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J. Ageing Longev., Volume 4, Issue 1 (March 2024) – 3 articles

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13 pages, 412 KiB  
Protocol
The Effectiveness and Cost-Effectiveness of the ‘Walk with Me’ Peer-Led Walking Intervention to Increase Physical Activity in Inactive Older Adults: Study Protocol for a Randomised Controlled Trial
by Conor Cunningham, Maeve O’Doherty, Ruth D. Neill, Michael Adams, Frank Kee, Margaret E. Cupples, Wendy Hardeman, Ellen Elizabeth Anne Simpson, Marie H. Murphy, Chris Callaghan, Roger O’Sullivan, Colette Brolly, Ashley Agus, Cliona McDowell, Bob Laventure, Siobhan Casey, Suzanne M. McDonough and Mark A. Tully
J. Ageing Longev. 2024, 4(1), 28-40; https://doi.org/10.3390/jal4010003 - 15 Mar 2024
Viewed by 1856
Abstract
Background: The proportion of the population aged 65 years or older is increasing. Typically, physical activity and health decline with age, which is why action to promote active ageing is a major public health priority, particularly due to health inequalities in older adults. [...] Read more.
Background: The proportion of the population aged 65 years or older is increasing. Typically, physical activity and health decline with age, which is why action to promote active ageing is a major public health priority, particularly due to health inequalities in older adults. The aim of this study is to assess the effectiveness and cost-effectiveness of the Walk with Me peer-led walking intervention for older adults. Methods: This study is a two-arm, assessor-blind, randomised controlled trial. The intervention is a 12-week peer-led walking intervention based on social cognitive theory. Participants in the control group will receive information on active ageing and healthy nutrition. The study will target 348 community-dwelling older adults, aged 60 years or over living in areas of socio-economic disadvantage communities. Trained peer mentors will deliver the intervention. The primary outcome will be a mean between-group change in moderate-to-vigorous physical activity at 12 months from baseline, measured using an Actigraph accelerometer. Secondary outcomes will include quality of life, mental wellbeing, blood pressure, BMI and waist circumference. An embedded process evaluation will involve focus groups and participant diaries. Discussion: Evidence-based, cost-effective interventions to promote physical activity in older adults living in socio-economically disadvantaged communities are needed to address health inequalities. Full article
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13 pages, 1581 KiB  
Article
Early Exposure to Polyphenol-Rich Sugarcane Extract (PRSE) Mitigates Aging While Enhancing Thermotolerance in C. elegans
by Deniz Heydarian, Matthew Flavel, Mihiri Munasinghe, Abdullah Almotayri, Markandeya Jois and Jency Thomas
J. Ageing Longev. 2024, 4(1), 15-27; https://doi.org/10.3390/jal4010002 - 26 Feb 2024
Viewed by 1464
Abstract
Previous research has established that polyphenols increase lifespan and stress resistance in C. elegans. However, the effects of timing of exposure on the extension of lifespan and the mechanisms involved are not completely understood. This study aims to clarify the influence of [...] Read more.
Previous research has established that polyphenols increase lifespan and stress resistance in C. elegans. However, the effects of timing of exposure on the extension of lifespan and the mechanisms involved are not completely understood. This study aims to clarify the influence of the timing of polyphenol-rich sugarcane extract (PRSE) administration on the lifespan of Caenorhabditis elegans. C. elegans worms were subjected to a diet containing PRSE powder at various larval stages until their death. The optimal concentration for lifespan extension was found to be 5 mg/mL PRSE, which increased the lifespan of N2 worms by 18.12% compared to the control group. Mutant strains were also tested, and worm thermotolerance assays were used to assess age-related health at different life stages. Lifespan was notably extended when PRSE was introduced at the first larval stage and 15 h thereafter. No significant extension of lifespan was observed when introduced later in life. The lifespan of DAF-16 and DAF-2 mutants remained unaffected by PRSE. Improved thermotolerance was observed, especially in young and middle-aged worms. Early initiation and sustained intake of PRSE might improve the heat stress and lifespan, implicating the insulin/IGF-1 signaling pathway as a likely mediator in C. elegans. Full article
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14 pages, 414 KiB  
Article
Health and Benefits of Dog Companionship in Women over 50 Years Old
by Heidi A. Kluess and Rebecca L. Jones
J. Ageing Longev. 2024, 4(1), 1-14; https://doi.org/10.3390/jal4010001 - 25 Jan 2024
Cited by 1 | Viewed by 1840
Abstract
Background: The purpose of this study was to investigate the health and wellness benefits of dog companionship in a population of women over 50 years old. Methods: This study used a combination of an online survey (n = 284 self-identified dog companions, n [...] Read more.
Background: The purpose of this study was to investigate the health and wellness benefits of dog companionship in a population of women over 50 years old. Methods: This study used a combination of an online survey (n = 284 self-identified dog companions, n = 71 non-dog companions) and in-person fitness testing (n = 24 dog companions and n = 7 non-dog companions). In-person testing included the 6 min walk, handgrip strength, and chair stand tests. Results: From the questionnaire: Dog companions were 61 ± 7 years old and non-dog companions were 58 ± 6 years old. Dog companions reported 3 ± 2 medical diagnoses and 2 ± 1 medications, but non-dog companions only reported 2 ± 1 medical diagnoses and 1 ± 1 medications (p < 0.001). Satisfaction with life scores and interpersonal communication competence scores were higher for dog companions compared to non-dog companions (p < 0.001). Dog companions and non-dog companions reported similar amounts of time per week on vigorous activity. However, the number of days per week in which dog companions participated in moderate activity was higher than in non-dog companions (p < 0.05). Dog companions also reported walking more days per week and for a longer time than non-dog companions (p < 0.05). There were no differences in the in-person testing (6 min walk, handgrip strength, chair stand tests) between groups. Conclusions: When the in-person testing scores were compared to national standards, the women in this study were average to above average. Overall, women over 50 that own dogs walk more and have better life satisfaction, compared to non-dog companions. Full article
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