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Engineering Proceedings
Volume 150
Issue 1
10.3390/engproc2026150029
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Proceeding Paper

Conceptual Model and Software Architecture for Bioinformatics Data Analysis and Diagnosis in Support of Precision Medicine †

by
Boris Nenchovski
* and
Desislava Ivanova
Faculty of Applied Mathematics and Informatics, Technical University of Sofia, 1756 Sofia, Bulgaria
*
Author to whom correspondence should be addressed.
†
Presented at the 15th International Scientific Conference TechSys 2026—Engineering, Technologies and Systems, Plovdiv, Bulgaria, 14–16 May 2026.
Eng. Proc. 2026, 150(1), 29; https://doi.org/10.3390/engproc2026150029
Published: 20 July 2026
(This article belongs to the Proceedings of The 15th International Scientific Conference TechSys 2026—Engineering, Technologies and Systems)
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Abstract

This paper proposes a novel three-layered software architecture for processing and analyzing sequences, medical images, and patient-reported outcomes (PROs). The aim is to provide a comprehensive end-to-end solution for patient diagnosis by integrating all major types of bioinformatics data. This approach leverages advanced machine learning algorithms, including decision trees, support vector machines, neural networks, and quantum neural networks, to enhance the efficiency and effectiveness of precision medicine. A graphical user interface was constructed to validate the suggested approach and present the experimental results.
Keywords: sequences; medical images; patient-reported outcomes; neural networks; quantum neural networks; precision medicine sequences; medical images; patient-reported outcomes; neural networks; quantum neural networks; precision medicine

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MDPI and ACS Style

Nenchovski, B.; Ivanova, D. Conceptual Model and Software Architecture for Bioinformatics Data Analysis and Diagnosis in Support of Precision Medicine. Eng. Proc. 2026, 150, 29. https://doi.org/10.3390/engproc2026150029

AMA Style

Nenchovski B, Ivanova D. Conceptual Model and Software Architecture for Bioinformatics Data Analysis and Diagnosis in Support of Precision Medicine. Engineering Proceedings. 2026; 150(1):29. https://doi.org/10.3390/engproc2026150029

Chicago/Turabian Style

Nenchovski, Boris, and Desislava Ivanova. 2026. "Conceptual Model and Software Architecture for Bioinformatics Data Analysis and Diagnosis in Support of Precision Medicine" Engineering Proceedings 150, no. 1: 29. https://doi.org/10.3390/engproc2026150029

APA Style

Nenchovski, B., & Ivanova, D. (2026). Conceptual Model and Software Architecture for Bioinformatics Data Analysis and Diagnosis in Support of Precision Medicine. Engineering Proceedings, 150(1), 29. https://doi.org/10.3390/engproc2026150029

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