Naegleria fowleri and Emerging Amoebic Infections
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366).
Deadline for manuscript submissions: 31 March 2026 | Viewed by 67
Special Issue Editors
Interests: immunology; molecular biology; virulence factors; host–pathogen interaction; Naegleria fowleri
Interests: Naegleria fowleri; vaccines; immunological memory; mucosal immunology; bioinformatics tools
Special Issue Information
Dear Colleagues,
Emerging amoebic infections, such as Naegleria fowleri, pose a significant global health risk, as their trophozoites can be found in various natural aquatic habitats, such as rivers, lakes, and streams. This amoebic species is responsible for Primary Amoebic Meningoencephalitis (PAM), a disease with a mortality rate exceeding 95%. The high mortality rate is largely due to a lack of awareness about the disease, which can often lead to misdiagnosis. PAM may be confused with other infectious diseases, delaying proper treatment. Additionally, there has been a global trend indicating an increase in the number of PAM cases. This increase is potentially linked to rising temperatures caused by global warming, as the amoeba trophozoites prefer warmer waters, enabling their rapid reproduction.
This Special Issue invites articles that focus on the study of emerging amoebic infections such as Naegleria fowleri. These infections present various challenges such as the understanding of the current distribution of amoebas and the epidemiology of the diseases they cause, where establishing accurate incidence and prevalence rates is crucial. We also aim to develop prevention strategies, including raising awareness among vulnerable populations about the risks of infection, and establishing knowledge to support the generation of effective vaccines. Additionally, enhancing our understanding of these infections is essential for improving timely diagnoses and innovative treatments.
Dr. María Maricela Carrasco-Yépez
Dr. Saúl Rojas-Hernández
Guest Editors
Manuscript Submission Information
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Keywords
- amoebic infections
- Naegleria fowleri
- epidemiology-surveillance
- molecular biology
- immunology-vaccines
- opportune diagnosis
- innovative treatments
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