 2025, 15(11), 5837; https://doi.org/10.3390/app15115837 - 22 May 2025
Viewed by 371
Abstract
With the continuous advancement of industrialization and intelligentization, stereo-vision-based measurement technology for large-scale components has become a prominent research focus. To address weak-textured regions in large-scale component images and reduce mismatches in stereo matching, we propose a cross-scale multi-feature stereo matching algorithm. In [...] Read more.
With the continuous advancement of industrialization and intelligentization, stereo-vision-based measurement technology for large-scale components has become a prominent research focus. To address weak-textured regions in large-scale component images and reduce mismatches in stereo matching, we propose a cross-scale multi-feature stereo matching algorithm. In the cost-computation stage, the sum of absolute differences (SAD), census, and modified census cost aggregation are employed as cost-calculation methods. During the cost-aggregation phase, cross-scale theory is introduced to fuse multi-scale cost volumes using distinct aggregation parameters through a cross-scale framework. Experimental results on both benchmark and real-world datasets demonstrate that the enhanced algorithm achieves an average mismatch rate of 12.25%, exhibiting superior robustness compared to conventional census transform and semi-global matching (SGM) algorithms. Full article
(This article belongs to the Special Issue Advances in Computer Vision and Digital Image Processing)
Show Figures

Figure 1

18 pages, 29962 KiB  
Article
Eliciting Emotions: Investigating the Use of Generative AI and Facial Muscle Activation in Children’s Emotional Recognition
by Manuel A. Solis-Arrazola, Raul E. Sanchez-Yanez, Ana M. S. Gonzalez-Acosta, Carlos H. Garcia-Capulin and Horacio Rostro-Gonzalez
Big Data Cogn. Comput. 2025, 9(1), 15; https://doi.org/10.3390/bdcc9010015 - 20 Jan 2025
Viewed by 2244
Abstract
This study explores children’s emotions through a novel approach of Generative Artificial Intelligence (GenAI) and Facial Muscle Activation (FMA). It examines GenAI’s effectiveness in creating facial images that produce genuine emotional responses in children, alongside FMA’s analysis of muscular activation during these expressions. [...] Read more.
This study explores children’s emotions through a novel approach of Generative Artificial Intelligence (GenAI) and Facial Muscle Activation (FMA). It examines GenAI’s effectiveness in creating facial images that produce genuine emotional responses in children, alongside FMA’s analysis of muscular activation during these expressions. The aim is to determine if AI can realistically generate and recognize emotions similar to human experiences. The study involves generating a database of 280 images (40 per emotion) of children expressing various emotions. For real children’s faces from public databases (DEFSS and NIMH-CHEFS), five emotions were considered: happiness, angry, fear, sadness, and neutral. In contrast, for AI-generated images, seven emotions were analyzed, including the previous five plus surprise and disgust. A feature vector is extracted from these images, indicating lengths between reference points on the face that contract or expand based on the expressed emotion. This vector is then input into an artificial neural network for emotion recognition and classification, achieving accuracies of up to 99% in certain cases. This approach offers new avenues for training and validating AI algorithms, enabling models to be trained with artificial and real-world data interchangeably. The integration of both datasets during training and validation phases enhances model performance and adaptability. Full article
(This article belongs to the Special Issue Perception and Detection of Intelligent Vision)
Show Figures

Figure 1

9 pages, 2049 KiB  
Article
Enhancement of Sulfur Autotrophic Denitrification by Solid-State Carbon Source PHBV for Nitrate Removal of Aquaculture Wastewater
by Boning Pan and Ligang Xu
Processes 2025, 13(1), 265; https://doi.org/10.3390/pr13010265 - 17 Jan 2025
Cited by 1 | Viewed by 1081
Abstract
The aim of this study was to evaluate the effect of a solid slow-release carbon source (3-hydroxybutyrate-co-3-hydroxyvalerate, PHBV) on heterotrophic and sulfur autotrophic cooperative denitrification (HAD) of aquaculture wastewater. Batch tests were carried out to analyze the effect of different PHBV/S volume ratios [...] Read more.
The aim of this study was to evaluate the effect of a solid slow-release carbon source (3-hydroxybutyrate-co-3-hydroxyvalerate, PHBV) on heterotrophic and sulfur autotrophic cooperative denitrification (HAD) of aquaculture wastewater. Batch tests were carried out to analyze the effect of different PHBV/S volume ratios in the range of 30–70% on the denitrification of synthetic aquaculture wastewater under a short hydraulic retention time (HRT). The performance of the HAD process showed that the NO3-N removal was increased with an increase in the PHBV/S volume ratio. When the PHBV/S ratio reached 70%, the average NO3-N concentration of effluent was 0.38 mg/L in the stable phase. The variation in pH and alkalinity showed that the average pH value and residual alkalinity were above 7.03 and 57.63 mg/L at the PHBV/S ratio of 50%. Based on the relationship between sulfate generation and nitrate removal under different ratios of PHBV/S, analysis of the proportion of autotrophic and heterotrophic denitrification (HD) showed that sulfur autotraophic denitrification (SAD) was enhanced at a PHBV/S ratio of 50%, and competition for nitrate substrates occurred between autotrophic and heterotrophic at a PHBV/S ratio of 70%. Full article
(This article belongs to the Section Environmental and Green Processes)
Show Figures

Figure 1

21 pages, 9041 KiB  
Article
All Deforestation Matters: Deforestation Alert System for the Caatinga Biome in South America’s Tropical Dry Forest
by Diego Pereira Costa, Carlos A. D. Lentini, André T. Cunha Lima, Soltan Galano Duverger, Rodrigo N. Vasconcelos, Stefanie M. Herrmann, Jefferson Ferreira-Ferreira, Mariana Oliveira, Leonardo da Silva Barbosa, Carlos Leandro Cordeiro, Nerivaldo Afonso Santos, Rafael Oliveira Franca Rocha, Deorgia T. M. Souza and Washington J. S. Franca Rocha
Sustainability 2024, 16(20), 9006; https://doi.org/10.3390/su16209006 - 17 Oct 2024
Cited by 2 | Viewed by 2997
Abstract
This study provides a comprehensive overview of Phase I of the deforestation dryland alert system. It focuses on its operation and outcomes from 2020 to 2022 in the Caatinga biome, a unique Brazilian dryland ecosystem. The primary objectives were to analyze deforestation dynamics, [...] Read more.
This study provides a comprehensive overview of Phase I of the deforestation dryland alert system. It focuses on its operation and outcomes from 2020 to 2022 in the Caatinga biome, a unique Brazilian dryland ecosystem. The primary objectives were to analyze deforestation dynamics, identify areas with highest deforestation rates, and determine regions that require prioritization for anti-deforestation efforts and conservation actions. The research methodology involved utilizing remote sensing data, including Landsat imagery, processed through the Google Earth Engine platform. The data were analyzed using spectral unmixing, adjusted Normalized Difference Fraction Index, and harmonic time series models to generate monthly deforestation alerts. The findings reveal a significant increase in deforestation alerts and deforested areas over the study period, with a 148% rise in alerts from 2020 to 2022. The Caatinga biome was identified as the second highest in detected deforestation alerts in Brazil in 2022, accounting for 18.4% of total alerts. Hexagonal assessments illustrate diverse vegetation cover and alert distribution, enabling targeted conservation efforts. The Bivariate Choropleth Map demonstrates the nuanced relationship between alert and vegetation cover, guiding prioritization for deforestation control and native vegetation restoration. The analysis also highlighted the spatial heterogeneity of deforestation, with most deforestation events occurring in small patches, averaging 10.9 ha. The study concludes that while the dryland alert system (SAD-Caatinga—Phase I) has effectively detected deforestation, ongoing challenges such as cloud cover, seasonality, and more frequent and precise monitoring persist. The implementation of DDAS plays a critical role in sustainable forestry by enabling the prompt detection of deforestation, which supports targeted interventions, helps contain the process, and provides decision makers with early insights to distinguish between legal and illegal practices. These capabilities inform decision-making processes and promote sustainable forest management in dryland ecosystems. Future improvements, including using higher-resolution imagery and artificial intelligence for validation, are essential to detect smaller deforestation alerts, reduce manual efforts, and support sustainable dryland management in the Caatinga biome. Full article
(This article belongs to the Special Issue Sustainable Forestry for a Sustainable Future)
Show Figures

Figure 1

20 pages, 4923 KiB  
Article
The Impact of Climate Variability on the Blooming of Fraxinus ornus ‘Globosa’ as a Component of Novi Sad’s (Serbia) Green Infrastructure
by Jelena Čukanović, Mirjana Ljubojević, Sara Djordjević, Tijana Narandžić, Djurdja Petrov and Mirjana Ocokoljić
Sustainability 2024, 16(19), 8404; https://doi.org/10.3390/su16198404 - 27 Sep 2024
Cited by 4 | Viewed by 1309
Abstract
Climate change increasingly impacts urban dendroflora, affecting plant physiology and phenological phases. This paper investigates the impact of changing climatic conditions on the blooming of Fraxinus ornus ‘Globosa’, a decorative form of ash that is a significant component of green infrastructure in Novi [...] Read more.
Climate change increasingly impacts urban dendroflora, affecting plant physiology and phenological phases. This paper investigates the impact of changing climatic conditions on the blooming of Fraxinus ornus ‘Globosa’, a decorative form of ash that is a significant component of green infrastructure in Novi Sad, Serbia. The research, conducted over 15 years on 42 individuals in a linear planting near a large river, analyzed temperature and precipitation effects on blooming times and inflorescence characteristics The results indicate changes in the timing of blooming, earlier than recorded in the literature, suggesting that temperature variations and changes in climatic conditions have significantly influenced the phenological phases of the selected clones of globe flowering ash. Additionally, the studied individuals showed exceptional adaptation to climate change and are not considered vulnerable. This study confirmed that this cultivar of flowering ash in urban environments is a key link in the green infrastructure of cities, functioning as green corridors along river flows as a nature-based solution. The studied cultivar is an important element of cultural heritage, contributing to the recreational potential of the linear composition of the promenade, especially during the flowering phenophase, when, in addition to its aesthetic values, it has psychological effects on users of the space, offering a calming influence due to its regular canopy and planting rhythm. Additionally, this cultivar provides important ecological functions, such as offering pollen for pollinators, thereby significantly contributing to the implementation of ecosystem services. Full article
Show Figures

Figure 1

18 pages, 317 KiB  
Article
AI-Driven Approach for Enhancing Sustainability in Urban Public Transportation
by Violeta Lukic Vujadinovic, Aleksandar Damnjanovic, Aleksandar Cakic, Dragan R. Petkovic, Marijana Prelevic, Vladan Pantovic, Mirjana Stojanovic, Dejan Vidojevic, Djordje Vranjes and Istvan Bodolo
Sustainability 2024, 16(17), 7763; https://doi.org/10.3390/su16177763 - 6 Sep 2024
Cited by 16 | Viewed by 8483
Abstract
The functioning of modern urban environments relies heavily on the public transport system. Given spatial, economic, and sustainability criteria, public transport in larger urban areas is unrivaled. The system’s role depends on the quality of service it offers. Achieving the desired service quality [...] Read more.
The functioning of modern urban environments relies heavily on the public transport system. Given spatial, economic, and sustainability criteria, public transport in larger urban areas is unrivaled. The system’s role depends on the quality of service it offers. Achieving the desired service quality requires a design that meets transport demands. This paper uses a data-driven approach to address headway deviations in public transport lines and explores ways to improve regularity during the design phase. Headway is a critical dynamic element for transport organization and passenger quality. Deviations between planned and actual headways represent disturbances. On lines with headways under 15 min, passengers typically do not consult schedules, making punctuality less crucial. Reduced headway regularity affects the average travel time, travel time uncertainty, and passenger comfort. Ideally, the public transport system operates with regular headways. However, disturbances can spread and affect subsequent departures, leading to vehicle bunching. While previous research focused on single primary disturbances, this study, with the help of AI (reinforcement learning), examines multiple primary disturbances in the cities of Belgrade, Novi Sad, and Niš. The goal is to model the cumulative impact of these disturbances on vehicle movement. By ranking parameter influences and using the automatic optimization of static line elements, this research aims to improve headway regularity and increase system resilience to disturbances. The results of this research could also be useful in developing adaptive public transport management systems that leverage AI and IoT technologies to continuously optimize headway regularity in response to real-time data, ultimately enhancing service quality and passenger satisfaction. Full article
12 pages, 240 KiB  
Article
The Content and Nature of Rumination in Chinese Young and Middle-Aged Patients with Acute Coronary Syndrome: A Qualitative Study
by Anan Li, Siying Ji, Yangfan Nie, Meixuan Chi, Naijuan Wang, Zhaoying Zhu, Shan Li and Yunying Hou
Healthcare 2024, 12(16), 1651; https://doi.org/10.3390/healthcare12161651 - 19 Aug 2024
Viewed by 1241
Abstract
Individuals have different rumination patterns after experiencing traumatic events in different cultural backgrounds and situations. This study aimed to explore the experience of Chinese young and middle-aged patients with acute coronary syndrome (ACS) to understand the content and nature of their rumination. Sixteen [...] Read more.
Individuals have different rumination patterns after experiencing traumatic events in different cultural backgrounds and situations. This study aimed to explore the experience of Chinese young and middle-aged patients with acute coronary syndrome (ACS) to understand the content and nature of their rumination. Sixteen participants were selected using the purposive sampling method in the First Affiliated Hospital of Soochow University from May 2023 to December 2023. Data were collected using semi-structured interviews and analyzed using Colaizzi’s seven-step phenomenological method. The participants went through two successive stages: non-adaptive rumination and adaptive rumination. During the initial admission phase, all the participants experienced varying degrees of non-adaptive rumination. Non-adaptive rumination included four sub-themes: worry or anxiety of daily activities and medical therapy (37.50%), fear of unpredictable outcomes and death (37.50%), sadness of maladjustment (25.00%), and remorse of carelessness (12.50%). During the period of stable condition and pre-discharge, the participants received health education and gradually all transitioned to adaptive rumination. Adaptive rumination included four sub-themes: tracing of disease processes (100%), enhancement of disease cognition (81.25%), improvement of health awareness (62.50%), and adjustment of lifestyle cognition (100%). In conclusion, although the Chinese young and middle-aged patients with ACS experienced negative emotions after a traumatic cardiac event, they gradually made positive changes, and optimism and information support played important roles in this transition. The results of this study provide a fundamental understanding of rumination experiences in Chinese young and middle-aged patients with ACS and provide new data for healthcare providers when designing intervention programs to enhance post-traumatic growth in these patients. Full article
18 pages, 6190 KiB  
Article
Physicochemical Properties of (La,Sr)CoO3 Thick Films on Fe-25Cr Steel under Exposure to SOFC Cathode Operating Conditions
by Janusz Prażuch, Michał Pyzalski, Daniel Fernández González and Tomasz Brylewski
Materials 2024, 17(15), 3791; https://doi.org/10.3390/ma17153791 - 1 Aug 2024
Cited by 1 | Viewed by 1081
Abstract
La0.6Sr0.4CoO3 (LSC) coatings with a thickness of 50–100 µm were deposited on Fe-25Cr ferritic stainless steel (DIN 50049) via screen printing. The required suspension had been prepared using fine LSC powders synthesised using EDTA gel processes. In its [...] Read more.
La0.6Sr0.4CoO3 (LSC) coatings with a thickness of 50–100 µm were deposited on Fe-25Cr ferritic stainless steel (DIN 50049) via screen printing. The required suspension had been prepared using fine LSC powders synthesised using EDTA gel processes. In its bulk form, the LSC consisted entirely of the rhombohedral phase with space group R-3c, and it exhibited high electrical conductivity (~144 S·cm−1). LSC-coated steel was oxidised in air at 1073 K, i.e., under conditions corresponding to SOFC cathode operation, for times of up to 144 h. The in situ electrical resistance of the steel/La0.6Sr0.4CoO3 layered system during oxidation was measured. The products formed on the samples after the oxidation reaction resulting from exposure to the corrosive medium were investigated using XRD, SEM-EDS, and TEM-SAD. The microstructural, nanostructural, phase, and chemical analysis of films was performed with a focus on the film/substrate interface. It was determined that the LSC coating interacts with the oxidised steel in the applied conditions, and a multi-layer interfacial zone is formed. Detailed TEM-SAD observations indicated the formation of a main layer consisting of SrCrO4, which was the reaction product of (La,Sr)CoO3, and the Cr2O3 scale formed on the metal surface. The formation of the SrCrO4 phase resulted in improved electrical conductivity of the investigated metal/ceramics layered composite material, as demonstrated by the low area-specific resistance values of 5 mΩ·cm2, thus making it potentially useful as a SOFC interconnect material operating at the tested temperature. In addition, the evaporation rate of chromium measured for the uncoated steel and the steel/La0.6Sr0.4CoO3 layered system likewise indicates that the coating is capable of acting as an effective barrier against the formation of volatile compounds of chromium. Full article
Show Figures

Figure 1

16 pages, 1746 KiB  
Article
By Carrot or by Stick: The Influence of Encouraging and Discouraging Facial Feedback on Implicit Rule Learning
by Yiling Liu, Muxin Ouyang, Wenjie Peng, Wenyang Zhang, Keming Lu, Yujun He, Xiangyan Zeng and Jie Yuan
Behav. Sci. 2024, 14(1), 36; https://doi.org/10.3390/bs14010036 - 5 Jan 2024
Viewed by 2357
Abstract
Implicit learning refers to the process of unconsciously learning complex knowledge through feedback. Previous studies investigated the influences of different types of feedback (e.g., social and non-social feedback) on implicit learning. This study focused on the social information presented in the learning situation [...] Read more.
Implicit learning refers to the process of unconsciously learning complex knowledge through feedback. Previous studies investigated the influences of different types of feedback (e.g., social and non-social feedback) on implicit learning. This study focused on the social information presented in the learning situation and tried to explore the effects of different social feedback on implicit rule learning. We assigned participants randomly into an encouraging facial feedback group (happy expression for correct answer, neutral but not negative expression for incorrect answer) and a discouraging facial feedback group (neutral but not happy expression for correct answer, negative expression for incorrect answer). The implicit learning task included four difficulty levels, and social feedback was presented in the learning phase but not the testing phase in two experiments. The only difference between the two experiments was that the sad face used as negative feedback in Experiment 1 was replaced with an angry face in Experiment 2 to enhance the ecological validity of the discouraging facial feedback group. These two experiments yielded consistent results: the performances in the encouraging facial feedback group were more accurate in both the learning and the testing phases at all difficulty levels. These findings indicated that the influence of encouraging social feedback for a better implicit learning achievement was stable and established a new groundwork for future research on incentive-based education, making it critical to investigate the impact of various forms of encouraging-based education on learning. Full article
(This article belongs to the Section Cognition)
Show Figures

Figure 1

15 pages, 5246 KiB  
Article
Heterogeneity in La Distribution in Highly La-Doped SrTiO3 Crystals
by Michał Marek Pilch, Christian Rodenbücher, Franciszek Krok and Kristof Szot
Crystals 2023, 13(11), 1552; https://doi.org/10.3390/cryst13111552 - 30 Oct 2023
Cited by 1 | Viewed by 1640
Abstract
Our paper is focused on the investigation of the dopant distribution in lanthanum-doped strontium titanate (LSTO) single crystals with a 5 wt.% doping level of La. Using X-ray diffraction analysis and pycnometric density measurement, we have found a discrepancy between the theoretical density [...] Read more.
Our paper is focused on the investigation of the dopant distribution in lanthanum-doped strontium titanate (LSTO) single crystals with a 5 wt.% doping level of La. Using X-ray diffraction analysis and pycnometric density measurement, we have found a discrepancy between the theoretical density and the experimentally determined value. The origin of this behavior could be either the creation of the voids in the matrix or the intergrowth of secondary phases with La surplus in the crystal. Transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), and selected area diffraction (SAD) microscopic investigation have confirmed the second hypothesis, namely, that in different regions of LSTO, the local concentration of La shows a substantial variation on the micro- and nanoscopic scale. In order to study the influence of the La dopants on the electronic structure and, therefore, on the electrical conductivity, we have used the local conductivity atomic force microscopy (LCAFM) method as a local electrical probe to map the in-plane electrical conductivity of the La-doped crystal’s surface. The LCAFM conductivity maps reveal heterogeneous conductivity (here in the form of the bands with higher conductivity than the surroundings), related to band-like inhomogeneities of the La distribution. Using LCAFM measurements with atomic resolution obtained between the conducting and nonconducting regions, we analyzed the spreading (spatial expansion) of doping on the undoped or low-doped part of the STO crystal. The found limitation of the doping effect of La on the dielectric part of the STO crystal to 4–5 lattice constants was in good correlation with ab initio studies from the literature. Full article
Show Figures

Figure 1

13 pages, 940 KiB  
Article
Emotional Distress in Portuguese Cancer Patients: The Use of the Emotion Thermometers (ET) Screening Tool
by Sónia Silva, Tiago Paredes, Ricardo João Teixeira, Tânia Brandão, Klára Dimitrovová, Diogo Marques, Joana Sousa, Monick Leal, Albina Dias, Carole Neves, Graciete Marques and Natália Amaral
Healthcare 2023, 11(19), 2689; https://doi.org/10.3390/healthcare11192689 - 6 Oct 2023
Cited by 1 | Viewed by 3443
Abstract
Cancer patients may experience significant distress. The “Emotion Thermometers” (ETs) are a short visual analogue scale used to screen patients for psychosocial risk. This study aimed to assess emotional distress in a large sample of cancer patients attending psychological services at an non-governmental [...] Read more.
Cancer patients may experience significant distress. The “Emotion Thermometers” (ETs) are a short visual analogue scale used to screen patients for psychosocial risk. This study aimed to assess emotional distress in a large sample of cancer patients attending psychological services at an non-governmental organization (NGO), and to explore factors that may contribute to it. The ETs were answered by 899 cancer patients. They were, on average, 59.9 years old, the majority were female, had breast cancer, were under treatment or were disease-free survivors, and reported high levels of emotional distress, above the cut-off (≥5). A Generalized Linear Model was used to measure the association between the level of distress, age, gender, disease phase and 33 items of the problem list. Four items—sadness, depression, sleep and breathing—were found to be significantly related to a higher level of distress. Additionally, women and patients who were in the palliative phase also had significantly higher levels of distress. The results confirm the need for early emotional screening in cancer patients, as well as attending to the characteristics of each patient. Additionally, they highlight the utility of the ETs for the clinical practice, allowing to optimize the referral to specialized psychosocial services. Full article
Show Figures

Figure 1

15 pages, 1868 KiB  
Article
Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study
by María Victoria González-López-Arza, José Vicente Triviño-Palomo, Jesús Montanero-Fernández, Elisa María Garrido-Ardila, Blanca González-Sánchez, María Jiménez-Palomares and Juan Rodríguez-Mansilla
Nutrients 2023, 15(15), 3469; https://doi.org/10.3390/nu15153469 - 5 Aug 2023
Cited by 4 | Viewed by 2564
Abstract
Background: Fibromyalgia (FM) is characterized by chronic widespread pain, as well as anxiety, sadness, and depression. These symptoms are present in most patients and have a negative impact on their daily, family, and social life. The role of neurotransmitters in the pathophysiology of [...] Read more.
Background: Fibromyalgia (FM) is characterized by chronic widespread pain, as well as anxiety, sadness, and depression. These symptoms are present in most patients and have a negative impact on their daily, family, and social life. The role of neurotransmitters in the pathophysiology of FM has been extensively discussed. The scientific evidence shows that levels of serotonin are decreased in patients with FM. Numerous studies support the beneficial effects that moderate wine consumption has on the body, with cardiovascular, endocrine, bone, and muscle improvements. Objective: The objective of this pilot study was to assess whether light consumption of red wine improves the main symptoms of FM. Methods: The study consisted of an experimental study with a control group with a total of 60 women diagnosed with FM following the American College of Rheumatology’s criteria. The experimental group ingested 15 g of alcohol per day, in the form of red wine, over a period of four weeks. The outcome measures were: the level of pain in tender points, sadness, anxiety, depression, and quality of life. The assessments tools were: tender point graphics, the visual analogue scale (for the assessment of pain and sadness), the Hamilton Anxiety Scale, the Hamilton Depression Rating Scale, and the Fibromyalgia Impact Questionnaire. The measurements were completed before and after the consumption of red wine. In addition, the differences between groups were evaluated in terms of drug consumption in the pre-intervention and follow-up phases. Results: Statistically significant improvements were obtained in the wine ingestion group for the variables of pain (p = 0.038), tender points (p < 0.001), and anxiety (p = 0.028). An improvement in the mean values was observed in favor of the experimental group for the variables of sadness, depression, and quality of life. The differences observed in the changes seen in the groups that were in favor of the wine ingestion group should not be attributed to the consumption of drugs but to the fact that the experimental group had a light intake of red wine. Conclusions: The results of this pilot study suggest a potential relationship between alcohol intake through the light consumption of red wine as part of the patients’ diet and the improvement of the main symptoms of fibromyalgia. Future studies are necessary to confirm these preliminary data; a bigger sample and a controlled diet should be considered, and the mechanisms through which improvements are achieved should be analyzed. Full article
Show Figures

Figure 1

24 pages, 5196 KiB  
Article
The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer’s Disease
by Wayne Chadwick, Stuart Maudsley, William Hull, Enes Havolli, Eugene Boshoff, Mark D. W. Hill, Pascal J. D. Goetghebeur, David C. Harrison, Sohaib Nizami, David C. Bedford, Gareth Coope, Katia Real, Christoph Thiemermann, Peter Maycox, Mark Carlton and Sarah L. Cole
Int. J. Mol. Sci. 2023, 24(8), 6953; https://doi.org/10.3390/ijms24086953 - 9 Apr 2023
Cited by 6 | Viewed by 2358
Abstract
Sporadic Alzheimer’s disease (sAD) represents a serious and growing worldwide economic and healthcare burden. Almost 95% of current AD patients are associated with sAD as opposed to patients presenting with well-characterized genetic mutations that lead to AD predisposition, i.e., familial AD (fAD). Presently, [...] Read more.
Sporadic Alzheimer’s disease (sAD) represents a serious and growing worldwide economic and healthcare burden. Almost 95% of current AD patients are associated with sAD as opposed to patients presenting with well-characterized genetic mutations that lead to AD predisposition, i.e., familial AD (fAD). Presently, the use of transgenic (Tg) animals overexpressing human versions of these causative fAD genes represents the dominant research model for AD therapeutic development. As significant differences in etiology exist between sAD and fAD, it is perhaps more appropriate to develop novel, more sAD-reminiscent experimental models that would expedite the discovery of effective therapies for the majority of AD patients. Here we present the oDGal mouse model, a novel model of sAD that displays a range of AD-like pathologies as well as multiple cognitive deficits reminiscent of AD symptomology. Hippocampal cognitive impairment and pathology were delayed with N-acetyl-cysteine (NaC) treatment, which strongly suggests that reactive oxygen species (ROS) are the drivers of downstream pathologies such as elevated amyloid beta and hyperphosphorylated tau. These features demonstrate a desired pathophenotype that distinguishes our model from current transgenic rodent AD models. A preclinical model that presents a phenotype of non-genetic AD-like pathologies and cognitive deficits would benefit the sAD field, particularly when translating therapeutics from the preclinical to the clinical phase. Full article
Show Figures

Figure 1

16 pages, 590 KiB  
Article
Effects of Mood on Psychophysiological Detection of Concealed Information and the Relation to Self-Assessed Lying Ability
by Eitan Elaad and Liza Zvi
Brain Sci. 2023, 13(2), 291; https://doi.org/10.3390/brainsci13020291 - 9 Feb 2023
Viewed by 2262
Abstract
The present study examined the effects of mood on physiological responses in the Concealed Information polygraph Test and the relation to self-assessed lying ability. One hundred and eight undergraduate students self-assessed their lie-telling ability, committed a mock theft, and were asked to conceal [...] Read more.
The present study examined the effects of mood on physiological responses in the Concealed Information polygraph Test and the relation to self-assessed lying ability. One hundred and eight undergraduate students self-assessed their lie-telling ability, committed a mock theft, and were asked to conceal information related to the crime. Participants were then divided into three equal groups: two groups were asked to provide a detailed written account of either a happy or sad event in order to induce a happy or sad mood, while the third group served as a neutral group. Participants then underwent a polygraph test and were asked to try to avoid detection. An induced happy or sad mood tended to lower relative skin conductance responses to critical (crime related) items and enhance relative cardiovascular responses. Relative respiration responses to critical items obtained for the sad mood condition were more robust than the ones obtained for the happy mood condition. Under induced sad and happy moods, those who self-rated their lie-telling ability as high showed enhanced cardiovascular responsivity to critical items. These results were limited to the initial phase of the test. We discussed possible motivational explanations and implications for the Concealed Information polygraph test. Full article
(This article belongs to the Special Issue Cognitive Approaches to Deception Research)
Show Figures

Graphical abstract

Back to TopTop