Substance Use Disorder: Molecular Basis and Therapeutics
A special issue of NeuroSci (ISSN 2673-4087).
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 3913
Special Issue Editor
Special Issue Information
Dear Colleagues,
Neuropsychiatric conditions significantly contribute towards global disease burden, and substance use disorders (SUDs) make up the second-largest proportion of this burden after depression. SUDs describe both the use of illegal or illicit substances and the misuse of legal substances such as alcohol, nicotine, or prescription drugs. SUD or addiction is a complex polygenic psychiatric condition involving various brain regions, proteins, and physiological effects encompassing diverse etiologies. The similarity of the pharmacological and behavioral effects of structurally diverse drugs may be explained by the fact that each drug, despite its many distinct actions in the brain, converges to produce some common outcomes by activating the reward circuits in the brain. An ever-increasing number of neuroscientists are searching for clues regarding the molecular determinants of addictive behavior, and considerable progress has been made in identifying the molecular and cellular mechanisms underlying addictive behavior, including dependence, tolerance, and withdrawal.
This Special Issue focuses on understanding the molecular and cellular mechanisms underlying SUDs. We welcome reviews, short communications, and original research articles that shed light on the neurological effects of substance abuse as well as novel psychosocial and therapeutic strategies for alcohol, cannabis, cocaine, opiate, and polysubstance abuse and dependence treatments.
Dr. Piyusha P. Pagare
Guest Editor
Manuscript Submission Information
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Keywords
- opioid use disorder
- alcohol
- drug abuse
- nicotine
- marijuana
- stimulants
- hallucinogens
- addiction
- dependence
- treatment
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