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Search Results (351)

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27 pages, 1825 KB  
Review
A Comparative Review of Quantum Neural Networks and Classical Machine Learning for Cardiovascular Disease Risk Prediction
by Nouf Ali AL Ajmi and Muhammad Shoaib
Computers 2026, 15(2), 102; https://doi.org/10.3390/computers15020102 - 2 Feb 2026
Abstract
Cardiac risk prediction is critical for the early detection and prevention of cardiovascular diseases, a leading global cause of mortality. In response to the growing volume and complexity of healthcare data, there has been increasing reliance on computational approaches to enhance clinical decision-making [...] Read more.
Cardiac risk prediction is critical for the early detection and prevention of cardiovascular diseases, a leading global cause of mortality. In response to the growing volume and complexity of healthcare data, there has been increasing reliance on computational approaches to enhance clinical decision-making and improve early detection of cardiac risks. Although classical machine learning techniques have demonstrated strong performance in cardiovascular disease prediction, their efficiency and scalability are increasingly challenged by high-dimensional and large-scale medical datasets. Emerging advances in quantum computing have introduced quantum machine learning (QML) as a promising alternative, offering novel computational paradigms with the potential to outperform classical methods in terms of speed and problem-solving capability. This review analyzed twelve studies, evaluating data types, quantum architecture, performance metrics, and comparative efficacy against classical machine learning models. Our findings indicate that QNNs show promise for enhanced predictive accuracy and computational efficiency. However, significant challenges in scalability, noise resilience, and clinical integration persist. The translation of quantum advantage into clinical practice necessitates further validation on large-scale with diverse datasets. Full article
(This article belongs to the Special Issue Machine and Deep Learning in the Health Domain (3rd Edition))
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25 pages, 1448 KB  
Article
SDEQ-Net: A Deepfake Video Anomaly Detection Method Integrating Stochastic Differential Equations and Hermitian-Symmetric Quantum Representations
by Ruixing Zhang, Bin Li and Degang Xu
Symmetry 2026, 18(2), 259; https://doi.org/10.3390/sym18020259 - 30 Jan 2026
Viewed by 81
Abstract
With the rapid advancement of deepfake generation technologies, forged videos have become increasingly realistic in visual quality and temporal consistency, posing serious threats to multimedia security. Existing detection methods often struggle to effectively model temporal dynamics and capture subtle inter-frame anomalies. To address [...] Read more.
With the rapid advancement of deepfake generation technologies, forged videos have become increasingly realistic in visual quality and temporal consistency, posing serious threats to multimedia security. Existing detection methods often struggle to effectively model temporal dynamics and capture subtle inter-frame anomalies. To address these challenges, we propose a Stochastic Differential Equation and Quantum Uncertainty Network (SDEQ-Net), a novel deepfake video anomaly detection framework that integrates continuous time stochastic modeling with quantum uncertainty mechanisms. First, a Continuous Time Neural Stochastic Differential Filtering Module (CNSDFM) is introduced to characterize the continuous evolution of latent inter-frame states using neural stochastic differential equations, enabling robust temporal filtering and uncertainty estimation. Second, a Quantum Uncertainty Aware Fusion Module (QUAFM) incorporates Hermitian-symmetric density matrix representations and von Neumann entropy to enhance feature fusion under uncertainty, leveraging the mathematical symmetry properties of quantum state representations for principled uncertainty quantification. Third, a Fractional Order Temporal Anomaly Detection Module (FOTADM) is proposed to generate fine grained temporal anomaly scores based on fractional order residuals, which are used as dynamic weights to guide attention toward anomalous frames. Extensive experiments on three benchmark datasets, including FaceForensics++, Celeb-DF, and DFDC, demonstrate the effectiveness of the proposed method. SDEQ-Net achieves AUC scores of 99.81% on FF++ (c23) and 97.91% on FF++ (c40). In cross dataset evaluations, it obtains 89.55% AUC on Celeb-DF and 86.21% AUC on DFDC, consistently outperforming existing state-of-the-art methods in both detection accuracy and generalization capability. Full article
(This article belongs to the Section Computer)
20 pages, 1275 KB  
Article
QEKI: A Quantum–Classical Framework for Efficient Bayesian Inversion of PDEs
by Jiawei Yong and Sihai Tang
Entropy 2026, 28(2), 156; https://doi.org/10.3390/e28020156 - 30 Jan 2026
Viewed by 72
Abstract
Solving Bayesian inverse problems efficiently stands as a major bottleneck in scientific computing. Although Bayesian Physics-Informed Neural Networks (B-PINNs) have introduced a robust way to quantify uncertainty, the high-dimensional parameter spaces inherent in deep learning often lead to prohibitive sampling costs. Addressing this, [...] Read more.
Solving Bayesian inverse problems efficiently stands as a major bottleneck in scientific computing. Although Bayesian Physics-Informed Neural Networks (B-PINNs) have introduced a robust way to quantify uncertainty, the high-dimensional parameter spaces inherent in deep learning often lead to prohibitive sampling costs. Addressing this, our work introduces Quantum-Encodable Bayesian PINNs trained via Classical Ensemble Kalman Inversion (QEKI), a framework that pairs Quantum Neural Networks (QNNs) with Ensemble Kalman Inversion (EKI). The core advantage lies in the QNN’s ability to act as a compact surrogate for PDE solutions, capturing complex physics with significantly fewer parameters than classical networks. By adopting the gradient-free EKI for training, we mitigate the barren plateau issue that plagues quantum optimization. Through several benchmarks on 1D and 2D nonlinear PDEs, we show that QEKI yields precise inversions and substantial parameter compression, even in the presence of noise. While large-scale applications are constrained by current quantum hardware, this research outlines a viable hybrid framework for including quantum features within Bayesian uncertainty quantification. Full article
(This article belongs to the Special Issue Quantum Computation, Quantum AI, and Quantum Information)
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18 pages, 4873 KB  
Article
Quantum Neural Network Realization of XOR on a Desktop Quantum Computer
by Tee Hui Teo, Qianrui Lin and Yiyang Fu
Sensors 2026, 26(3), 854; https://doi.org/10.3390/s26030854 - 28 Jan 2026
Viewed by 289
Abstract
Quantum neural networks leverage quantum computing to address machine learning problems beyond the capabilities of classical computing. In this study, we demonstrate a quantum neural network that learns the nonlinear exclusive OR function on a desktop quantum computer. The exclusive OR task is [...] Read more.
Quantum neural networks leverage quantum computing to address machine learning problems beyond the capabilities of classical computing. In this study, we demonstrate a quantum neural network that learns the nonlinear exclusive OR function on a desktop quantum computer. The exclusive OR task is a nonlinear benchmark that cannot be solved by a single-layer perceptron, making it an excellent test for quantum machine learning. We trained a variational quantum circuit model in a simulation using the PennyLane framework to learn the two-bit exclusive OR mapping. After obtaining the circuit parameters in the simulation, the trained quantum neural network was deployed on a two-qubit Nuclear Magnetic Resonance-based desktop quantum computer operating at room temperature to evaluate the actual hardware performance. The experimental quantum state fidelity reached approximately 98.85%(Ry) and 99.35%(Rx), and the overall average purity was 95.16%(Ry) and 97.43%(Rx), indicating excellent agreement between the expected and measured results. These positive outcomes underscore the feasibility of quantum machine learning on small-scale quantum hardware, marking a minimal yet physically meaningful benchmark. Full article
(This article belongs to the Special Issue AI for Sensor Devices, Circuits and System Design)
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13 pages, 3858 KB  
Article
Time Series Prediction of Open Quantum System Dynamics by Transformer Neural Networks
by Zhao-Wei Wang, Lian-Ao Wu and Zhao-Ming Wang
Entropy 2026, 28(2), 133; https://doi.org/10.3390/e28020133 - 23 Jan 2026
Viewed by 193
Abstract
The dynamics of open quantum systems play a crucial role in quantum information science. However, obtaining numerically exact solutions for the Lindblad master equation is often computationally expensive. Recently, machine learning techniques have gained considerable attention for simulating open quantum system dynamics. In [...] Read more.
The dynamics of open quantum systems play a crucial role in quantum information science. However, obtaining numerically exact solutions for the Lindblad master equation is often computationally expensive. Recently, machine learning techniques have gained considerable attention for simulating open quantum system dynamics. In this paper, we propose a deep learning model based on time series prediction (TSP) to forecast the dynamical evolution of open quantum systems. We employ the positive operator-valued measure (POVM) approach to convert the density matrix of the system into a probability distribution and construct a TSP model based on Transformer neural networks. This model effectively captures the historical evolution patterns of the system and accurately predicts its future behavior. Our results show that the model achieves high-fidelity predictions of the system’s evolution trajectory in both short- and long-term scenarios, and exhibits robust generalization under varying initial states and coupling strengths. Moreover, we successfully predicted the steady-state behavior of the system, further proving the practicality and scalability of the method. Full article
(This article belongs to the Special Issue Non-Markovian Open Quantum Systems)
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32 pages, 18470 KB  
Article
Enhancing Neuromorphic Robustness via Recurrence Resonance: The Role of Shared Weak Attractors in Quantum Logic Networks
by Yu Huang and Yukio-Pegio Gunji
Biomimetics 2026, 11(1), 81; https://doi.org/10.3390/biomimetics11010081 - 19 Jan 2026
Viewed by 319
Abstract
Recurrence resonance, a phenomenon that enhances system computational capability by exploiting noise to amplify hidden attractors, holds significant potential for applications such as edge computing and neuromorphic computing. Although previous studies have extensively explored its characteristics, the underlying mechanism regarding its generation remains [...] Read more.
Recurrence resonance, a phenomenon that enhances system computational capability by exploiting noise to amplify hidden attractors, holds significant potential for applications such as edge computing and neuromorphic computing. Although previous studies have extensively explored its characteristics, the underlying mechanism regarding its generation remains unclear. Here, we employed a Stochastic Recurrent Neural Network to simulate neural networks under various coupling conditions. By introducing appropriate inhibitory connections and examining the state transition matrices, we analyzed the characteristics and correlations of attractor landscapes in both global and local systems to elucidate the generative mechanism behind the “Edge of Chaos” dynamics observed under the quantum logic connectivity structure during recurrence resonance. The results show that the strategic introduction of inhibitory connections enriches the system’s attractor landscape without compromising the intensity of recurrence resonance. Furthermore, we find that when neurons are coupled via quantum logic and noise intensity meets specific conditions, the strong attractors of the global system decompose into those of distinct local subsystems, accompanied by the sharing of structurally similar weak attractors. These findings suggest that under quantum logic connectivity, the interaction between the strong attractors of different subsystems is mediated by a background of shared weak attractors, thereby enhancing both the system’s robustness against noise and the diversity of its state evolution. Full article
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24 pages, 3292 KB  
Article
Comparing Emerging and Hybrid Quantum–Kolmogorov Architectures for Image Classification
by Lelio Campanile, Mariarosaria Castaldo, Stefano Marrone and Fabio Napoli
Computers 2026, 15(1), 65; https://doi.org/10.3390/computers15010065 - 16 Jan 2026
Viewed by 348
Abstract
The rapid evolution of Artificial Intelligence has enabled significant progress in image classification, with emerging approaches extending traditional deep learning paradigms. This article presents an extended version of a paper originally introduced at ICCSA 2025, providing a broader comparative analysis of classical, spline-based, [...] Read more.
The rapid evolution of Artificial Intelligence has enabled significant progress in image classification, with emerging approaches extending traditional deep learning paradigms. This article presents an extended version of a paper originally introduced at ICCSA 2025, providing a broader comparative analysis of classical, spline-based, and quantum machine learning architectures. The study evaluates Convolutional Neural Networks (CNNs), Kolmogorov–Arnold Networks (KANs), Convolutional KANs (CKANs), and Quantum Convolutional Neural Networks (QCNNs) on the Labeled Faces in the Wild dataset. In addition to these baselines, two novel architectures are introduced: a fully quantum Kolmogorov–Arnold model (F-QKAN) and a hybrid KAN–Quantum network (H-QKAN) that combines spline-based feature extraction with variational quantum classification. Rather than targeting state-of-the-art performance, the evaluation focuses on analyzing the behaviour of these architectures in terms of accuracy, computational efficiency, and interpretability under a unified experimental protocol. Results show that the fully quantum F-QKAN achieves a test accuracy above 80%. The hybrid H-QKAN obtains the best overall performance, exceeding 92% accuracy with rapid convergence and stable training dynamics. Classical CNNs models remain state-of-the-art in terms of predictive performance, whereas CKANs offer a favorable balance between accuracy and efficiency. QCNNs show potential in ideal noise-free settings but are significantly affected by realistic noise conditions, motivating further investigation into hybrid quantum–classical designs. Full article
(This article belongs to the Special Issue Computational Science and Its Applications 2025 (ICCSA 2025))
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22 pages, 1144 KB  
Article
Exploring Quantum-Inspired Encoding Strategies in Neuromorphic Systems for Affective State Recognition
by Fang Wang, Xiaoqiang Liang and Xingqian Du
Sensors 2026, 26(2), 568; https://doi.org/10.3390/s26020568 - 14 Jan 2026
Viewed by 357
Abstract
In this paper, we explore the spiking encoding methodology within spiking neural networks for affective state recognition, deriving inspiration from the principles of quantum entanglement. A pioneering encoding strategy is proposed based on the strategic utilization of the quantum mechanical phenomenon of entanglement. [...] Read more.
In this paper, we explore the spiking encoding methodology within spiking neural networks for affective state recognition, deriving inspiration from the principles of quantum entanglement. A pioneering encoding strategy is proposed based on the strategic utilization of the quantum mechanical phenomenon of entanglement. By integrating quantum mechanisms into the spike-encoding pipeline, we aim to match the accuracy of existing encoders on emotion-classification tasks while retaining the inherently low-power advantage of spiking neural networks. Notably, leveraging the superposition of quantum bits and their potential quantum entanglement of adjacent values in feature space during encoding calculations, this quantum-inspired encoding paradigm holds substantial promise for augmenting information processing capabilities in brain-like neural networks. Through quantum observation, we derive spike trains characterized by quantum states, thereby establishing a foundation for experimental validation and subsequent investigative pursuits. We conducted experiments on emotion recognition and validated the effectiveness of our method. Full article
(This article belongs to the Special Issue Emotion Recognition Based on Sensors (3rd Edition))
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14 pages, 1819 KB  
Article
A Hybrid Model with Quantum Feature Map Based on CNN and Vision Transformer for Clinical Support in Diagnosis of Acute Appendicitis
by Zeki Ogut, Mucahit Karaduman, Pinar Gundogan Bozdag, Mehmet Karakose and Muhammed Yildirim
Biomedicines 2026, 14(1), 183; https://doi.org/10.3390/biomedicines14010183 - 14 Jan 2026
Viewed by 281
Abstract
Background/Objectives: Rapid and accurate diagnosis of acute appendicitis is crucial for patient health and management, and the diagnostic process can be prolonged due to varying clinical symptoms and limitations of diagnostic tools. This study aims to shorten the timeframe for these vital [...] Read more.
Background/Objectives: Rapid and accurate diagnosis of acute appendicitis is crucial for patient health and management, and the diagnostic process can be prolonged due to varying clinical symptoms and limitations of diagnostic tools. This study aims to shorten the timeframe for these vital processes and increase accuracy by developing a quantum-inspired hybrid model to identify appendicitis types. Methods: The developed model initially selects the two most performing architectures using four convolutional neural networks (CNNs) and two Transformers (ViTs). Feature extraction is then performed from these architectures. Phase-based trigonometric embedding, low-order interactions, and norm-preserving principles are used to generate a Quantum Feature Map (QFM) from these extracted features. The generated feature map is then passed to the Multiple Head Attention (MHA) layer after undergoing Hadamard fusion. At the end of this stage, classification is performed using a multilayer perceptron (MLP) with a ReLU activation function, which allows for the identification of acute appendicitis types. The developed quantum-inspired hybrid model is also compared with six different CNN and ViT architectures recognized in the literature. Results: The proposed quantum-inspired hybrid model outperformed the other models used in the study for acute appendicitis detection. The accuracy achieved in the proposed model was 97.96%. Conclusions: While the performance metrics obtained from the quantum-inspired model will form the basis of deep learning architectures for quantum technologies in the future, it is thought that if 6G technology is used in medical remote interventions, it will form the basis for real-time medical interventions by taking advantage of quantum speed. Full article
(This article belongs to the Section Biomedical Engineering and Materials)
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23 pages, 1961 KB  
Article
Quantum-Resilient Federated Learning for Multi-Layer Cyber Anomaly Detection in UAV Systems
by Canan Batur Şahin
Sensors 2026, 26(2), 509; https://doi.org/10.3390/s26020509 - 12 Jan 2026
Viewed by 331
Abstract
Unmanned Aerial Vehicles (UAVs) are increasingly used in civilian and military applications, making their communication and control systems targets for cyber attacks. The emerging threat of quantum computing amplifies these risks. Quantum computers could break the classical cryptographic schemes used in current UAV [...] Read more.
Unmanned Aerial Vehicles (UAVs) are increasingly used in civilian and military applications, making their communication and control systems targets for cyber attacks. The emerging threat of quantum computing amplifies these risks. Quantum computers could break the classical cryptographic schemes used in current UAV networks. This situation underscores the need for quantum-resilient, privacy-preserving security frameworks. This paper proposes a quantum-resilient federated learning framework for multi-layer cyber anomaly detection in UAV systems. The framework combines a hybrid deep learning architecture. A Variational Autoencoder (VAE) performs unsupervised anomaly detection. A neural network classifier enables multi-class attack categorization. To protect sensitive UAV data, model training is conducted using federated learning with differential privacy. Robustness against malicious participants is ensured through Byzantine-robust aggregation. Additionally, CRYSTALS-Dilithium post-quantum digital signatures are employed to authenticate model updates and provide long-term cryptographic security. Researchers evaluated the proposed framework on a real UAV attack dataset containing GPS spoofing, GPS jamming, denial-of-service, and simulated attack scenarios. Experimental results show the system achieves 98.67% detection accuracy with only 6.8% computational overhead compared to classical cryptographic approaches, while maintaining high robustness under Byzantine attacks. The main contributions of this study are: (1) a hybrid VAE–classifier architecture enabling both zero-day anomaly detection and precise attack classification, (2) the integration of Byzantine-robust and privacy-preserving federated learning for UAV security, and (3) a practical post-quantum security design validated on real UAV communication data. Full article
(This article belongs to the Section Vehicular Sensing)
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31 pages, 3167 KB  
Article
A Blockchain-Based Framework for Secure Healthcare Data Transfer and Disease Diagnosis Using FHM C-Means and LCK-CMS Neural Network
by Obada Al-Khatib, Ghalia Nassreddine, Amal El Arid, Abeer Elkhouly and Mohamad Nassereddine
Sci 2026, 8(1), 13; https://doi.org/10.3390/sci8010013 - 9 Jan 2026
Viewed by 399
Abstract
IoT-based blockchain technology has improved the healthcare system to ensure the privacy and security of healthcare data. A Blockchain Bridge (BB) is a tool that enables multiple blockchain networks to communicate with each other. The existing approach combining the classical and quantum blockchain [...] Read more.
IoT-based blockchain technology has improved the healthcare system to ensure the privacy and security of healthcare data. A Blockchain Bridge (BB) is a tool that enables multiple blockchain networks to communicate with each other. The existing approach combining the classical and quantum blockchain models failed to secure the data transmission during cross-chain communication. Thus, this study proposes a new BB verification for secure healthcare data transfer. Additionally, a brain tumor analysis framework is developed based on segmentation and neural networks. After the patient’s registration on the blockchain network, Brain Magnetic Resonance Imaging (MRI) data is encrypted using Hash-Keyed Quantum Cryptography and verified using a Peer-to-Peer Exchange model. The Brain MRI is preprocessed for brain tumor detection using the Fuzzy HaMan C-Means (FHMCM) segmentation technique. The features are extracted from the segmented image and classified using the LeCun Kaiming-based Convolutional ModSwish Neural Network (LCK-CMSNN) classifier. Subsequently, the brain tumor diagnosis report is securely transferred to the patient via a smart contract. The proposed model verified BB with a Verification Time (VT) of 12,541 ms, secured the input with a Security level (SL) of 98.23%, and classified the brain tumor with 99.15% accuracy, thus showing better performance than the existing models. Full article
(This article belongs to the Section Computer Sciences, Mathematics and AI)
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13 pages, 912 KB  
Article
Artificial Intelligence for Studying Interactions of Solitons and Peakons
by Angela Slavova and Ventsislav Ignatov
Mathematics 2026, 14(1), 180; https://doi.org/10.3390/math14010180 - 3 Jan 2026
Viewed by 315
Abstract
In this paper, Artificial Intelligence (AI) is developed for studying the Boussinesq Paradigm equation and so called b-equation based on Physics-Informed Cellular Neural Networks (PICNNs). The models studied here come from fluid dynamics. Machine learning through Physics-Informed Neural Networks (PINNs) is a powerful [...] Read more.
In this paper, Artificial Intelligence (AI) is developed for studying the Boussinesq Paradigm equation and so called b-equation based on Physics-Informed Cellular Neural Networks (PICNNs). The models studied here come from fluid dynamics. Machine learning through Physics-Informed Neural Networks (PINNs) is a powerful tool for solving complex problems arising in physical laws. By optimization and automatic differentiation, the solutions of the model under consideration can be approximated precisely and can be obtained in real time. In this paper, we shall apply a new algorithm based on Physics-Informed Cellular Neural Networks (PICNNs) for obtaining the interactions between solitons and peakons. The algorithm has many advantages, but the main ones are that it provides the fastest programming and solutions in real time. It is known that Cellular Neural Networks (CNNs) have the ability to approximate, in a very accurate way, nonlinear partial differential equations (PDEs) and to present their solutions in real time. By incorporating the physical laws into the learning process through PICNN we can solve various problems from fluid dynamics, material science, and quantum mechanics. Full article
(This article belongs to the Special Issue Applications of Differential Equations in Sciences)
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37 pages, 2575 KB  
Review
A Review of High-Throughput Optical Sensors for Food Detection Based on Machine Learning
by Yuzhen Wang, Yuchen Yang and Huilin Liu
Foods 2026, 15(1), 133; https://doi.org/10.3390/foods15010133 - 2 Jan 2026
Viewed by 545
Abstract
As the global food industry expands and consumers demand higher food safety and quality standards, high-throughput detection technology utilizing digital intelligent optical sensors has emerged as a research hotspot in food testing due to its advantages of speed, precision, and non-destructive operation. Integrating [...] Read more.
As the global food industry expands and consumers demand higher food safety and quality standards, high-throughput detection technology utilizing digital intelligent optical sensors has emerged as a research hotspot in food testing due to its advantages of speed, precision, and non-destructive operation. Integrating cutting-edge achievements in optics, electronics, and computer science with machine learning algorithms, this technology efficiently processes massive datasets. This paper systematically summarizes the construction principles of intelligent optical sensors and their applications in food inspection. Sensors convert light signals into electrical signals using nanomaterials such as quantum dots, metal nanoparticles, and upconversion nanoparticles, and then employ machine learning algorithms including support vector machines, random forests, and convolutional neural networks for data analysis and model optimization. This enables efficient detection of target substances like pesticide residues, heavy metals, microorganisms, and food freshness. Furthermore, the integration of multiple detection mechanisms—including spectral analysis, fluorescence imaging, and hyperspectral imaging—has significantly broadened the sensors’ application scenarios. Looking ahead, optical sensors will evolve toward multifunctional integration, miniaturization, and intelligent operation. By leveraging cloud computing and IoT technologies, they will deliver innovative solutions for comprehensive monitoring of food quality and safety across the entire supply chain. Full article
(This article belongs to the Special Issue Advances in AI for the Quality Assessment of Agri-Food Products)
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14 pages, 319 KB  
Article
AI-Enhanced Perceptual Hashing with Blockchain for Secure and Transparent Digital Copyright Management
by Zhaoxiong Meng, Rukui Zhang, Bin Cao, Meng Zhang, Yajun Li, Huhu Xue and Meimei Yang
Cryptography 2026, 10(1), 2; https://doi.org/10.3390/cryptography10010002 - 29 Dec 2025
Viewed by 435
Abstract
This study presents a novel framework for digital copyright management that integrates AI-enhanced perceptual hashing, blockchain technology, and digital watermarking to address critical challenges in content protection and verification. Traditional watermarking approaches typically employ content-independent metadata and rely on centralized authorities, introducing risks [...] Read more.
This study presents a novel framework for digital copyright management that integrates AI-enhanced perceptual hashing, blockchain technology, and digital watermarking to address critical challenges in content protection and verification. Traditional watermarking approaches typically employ content-independent metadata and rely on centralized authorities, introducing risks of tampering and operational inefficiencies. The proposed system utilizes a pre-trained convolutional neural network (CNN) to generate a robust, content-based perceptual hash value, which serves as an unforgeable watermark intrinsically linked to the image content. This hash is embedded as a QR code in the frequency domain and registered on a blockchain, ensuring tamper-proof timestamping and comprehensive traceability. The blockchain infrastructure further enables verification of multiple watermark sequences, thereby clarifying authorship attribution and modification history. Experimental results demonstrate high robustness against common image modifications, strong discriminative capabilities, and effective watermark recovery, supported by decentralized storage via the InterPlanetary File System (IPFS). The framework provides a transparent, secure, and efficient solution for digital rights management, with potential future enhancements including post-quantum cryptography integration. Full article
(This article belongs to the Special Issue Interdisciplinary Cryptography)
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22 pages, 887 KB  
Review
Advancing Identification of Transformation Products and Predicting Their Environmental Fate: The Current State of Machine Learning and Artificial Intelligence in Antibiotic Photolysis
by Sultan K. Alharbi
Appl. Sci. 2026, 16(1), 267; https://doi.org/10.3390/app16010267 - 26 Dec 2025
Viewed by 602
Abstract
The environmental persistence of antibiotic residues in aquatic systems represents a critical global challenge, with photolysis serving as a primary abiotic degradation pathway. Traditional approaches to studying antibiotic photodegradation and transformation product (TP) identification face significant limitations, including complex reaction mechanisms, multiple concurrent [...] Read more.
The environmental persistence of antibiotic residues in aquatic systems represents a critical global challenge, with photolysis serving as a primary abiotic degradation pathway. Traditional approaches to studying antibiotic photodegradation and transformation product (TP) identification face significant limitations, including complex reaction mechanisms, multiple concurrent pathways, and analytical challenges in characterizing unknown metabolites. The integration of artificial intelligence (AI) and machine learning (ML) technologies has begun to transform this field, offering new capabilities for predicting photodegradation kinetics, elucidating transformation pathways, and identifying novel metabolites. This comprehensive review examines current applications of AI/ML in antibiotic photolysis research, analyzing developments from 2020 to 2025. Key advances include quantitative structure–activity relationship (QSAR) models for photodegradation prediction, deep learning approaches for automated mass spectrometry interpretation, and hybrid computational–experimental frameworks. Machine learning algorithms, particularly Random Forests, support vector machines, and Neural Networks, have demonstrated capabilities in handling multi-dimensional environmental datasets across diverse antibiotic classes, including fluoroquinolones, β-lactams, tetracyclines, and sulfonamides. Despite progress in this field, challenges remain in model interpretability, standardization of datasets, validation protocols, and integration with regulatory frameworks. Future directions include machine-learning-enhanced quantum dynamics for improving mechanistic understanding, real-time AI-guided experimental design, and predictive tools for environmental risk assessment. Full article
(This article belongs to the Section Environmental Sciences)
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