Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Case | Sex | Age | Cancer Type | Ongoing Anti-Cancer Treatment | Time from PAC Placement to Bacteremia (Months) | Date of First Positive Blood Culture | Associated Symptoms | MALDI-TOF MS Identification (% Confidence Value) | Antibiotic Treatment | Recurrence of Bacteremia with Use of PAC | Outcomeome |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | F | 50 | Breast cancer | Trastuzumab-paclitaxel | 4 | 14 January 2022: blood drawn from peripheral vein and PAC | Shaking chills, rash, scapular arthralgia for 3 days after infusion | Ralstonia insidiosa (99.9) | Ciprofloxacin; lock-therapy with piperacillin/ tazobactam | Yes | Symptoms: no recurrence after lock therapy; Bacteremia: resolved only after PAC removal |
2 | F | 53 | Breast cancer | Trastuzumab | 12 | 21 January 2022: blood drawn from peripheral vein and PAC | Fever (40 °C), headache, arthralgia only during infusion | Ralstonia insidiosa (99.9) | Levofloxacin | Yes | Symptoms: no recurrence after antibiotic therapy; Bacteremia: resolved only after PAC removal |
3 | F | 54 | Breast cancer | Trastuzumab-paclitaxel | 4 | 15 February 2022: blood drawn from PAC | Fever (38 °C), chills only during infusion | Ralstonia insidiosa (99.9) | Lock-therapy with piperacillin/ tazobactam | No | Symptoms and bacteremia resolved |
4 | F | 53 | Breast cancer | Paclitaxel | 3 | 17 February 2022: blood drawn from peripheral vein and PAC | Fever (38 °C) and shaking chills only during infusion | Ralstonia insidiosa (99.9) | Ciprofloxacin | No | Recovered |
5 | F | 68 | Breast cancer | Trastuzumab-pertuzumab | 46 | 4 March 2022: blood drawn from peripheral vein and PAC | Shaking chills and malaise on the day of infusion | Ralstonia insidiosa (99.9) | Lock-therapy with piperacillin/ tazobactam | No | Recovered |
6 | F | 68 | Breast cancer | Trastuzumab-pertuzumab | 21 | 9 March 2022: blood drawn from PAC | Shaking chills and malaise on the day of infusion | Ralstonia insidiosa (99.9) | Lock-therapy with piperacillin/ tazobactam | No | Recovered |
7 | M | 76 | Urothelial carcinoma | Pembrolizumab | 30 | 9 March 2022 Blood drawn from PAC | Shaking chills and malaise only during infusion | Ralstonia insidiosa (99.9) | Lock-therapy with piperacillin/ tazobactam | No | Recovered |
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Ruggieri, L.; Ridolfo, A.L.; Rimoldi, S.G.; Cona, M.S.; Dalu, D.; Olivieri, P.; Rizzardini, G.; Antinori, S.; Gambaro, A.; Ferrario, S.; et al. Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter. Hygiene 2024, 4, 157-163. https://doi.org/10.3390/hygiene4020012
Ruggieri L, Ridolfo AL, Rimoldi SG, Cona MS, Dalu D, Olivieri P, Rizzardini G, Antinori S, Gambaro A, Ferrario S, et al. Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter. Hygiene. 2024; 4(2):157-163. https://doi.org/10.3390/hygiene4020012
Chicago/Turabian StyleRuggieri, Lorenzo, Anna Lisa Ridolfo, Sara Giordana Rimoldi, Maria Silvia Cona, Davide Dalu, Pietro Olivieri, Giuliano Rizzardini, Spinello Antinori, Anna Gambaro, Sabrina Ferrario, and et al. 2024. "Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter" Hygiene 4, no. 2: 157-163. https://doi.org/10.3390/hygiene4020012
APA StyleRuggieri, L., Ridolfo, A. L., Rimoldi, S. G., Cona, M. S., Dalu, D., Olivieri, P., Rizzardini, G., Antinori, S., Gambaro, A., Ferrario, S., Fasola, C., Antista, M., Rea, C. G., & La Verde, N. (2024). Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter. Hygiene, 4(2), 157-163. https://doi.org/10.3390/hygiene4020012