Extending the Reach of Interventions to Treat Mental Disorders
Abstract
1. Introduction
2. Background: The Mental Health Treatment Gap
3. Scope of Mental Health Problems
4. Treatment Delivery to Those in Need
5. General Comments
- Mental health problems, including psychiatric disorders, subclinical disorders, and other problems (loneliness, social isolation), are pervasive. The psychiatric disorders alone affect 50% of the population over the course of their lives.
- The problems are on the rise for children, adolescents, adults, and older individuals. This does not appear to be due to better assessment or diagnoses, but genuine increases in impairments.
- The majority of individuals with mental health problems do not receive treatment, and that applies to individuals in countries spanning all economic levels.
- When people do receive treatment, it is rarely an intervention that is evidence-based. Clearly, a priority is not only to ensure that more people in need receive services, but when they do, that they receive those that are evidence-based.
6. Why People in Need Do Not Receive Services
7. Interventions: Beyond Traditional Mental Health Services
- Treatment sessions are provided in person and one-to-one with a client (individual, couple, or family);
- Treatment is administered by a highly trained (e.g., master’s or doctoral level) mental health professional (e.g., psychologist, psychiatrist, social worker, family therapist);
- Sessions are held at a clinic, private office, or health-care facility.
8. Digital and Technology-Based Interventions
9. General Comments
10. Everyday Life Activities
11. Limitations and Qualifications
12. Conclusions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Insel, T.R. Healing: Our Path from Mental Illness to Mental Health; Penguin Books: New York, NY, USA, 2022. [Google Scholar]
- Kohn, R.; Saxena, S.; Levav, I.; Saraceno, B. The treatment gap in mental health care. Bull. World Health Organ. 2004, 82, 858–866. [Google Scholar]
- Patel, V.; Weiss, H.A.; Chowdhary, N.; Naik, S.; Pednekar, S.; Chatterjee, S.; De Silva, M.J.; Bhat, B.; Araya, R.; King, M.; et al. Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): A cluster randomised controlled trial. Lancet 2010, 376, 2086–2095. [Google Scholar] [CrossRef] [PubMed]
- Andrade, C.; Radhakrishnan, R. Prayer and healing: A medical and scientific perspective on randomized controlled trials. Indian J. Psychiatry 2009, 51, 247–253. [Google Scholar] [CrossRef] [PubMed]
- Kessler, R.C.; Kazdin, A.E.; Aguilar-Gaxiola, S.; Al-Hamzawi, A.; Alonso, J.; Altwaijr, Y.A.; Andrade, L.H.; Benjet, C.; Bharat, C.; Borges, G.; et al. Patterns and correlates of patient-reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys. World Psychiatry 2022, 21, 272–286. [Google Scholar] [CrossRef] [PubMed]
- Steel, Z.; Marnane, C.; Iranpour, C.; Chey, T.; Jackson, J.W.; Patel, V.; Silove, D. The global prevalence of common mental disorders: A systematic review and meta-analysis 1980–2013. Int. J. Epidemiol. 2014, 43, 476–493. [Google Scholar] [CrossRef]
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th ed.; Text Revised; American Psychiatric Association: Washington, DC, USA, 2022. [Google Scholar]
- World Health Organization. International Statistical Classification of Diseases and Related Health Problems (ICD-11); WHO: Geneva, Switzerland, 2019. [Google Scholar]
- McGrath, J.J.; Al-Hamzawi, A.; Alonso, J.; Altwaijri, Y.; Andrade, L.H.; Bromet, E.J.; Bruffaerts, R.; de Almeida, J.M.C.; Chardoul, S.; Chiu, W.T.; et al. Age of onset and cumulative risk of mental disorders: A cross-national analysis of population surveys from 29 countries. Lancet Psychiatry 2023, 10, 668–681. [Google Scholar] [CrossRef]
- Lebrun-Harris, L.A.; Ghandour, R.M.; Kogan, M.D.; Warren, M.D. Five-year trends in US children’s health and well-being, 2016–2020. JAMA Pediatr. 2022, 176, e220056. [Google Scholar] [CrossRef]
- Patalay, P.; Gage, S.H. Changes in millennial adolescent mental health and health-related behaviours over 10 years: A population cohort comparison study. Int. J. Epidemiol. 2019, 48, 1650–1664. [Google Scholar] [CrossRef]
- Johnson, J.; Byrne, G.J.; Pelecanos, A.M. The prevalence of subthreshold psychiatric symptoms and associations with alcohol and substance use disorders: From a nationally representative survey of 36,309 adults. BMC Psychiatry 2022, 22, 270. [Google Scholar] [CrossRef]
- Mushtaq, M.; Sultana, S.; Imtiaz, I. The trauma of sexual harassment and its mental health consequences among nurses. J. Coll. Physicians Surg. Pak. 2015, 25, 675–679. [Google Scholar]
- Victor, C.R.; Yang, K. The prevalence of loneliness among adults: A case study of the United Kingdom. J. Psychol. 2012, 146, 85–104. [Google Scholar] [CrossRef]
- World Health Organization. WHO Commission on Social Connection; WHO: Geneva, Switzerland, 2024; Available online: https://www.who.int/groups/commission-on-social-connection (accessed on 3 March 2026).
- Hull, M. Poor Mental Health’s Devastating Impacts on Life Expectancy—And How Treatment Can Help. The Recovery Village. 2022. Available online: https://www.therecoveryvillage.com/mental-health/ (accessed on 3 March 2026).
- Plana-Ripoll, O.; Musliner, K.L.; Dalsgaard, S.; Momen, N.C.; Weye, N.; Christensen, M.K.; Agerbo, E.; Iburg, K.M.; Laursen, T.M.; Mortensen, P.B.; et al. Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study. World Psychiatry 2020, 19, 339–349. [Google Scholar] [CrossRef]
- Meier, S.M.; Mattheisen, M.; Mors, O.; Mortensen, P.B.; Laursen, T.M.; Penninx, B.W. Increased mortality among people with anxiety disorders: Total population study. Br. J. Psychiatry 2016, 209, 216–221. [Google Scholar] [CrossRef]
- Barnes, T.L.; Ahuja, M.; MacLeod, S.; Tkatch, R.; Albright, L.; Schaeffer, J.A.; Yeh, C.S. Loneliness, social isolation, and all-cause mortality in a large sample of older adults. J. Aging Health 2022, 34, 883–892. [Google Scholar] [CrossRef] [PubMed]
- Arias, D.; Saxena, S.; Verguet, S. Quantifying the global burden of mental disorders and their economic value. EClinicalMedicine 2022, 54, 101675. [Google Scholar] [CrossRef] [PubMed]
- Vigo, D.V.; Jones, L.; Atun, R.; Thornicroft, G. The true global disease burden of mental illness: Still elusive. Lancet Psychiatry 2022, 9, 98–100. [Google Scholar] [CrossRef] [PubMed]
- Evans-Lacko, S.A.G.S.; Aguilar-Gaxiola, S.; Al-Hamzawi, A.; Alonso, J.; Benjet, C.; Bruffaerts, R.; Chiu, W.T.; Florescu, S.; de Girolamo, G.; Gureje, O.; et al. Socio-economic variations in the mental health treatment gap for people with anxiety, mood, and substance use disorders: Results from the WHO World Mental Health (WMH) surveys. Psychol. Med. 2018, 48, 1560–1571. [Google Scholar] [CrossRef]
- Thornicroft, G.; Chatterji, S.; Evans-Lacko, S.; Gruber, M.; Sampson, N.; Aguilar-Gaxiola, S.; Al-Hamzawi, A.; Alonso, J.; Andrade, L.; Borges, G.; et al. Undertreatment of people with major depressive disorder in 21 countries. Br. J. Psychiatry 2017, 210, 119–124. [Google Scholar] [CrossRef]
- Grant, B.F.; Goldstein, R.B.; Saha, T.D.; Chou, S.P.; Jung, J.; Zhang, H.; Pickering, R.P.; Ruan, W.J.; Smith, S.M.; Huang, B.; et al. Epidemiology of DSM-5 alcohol use disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry 2015, 72, 757–766. [Google Scholar] [CrossRef]
- Lora, A.; Kohn, R.; Levav, I.; McBain, R.; Morris, J.; Saxena, S. Service availability and utilization and treatment gap for schizophrenic disorders: A survey in 50 low-and middle-income countries. Bull. World Health Organ. 2012, 90, 47–54B. [Google Scholar] [CrossRef]
- Veron, L.; Sauvade, F.; Le Barbenchon, E. Why do students in psychological distress not use psychological care? Psychol. Serv. 2020, 19, 85–94. [Google Scholar] [CrossRef] [PubMed]
- Correll, C.U.; Cortese, S.; Croatto, G.; Monaco, F.; Krinitski, D.; Arrondo, G.; Ostinelli, E.G.; Zangani, C.; Fornaro, M.; Estradé, A.; et al. Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: An umbrella review. World Psychiatry 2021, 20, 244–275. [Google Scholar] [CrossRef] [PubMed]
- Cuijpers, P.; Harrer, M.; Miguel, C.; Ciharova, M.; Papola, D.; Basic, D.; Botella, C.; Cristea, I.; de Ponti, N.; Donker, T.; et al. Cognitive behavior therapy for mental disorders in adults: A unified series of meta-analyses. JAMA Psychiatry 2025, 82, 563–571. [Google Scholar] [CrossRef] [PubMed]
- Fordham, B.; Sugavanam, T.; Edwards, K.; Stallard, P.; Howard, R.; Das Nair, R.; Copsey, B.; Lee, H.; Howick, J.; Hemming, K.; et al. The evidence for cognitive behavioural therapy in any condition, population or context: A meta-review of systematic reviews and panoramic meta-analysis. Psychol. Med. 2021, 51, 21–29. [Google Scholar] [CrossRef]
- Vigo, D.V.; Stein, D.J.; Harris, M.G.; Kazdin, A.E.; Viana, M.C.; Munthali, R.; Munro, L.; Hwang, I.; Kessler, T.L.; Manoukian, S.M.; et al. Effective treatment for mental and substance use disorders in 21 countries. JAMA Psychiatry 2025, 82, 347–357. [Google Scholar] [CrossRef]
- Franca, M.H.; Wang, Y.P.; Andrade, L.H.; Viana, M.C. Treatment gap of mental disorders in São Paulo Metropolitan Area, Brazil: Failure and delay in initiating treatment contact after first onset of mental and substance use disorders. Int. J. Ment. Health Addict. 2023, 21, 3659–3677. [Google Scholar] [CrossRef]
- Stein, D.J.; Kazdin, A.E.; Munthali, R.J.; Hwang, I.; Harris, M.G.; Alonso, J.; Andrade, L.H.; Bruffaerts, R.; Cardoso, G.; Chardoul, S.; et al. Determinants of effective treatment coverage for posttraumatic stress disorder: Findings from the World Mental Health Surveys. BMC Psychiatry 2023, 23, 226. [Google Scholar] [CrossRef]
- Byrow, Y.; Pajak, R.; Specker, P.; Nickerson, A. Perceptions of mental health and perceived barriers to mental health help-seeking amongst refugees: A systematic review. Clin. Psychol. Rev. 2020, 75, 101812. [Google Scholar] [CrossRef]
- Goodcase, E.T.; Brewe, A.M.; White, S.W.; Jones, S. Providers as stakeholders in addressing implementation barriers to youth mental healthcare. Community Ment. Health J. 2022, 58, 967–981. [Google Scholar] [CrossRef]
- Pei, J.; Amanvermez, Y.; Vigo, D.; Puyat, J.; Kessler, R.C.; Mortier, P.; Bruffaerts, R.; Rankin, O.; Chua, S.N.; Martínez, V.; et al. Sociodemographic correlates of mental health treatment seeking among college students: A systematic review and meta-analysis. Psychiatr. Serv. 2024, 75, 556–569. [Google Scholar] [CrossRef]
- Reinert, M.; Fritze, D.; Nguyen, T. The State of Mental Health in America 2024; Mental Health America: Alexandra, VA, USA, 2024.
- Viana, M.C.; Kazdin, A.E.; Harris, M.G.; Stein, D.J.; Vigo, D.K.; Hwang, I.; Manoukian, S.M.; Sampson, N.A.; Alonso, J.; Andrade, L.H.; et al. Barriers to 12-month treatment of common anxiety, mood, and substance use disorders in the World Mental Health (WMH) surveys. Int. J. Ment. Health Syst. 2025, 19, 6. [Google Scholar] [CrossRef] [PubMed]
- Hampton, M.; Lenhart, O. Access to health care and mental health—Evidence from the ACA preexisting conditions provision. Health Econ. 2022, 31, 760–783. [Google Scholar] [CrossRef] [PubMed]
- Corrigan, P.W. Lessons learned from unintended consequences about erasing the stigma of mental illness. World Psychiatry 2016, 15, 67–73. [Google Scholar] [CrossRef] [PubMed]
- Dubreucq, J.; Plasse, J.; Franck, N. Self-stigma in serious mental illness: A systematic review of frequency, correlates, and consequences. Schizophr. Bull. 2021, 47, 1261–1287. [Google Scholar] [CrossRef]
- Hajizadeh, A.; Amini, H.; Heydari, M.; Rajabi, F. How to combat stigma surrounding mental health disorders: A scoping review of the experiences of different stakeholders. BMC Psychiatry 2024, 24, 782. [Google Scholar] [CrossRef]
- Mackenzie, C.S.; Heath, P.J.; Vogel, D.L.; Chekay, R. Age differences in public stigma, self-stigma, and attitudes toward seeking help: A moderated mediation model. J. Clin. Psychol. 2019, 75, 2259–2272. [Google Scholar] [CrossRef]
- Maeshima, L.S.; Parent, M.C. Mental health stigma and professional help-seeking behaviors among Asian American and Asian international students. J. Am. Coll. Health 2022, 70, 1761–1767. [Google Scholar] [CrossRef]
- Health Resources and Services Administration. Health Professional Shortage Areas: Mental Health Designated Populations. Rural Assistance Center. 2010. Available online: https://data.hrsa.gov/topics/health-workforce/shortage-areas (accessed on 3 March 2026).
- Keeley, B. The State of the World’s Children 2021: On My Mind—Promoting, Protecting and Caring for Children’s Mental Health; UNICEF: New York, NY, USA, 2021; p. 10017. [Google Scholar]
- Phillips, L.; Cordray, J.; Mendoza, K.; Dorn-Medeiros, C. A closer look at the mental health provider shortage. Couns. Today 2023, 65, 25–39. [Google Scholar]
- Becker, A.E.; Kleinman, A. Mental health and the global agenda. N. Engl. J. Med. 2013, 369, 66–73. [Google Scholar] [CrossRef]
- Crowley, R.A.; Kirschner, N. The integration of care for mental health, substance abuse, and other behavioral health conditions into primary care: Executive summary of an American College of Physicians position paper. Ann. Intern. Med. 2015, 163, 298–299. [Google Scholar] [CrossRef]
- Kazak, A.E.; Nash, J.M.; Hiroto, K.; Kaslow, N.J. Psychologists in patient-centered medical homes (PCMHs): Roles, evidence, opportunities, and challenges. Am. Psychol. 2017, 72, 1–12. [Google Scholar] [CrossRef]
- Xie, M.; Wodzinski, M.; Gajaria, A.; Battaglia, M.; Rotem, A. Impact of urgent youth outpatient mental health care on patient and health system outcomes–a scoping review. Child Adolesc. Ment. Health 2023, 28, 287–298. [Google Scholar] [CrossRef]
- Ansong-DePass, L. A cut above the rest: A qualitative study to evaluate the feasibility of implementing early childhood mental health interventions into Boston Black/African American barbershops and beauty salons. J. Health Disparities Res. Pract. 2022, 15, 4. [Google Scholar]
- Carlton, L.; Woods-Giscombe, C.L.; Palmer, C.; Rodgers, S.G. Barbers as community mental health advocates for African American men: ADAAM-QR web design to address social determinants of depression and access to culturally-relevant resources. Arch. Psychiatr. Nurs. 2021, 35, 137–140. [Google Scholar] [CrossRef] [PubMed]
- Connolly, S.M.; Vanchu-Orosco, M.; Warner, J.; Seidi, P.A.; Edwards, J.; Boath, E.; Irgens, A.C. Mental health interventions by lay counsellors: A systematic review and meta-analysis. Bull. World Health Organ. 2021, 99, 572. [Google Scholar] [CrossRef] [PubMed]
- Schleider, J.L.; Zapata, J.P.; Rapoport, A.; Wescott, A.; Ghosh, A.; Kaveladze, B.; Szkody, E.; Ahuvia, I.L. Single-session interventions for mental health problems and service engagement: Umbrella review of systematic reviews and meta-analyses. Annu. Rev. Clin. Psychol. 2025, 21, 279–303. [Google Scholar] [CrossRef]
- HelpGuide.Org. Mental Health Helplines. 2023. Available online: https://www.helpguide.org/find-help.htm (accessed on 3 March 2026).
- Psycom. Get Help Now—Emergency Mental Health Resources. 2022. Available online: https://www.psycom.net/get-help-mental-health (accessed on 3 March 2026).
- Lattie, E.G.; Stiles-Shields, C.; Graham, A.K. An overview of and recommendations for more accessible digital mental health services. Nat. Rev. Psychol. 2022, 1, 87–100. [Google Scholar] [CrossRef]
- Magnavita, J.J. (Ed.) Using Technology in Mental Health Practice; American Psychological Association: Washington, DC, USA, 2018. [Google Scholar]
- Tal, A.; Torous, J. The digital mental health revolution: Opportunities and risks. Psychiatr. Rehabil. J. 2017, 40, 263–265. [Google Scholar] [CrossRef]
- Kazdin, A.E. Mental Health Interventions in Everyday Life: Beyond Psychotherapy to Reduce Symptoms of Mental Disorders and Improve Mental Health; Oxford University Press: New York, NY, USA, 2025. [Google Scholar]
- Dreyer, F. Examining Beating the Blues, Comprising of: ‘The Effectiveness and Acceptability of Beating the Blues Computerised Cognitive Behaviour Therapy Programme: A Systematic Review’; and, ‘Beating the Blues: Engagement, Attrition and Clinical Outcomes of a Computerised Cognitive Behaviour Therapy Programme and the Impact of COVID-19’. 2022. Available online: https://era.ed.ac.uk/bitstream/handle/1842/39637/Dreyer2022.pdf?sequence=1 (accessed on 3 March 2026).
- Richards, D.; Richardson, T. Computer-based psychological treatments for depression: A systematic review and meta-analysis. Clin. Psychol. Rev. 2012, 32, 329–342. [Google Scholar] [CrossRef]
- Hollis, C.; Falconer, C.J.; Martin, J.L.; Whittington, C.; Stockton, S.; Glazebrook, C.; Davies, E.B. Annual research review: Digital health interventions for children and young people with mental health problems–A systematic and meta-review. J. Child Psychol. Psychiatry 2017, 58, 474–503. [Google Scholar] [CrossRef]
- Rigabert, A.; Motrico, E.; Moreno-Peral, P.; Resurrección, D.M.; Conejo-Cerón, S.; Cuijpers, P.; Martín-Gómez, C.; López-Del-Hoyo, Y.; Bellón, J.Á. Effectiveness of online psychological and psychoeducational interventions to prevent depression: Systematic review and meta-analysis of randomized controlled trials. Clin. Psychol. Rev. 2020, 82, 101931. [Google Scholar] [CrossRef]
- Sander, L.; Rausch, L.; Baumeister, H. Effectiveness of internet-based interventions for the prevention of mental disorders: A systematic review and meta-analysis. JMIR Ment. Health 2016, 3, e6061. [Google Scholar] [CrossRef]
- Titov, N.; Dear, B.F.; Nielssen, O.; Wootton, B.; Kayrouz, R.; Karin, E.; Genest, B.; Bennett-Levy, J.; Purtell, C.; Bezuidenhout, G.; et al. User characteristics and outcomes from a national digital mental health service: An observational study of registrants of the Australian MindSpot Clinic. Lancet Digit. Health 2020, 2, e582–e593. [Google Scholar] [CrossRef] [PubMed]
- Titov, N.; Schofield, C.; Staples, L.; Dear, B.F.; Nielssen, O. A comparison of Indigenous and non-Indigenous users of MindSpot: An Australian digital mental health service. Australas. Psychiatry 2019, 27, 352–357. [Google Scholar] [CrossRef] [PubMed]
- Staples, L.G.; Webb, N.; Asrianti, L.; Cross, S.; Rock, D.; Kayrouz, R.; Karin, E.; Dear, B.F.; Nielssen, O.; Titov, N. A comparison of self-referral and referral via primary care providers, through two similar digital mental health services in Western Australia. Int. J. Environ. Res. Public Health 2022, 19, 905. [Google Scholar] [CrossRef] [PubMed]
- Kessler, R.C.; Amminger, G.P.; Aguilar-Gaxiola, S.; Alonso, J.; Lee, S.; Üstün, T.B. Age of onset of mental disorders: A review of recent literature. Curr. Opin. Psychiatry 2007, 20, 359–364. [Google Scholar] [CrossRef]
- Abd-Alrazaq, A.; Alajlani, M.; Alhuwail, D.; Schneider, J.; Akhu-Zaheya, L.; Ahmed, A.; Househ, M. The effectiveness of serious games in alleviating anxiety: Systematic review and meta-analysis. JMIR Serious Games 2022, 10, e29137. [Google Scholar] [CrossRef]
- Dewhirst, A.; Laugharne, R.; Shankar, R. Therapeutic use of serious games in mental health: Scoping review. BJPsychiatry Open 2022, 8, e37. [Google Scholar] [CrossRef]
- Rabbitt, S.M.; Kazdin, A.E.; Scassellati, B. Integrating socially assistive robotics into mental healthcare interventions: Applications and recommendations for expanded use. Clin. Psychol. Rev. 2015, 35, 35–46. [Google Scholar] [CrossRef]
- Yu, C.; Sommerlad, A.; Sakure, L.; Livingston, G. Socially assistive robots for people with dementia: Systematic review and meta-analysis of feasibility, acceptability and the effect on cognition, neuropsychiatric symptoms and quality of life. Ageing Res. Rev. 2022, 78, 101633. [Google Scholar] [CrossRef]
- Araujo, B.S.D.; Fantinato, M.; Marques Peres, S.; Melo, R.C.D.; Batistoni, S.S.T.; Cachioni, M.; Hung, P.C. Effects of social robots on depressive symptoms in older adults: A scoping review. Libr. Hi Tech 2022, 40, 1108–1126. [Google Scholar] [CrossRef]
- Cano, S.; González, C.S.; Gil-Iranzo, R.M.; Albiol-Pérez, S. Affective communication for socially assistive robots (SARS) for children with autism spectrum disorder: A systematic review. Sensors 2021, 21, 5166. [Google Scholar] [CrossRef] [PubMed]
- Hsieh, C.J.; Li, P.S.; Wang, C.H.; Lin, S.L.; Hsu, T.C.; Tsai, C.M.T. Socially assistive robots for people living with dementia in long-term facilities: A systematic review and meta-analysis of randomized controlled trials. Gerontology 2023, 69, 1027–1042. [Google Scholar] [CrossRef] [PubMed]
- Nichol, B.; McCready, J.; Erfani, G.; Comparcini, D.; Simonetti, V.; Cicolini, G.; Mikkonen, K.; Yamakawa, M.; Tomietto, M. Exploring the impact of socially assistive robots on health and wellbeing across the lifespan: An umbrella review and meta-analysis. Int. J. Nurs. Stud. 2024, 153, 104730. [Google Scholar] [CrossRef]
- Shibata, T.; Wada, K. Robot therapy: A new approach for mental healthcare of the elderly–A mini-review. Gerontology 2011, 57, 378–386. [Google Scholar] [CrossRef]
- Hung, L.; Liu, C.; Woldum, E.; Au-Yeung, A.; Berndt, A.; Wallsworth, C.; Horne, N.; Gregorio, M.; Mann, J.; Chaudhury, H. The benefits of and barriers to using a social robot PARO in care settings: A scoping review. BMC Geriatr. 2019, 19, 232. [Google Scholar] [CrossRef]
- Rashid, N.L.A.; Leow, Y.; Klainin-Yobas, P.; Itoh, S.; Wu, V.X. The effectiveness of a therapeutic robot, ‘Paro’, on behavioural and psychological symptoms, medication use, total sleep time and sociability in older adults with dementia: A systematic review and meta-analysis. Int. J. Nurs. Stud. 2023, 145, 104530. [Google Scholar] [CrossRef]
- Wang, X.; Shen, J.; Chen, Q. How PARO can help older people in elderly care facilities: A systematic review of RCT. Int. J. Nurs. Knowl. 2022, 33, 29–39. [Google Scholar] [CrossRef]
- Leonardsen, A.C.L.; Hardeland, C.; Helgesen, A.K.; Bååth, C.; Del Busso, L.; Grøndahl, V.A. The use of robotic technology in the healthcare of people above the age of 65—A systematic review. Healthcare 2023, 11, 904. [Google Scholar] [CrossRef]
- Pew Research Center. The Global Religious Landscape. 2012. Available online: https://www.pewresearch.org/religion/2012/12/18/global-religious-landscape-exec/#:~:text=A%20comprehensive%20demographic%20study%20of,world%20population%20of%206.9%20billion (accessed on 3 March 2026).
- Center for Disease Control and Prevention. Benefits of Physical Activity. Division of Nutrition, Physical Activity, and Obesity, National Center for Chronic Disease Prevention and Health Promotion. 2021. Available online: https://www.cdc.gov/physical-activity-basics/benefits/?CDC_AAref_Val=https://www.cdc.gov/physicalactivity/basics/pa-health/index.htm (accessed on 3 March 2026).
- World Health Organization. WHO Guidelines on Physical Activity and Sedentary Behaviour. 2020. Available online: https://iris.who.int/bitstream/handle/10665/337001/9789240014886-eng.pdf?sequence=1 (accessed on 3 March 2026).
- Chan, J.S.; Liu, G.; Liang, D.; Deng, K.; Wu, J.; Yan, J.H. Special issue—Therapeutic benefits of physical activity for mood: A systematic review on the effects of exercise intensity, duration, and modality. J. Psychol. 2019, 153, 102–125. [Google Scholar] [CrossRef]
- Nebiker, L.; Lichtenstein, E.; Minghetti, A.; Zahner, L.; Gerber, M.; Faude, O.; Donath, L. Moderating effects of exercise duration and intensity in neuromuscular vs. endurance exercise interventions for the treatment of depression: A meta-analytical review. Front. Psychiatry 2018, 9, 305. [Google Scholar] [CrossRef] [PubMed]
- Brady, S.; D’Ambrosio, L.A.; Felts, A.; Rula, E.Y.; Kell, K.P.; Coughlin, J.F. Reducing isolation and loneliness through membership in a fitness program for older adults: Implications for health. J. Appl. Gerontol. 2020, 39, 301–310. [Google Scholar] [CrossRef] [PubMed]
- Firth, J.; Solmi, M.; Wootton, R.E.; Vancampfort, D.; Schuch, F.B.; Hoare, E.; Gilbody, S.; Torous, J.; Teasdale, S.B.; Jackson, S.E.; et al. A meta-review of “lifestyle psychiatry”: The role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders. World Psychiatry 2020, 19, 360–380. [Google Scholar] [CrossRef] [PubMed]
- Herbert, C.; Meixner, F.; Wiebking, C.; Gilg, V. Regular physical activity, short-term exercise, mental health, and well-being among university students: The results of an online and a laboratory study. Front. Psychol. 2020, 11, 509. [Google Scholar] [CrossRef]
- Chang, C.K.; Chesney, E.; Teng, W.N.; Hollandt, S.; Pritchard, M.; Shetty, H.; Stewart, R.; McGuire, P.; Patel, R. Life expectancy, mortality risks and cause of death in patients with serious mental illness in South East London: A comparison between 2008–2012 and 2013–2017. Psychol. Med. 2023, 53, 887–896. [Google Scholar] [CrossRef]
- Marselle, M.R.; Irvine, K.N.; Warber, S.L. Examining group walks in nature and multiple aspects of well-being: A large-scale study. Ecopsychology 2014, 6, 134–147. [Google Scholar] [CrossRef]
- Arumugam, N.; Parasher, R.K. Effect of physical exercises on attention, motor skill and physical fitness in children with attention deficit hyperactivity disorder: A systematic review. ADHD Atten. Deficit Hyperact. Disord. 2019, 11, 125–137. [Google Scholar]
- Bottoms, L.; Prat Pons, M.; Fineberg, N.A.; Pellegrini, L.; Fox, O.; Wellsted, D.; Drummond, L.M.; Reid, J.; Baldwin, D.S.; Hou, R.; et al. Effects of exercise on obsessive-compulsive disorder symptoms: A systematic review and meta-analysis. Int. J. Psychiatry Clin. Pract. 2022, 27, 232–242. [Google Scholar] [CrossRef]
- Fernández-Abascal, B.; Suárez-Pinilla, P.; Cobo-Corrales, C.; Crespo-Facorro, B.; Suárez-Pinilla, M. In-and outpatient lifestyle interventions on diet and exercise and their effect on physical and psychological health: A systematic review and meta-analysis of randomised controlled trials in patients with schizophrenia spectrum disorders and first episode of psychosis. Neurosci. Biobehav. Rev. 2021, 125, 535–568. [Google Scholar]
- Morres, I.D.; Hatzigeorgiadis, A.; Stathi, A.; Comoutos, N.; Arpin-Cribbie, C.; Krommidas, C.; Theodorakis, Y. Aerobic exercise for adult patients with major depressive disorder in mental health services: A systematic review and meta-analysis. Depress. Anxiety 2019, 36, 39–53. [Google Scholar] [CrossRef]
- Whitworth, J.W.; Ciccolo, J.T. Exercise and post-traumatic stress disorder in military veterans: A systematic review. Mil. Med. 2016, 181, 953–960. [Google Scholar] [CrossRef] [PubMed]
- Pearce, M.; Garcia, L.; Abbas, A.; Strain, T.; Schuch, F.B.; Golubic, R.; Kelly, P.; Khan, S.; Utukuri, M.; Laird, Y.; et al. Association between physical activity and risk of depression: A systematic review and meta-analysis. JAMA Psychiatry 2022, 79, 550–559. [Google Scholar] [CrossRef] [PubMed]
- Mittal, V.A.; Vargas, T.; Osborne, K.J.; Dean, D.; Gupta, T.; Ristanovic, I.; Hooker, C.I.; Shankman, S.A. Exercise treatments for psychosis: A review. Curr. Treat. Options Psychiatry 2017, 4, 152–166. [Google Scholar] [CrossRef] [PubMed]
- Basavaraddi, I.V. Yoga: Its Origin, History and Development. Ministry of External Affairs of Government of India. 2015. Available online: http://www.redtwigyoga.com/uploads/1/2/1/9/12195443/yoga__its_origin_history_and_development.pdf (accessed on 3 March 2026).
- Raghuwanshi, A. A review: History of revival of yoga in 20th century and establishment of yoga as a science in the 21st century. Sci. Interdiscip. Yoga Res. 2011, 1, 208–216. [Google Scholar]
- de Manincor, M.; Bensoussan, A.; Smith, C.; Fahey, P.; Bourchier, S. Establishing key components of yoga interventions for reducing depression and anxiety, and improving well-being: A Delphi method study. BMC Complement. Altern. Med. 2015, 15, 85. [Google Scholar] [CrossRef]
- Matko, K.; Bringmann, H.C.; Sedlmeier, P. Effects of different components of yoga: A meta-synthesis. OBM Integr. Complement. Med. 2021, 6, 030. [Google Scholar] [CrossRef]
- Matson, M. There are Only 4 Types of Yoga. Book Retreats. 2023. Available online: https://bookretreats.com/blog/types-of-yoga/ (accessed on 3 March 2026).
- Pathare, S. Types of Yoga Asanas—A Complete Guide. HealthyMe. 2023. Available online: https://yogamedicine.com/guide-types-yoga-styles/ (accessed on 3 March 2026).
- Cramer, H.; Lauche, R.; Langhorst, J.; Dobos, G. Is one yoga style better than another? A systematic review of associations of yoga style and conclusions in randomized yoga trials. Complement. Ther. Med. 2016, 25, 178–187. [Google Scholar] [CrossRef]
- Wieland, L.S.; Cramer, H.; Lauche, R.; Verstappen, A.; Parker, E.A.; Pilkington, K. Evidence on yoga for health: A bibliometric analysis of systematic reviews. Complement. Ther. Med. 2021, 60, 102746. [Google Scholar] [CrossRef]
- Klatte, R.; Pabst, S.; Beelmann, A.; Rosendahl, J. The efficacy of body-oriented yoga in mental disorders: A systematic review and meta-analysis. Dtsch. Ärzteblatt Int. 2016, 113, 195–202. [Google Scholar]
- National Library of Medicine; National Center for Biotechnology Information. Meta-Analysis, Review, Systematic Review, in the Last 5 Years; National Institute of Health, US Department of Health and Human Services: Washington, DC, USA, 2022.
- Bridges, L.; Sharma, M. The efficacy of yoga as a form of treatment for depression. J. Evid.-Based Complement. Altern. Med. 2017, 22, 1017–1028. [Google Scholar] [CrossRef]
- Brinsley, J.; Schuch, F.; Lederman, O.; Girard, D.; Smout, M.; Immink, M.A.; Stubbs, B.; Firth, J.; Davison, K.; Rosenbaum, S. Effects of yoga on depressive symptoms in people with mental disorders: A systematic review and meta-analysis. Br. J. Sports Med. 2021, 55, 992–1000. [Google Scholar] [CrossRef] [PubMed]
- Meister, K.; Becker, S. Yoga bei psychischen Störungen. Der Nervenarzt 2018, 89, 994–998. [Google Scholar] [CrossRef] [PubMed]
- Da Silva, T.L.; Ravindran, L.N.; Ravindran, A.V. Yoga in the treatment of mood and anxiety disorders: A review. Asian J. Psychiatry 2009, 2, 6–16. [Google Scholar] [CrossRef] [PubMed]
- Alici, N.K.; Dönmez, A.A. A systematic review of the effect of laughter yoga on physical function and psychosocial outcomes in older adults. Complementary Ther. Clin. Pract. 2020, 41, 101252. [Google Scholar] [CrossRef]
- Öztürk, F.Ö.; Bayraktar, E.P.; Tezel, A. The effect of laughter yoga on loneliness, psychological resilience, and quality of life in older adults: A pilot randomized controlled trial. Geriatr. Nurs. 2023, 50, 208–214. [Google Scholar] [CrossRef]
- Sabori, Z.; Khayatan, F.; Ghanavat, M. The effect of Kataria Laughter Training (Laughter Yoga) on hopelessness and loneliness in children with leukemia. Q. J. Child Ment. Health 2019, 5, 182–193. [Google Scholar]
- Kamraju, M. The impact of yoga on mental health. Indones. J. Community Spec. Needs Educ. 2023, 3, 141–146. [Google Scholar] [CrossRef]
- Pascoe, M.C.; Thompson, D.R.; Ski, C.F. Yoga, mindfulness-based stress reduction and stress-related physiological measures: A meta-analysis. Psychoneuroendocrinology 2017, 86, 152–168. [Google Scholar] [CrossRef]
- Teoh, S.L.; Letchumanan, V.; Lee, L.H. Can mindfulness help to alleviate loneliness? A systematic review and meta-analysis. Front. Psychol. 2021, 12, 633319. [Google Scholar] [CrossRef]
- Williams, K.; Hartley, S.; Langer, S.; Manandhar-Richardson, M.; Sinha, M.; Taylor, P. A systematic review and meta-ethnographic synthesis of Mindfulness-based Cognitive Therapy for people with major depression. Clin. Psychol. Psychother. 2022, 29, 1494–1514. [Google Scholar] [CrossRef]
- Zhang, D.; Lee, E.K.; Mak, E.C.; Ho, C.Y.; Wong, S.Y. Mindfulness-based interventions: An overall review. Br. Med. Bull. 2021, 138, 41–57. [Google Scholar] [CrossRef]
- Lin, J.; Gao, Y.F.; Guo, Y.; Li, M.; Zhu, Y.; You, R.; Chen, S.; Wang, S. Effects of qigong exercise on the physical and mental health of college students: A systematic review and Meta-analysis. BMC Complement. Med. Ther. 2022, 22, 287. [Google Scholar] [CrossRef] [PubMed]
- Toneti, B.F.; Barbosa, R.F.M.; Mano, L.Y.; Sawada, L.O.; Oliveira, I.G.D.; Sawada, N.O. Benefits of Qigong as an integrative and complementary practice for health: A systematic review. Rev. Lat.-Am. De Enferm. 2020, 28, e3317. Available online: https://www.scielo.br/j/rlae/a/fN4wqKbwXNyyn9snptrr5TC/?lang=en&format=html (accessed on 3 March 2026). [CrossRef] [PubMed]
- Wang, F.; Lee, E.K.O.; Wu, T.; Benson, H.; Fricchione, G.; Wang, W.; Yeung, A.S. The effects of tai chi on depression, anxiety, and psychological well-being: A systematic review and meta-analysis. Int. J. Behav. Med. 2014, 21, 605–617. [Google Scholar] [CrossRef] [PubMed]
- Xianjian, C.; Datao, X. Effects of tai Chi Chuan on the physical and mental health of the elderly: A systematic review. Phys. Act. Health 2021, 5, 21–27. [Google Scholar] [CrossRef]
- Aftab, A.; Druss, B.G. Addressing the mental health crisis in youth—Sick individuals or sick societies? JAMA Psychiatry 2023, 80, 863–864. [Google Scholar] [CrossRef]
- Bakolis, I.; Hammoud, R.; Stewart, R.; Beevers, S.; Dajnak, D.; MacCrimmon, S.; Broadbent, M.; Pritchard, M.; Shiode, N.; Fecht, D.; et al. Mental health consequences of urban air pollution: Prospective population-based longitudinal survey. Soc. Psychiatry Psychiatr. Epidemiol. 2021, 56, 1587–1599. [Google Scholar] [CrossRef]
- Buoli, M.; Grassi, S.; Caldiroli, A.; Carnevali, G.S.; Mucci, F.; Iodice, S.; Cantone, L.; Pergoli, L.; Bollati, V. Is there a link between air pollution and mental disorders? Environ. Int. 2018, 118, 154–168. [Google Scholar] [CrossRef]
- Chen, S.; Oliva, P.; Zhang, P. Air pollution and mental health: Evidence from China. AEA Pap. Proc. 2024, 114, 423–428. [Google Scholar] [CrossRef]
- Appenzeller, T. Good morning, sunshine: The seemingly unstoppable growth of renewable energy is Science’s 2025 Breakthrough of the Year. Science 2025, 390, 1208–1209. [Google Scholar] [CrossRef]
- Bingley, W.J.; Tran, A.; Boyd, C.P.; Gibson, K.; Kalokerinos, E.K.; Koval, P.; Kashima, Y.; McDonald, D.; Greenaway, K.H. A multiple needs framework for climate change anxiety interventions. Am. Psychol. 2022, 77, 812–821. [Google Scholar] [CrossRef]
- Palinkas, L.A.; O’Donnell, M.L.; Lau, W.; Wong, M. Strategies for delivering mental health services in response to global climate change: A narrative review. Int. J. Environ. Res. Public Health 2020, 17, 8562. [Google Scholar] [CrossRef]
| Barrier Type | Brief Description |
|---|---|
| System Factors Cost of mental health services | Treatment is not affordable because services are not covered by the client’s insurance, are not completely covered, or the out-of-pocket costs are too high. Understanding what is and is not covered or negotiating the process of this (reimbursement forms, appealing after a claim has been refused) can be daunting. |
| Policy and legal constraints | Government (e.g., federal, state, province, and city) as well as third-party payers’ policies may restrict what conditions can be treated and reimbursed or for how long treatment can be provided (e.g., number of sessions, days) and still be reimbursed. These limit what services may be available. |
| Too few providers to deliver services | Mental health professionals are not available in sufficient numbers to meet the need. This is a global problem in low-, middle-, and high-income countries. Too few service providers meet the ethnic demographic profiles of the public and may not focus on clinical populations or problems for which the need is great. |
| Attitudinal Factors Stigma | Concerns among potential clients or consumers of treatment include being labeled (diagnosed) with a mental disorder or being associated with treatment for a mental disorder. Stigma can lead to genuine discriminatory practices and domains of rejection (e.g., employment, promotion). Also, individuals may view their own problems with stigma (self-stigma), which can interfere with seeking treatment. |
| Mental health literacy | Information individuals have and what they know about mental disorders, whether one has symptoms or a disorder that warrants treatment, what the options are for treatment, and how to pursue those options and obtain treatment. |
| Ethnic and cultural influences | Ethnic and underrepresented groups within a culture have less access to services for health care in general, including mental health care. Views about whether psychological problems warrant treatment, entry into any health care service, and seeking treatment can vary widely. Some problems (e.g., anxiety, depression) may not be seen as a reason to seek “treatment” or to be involved with a health care system. |
| Medium | Defined |
|---|---|
| Telepsychiatry/ Telemedicine | Treatment provided at a distance originally dominated by telephone, but more recently provided by video. |
| Applications (apps) and the Internet (E-mental health) | E (electronic)-mental health includes a range of services and platforms such as applications (“apps”), the internet, games for smart devices, websites, wearable sensors, and social media. |
| Chatbots | A software or internet application that is designed to mimic human conversation through text or voice interactions. They simulate conversations with humans. |
| Short Message Service (SMS) | A way of sending text messages, which permits the exchange of these messages between mobile devices and other smart devices. |
| Virtual Reality & Augmented Reality | VR provides a computer-generated three-dimensional (3D) simulation experience that delivers a realistic rendition of images, sounds, and occasionally olfactory and tactile stimuli. One interacts in a realistic way using specialized equipment, usually a headset display. VR can create realistic settings and situations to provide individuals with the experience of being present in the specific setting or situation. AR is a computer-generated simulation. Instead of being completely artificial and simulated as in VR, AR permits one to add images, sounds, graphics, and characters (avatars to represent people) to real environments that appear to the participant. |
| Socially Assistive Robots | Robots that can interact with humans. They often draw on artificial intelligence, large or natural language models (to develop natural or conversational language), and machine learning to guide interactions. They help users in social rather than physical interactions and can provide guidance, support, motivation, and feedback toward a specific goal (e.g., education, learning, and training). |
| Activity | Defined |
|---|---|
| Physical Activity/Exercise | Physical activity refers to engaging in movement or action that is sustained for a specific period of time and includes both structured activities (e.g., games, sports, and exercise classes) and unstructured activities (e.g., going for walks, doing household chores, and gardening). |
| Contact with Nature | Interaction with some facet of the natural environment, including wilderness, mountains, forests, oceans, lakes, and other open areas. Gardens and parks with foliage, nonhuman animals, and more generally the sights, sounds, fragrances, and ambience of the outdoors are central, whether in a city or a wilderness area. |
| Diet and Nutrition | Foods, beverages, nutrients (e.g., vitamins, minerals), and special multicomponent nutritional supplements that can be consumed and are intended to improve health. |
| Yoga | A spiritual discipline and set of practices designed to bring harmony between the mind and body. Encompasses many components that include a variety of movements, postures, breath control, relaxation, mindfulness, and meditation. |
| Tai Chi/Qigong | Tai chi has an overall goal to connect mind, body, and spirit and bring serenity to the individual. The practice includes sequences of very slow, controlled, and flowing movements to address strength, endurance, balance, and mobility of the body. Qigong involves breathing patterns (slow, long, and combining with speech), movements of the whole body that are slow, smooth and directed toward achieving a relaxed state and focusing one’s attention. |
| Mindfulness and Meditation | Mindfulness is directed toward attaining liberation from the impermanence of nature and suffering. Key components are focusing on the present moment, observing or being aware of one’s thoughts, emotions, sensations and momentary experiences, and adopting a nonjudgmental attitude towards one’s experience of the internal or external world. Meditation emphasizes the importance of attention focused on an object or single thought until the mind achieves calmness and quieting of intrusive other thoughts. |
| Social Contacts | Interaction with others that can take many forms, depending on the contacts (e.g., family, friends, teachers, colleagues, and peers), diverse settings (e.g., work, at school, and community) and whether contacts are in person and face-to-face or through a variety of media. |
| Interactions with Pets and Other Nonhuman Animals | Contact with animals in diverse contexts—most commonly with one’s pet, but also includes emotional support animals, and animal visitation programs. |
| Spirituality and Religion | Spirituality refers to the search for meaning in life and a belief in a broad or transcendental realm beyond the mundane and everyday experience. Religion is an institutionalized system of practices, beliefs, and attitudes. |
| Volunteering | Participating in an activity in which one gives time and effort to provide some service or assistance, invariably without receiving external compensation. The service is intended to directly benefit someone else or an agency that serves others. |
| Hobbies and Leisure Activities | An activity or interest that is pursued for enjoyment and relaxation, often done in one’s spare time and for which there usually is no interest in making a profit. |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Kazdin, A.E. Extending the Reach of Interventions to Treat Mental Disorders. Psychiatry Int. 2026, 7, 78. https://doi.org/10.3390/psychiatryint7020078
Kazdin AE. Extending the Reach of Interventions to Treat Mental Disorders. Psychiatry International. 2026; 7(2):78. https://doi.org/10.3390/psychiatryint7020078
Chicago/Turabian StyleKazdin, Alan E. 2026. "Extending the Reach of Interventions to Treat Mental Disorders" Psychiatry International 7, no. 2: 78. https://doi.org/10.3390/psychiatryint7020078
APA StyleKazdin, A. E. (2026). Extending the Reach of Interventions to Treat Mental Disorders. Psychiatry International, 7(2), 78. https://doi.org/10.3390/psychiatryint7020078
