Search Results (6)

The present study examined the impact of skill level on the integration of contextual prior information and kinematic information alongside post-error adjustment during action anticipation in basketball. Twenty-three collegiate basketball players and twenty-three control participants engaged in anticipating as quickly and accurately as possible the outcomes of free throws, utilizing video clips depicting basketball players’ actions, both with and without contextual prior information. Anticipatory performance and the difference in anticipatory performance following errors and correct responses were analyzed based on skill level and the congruency of contextual prior information (none, congruent, and incongruent). The findings revealed that the congruency of contextual prior information significantly affects action anticipation, with skill level moderating this effect. Moreover, skill level influenced the congruency effect on accuracy discrepancies between post-error and post-correct trials during action anticipation, with controls showing greater sensitivity to previous trial performance compared to experts. These results provide further evidence for the notion that individuals employ Bayesian reliability-based strategies to integrate different information sources and underscore the role of skill level in adjusting anticipatory judgments following errors during action anticipation. These insights contribute to a deeper understanding of the cognitive and behavioral mechanisms that differentiate skill levels in action anticipation, potentially guiding the development of targeted training interventions. Full article

The financing function of land in China has been extensively documented, but little research has explored the role of land finance in the real estate market affecting local government debt. In light of the recent simultaneous increase in China’s real estate market risk and local government debt risk over the past two years, a pressing need to reevaluate the significance of land finance has arisen. Thus, this study explores the role of land finance in the relationship between the real estate market and local debt risk. The data were collected from 224 Chinese cities from 2010 to 2019. The study found that real estate market prosperity significantly promotes the expansion of local government debt. Land finance acts as a mediator and a moderator in this relationship. The study also found that during periods of real estate market booms, local governments tend to sell more land, which reinforces their debt-raising behavior and exacerbates the impact of the real estate market on local government debt; during periods of real estate market downturns, local governments tend to decrease debt, but the government debt repayment risk increases significantly. Furthermore, the amplifying effect of land finance is more pronounced in economically developed regions and cities with higher public budget revenues. Full article

Hard brittle materials such as ceramics and crystals are commonly utilized in various industries, including information technology, mechanical engineering, and semiconductors. These materials, known for their high brittleness and hardness but low fracture toughness, pose challenges in efficient and high-quality machining. Current abrasive machining techniques involve rough grinding, fine grinding, and polishing processes, with the latter being the most time-consuming and accounting for over half of the total machining time. Improving processing parameters in rough and fine grinding can increase machining efficiency, reduce surface and subsurface damage, and improve workpiece quality, ultimately reducing the polishing time. This paper explores the abrasive scratching of hard brittle materials, examining the nucleation and propagation of cracks causing surface and subsurface damage, and the underlying mechanisms. The research provides suggestions for enhancing abrasive machining efficiency and ensuring the surface quality of hard brittle materials. Full article

Bacillus subtilis is a gram-positive bacterium, a promising microorganism due to its strong extracellular protein secretion ability, non-toxic, and relatively mature industrial fermentation technology. However, cell autolysis during fermentation restricts the industrial application of B. subtilis. With the fast advancement of molecular biology and genetic engineering technology, various advanced procedures and gene editing tools have been used to successfully construct autolysis-resistant B. subtilis chassis cells to manufacture various biological products. This paper first analyses the causes of autolysis in B. subtilis from a mechanistic perspective and outlines various strategies to address autolysis in B. subtilis. Finally, potential strategies for solving the autolysis problem of B. subtilis are foreseen. Full article

The Eurasian avian-like swine (EA) H1N1 virus has affected the Chinese swine industry, and human infection cases have been reported occasionally. However, little is known about the pathogenic mechanism of EA H1N1 virus. In this study, we compared the mouse pathogenicity of A/swine/Guangdong/YJ4/2014 (YJ4) and A/swine/Guangdong/MS285/2017 (MS285) viruses, which had similar genotype to A/Hunan/42443/2015 (HuN-like). None of the mice inoculated with 10⁶ TCID₅₀ of YJ4 survived at 7 days post infection, while the survival rate of the MS285 group was 100%. Therefore, a series of single fragment reassortants in MS285 background and two rescued wild-type viruses were generated by using the reverse genetics method, and the pathogenicity analysis revealed that the PB2 gene contributed to the high virulence of YJ4 virus. Furthermore, there were 11 amino acid differences in PB2 between MS285 and YJ4 identified by sequence alignment, and 11 single amino acid mutant viruses were generated in the MS285 background. We found that the R251K mutation significantly increased the virulence of MS285 in mice, contributed to high polymerase activity and enhanced viral genome transcription and replication. These results indicate that PB2-R251K contributes to the virulence of the EA H1N1 virus and provide new insight into future molecular epidemiological surveillance strategies. Full article

The moss Physcomitrella patens is a model system for studying plant developmental processes. ABSCISIC ACID INSENSITIVE3 (ABI3), a transcription factor of the ABA signaling pathway, plays an important role in plant growth and development in vascular plant. To understand the regulatory mechanism of ABA and PpABI3 on vegetative development in Physcomitrella patens, we applied physiological, cellular, and RNA-seq analyses in wild type (WT) plants and ∆abi3 mutants. During ABA treatment, the growth of gametophytes was inhibited to a lesser extent ∆abi3 plants compared with WT plants. Microscopic observation indicated that the differentiation of caulonemata from chloronemata was accelerated in ∆abi3 plants when compared with WT plants, with or without 10 μM of ABA treatment. Under normal conditions, auxin concentration in ∆abi3 plants was markedly higher than that in WT plants. The auxin induced later differentiation of caulonemata from chloronemata, and the phenotype of ∆abi3 plants was similar to that of WT plants treated with exogenous indole-3-acetic acid (IAA). RNA-seq analysis showed that the PpABI3-regulated genes overlapped with genes regulated by the ABA treatment, and about 78% of auxin-related genes regulated by the ABA treatment overlapped with those regulated by PpABI3. These results suggested that ABA affected vegetative development partly through PpABI3 regulation in P. patens; PpABI3 is a negative regulator of vegetative development in P. patens, and the vegetative development regulation by ABA and PpABI3 might occur by regulating the expression of auxin-related genes. PpABI3 might be associated with cross-talk between ABA and auxin in P. patens. Full article