New Strategies for the Diagnosis, Treatment and Risk Assessment of Parasitic Disease

Special Issue Editors


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Guest Editor
Institute of Biological Sciences, Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Brazil
Interests: schistosomiasis; leishmaniasis; parasitic diseases; immune response; coinfections

E-Mail Website
Guest Editor
Institute of Biological Sciences, Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Brazil
Interests: schistosomiasis; strongyloidiasis; immune response induced by helminthic infections; immunomodulatory effect of helminths; diagnosis

E-Mail Website
Guest Editor
Department of Biology, Federal Institute of Education, Science and Technology of Maranhão, São Raimundo das Mangabeiras, Brazil
Interests: helminthology; schistosomiasis; parasitic diseases; immune response

Special Issue Information

Dear Colleagues,

Parasitic diseases affect over a billion people worldwide, particularly in the poorest regions, where access to housing, healthcare and sanitation is most limited. These diseases can be transmitted via vectors or contaminating soil, water, and food. Parasitic diseases induce high mortality and morbidity, particularly in cases without proper diagnosis and treatment. In addition, some parasites can infect both humans and other animals, making it harder to control transmission. Therefore, all these aspects constitute risk factors associated with parasitic diseases and interfere with control measures.

Despite the World Health Organization's efforts to control parasitic diseases globally, significant challenges stand in the way of eliminating such diseases as a public health problem. Among them, it is important to mention the existence of drug-resistant parasites, a shortage of accurate epidemiological data on the transmission of parasitic diseases, a lack of sensitive and specific diagnostic tools for many parasitic infections, the need for new antiparasitic drugs, limited non-invasive biomarkers to measure disease severity, and, in some cases, the involvement of wild and livestock parasite reservoirs.

On this account, this Special Issue aims to gather a collection of high-quality scientific articles that present innovative approaches to address these aspects of host–parasite interactions. The submission of original basic research articles and reviews is encouraged.

Dr. Genil Camelo
Dr. Déborah Aparecida Negrão-Corrêa
Dr. Guilherme Silva Miranda
Guest Editors

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Keywords

  • ethnopharmacology
  • epidemiological survey
  • drug repositioning
  • wild reservoirs
  • risk factors
  • host–parasite interactions
  • biomarkers
  • drug targets
  • immune response
  • one health

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Published Papers (1 paper)

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Research

8 pages, 219 KiB  
Article
Baylisascaris procyonis (Chromadorea Ascarididae): Case Study of the Little-Known Human Health Threat That Is Literally in Your Backyard
by Scott E. Henke
Trop. Med. Infect. Dis. 2025, 10(6), 156; https://doi.org/10.3390/tropicalmed10060156 - 2 Jun 2025
Viewed by 623
Abstract
Baylisascariasis is a debilitating and potentially lethal zoonotic disease caused by a nematode parasite that has a worldwide distribution. Baylisascaris spp. are carried by a variety of mammalian definitive hosts, and their larvae can infect a large diversity of paratenic hosts including birds [...] Read more.
Baylisascariasis is a debilitating and potentially lethal zoonotic disease caused by a nematode parasite that has a worldwide distribution. Baylisascaris spp. are carried by a variety of mammalian definitive hosts, and their larvae can infect a large diversity of paratenic hosts including birds and mammals, and even humans. Herein, the potential exposure risk of this zoonotic parasite is demonstrated through the study of a suburban American community with a population of Baylisascaris procyonis—infected raccoons (Procyon lotor) as a case study for any location with Baylisascaris spp., definitive hosts, and proximity to humans. Soil from 100 properties within neighborhoods of southern Corpus Christi, TX, USA, was surveyed to determine if viable B. procyonis eggs were present. In total, 27% of the residential properties were contaminated. Positive soil samples, on average, contained 31,287 B. procyonis eggs/gram of soil; of these samples, 92% of the B. procyonis eggs had motile larvae. Sites with contaminated soils appeared random within residential properties; frequency of contaminated sites was similar between known raccoon defecation sites and random sites. Suggestions for the reduction in risks of exposure to this potentially debilitating parasite are offered to residents of Baylisascaris-contaminated properties. Full article
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