Quality of Life in Patients with Obesity: The Role of Multidisciplinary Rehabilitation Medicine
Abstract
:1. Introduction
2. Patients and Methods
2.1. Setting and Study Population
2.2. The Multidisciplinary Rehabilitation Program
2.2.1. Exercise Intervention
2.2.2. Nutrition Program
2.2.3. Psychological Support
2.3. Outcome Measures
2.3.1. Anthropometric and Cardiometabolic Measurements
2.3.2. Physical Fitness Assessment
2.3.3. Pain Assessment
2.3.4. Psychiatric Assessment
2.3.5. Health-Related Quality of Life (QoL) Assessment
3. Statistical Analysis
4. Results
4.1. Demographics and Medical Conditions of the Participants
4.2. Change in Parameters after the Rehabilitation Program
4.2.1. Anthropometric Parameters
4.2.2. Functional Parameters
4.2.3. Quality of Life and Psychiatric Symptoms
5. Discussion
Strengths and Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Demographics | N = 124 (100%) |
---|---|
Gender (M/F) | 44/80 |
Age (years) (mean ± SD) | 57 ± 12 |
Smoking | |
Current | 22 (13%) |
Former | 25 (25%) |
Never | 77 (62%) |
Medical conditions | |
Hypertension, n (%) | 72 (58%) |
Type 2 Diabetes | 45 (36%) |
Dyslipidemia | 26 (21%) |
Obstructive Sleep Apnea | 69 (56%) |
Arthritis | 95 (77%) |
Mood Disorders | 51 (41%) |
Variable | Baseline | Post Intervention | p-Value |
---|---|---|---|
General measures | <0.05 | ||
Body weight (kg) | 125.7 ± 34.5 | 116.8 ± 30.5 | 0.0354 |
BMI (kg/m2) | 46.2 ± 10 | 42.8 ± 9 | 0.0088 |
Waist circumference, cm | 129.7 ± 18 | 121.5 ± 17 | 0.0013 |
Systolic blood pressure, mm Hg | 127 ± 13 | 116 ± 9 | <0.0001 |
Diastolic blood pressure, mm Hg | 70 ± 10 | 65 ± 8 | 0.0002 |
Bioelectrical impedance analysis, mean ± SD | |||
Body fat (%) | |||
Fat mass (kg) | 57.9 ± 16.9 | 51.2 ± 15.3 | 0.0031 |
Lean mass (kg) | 63.0 ± 15.5 | 61.3 ± 15.6 | 0.4167 |
Estimated resting energy expenditure (kcal/day) | 2040 ± 506 | 1950 ± 507 | 0.1868 |
Laboratory measures | |||
Hemoglobin A1c, (%) | 6.73 ± 1.61 | 6.43 ± 3.84 | 0.5049 |
Total cholesterol, mg/dL | 1.9 ± 0.4 | 1.7 ± 0.4 | 0.0022 |
HDL cholesterol, mg/dL | 0.50 ± 0.12 | 0.45 ± 0.10 | 0.0004 |
LDL cholesterol, mg/dL | 1.17 ± 0.37 | 1.06 ± 0.33 | 0.0155 |
Triglycerides, mg/dL | 1.69 ± 0.97 | 1.58 ± 0.72 | 0.3535 |
GGT (IU/L) | 49 [31–97] | 46 [29.5–75] | 0.2796 |
C-reactive protein, mg/L | 9.6 [5.0–13.8] | 6.3 [3.0–10.8] | 0.1455 |
TSH (mUI/L) (N: 0.4–4) | 1.72 [1.06–2.39] | 1.60 [1.02–2.22] | 0.1133 |
Serum albuminemia (g/L) | 35.9 ± 3.0 | 36.0 ± 3.3 | 0.7358 |
Serum creatininemia (mg/L) | 8.14 ± 1.94 | 8.17 ± 2.10 | 0.9132 |
Functional Parameters | |||
6MWT, distance walked (m) | 324 ± 156 | 441 ± 149 | <0.0001 |
Pain scale (range: 0–10) | 5.8 ± 2.4 | 3.4 ± 2.2 | <0.0001 |
HADS | |||
Anxiety score | 9.1 ± 4.2 | 7.9 ± 4.5 | <0.001 |
Depression score | 7.6 ± 4.5 | 5.8 ± 4 | <0.001 |
Quality of Life Scale, Obesity and Dietetics | Baseline | Post Intervention | p Value |
---|---|---|---|
Physical impact | 54.3 ± 15.7 | 67.6 ± 16.5 | <0.0001 |
Psychosocial impact | 59.8 ± 19.4 | 70.8 ± 18.7 | <0.0001 |
Impact on sex life | 60.9 ± 26.7 | 70.8 ± 27,3 | 0.0131 |
Nutritional well-being | 63.5 ± 19.4 | 62.6 ± 18.5 | 0.7318 |
Food rebalancing | 65.4 ± 19.2 | 73.1 ± 17.4 | 0.0011 |
Total score | 60.8 ± 11.9 | 68.8 ± 12.3 | <0.0001 |
Univariate Analysis | Multivariate Analysis | |||
---|---|---|---|---|
Regression Coefficient (95% CI) | p Value | Regression Coefficient (95% CI) | p Value | |
Change in anxiety score | −1.01 [−1.46; −0.57] | <0.001 | −0.48 [−0.92; −0.05] | 0.0327 |
Change in depression score | −1.32 [−1.69; −0.94] | <0.001 | −1.09 [−1.48; −0.70] | <0.0001 |
Change in pain score | −0.77 [−1.72; 0.17] | 0.108 | ||
Change in 6MWT | −0.01 [−0.05; 0.03] | 0.733 | ||
Change in lean mass | −0.37 [−0.62; −0.12] | 0.005 | −0.31 [−0.54; −0.08] | 0.0120 |
Change in fat mass | −0.27 [−0.55; 0.01] | 0.060 | −0.25 [−0.48; −0.008] | 0.0461 |
Change in weight loss | −0.44 [−0.70; −0.17] | 0.001 |
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Kouidrat, Y.; Louhou, R.; Mondot, C.; Daami, I.; Amad, A.; Diouf, M. Quality of Life in Patients with Obesity: The Role of Multidisciplinary Rehabilitation Medicine. Obesities 2024, 4, 160-168. https://doi.org/10.3390/obesities4020015
Kouidrat Y, Louhou R, Mondot C, Daami I, Amad A, Diouf M. Quality of Life in Patients with Obesity: The Role of Multidisciplinary Rehabilitation Medicine. Obesities. 2024; 4(2):160-168. https://doi.org/10.3390/obesities4020015
Chicago/Turabian StyleKouidrat, Youssef, Rufin Louhou, Claire Mondot, Imed Daami, Ali Amad, and Momar Diouf. 2024. "Quality of Life in Patients with Obesity: The Role of Multidisciplinary Rehabilitation Medicine" Obesities 4, no. 2: 160-168. https://doi.org/10.3390/obesities4020015
APA StyleKouidrat, Y., Louhou, R., Mondot, C., Daami, I., Amad, A., & Diouf, M. (2024). Quality of Life in Patients with Obesity: The Role of Multidisciplinary Rehabilitation Medicine. Obesities, 4(2), 160-168. https://doi.org/10.3390/obesities4020015