Anatomia, Volume 4, Issue 4 (December 2025) – 3 articles

Background: Social networking platforms offer promising educational value, particularly for undergraduate students whose daily lives are deeply embedded in online spaces. Yet in most courses, instructional technologies remain limited to institutional learning management systems (LMSs), which often do not foster informal interaction or community. This study examined whether supplementing LMSs with a Facebook group could enhance academic outcomes and retention in undergraduate Anatomy and Physiology (A&P) courses. Methods: Over two semesters, two student cohorts (n = 39) were taught by the same instructor using identical materials; one cohort also used a closed Facebook group for course-related engagement. Results: While final course grades were not significantly different between groups (p = 0.186), students in the Facebook cohort scored significantly higher on mid-semester unit exams (p < 0.001 to p = 0.006). Regression analysis revealed a 9.4% higher mean final course grade among Facebook users. Importantly, the pass rate in the Facebook cohort was 94.7% compared to 45.0% in the control group, with dropout rates significantly lower (5.3% vs. 55%, p = 0.001). Conclusions: These findings suggest that incorporating social media into undergraduate science instruction may promote academic success and retention by providing a familiar, collaborative space for active learning and peer support. Full article

Background/Objectives: This article discusses the clinical–surgical relevance of vascular anatomical variations, such as fenestrations—the division of a vessel into multiple channels that subsequently rejoin distally. Although rare in peripheral veins, these variations, which originate from the incomplete condensation of the embryonic capillary plexus, can predispose thrombosis and necessitate preoperative recognition to avert complications during routine procedures. This study aims to report a rare case of dual origin and double fenestration of the cephalic vein. Methods: During a cadaveric dissection, a variation of the cephalic vein was identified. Results: In this case, an origin of the cephalic vein was observed arising from the dorsal venous network of the hand. It exhibited a double fenestration in the forearm, where a branch of the medial cutaneous nerve of the forearm perforated it before draining into the brachial vein. The second, a proximal origin, arose from the convergence of two tributaries—one originating from the subcutaneous tissue lateral to the brachial muscle and the other from the biceps brachii muscle, forming a single trunk that drained into the subclavian vein. Conclusions: This rare variation of the cephalic vein (dual origin and fenestration) carries significant hemodynamic implications, including an increased risk of turbulence and thrombosis. The atypical anatomical relationship between the nerve and the fenestrated vein also heightens the potential for iatrogenic injuries. In-depth knowledge of such anomalies is crucial for healthcare professionals to minimize complications and optimize the success of procedures like venous access and arteriovenous fistulas, ultimately ensuring patient safety. Full article

Background: Larger brains are believed to rely more heavily on intra-hemispheric than inter-hemispheric processing, which may lead to a proportionally reduced callosal size. Methods: To test this hypothesis, we used T1-weighted magnetic resonance images from a large population sample (n = 38,034). The sample was drawn from the UK Biobank and included 19,947 females and 18,087 males, aged between 44 and 83 years (mean ± SD: 64 ± 7.72 years). Linear modelling was used to assess the relationship between proportional callosal volume and total intracranial volume, with sex, age, and handedness included as covariates and interaction terms. Results: We observed a significant negative relationship between proportional callosal volume and total brain volume, such that larger brains had proportionally smaller corpora callosa. Conclusion: These findings support the hypothesis that increasing brain size is associated with reduced inter-hemispheric connectivity, potentially due to conduction constraints that promote greater intra-hemispheric processing in larger brains. Full article