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Review

More than Heat: The Complex Nature of Pungent Capsicum spp.

by
Filomena Monica Vella
1,
Domenico Cautela
2 and
Bruna Laratta
1,*
1
Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), Via P. Castellino 111, 80131 Napoli, NA, Italy
2
Department of Theoretical and Applied Sciences, E-Campus University, Via Isimbardi 10, 22060 Novedrate, CO, Italy
*
Author to whom correspondence should be addressed.
Compounds 2025, 5(4), 61; https://doi.org/10.3390/compounds5040061
Submission received: 20 October 2025 / Revised: 10 December 2025 / Accepted: 16 December 2025 / Published: 18 December 2025
(This article belongs to the Special Issue Compounds–Derived from Nature)

Abstract

For centuries, people have used herbs, plants, and spices as remedies for health problems or simply to ameliorate body energy or vitality because of the bioactive compounds they contain. The Capsicum genus, which includes the chili pepper, is one of the oldest crops to be domesticated and used. It is characterized by three qualities: pungency/flavor, color, and aroma. Capsaicinoids are responsible for the pungent flavor. Carotenoids and flavonoids determine the remarkable and colorful tones of chili peppers. Volatile compounds provide their characteristic aroma. This prompts consumers to purchase and utilize the numerous varieties of chili peppers, whether fresh or dried. The presence of these bioactive compounds gives chili peppers functional attributes that promote health. This paper reviews the scientific research carried out over the last 25 years on these attributes. This paper also looks at how Capsicum fruits could be used as a valuable source of nutrients from plants that have beneficial biological properties.
Keywords: Capsicum spp.; chili pepper; capsaicinoid; carotenoid; flavonoid; volatile compounds; biological activity; alkaloid; ethnopharmacology Capsicum spp.; chili pepper; capsaicinoid; carotenoid; flavonoid; volatile compounds; biological activity; alkaloid; ethnopharmacology

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MDPI and ACS Style

Vella, F.M.; Cautela, D.; Laratta, B. More than Heat: The Complex Nature of Pungent Capsicum spp. Compounds 2025, 5, 61. https://doi.org/10.3390/compounds5040061

AMA Style

Vella FM, Cautela D, Laratta B. More than Heat: The Complex Nature of Pungent Capsicum spp. Compounds. 2025; 5(4):61. https://doi.org/10.3390/compounds5040061

Chicago/Turabian Style

Vella, Filomena Monica, Domenico Cautela, and Bruna Laratta. 2025. "More than Heat: The Complex Nature of Pungent Capsicum spp." Compounds 5, no. 4: 61. https://doi.org/10.3390/compounds5040061

APA Style

Vella, F. M., Cautela, D., & Laratta, B. (2025). More than Heat: The Complex Nature of Pungent Capsicum spp. Compounds, 5(4), 61. https://doi.org/10.3390/compounds5040061

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