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Organoids, Volume 3, Issue 4

2024 December - 4 articles

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Articles (4)

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Article

1 Citations

2,724 Views

14 Pages

Pre-Adipocytes in 3D Co-Culture Underwent Self-Differentiation: New Perspectives for an Old Model

Tamara Dal-Mora,
Najla Adel Saleh,
Veridiana Pacheco Goulart Martinazzo,
Maria Luiza Carneiro Buchele,
Michele Patrícia Rode,
Adny Henrique Silva,
Laura Sartori Assunção,
Tânia Beatriz Creczynski-Pasa and
Fabiola Branco Filippin-Monteiro

Organoids2024, 3(4), 295-308;https://doi.org/10.3390/organoids3040018

18 December 2024

Adipogenesis is a complex process influenced by various cellular interactions within adipose tissue, which plays a critical role in metabolic homeostasis. This study aimed to develop a novel in vitro three-dimensional (3D) co-culture model using muri...

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Feature Paper
Article

3,972 Views

14 Pages

Establishment and Validation of Patient-Derived Non-Small Cell Lung Cancer Organoids as In Vitro Lung Cancer Models

Raphael S. Werner,
Jae-Hwi Jang,
Markus Rechsteiner,
Michaela B. Kirschner and
Isabelle Opitz

Organoids2024, 3(4), 281-294;https://doi.org/10.3390/organoids3040017

9 November 2024

Background: Recent advances in the personalized treatment of non-small cell lung cancer (NSCLC) require representative in vitro model systems that reflect tumor heterogeneity and maintain the characteristic genetic aberrations. We therefore aimed to...

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Review

1 Citations

4,506 Views

15 Pages

Precision Medicine for Gastric Cancer: Current State of Organoid Drug Testing

Tharindie N. Silva,
Josephine A. Wright,
Daniel L. Worthley and
Susan L. Woods

Organoids2024, 3(4), 266-280;https://doi.org/10.3390/organoids3040016

31 October 2024

Gastric cancer (GC) presents a significant health challenge and ranks as the fifth most common cancer in the world. Unfortunately, most patients with GC exhaust standard care treatment options due to late diagnosis and tumour heterogeneity that leads...

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Review

8 Citations

8,075 Views

19 Pages

Bioengineering Tooth and Periodontal Organoids from Stem and Progenitor Cells

Fuad Gandhi Torizal,
Syarifah Tiara Noorintan and
Zakiya Gania

Organoids2024, 3(4), 247-265;https://doi.org/10.3390/organoids3040015

3 October 2024

Tooth and periodontal organoids from stem and progenitor cells represent a significant advancement in regenerative dentistry, offering solutions for tooth loss and periodontal diseases. These organoids, which mimic the architecture and function of re...

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