Microarrays for Drug Discovery and Development
A special issue of BioTech (ISSN 2673-6284).
Deadline for manuscript submissions: closed (31 March 2017) | Viewed by 198
Special Issue Information
Dear Colleagues,
The diversity of microarrays and their technological advantages have gained importance in the solving of different problems at the early stages of Drug Discovery and Development (DDD), ranging from high-throughput screening of compound libraries to preclinical assays. Recent discovery of new target-specific leads and the development of disease-specific companion diagnostics are promising examples where microarrays might become indispensable tools for DDD. Moreover, cost-effective microarray applications provide the unique opportunity to create multifaceted pipelines with aim to reduce expenditures on DDD projects, an important challenge since some time.
This Special Issue will focus on microarray researches leading to discovery and development of therapeutic molecules, as small compounds, antibodies, proteins, peptides, and aptamers. You are invited to submit original papers and reviews describing screening of natural and chemical compound libraries, profiling protein expression and post-translational modification in cells exposed to pharmacophores, multiplex assays for target discovery or drug validation, and approaches for data mining. Contribution of microarrays to pharmacogenomics and pharmacoproteomics, including assessment of toxicity and other absorption, distribution, metabolism, and excretion (ADME) parameters with a perspective to improve the outcome of discovery projects, and to help in decision making regarding drug candidates for clinical assays, are also welcome.
Prof. Dr. Vehary Sakanyan
Guest Editor
Manuscript Submission Information
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Keywords
- drug discovery
- drug development
- microarrays
- high-throughput screening
- drug validation
- pharmacogenomics
- pharmacoproteomics
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