SARS-CoV-2 Infection Epidemiology Changes During Three Years of Pandemic in a Region in Central India
Abstract
1. Introduction
2. Method
2.1. Study Design, Period, and Settings
2.2. Sample Collection and Processing
2.3. Viral Nucleic Acid Extraction
2.4. Real-Time PCR
2.5. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Year | 2020 | 2021 | 2022 | p-Value |
---|---|---|---|---|
Overall Positivity | 13,035 (13.29) | 42,909 (13.66) | 19,936 (15.91) | <0.001 |
District | <0.001 | |||
Bhandara | 1807 (13.86) | 73 (0.17) | 23 (0.11) | |
Chandrapur | 49 (0.38) | 27 (0.07) | 15 (0.07) | |
Gadchiroli | 304 (2.33) | 11 (0.03) | 4 (0.02) | |
Gondia | 55 (0.42) | 22 (0.05) | 11 (0.06) | |
Nagpur | 10,402 (79.80) | 42,275 (98.52) | 19,791 (99.28) | |
Wardha | 22 (0.16) | 22 (0.05) | 8 (0.04) | |
Other | 396 (3.04) | 479 (1.11) | 84 (0.42) | |
Gender | <0.001 | |||
Male | 7935 (60.88) | 24,811 (57.82) | 11,640 (58.39) | |
Female | 5099 (39.11) | 18,096 (42.17) | 8294 (41.60) | |
Transgender | 1 (0.01) | 2 (0.01) | 2 (0.01) | |
Age Group (years) | <0.001 | |||
1–15 | 918 (7.04) | 3235 (7.54) | 1707 (8.56) | |
16–30 | 3476 (26.66) | 12,121 (28.25) | 6735 (33.80) | |
31–45 | 3876 (29.74) | 14,275 (33.27) | 6192 (31.05) | |
45+ | 4765 (36.56) | 13,278 (30.94) | 5302 (26.59) | |
Vaccination | <0.001 | |||
Yes | 0 | 10,381 (3.30) | 10,105 (8.06) | |
No | 0 | 303,537 (96.69) | 115,237 (91.93) | |
Hospitalization | <0.001 | |||
Yes | 5203 (5.30) | 2903 (0.92) | 266 (0.21) | |
No | 92,857 (94.70) | 311,015 (99.08) | 125,076 (99.79) | |
Clinical Status | <0.001 | |||
Symptomatic | 9264 (9.44) | 7651 (2.43) | 6230 (4.98) | |
Asymptomatic | 88,796 (90.56) | 306,267 (97.57) | 119,112 (95.02) |
Parameter | 2020 | 2021 | 2022 |
---|---|---|---|
Cumulative confirmed cases | 8607 | 6882 | 672 |
Deaths | 1562 | 2525 | 103 |
Case fatality ratio (CFR) | 18.14% | 36.68% | 15.32% |
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Deshmukh, P.; Bhise, S.; Kokate, S.; Mategadikar, P.; Rahangdale, H.; Rahangdale, V.; Shrikhande, S.; Pathan, S.; Damodare, A.; Baghele, S.; et al. SARS-CoV-2 Infection Epidemiology Changes During Three Years of Pandemic in a Region in Central India. COVID 2025, 5, 125. https://doi.org/10.3390/covid5080125
Deshmukh P, Bhise S, Kokate S, Mategadikar P, Rahangdale H, Rahangdale V, Shrikhande S, Pathan S, Damodare A, Baghele S, et al. SARS-CoV-2 Infection Epidemiology Changes During Three Years of Pandemic in a Region in Central India. COVID. 2025; 5(8):125. https://doi.org/10.3390/covid5080125
Chicago/Turabian StyleDeshmukh, Pravin, Swati Bhise, Sandeep Kokate, Priyanka Mategadikar, Hina Rahangdale, Vaishali Rahangdale, Sunanda Shrikhande, Sana Pathan, Anuradha Damodare, Sachin Baghele, and et al. 2025. "SARS-CoV-2 Infection Epidemiology Changes During Three Years of Pandemic in a Region in Central India" COVID 5, no. 8: 125. https://doi.org/10.3390/covid5080125
APA StyleDeshmukh, P., Bhise, S., Kokate, S., Mategadikar, P., Rahangdale, H., Rahangdale, V., Shrikhande, S., Pathan, S., Damodare, A., Baghele, S., Gajbhiye, J., & Shahu, P. (2025). SARS-CoV-2 Infection Epidemiology Changes During Three Years of Pandemic in a Region in Central India. COVID, 5(8), 125. https://doi.org/10.3390/covid5080125