The “Cell Signaling” Section of Cells (ISSN: 2073-4409) aims to stimulate research that focuses on the understanding of cell signaling in evolution, development, physiology, health, and disease. We welcome manuscripts, including original research, review articles, communications, and technical notes, that emphasize signaling networks governing all aspects of cell signaling, including mechanisms and control of receptor signaling and regulation of all aspects of cell function, including growth, proliferation, differentiation survival, gene expression, metabolism, and trafficking.

You have free and unlimited access to the full texts of all of the open-access articles published in our journal. We welcome you to read our most highly cited papers published in 2024 below:

1. “Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview”
by Isabelle Dias Da Silva, Vincent Wuidar, Manon Zielonka and Christel Pequeux
Cells 2024, 13(15), 1236; https://doi.org/10.3390/cells13151236
Available online: https://www.mdpi.com/2073-4409/13/15/1236

2. “Cancer Drug Resistance: Targeting Proliferation or Programmed Cell Death”
by Elena V. Sazonova, Maria A. Yapryntseva, Nikolay V. Pervushin, Roman I. Tsvetcov, Boris Zhivotovsky and Gelina S. Kopeina
Cells 2024, 13(5), 388; https://doi.org/10.3390/cells13050388
Available online: https://www.mdpi.com/2073-4409/13/5/388

3. “Hippo Signaling at the Hallmarks of Cancer and Drug Resistance”
by Ramesh Kumar and Wanjin Hong
Cells 2024, 13(7), 564; https://doi.org/10.3390/cells13070564
Available online: https://www.mdpi.com/2073-4409/13/7/564

4. “Campylobacter jejuni Surface-Bound Protease HtrA, but Not the Secreted Protease nor Protease in Shed Membrane Vesicles, Disrupts Epithelial Cell-to-Cell Junctions”
by Irshad Sharafutdinov, Nicole Tegtmeyer, Manfred Rohde, Annelie Olofsson, Zia ur Rehman, Anna Arnqvist and Steffen Backert
Cells 2024, 13(3), 224; https://doi.org/10.3390/cells13030224
Available online: https://www.mdpi.com/2073-4409/13/3/224

5. “The Multifaceted Role of miR-21 in Pancreatic Cancers”
by Clare Chen, Lusine Demirkhanyan and Christopher S. Gondi
Cells 2024, 13(11), 948; https://doi.org/10.3390/cells13110948
Available online: https://www.mdpi.com/2073-4409/13/11/948

6. “Oxidative Stress and the Nrf2/PPARγ Axis in the Endometrium: Insights into Female Fertility”
by Peter Artimovič, Zuzana Badovská, Silvia Toporcerová, Ivana Špaková, Lukáš Smolko, Gabriela Sabolová, Eva Kriváková and Miroslava Rabajdová
Cells 2024, 13(13), 1081; https://doi.org/10.3390/cells13131081
Available online: https://www.mdpi.com/2073-4409/13/13/1081

7. “Secretome from Magnetically Stimulated Muscle Exhibits Anticancer Potency: Novel Preconditioning Methodology Highlighting HTRA1 Action”
by Yee Kit Tai, Jan Nikolas Iversen, Karen Ka Wing Chan, Charlene Hui Hua Fong, Rafhanah Banu Abdul Razar, Sharanya Ramanan, Lye Yee Jasmine Yap, Jocelyn Naixin Yin, Shi Jie Toh, Craig Jun Kit Wong et al.
Cells 2024, 13(5), 460; https://doi.org/10.3390/cells13050460
Available online: https://www.mdpi.com/2073-4409/13/5/460

8. “Breaking Bad Proteins—Discovery Approaches and the Road to Clinic for Degraders”
by Corentin Bouvier, Rachel Lawrence, Francesca Cavallo, Wendy Xolalpa, Allan Jordan, Roland Hjerpe and Manuel S. Rodriguez.
Cells 2024, 13(7), 578; https://doi.org/10.3390/cells13070578
Available online: https://www.mdpi.com/2073-4409/13/7/578

9. “Calcium Deregulation in Neurodegeneration and Neuroinflammation in Parkinson’s Disease: Role of Calcium-Storing Organelles and Sodium–Calcium Exchanger”
by Guendalina Bastioli, Silvia Piccirillo, Laura Graciotti, Marianna Carone, Giorgia Sprega, Omayema Taoussi, Alessandra Preziuso and Pasqualina Castaldo
Cells 2024, 13(15), 1301; https://doi.org/10.3390/cells13151301
Available online: https://www.mdpi.com/2073-4409/13/15/1301

10. “Discrete Mechanistic Target of Rapamycin Signaling Pathways, Stem Cells, and Therapeutic Targets”
by Meena Jhanwar-Uniyal, Sabrina L. Zeller, Eris Spirollari, Mohan Das, Simon J. Hanft and Chirag D. Gandhi
Cells 2024, 13(5), 409; https://doi.org/10.3390/cells13050409
Available online:  https://www.mdpi.com/2073-4409/13/5/409