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  • Article
  • Open Access
37 Citations
4,337 Views
11 Pages

Deep Learning-Based Differentiation between Mucinous Cystic Neoplasm and Serous Cystic Neoplasm in the Pancreas Using Endoscopic Ultrasonography

  • Leang Sim Nguon,
  • Kangwon Seo,
  • Jung-Hyun Lim,
  • Tae-Jun Song,
  • Sung-Hyun Cho,
  • Jin-Seok Park and
  • Suhyun Park

Mucinous cystic neoplasms (MCN) and serous cystic neoplasms (SCN) account for a large portion of solitary pancreatic cystic neoplasms (PCN). In this study we implemented a convolutional neural network (CNN) model using ResNet50 to differentiate betwe...

  • Case Report
  • Open Access
2 Citations
875 Views
3 Pages

1 February 2014

Oncocytoma is an uncommon neoplasm with a characteristic histologic feature of abundant eosinophilic granular cytoplasm. It almost always occurs in kidney, thyroid, or salivary gland. Pulmonary oncocytoma is a rare pulmonary neoplasm, with fewer than...

  • Case Report
  • Open Access
2 Citations
2,481 Views
8 Pages

Extramedullary T-lymphoblastic Crisis in a Myelodysplastic/Myeloproliferative Neoplasm with a t(12;22)/MN1::ETV6 Translocation

  • Ana Carolina Freitas,
  • Tiago Maia,
  • Joana Desterro,
  • Francesca Pierdomenico,
  • Albertina Nunes,
  • Isabelina Ferreira,
  • José Cabeçadas and
  • Maria Gomes da Silva

14 March 2023

Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) are not a single disease, but rather a heterogenous group of entities which are increasingly subclassified according to recurrent genetic abnormalities. Chromosomal translocations involving menin...

  • Interesting Images
  • Open Access
1 Citations
1,452 Views
6 Pages

14 September 2024

We report a rare case of low-grade appendiceal mucinous neoplasm (LAMN) causing ileocolic intussusception. The case underscores the importance of considering ileocolic intussusception in differential diagnoses for nonspecific gastrointestinal symptom...

  • Systematic Review
  • Open Access
324 Views
19 Pages

Secondary Neoplasm in Survivors of Childhood Hematological Malignancies—Systematic Review

  • Ioana-Alexandra Horneț,
  • Andreea Bianca Stoica,
  • Dora Mihaela Cîmpian and
  • Lucian Puşcaşiu

31 January 2026

Background: Childhood cancers account for approximately 1–2% of all malignancies worldwide, with hematologic cancers representing about 35–40% of pediatric cases. Improved survival has brought increased recognition of both acute and long-...

  • Review
  • Open Access
2 Citations
3,268 Views
17 Pages

Uterine tumor resembling ovarian sex-cord tumor (UTROSCT) is a rare form of uterine mesenchymal neoplasm. Although UTROSCT generally exhibits benign behavior with a favorable prognosis, this neoplasm is nevertheless classified as being of uncertain m...

  • Article
  • Open Access
1,800 Views
14 Pages

Classification and Prognostic Stratification Based on Genomic Features in Myelodysplastic and Myeloproliferative Neoplasm- and Their Overlapping Conditions

  • Jong-Mi Lee,
  • Ginkyeng Lee,
  • Taeksang Kim,
  • Ari Ahn,
  • Jin Jung,
  • Yoo-Jin Kim,
  • Silvia Park,
  • Daehun Kwag,
  • Sung-Eun Lee and
  • Myungshin Kim
  • + 8 authors

9 December 2024

Background/Objectives: Myeloid neoplasms encompass a diverse group of disorders. In this study, we aimed to analyze the clinical and genomic data of patients with myeloproliferative neoplasm (MPN), myelodysplastic neoplasm (MDS), and their overlappin...

  • Article
  • Open Access
2,166 Views
14 Pages

21 August 2023

The purpose of this study is to investigate the expression of the epithelial membrane proteins (EMP) 1, 2, and 3 in adrenal gland neoplasm and to explore the broader implications of this. Tissue microarrays were constructed for 132 cases of adrenal c...

  • Case Report
  • Open Access
391 Views
9 Pages

Targeted Therapy for a Rare PDGFRB-Rearranged Myeloproliferative Neoplasm: A Case Report

  • Cosimo Barbato,
  • Vito A. Lasorsa,
  • Francesco Grimaldi,
  • Santa Errichiello,
  • Ida Pisano,
  • Maurizio Capuozzo,
  • Mariangela Capone,
  • Viviana Izzo,
  • Fabrizio Quarantelli and
  • Barbara Izzo
  • + 10 authors

Myeloproliferative neoplasms (MPNs) are a heterogeneous group of diseases originating from hematopoietic stem cell transformation, characterized by the clonal proliferation of hematopoietic progenitors. A specific subset includes myeloid/lymphoid neo...

  • Review
  • Open Access
81 Citations
11,596 Views
16 Pages

Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects

  • Maria Rosaria Sapienza,
  • Alessandro Pileri,
  • Enrico Derenzini,
  • Federica Melle,
  • Giovanna Motta,
  • Stefano Fiori,
  • Angelica Calleri,
  • Nicola Pimpinelli,
  • Valentina Tabanelli and
  • Stefano Pileri

28 April 2019

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an extremely rare tumour, which usually affects elderly males and presents in the skin with frequent involvement of the bone-marrow, peripheral blood and lymph nodes. It has a dismal prognosis,...

  • Article
  • Open Access
6 Citations
3,223 Views
7 Pages

Subsequent Malignant Neoplasm of Bone in Children and Adolescent—Possibility of Multimodal Treatment

  • Anna Raciborska,
  • Katarzyna Bilska,
  • Tomasz Koziński and
  • Carlos Rodriguez-Galindo

11 February 2022

Background: In recent years, modifications of treatment protocols introduced in pediatric oncology have resulted in a significant improvement in treatment outcomes. Unfortunately, the probability of subsequent malignant neoplasm (SMN) in this group o...

  • Review
  • Open Access
7 Citations
2,581 Views
13 Pages

Multidisciplinary Approach to the Diagnosis of Occult Primary Neuroendocrine Neoplasm: A Clinical Challenge

  • Roberta Elisa Rossi,
  • Francesca Corti,
  • Sara Pusceddu,
  • Massimo Milione,
  • Jorgelina Coppa,
  • Benedetta Masoni,
  • Simone Oldani,
  • Giovanna Sabella,
  • Pietro Cafaro and
  • Alessandro Repici

25 August 2023

Approximately 11% to 14% of subjects with neuroendocrine neoplasms (NENs) have metastatic lesions with unknown primary origin (UPO), with the majority of UPO-NENs found in the small bowel. Herein, we assessed the available literature on UPO-NENs, foc...

  • Review
  • Open Access
71 Citations
14,108 Views
36 Pages

Intraductal Papillary Neoplasm of Bile Duct: Updated Clinicopathological Characteristics and Molecular and Genetic Alterations

  • Yasuni Nakanuma,
  • Katsuhiko Uesaka,
  • Yuko Kakuda,
  • Takashi Sugino,
  • Keiichi Kubota,
  • Toru Furukawa,
  • Yuki Fukumura,
  • Hiroyuki Isayama and
  • Takuro Terada

9 December 2020

Intraductal papillary neoplasm of the bile duct (IPNB), a pre-invasive neoplasm of the bile duct, is being established pathologically as a precursor lesion of invasive cholangiocarcinoma (CCA), and at the time of surgical resection, approximately hal...

  • Article
  • Open Access
2 Citations
2,479 Views
10 Pages

8 February 2023

There are no studies on treating synchronous head and neck cancer (HNC) and superficial esophageal squamous cell neoplasm (SESCN). We aimed to report the outcomes of endoscopic resection (ER) and no treatment (NT) of SESCN in patients with synchronou...

  • Article
  • Open Access
1,304 Views
10 Pages

Life-Threatening Conditions and Preoperative Complications Associated with Cardiac Neoplasm Do Not Affect Surgical Outcomes or Mortality

  • Kenji Suzuki,
  • Shun-Ichiro Sakamoto,
  • Atsushi Hiromoto,
  • Motohiro Maeda,
  • Takako Yamaguchi,
  • Naoki Yamada,
  • Hitomi Ueda,
  • Takayoshi Matsuyama,
  • Shin-Ichi Osaka and
  • Yosuke Ishii

18 September 2024

Background: Cardiac neoplasms may cause life-threatening symptoms associated with cerebral infarction, ventricular arrhythmias, and heart failure. Emergency surgery or preoperative treatment may be required for these patients. However, no study has r...

  • Review
  • Open Access
12 Citations
5,325 Views
18 Pages

Therapy-Related Myeloid Neoplasm: Biology and Mechanistic Aspects of Malignant Progression

  • Serena Travaglini,
  • Massimiliano Marinoni,
  • Valeria Visconte and
  • Luca Guarnera

Therapy-related myeloid neoplasms (t-MN) arise after a documented history of chemo/radiotherapy as treatment for an unrelated condition and account for 10–20% of myelodysplastic syndromes and acute myeloid leukemia. T-MN are characterized by a...

  • Article
  • Open Access
1 Citations
1,798 Views
19 Pages

A Dual-Feature Framework for Enhanced Diagnosis of Myeloproliferative Neoplasm Subtypes Using Artificial Intelligence

  • Amna Bamaqa,
  • N. S. Labeeb,
  • Eman M. El-Gendy,
  • Hani M. Ibrahim,
  • Mohamed Farsi,
  • Hossam Magdy Balaha,
  • Mahmoud Badawy and
  • Mostafa A. Elhosseini

Myeloproliferative neoplasms, particularly the Philadelphia chromosome-negative (Ph-negative) subtypes such as essential thrombocythemia, polycythemia vera, and primary myelofibrosis, present diagnostic challenges due to overlapping morphological fea...

  • Article
  • Open Access
13 Citations
3,944 Views
11 Pages

Ultrasound-Guided Moving Shot Radiofrequency Ablation of Benign Soft Tissue Neoplasm

  • Wei-Che Lin,
  • Yi-Fan Tai,
  • Meng-Hsiang Chen,
  • Sheng-Dean Luo,
  • Faye Huang,
  • Wei-Chih Chen,
  • Pi-Ling Chiang,
  • Hsiu-Ling Chen,
  • Mei-Hsiu Chen and
  • Jung-Hwan Baek

17 August 2021

Background and Objective: To evaluate the effectiveness of radiofrequency ablation (RFA) using the moving-shot technique for benign soft tissue neoplasm. Materials and Methods: This retrospective study reviewed eight patients with benign soft tissue...

  • Review
  • Open Access
18 Citations
7,802 Views
11 Pages

2 November 2021

Oral malignant melanoma (OMM) is the most common neoplasm of the canine oral cavity. It is characterized by its aggressive local disease as well as its high rate of lymphatic invasion and distant metastasis. OMM carries a poor prognosis, with most pa...

  • Review
  • Open Access
12 Citations
10,898 Views
16 Pages

28 July 2022

Hematopoietic stem cell aging, through the acquisition of somatic mutations, gives rise to clonal hematopoiesis (CH). While a high prevalence of CH has been described in otherwise healthy older adults, CH confers an increased risk of both hematologic...

  • Article
  • Open Access
6 Citations
4,913 Views
14 Pages

Influence of Tea Consumption on the Development of Second Esophageal Neoplasm in Patients with Head and Neck Cancer

  • Yao-Kuang Wang,
  • Wei-Chung Chen,
  • Ying-Ho Lai,
  • Yi-Hsun Chen,
  • Ming-Tsang Wu,
  • Chie-Tong Kuo,
  • Yen-Yun Wang,
  • Shyng-Shiou F. Yuan,
  • Yu-Peng Liu and
  • I-Chen Wu

19 March 2019

Alcohol is an important risk factor for the development of second esophageal squamous-cell carcinoma (ESCC) in head and neck squamous-cell carcinoma (HNSCC) patients. However, the influence of tea consumption is uncertain. We prospectively performed...

  • Review
  • Open Access
3 Citations
2,953 Views
14 Pages

Blastic Plasmacytoid Dendritic Cell Neoplasm, from a Dermatological Point of View

  • Cosimo Di Raimondo,
  • Flavia Lozzi,
  • Pier Paolo Di Domenico,
  • Claudia Paganini,
  • Elena Campione,
  • Marco Galluzzo and
  • Luca Bianchi

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematological malignancy derived from the precursors of plasmacytoid dendritic cells. Although disease awareness has increased over time, BPDCN represents a rare disease with an ag...

  • Review
  • Open Access
10 Citations
3,731 Views
11 Pages

Blastic Plasmocytoid Dendritic Cell Neoplasm (BPDCN): Clinical Features and Histopathology with a Therapeutic Overview

  • Gerardo Cazzato,
  • Marialessandra Capuzzolo,
  • Emilio Bellitti,
  • Giovanni De Biasi,
  • Anna Colagrande,
  • Katia Mangialardi,
  • Francesco Gaudio and
  • Giuseppe Ingravallo

8 December 2023

Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCNs) are a rare, highly aggressive hematological malignant neoplasm that primarily involve the skin, bone marrow, lymph nodes and even extra-nodal sites. The rarity and relative poor description of ca...

  • Case Report
  • Open Access
2 Citations
3,377 Views
6 Pages

Oncocytic adrenal cortical neoplasms are rare cases and are divided into oncocytoma, oncocytic neoplasms of uncertain malignant potential and oncocytic adrenal cortical carcinomas, based on the Lin–Weiss–Bisceglia (LWB) histological syste...

  • Article
  • Open Access
1,495 Views
14 Pages

22 July 2025

Background: Genetic alterations in CSF3R, typically associated with chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML), rarely occur in other myeloid neoplasms. Methods: This study characterized the clinical, morphologic...

  • Article
  • Open Access
11 Citations
3,877 Views
10 Pages

Pro-Gastrin-Releasing Peptide as a Biomarker in Lung Neuroendocrine Neoplasm

  • Violetta Rosiek,
  • Angelika Kogut and
  • Beata Kos-Kudła

22 June 2023

There is a lack of effective biomarkers for diagnosing lung neuroendocrine neoplasms (LNENs). A known small cell lung cancer (SCLC) biomarker is a pro-gastrin-releasing peptide (ProGRP), but not for all LNENs, especially for bronchopulmonary carcinoi...

  • Proceeding Paper
  • Open Access
102 Views
10 Pages

An Automated Medical Diagnosis System for Neoplasm Medical Image Classification Using Supervised and Unsupervised Techniques

  • Sreedhar Kumar Seetharaman,
  • Basant Kumar,
  • Manjunath Chikkanjinappa Rajanna and
  • Syed Thouheed Ahmed

11 February 2026

In this research, an improved automated medical prediction system, namely, the Neoplasm Medical Image Classification System (NMICS), is proposed. The proposed NMICS aims to robotically identify whether the given test magnetic resonance image (MRI) be...

  • Review
  • Open Access
3 Citations
2,303 Views
17 Pages

Prognostic Assessment of Gastropancreatic Neuroendocrine Neoplasm: Prospects and Limits of Radiomics

  • Federica De Muzio,
  • Fabio Pellegrino,
  • Roberta Fusco,
  • Salvatore Tafuto,
  • Mariano Scaglione,
  • Alessandro Ottaiano,
  • Antonella Petrillo,
  • Francesco Izzo and
  • Vincenza Granata

7 September 2023

Neuroendocrine neoplasms (NENs) are a group of lesions originating from cells of the diffuse neuroendocrine system. NENs may involve different sites, including the gastrointestinal tract (GEP-NENs). The incidence and prevalence of GEP-NENs has been c...

  • Review
  • Open Access
9 Citations
3,553 Views
12 Pages

Thyroid-Bed Schwannoma Mimicking a Thyroid Neoplasm: A Challenging Diagnosis: Report of a Case and Literature Review

  • Claudio Gambardella,
  • Ludovico Docimo,
  • Giancarlo Candela,
  • Giovanni Cozzolino,
  • Federico Mongardini,
  • Francesca Serilli,
  • Giusiana Nesta,
  • Marcello Filograna Pignatelli,
  • Sonia Ferrandes and
  • Giovanni Docimo
  • + 1 author

24 September 2022

Background: Schwannomas, also called neurinomas, are rare benign tumors of the neural cells that can develop from the sheaths of nervous structures of several districts, although the most frequent sites are the cranial nerves (25%–45%). Rarely,...

  • Article
  • Open Access
4 Citations
2,013 Views
14 Pages

Contrast-Enhanced Harmonic Endoscopic Ultrasound for Diagnosis of the Aggressiveness of Pancreatic Neuroendocrine Neoplasm

  • Takashi Tamura,
  • Yuto Sugihara,
  • Hirofumi Yamazaki,
  • Hiromu Koutani,
  • Takaaki Tamura,
  • Ikuhisa Tsuda,
  • Tomoya Emori,
  • Yuki Kawaji,
  • Keiichi Hatamaru and
  • Masayuki Kitano
  • + 3 authors

29 November 2022

The purpose of this study is to clarify the associations between the enhancement patterns on contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) and the aggressiveness and prognosis of pancreatic neuroendocrine neoplasms (PanNENs). Patients who...

  • Interesting Images
  • Open Access
334 Views
6 Pages

Low-grade appendiceal mucinous neoplasms (LAMNs) are uncommon epithelial tumors that frequently present with symptoms indistinguishable from acute appendicitis, yet may progress to pseudomyxoma peritonei with significant long-term morbidity. We repor...

  • Review
  • Open Access
23 Citations
7,434 Views
25 Pages

Myelodysplastic neoplasm (MDS) represents a heterogeneous group of myeloid disorders that originate from the hematopoietic stem and progenitor cells that lead to the development of clonal hematopoiesis. MDS was characterized by an increased risk of t...

  • Article
  • Open Access
3 Citations
7,339 Views
16 Pages

Navigating Intraductal Papillary Mucinous Neoplasm Management through Fukuoka Consensus vs. European Evidence-Based Guidelines on Pancreatic Cystic Neoplasms—A Study on Two European Centers

  • Vladimir Djordjevic,
  • Djordje Knezevic,
  • Blaz Trotovsek,
  • Ales Tomazic,
  • Miha Petric,
  • Benjamin Hadzialjevic,
  • Nikica Grubor and
  • Mihajlo Djokic

6 June 2024

This study addresses the critical need for the accurate diagnosis and management of intraductal papillary mucinous neoplasms (IPMNs), which are pancreatic cystic neoplasm types holding a substantial potential for malignancy. It evaluates the diagnost...

  • Case Report
  • Open Access
3 Citations
4,412 Views
11 Pages

Mucinous Cystic Neoplasm of Pancreas in a Pregnant Woman Presenting with Severe Anemia and Gastric Bleeding: Case Report and Review of the Literature

  • Susan Farahmandi,
  • Mohamed Elessawy,
  • Dirk O. Bauerschlag,
  • Ulrich Pecks,
  • Samir Abdullazade,
  • Jan Henrik Beckmann,
  • Thorsten Heilmann,
  • Anna-Lena Rumpf,
  • Nicolai Maass and
  • Vincent Winkler
  • + 1 author

Mucinous cystic neoplasms of the pancreas are uncommon and especially their occurrence during pregnancy is an extremely rare event which necessitates an individualized and interdisciplinary management. A 33-year old woman was referred to our departme...

  • Article
  • Open Access
3 Citations
2,784 Views
15 Pages

Validation of Artificial Intelligence Computer-Aided Detection on Gastric Neoplasm in Upper Gastrointestinal Endoscopy

  • Hannah Lee,
  • Jun-Won Chung,
  • Sung-Cheol Yun,
  • Sung Woo Jung,
  • Yeong Jun Yoon,
  • Ji Hee Kim,
  • Boram Cha,
  • Mohd Azzam Kayasseh and
  • Kyoung Oh Kim

30 November 2024

Background/Objectives: Gastric cancer ranks fifth for incidence and fourth in the leading causes of mortality worldwide. In this study, we aimed to validate previously developed artificial intelligence (AI) computer-aided detection (CADe) algorithm,...

  • Article
  • Open Access
6 Citations
3,466 Views
13 Pages

Preliminary Study: Proteomic Profiling Uncovers Potential Proteins for Biomonitoring Equine Melanocytic Neoplasm

  • Parichart Tesena,
  • Amornthep Kingkaw,
  • Wanwipa Vongsangnak,
  • Surakiet Pitikarn,
  • Narumon Phaonakrop,
  • Sittiruk Roytrakul and
  • Attawit Kovitvadhi

27 June 2021

Equine melanocytic neoplasm (EMN) is a cutaneous neoplasm and is mostly observed in aged grey horses. This preliminary study aimed to identify potential proteins to differentiate normal, mild and severe EMN from serum proteomic profiling. Serum sampl...

  • Review
  • Open Access
10 Citations
6,658 Views
20 Pages

The Role of MRI in the Diagnosis of Solid Pseudopapillary Neoplasm of the Pancreas and Its Mimickers: A Case-Based Review with Emphasis on Differential Diagnosis

  • Jelena Djokic Kovac,
  • Aleksandra Djikic-Rom,
  • Aleksandar Bogdanovic,
  • Aleksandra Jankovic,
  • Nikica Grubor,
  • Goran Djuricic and
  • Vladimir Dugalic

Solid pseudopapillary neoplasm (SPN) is rare pancreatic tumor occurring most commonly in young females. The typical imaging appearance of SPN is of well-defined, encapsulated, and large heterogeneous tumors, consisting of solid and cystic components...

  • Article
  • Open Access
8 Citations
2,507 Views
13 Pages

14 February 2023

The long-term effect of Helicobacter pylori eradication on metachronous gastric neoplasm prevention after endoscopic submucosal dissection (ESD) of gastric adenoma is unclear. This study included patients with confirmed H. pylori infection after ESD...

  • Article
  • Open Access
7 Citations
3,260 Views
13 Pages

Inheritance and Expressivity of Neoplasm Trait in Crosses between the Domestic Pea (Pisum sativum subsp. sativum) and Tall Wild Pea (Pisum sativum subsp. elatius)

  • Hatice Sari,
  • Duygu Sari,
  • Tuba Eker,
  • Bilal Aydinoglu,
  • Huseyin Canci,
  • Cengiz Ikten,
  • Ramazan S. Gokturk,
  • Ahmet Zeybek,
  • Melike Bakir and
  • Cengiz Toker
  • + 1 author

27 November 2020

The Neoplasm trait in pea pods is reported to be due to the lack of ultraviolet (UV) light in glasshouse conditions or in response to pea weevil (Bruchus pisorum L.) damage. This pod deformation arises from the growth of non-meristematic tissue on po...

  • Article
  • Open Access
3 Citations
2,274 Views
13 Pages

30 September 2022

Objectives: To create a novel preoperative prediction model based on a deep learning algorithm to predict neoplasm T staging and grading in patients with upper tract urothelial carcinoma (UTUC). Methods: We performed a retrospective cohort study of p...

  • Article
  • Open Access
33 Citations
4,182 Views
12 Pages

Integrated Clinical Genotype-Phenotype Characteristics of Blastic Plasmacytoid Dendritic Cell Neoplasm

  • C. Cameron Yin,
  • Naveen Pemmaraju,
  • M. James You,
  • Shaoying Li,
  • Jie Xu,
  • Wei Wang,
  • Zhenya Tang,
  • Omar Alswailmi,
  • Kapil N. Bhalla and
  • Joseph D. Khoury
  • + 2 authors

23 November 2021

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive neoplasm derived from plasmacytoid dendritic cells. While advances in understanding the pathophysiology of the disease have been made, integrated systematic analyses of the sp...

  • Review
  • Open Access
7 Citations
2,925 Views
11 Pages

Effect of Neuroendocrine Neoplasm Treatment on Human Reproductive Health and Sexual Function

  • Virginia Zamponi,
  • Anna La Salvia,
  • Maria Grazia Tarsitano,
  • Nevena Mikovic,
  • Maria Rinzivillo,
  • Francesco Panzuto,
  • Elisa Giannetta,
  • Antongiulio Faggiano and
  • Rossella Mazzilli

8 July 2022

Neuroendocrine neoplasms (NEN) are characterized by a wide clinical heterogeneity and biological variability, with slow progression and long survival in most cases. Although these tumors can affect young adults, there are few studies that focus on th...

  • Article
  • Open Access
4 Citations
3 Pages

Several studies have shown that thrombotic events may underlie a latent or subclinical myeloproliferative neoplasm (MPN) and precede its definite diagnosis by 1–2 years. An early diagnosis of patients with MPN, especially those with thrombotic events...

  • Article
  • Open Access
9 Citations
2,319 Views
15 Pages

Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas

  • Jasmina Kuvendjiska,
  • Felix Müller,
  • Peter Bronsert,
  • Sylvia Timme-Bronsert,
  • Stefan Fichtner-Feigl and
  • Birte Kulemann

15 July 2023

Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cyst and a precursor of pancreatic cancer (PDAC). Since PDAC has a devastatingly high mortality rate, the early diagnosis and treatment of any precursor lesion are rational....

  • Article
  • Open Access
3 Citations
2,730 Views
16 Pages

The Genomic Landscape in Philadelphia-Negative Myeloproliferative Neoplasm Patients with Second Cancers

  • Chia-Chen Hsu,
  • Ying-Hsuan Wang,
  • Yi-Yang Chen,
  • Ying-Ju Chen,
  • Chang-Hsien Lu,
  • Yu-Ying Wu,
  • Yao-Ren Yang,
  • Hsing-Yi Tsou,
  • Chian-Pei Li and
  • Chih-Cheng Chen
  • + 1 author

14 July 2022

Patients with myeloproliferative neoplasms (MPNs) are characterized by systemic inflammation. With the indolent nature of the diseases, second cancers (SCs) have emerged as a challenging issue in afflicted patients. Epidemiological studies have confi...

  • Systematic Review
  • Open Access
1,535 Views
19 Pages

Optimizing Stereotactic Intracranial Neoplasm Treatment: A Systematic Review of PET Integration with Gamma Knife Radiosurgery

  • Robert C. Subtirelu,
  • Eric M. Teichner,
  • Milo Writer,
  • Kevin Bryan,
  • Shiv Patil,
  • Talha Khan,
  • Lancelot Herpin,
  • Raj N. Patel,
  • Emily Christner and
  • Mona-Elisabeth Revheim
  • + 3 authors

10 July 2025

Objective: Traditional imaging modalities for the planning of Gamma Knife radiosurgery (GKRS) are non-specific and do not accurately delineate intracranial neoplasms. This study aimed to evaluate the utility of positron emission tomography (PET) for...

  • Article
  • Open Access
9 Citations
3,757 Views
15 Pages

Endoscopic Features of Gastric Epithelial Neoplasm of Fundic Gland Mucosa Lineage

  • Kohei Matsumoto,
  • Hiroya Ueyama,
  • Takashi Yao,
  • Tomoyo Iwano,
  • Momoko Yamamoto,
  • Hisanori Utsunomiya,
  • Ryota Uchida,
  • Daiki Abe,
  • Shotaro Oki and
  • Akihito Nagahara
  • + 8 authors

2 November 2022

The endoscopic features of gastric epithelial neoplasms of fundic gland mucosa lineage (GEN-FGML) have not been well investigated. We aimed to clarify the endoscopic features of GEN-FGML and differences between gastric adenocarcinoma of the fundic gl...

  • Article
  • Open Access
3 Citations
4,687 Views
16 Pages

Faecal Proteomics and Functional Analysis of Equine Melanocytic Neoplasm in Grey Horses

  • Parichart Tesena,
  • Amornthep Kingkaw,
  • Narumon Phaonakrop,
  • Sittiruk Roytrakul,
  • Paviga Limudomporn,
  • Wanwipa Vongsangnak and
  • Attawit Kovitvadhi

21 February 2022

Equine melanocytic neoplasm (EMN) is a common disease in older grey horses. The purpose of this study was to examine the potential proteins throughout EMN stages from faecal proteomic outlining using functional analysis. Faecal samples were collected...

  • Case Report
  • Open Access
3 Citations
2,287 Views
9 Pages

ETV6::ABL1-Positive Myeloid Neoplasm: A Case of a Durable Response to Imatinib Mesylate without Additional or Previous Treatment

  • Maria Teresa Bochicchio,
  • Giovanni Marconi,
  • Carmen Baldazzi,
  • Lorenza Bandini,
  • Francesca Ruggieri,
  • Alessandro Lucchesi,
  • Claudio Agostinelli,
  • Elena Sabattini,
  • Agnese Orsatti and
  • Gianantonio Rosti
  • + 6 authors

21 December 2023

ETV6::ABL1 rearranged neoplasms are rare hematological diseases. To date, about 80 cases have been reported, including myeloid and lymphoid leukemias. The ETV6 gene codes for an ETS family transcription factor and several fusion partners have been de...

  • Review
  • Open Access
8 Citations
6,058 Views
13 Pages

7 October 2021

We present histopathological criteria for diagnosing keratoacanthoma (KA). In KA, four histological stages are recognized, which are the early/proliferative stage, well-developed stage, regressing stage and regressed stage. In diagnosing KA, we empha...

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