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Case Report

Reconstruction of a Thrombosed Aneurysmal Radio-Cephalic Arteriovenous Fistula with a Tubular Bovine Pericardial Conduit

by
Alexandru-Andrei Ujlaki-Nagi
1,†,
Ludovic-Alexandru Szanto
2,†,
Elena Florea
2,*,
Nicolae-Alexandru Lazar
2,
Suzana-Vasilica Șincaru
2,
Adrian Vasile Mureșan
3,
Eliza Russu
3,
Réka Bartus
3,
Eliza-Mihaela Arbănași
4,5,
Ioan Hosu
6,
Marius Mihai Harpa
5,7,
Claudiu Constantin Ciucanu
3,4 and
Emil-Marian Arbănași
3,4,5
1
Psychiatry Clinic 2, Mures County Clinical Hospital, 540139 Targu Mures, Romania
2
Clinic of Vascular Surgery, Mures County Emergency Hospital, 540136 Targu Mures, Romania
3
Department of Vascular Surgery, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania
4
Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania
5
Regenerative Medicine Laboratory, Centre for Advanced Medical and Pharmaceutical Research (CCAMF), George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania
6
Department of Nephrology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540139 Targu Mures, Romania
7
Department of Surgery IV, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures, 540142 Targu Mures, Romania
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Kidney Dial. 2025, 5(3), 46; https://doi.org/10.3390/kidneydial5030046
Submission received: 23 July 2025 / Revised: 31 August 2025 / Accepted: 11 September 2025 / Published: 13 September 2025

Abstract

We report the case of a 44-year-old man with end-stage kidney disease (ESKD) who has been on chronic hemodialysis via a radio-cephalic arteriovenous fistula (RC-AVF) for one year. The patient arrived at the emergency department due to an inability to continue dialysis through the AVF. Clinical and ultrasound exams reveal an aneurysm in the cephalic vein, measuring 2.3 cm (cm) in diameter and 5 cm long, located in the middle third of the forearm, with intraluminal thrombosis. A surgical procedure is planned to exclude the aneurysmal segment and reconnect the vein, using a graft made from a bovine pericardium patch. Immediately after surgery, a thrill is detectable, and ultrasound shows a flow rate of 651 mL/min. On the second day, dialysis is performed through the distal cephalic vein segment under ultrasound guidance, avoiding the median forearm zone. At one month, the fistula remains functional, with no signs of thrombosis or stenosis. The bovine pericardium tubular graft has shown complete integration. This case supports the feasibility, safety, and potential advantages of using a tubularized bovine pericardial graft as an alternative conduit for RC-AVF reconstruction in select patients. However, further studies on larger cohorts and with extended follow-up are necessary to validate its reproducibility and long-term patency.
Keywords: arteriovenous fistula; RC-AVF; bovine pericardium; aneurysmal RC-AVF; vascular access; open surgery arteriovenous fistula; RC-AVF; bovine pericardium; aneurysmal RC-AVF; vascular access; open surgery

Share and Cite

MDPI and ACS Style

Ujlaki-Nagi, A.-A.; Szanto, L.-A.; Florea, E.; Lazar, N.-A.; Șincaru, S.-V.; Mureșan, A.V.; Russu, E.; Bartus, R.; Arbănași, E.-M.; Hosu, I.; et al. Reconstruction of a Thrombosed Aneurysmal Radio-Cephalic Arteriovenous Fistula with a Tubular Bovine Pericardial Conduit. Kidney Dial. 2025, 5, 46. https://doi.org/10.3390/kidneydial5030046

AMA Style

Ujlaki-Nagi A-A, Szanto L-A, Florea E, Lazar N-A, Șincaru S-V, Mureșan AV, Russu E, Bartus R, Arbănași E-M, Hosu I, et al. Reconstruction of a Thrombosed Aneurysmal Radio-Cephalic Arteriovenous Fistula with a Tubular Bovine Pericardial Conduit. Kidney and Dialysis. 2025; 5(3):46. https://doi.org/10.3390/kidneydial5030046

Chicago/Turabian Style

Ujlaki-Nagi, Alexandru-Andrei, Ludovic-Alexandru Szanto, Elena Florea, Nicolae-Alexandru Lazar, Suzana-Vasilica Șincaru, Adrian Vasile Mureșan, Eliza Russu, Réka Bartus, Eliza-Mihaela Arbănași, Ioan Hosu, and et al. 2025. "Reconstruction of a Thrombosed Aneurysmal Radio-Cephalic Arteriovenous Fistula with a Tubular Bovine Pericardial Conduit" Kidney and Dialysis 5, no. 3: 46. https://doi.org/10.3390/kidneydial5030046

APA Style

Ujlaki-Nagi, A.-A., Szanto, L.-A., Florea, E., Lazar, N.-A., Șincaru, S.-V., Mureșan, A. V., Russu, E., Bartus, R., Arbănași, E.-M., Hosu, I., Harpa, M. M., Ciucanu, C. C., & Arbănași, E.-M. (2025). Reconstruction of a Thrombosed Aneurysmal Radio-Cephalic Arteriovenous Fistula with a Tubular Bovine Pericardial Conduit. Kidney and Dialysis, 5(3), 46. https://doi.org/10.3390/kidneydial5030046

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