Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review
Abstract
:1. Introduction
2. Antibiotics and Electrochemical Detection
3. Relevant Aspects in the Development of Electrochemical Aptasensors
3.1. Nanomaterial-Modified Electrochemical Aptasensors
3.2. Configurations of Electrochemical Aptasensors
4. Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Antibiotic | Technique | Modification | Sample | Detection Range | Limit of Detection (LOD) | Ref. |
---|---|---|---|---|---|---|
Tetracycline | DPV | Cu2O@Au | milk | 1.0 nM–1000 µM | 0.16 nM | [50] |
Streptomycin | EIS | Pencil lead graphite-based electrochemical aptasensor | milk | 10−8–10−16 M | 0.8 × 10−18 M | [51] |
Oxytetracycline | DPV | 4-carboxyphenyl anchored GCE | milk | 1.0 × 10−9–1.0 × 10−4 g mL−1 | 2.29 × 10−10 g mL−1 | [52] |
Ampicillin | LSV | MWCNTs | milk | 1.0 × 10−13–1.0 × 10−8 M | 1.0 × 10−13 | [53] |
Amoxicillin | EIS | TiO2-g-C3N4@Au NPs | wastewater | 0.5–3 nM | 0.2 nM | [54] |
Ampicillin | DPV | Endonuclease DpnII | milk and water | 0.1–100 nM | 32 pM | [55] |
Ampicillin | EIS | Co-MOF@TPN-COF | human serum, river water, and milk | 1.0 fg mL−1 –2.0 ng mL−1 | 0.217 fg mL−1 | [56] |
Tetracycline | SWV | Aptamer cocktail | honey | 0.01–1000 ng mL−1 | 0.0073 ng/mL | [57] |
Ciprofloxacin | DPV | rGO/PEI/TiO2 | water | 0.003–10.0 μM | 0.7 nM | [58] |
Streptomycin | DPV | PCNR/GR–Fe3O4–AuNPs | milk | 0.05–200 ng mL−1 | 0.028 ng mL −1 | [59] |
Kanamycin | DPV | MoS2-Au-HE | milk | 1.0–1.0 × 105 ng L −1 | 0.8 ng L−1 | [60] |
Sulfaquinoxaline | DPV | AuPd NPs@UiO-66-NH2/CoSe2 | pork | 1.0–100 ng mL−1 | 0.547 pg mL −1 | [61] |
Tetracycline | EIS | Fe3O4-IL | milk | 1 × 10−9–1 × 10−5 M | 1 × 10−9 M | [62] |
Tetracycline | SWV | PAN@Cu-BTC | meat | 10 pM–1 µM | 0.32 pM | [63] |
Tobramycin | DPV | phi29 DNA polymerase and nicking endonuclease Nt.AlwI | milk and water | 10–200 nM | 5.13 nM | [64] |
Tobramycin | EIS | SnOx@TiO2@mC | human serum and human urine | 0.01–5 ng mL−1 | 6.7 pg mL−1 | [65] |
Kanamycin | DPV | SA-AuNPs/OMC-CS | milk | 0.1–1000 nM | 0.03569 nM | [66] |
Streptomycin | EIS | PdNPs/CNT/Chi | milk | 0.10–1500 nM | 18 pM | [67] |
Chloramphenicol | DPV | Si-Fe/NOMC | eye drop | 1.0–500 μM | 0.03 μM | [68] |
Ampicillin | EIS | POP | milk | 1.0 × 10–5–5.0 ng mL−1 | 1.33 × 10–6 | [69] |
Ciprofloxacin | DPV | 3D Au-PAMAM/rGO | raw milk | 1 μM–1.0 nM | 1.0 nM | [70] |
Kanamycin | DPV | GR-TH/HNP-PtCu | pork meat and chicken | 5 × 10−7–5 × 10−2 μg mL−1 | 0.42 pg mL−1 | [71] |
Tetracycline | DPV | MBCPE/Fe3O4NPs/OA | drug, milk, honey, and blood serum | 1.0 × 10−10–1.0 × 10−7 M | 2.9 × 10−11 M | [72] |
Tetracycline | DPV | C-WO3@AuNPs | water, milk, honey, and black tea | 0.1–100 nM | 4.8 × 10−2 nM | [73] |
Enrofloxacin | SWV | AuPt@h-CeO2/MoS2 | water and milk | 5.0 × 10−6–1.0 × 10−2 ng mL−1 | 1.02 × 10−7 ng mL−1 | [74] |
Ampicillin | DPV | T7 exonuclease | milk | 0.02–40 nM | 4.0 pM | [75] |
Chloramphenicol (CAP) and oxytetracycline (OTC) | SWV | NMOF | milk | 10−4–50 nM | CAP 0.033 pM OTC 0.048 pM | [76] |
Antibiotic | Sequences | Ref. |
---|---|---|
Penicillin | 5′-NH2-CTG AATTGGATCTCTCTTCTTGAGCGATCTCCACA-3′ | [91] |
Streptomycin | 5′-NH2-GGGGTCTGGTGTTCTGCTTTGTTCTGTCGGGTCGT-3′ | [92] |
Oxytetracycline | 5′-SH-CGACGCACAGTCGCTGGTGCGTACCTGGTTGCCGTTGTG | [93] |
Kanamycin | 5′-Bio-ACCGCGGGGUUGCGGACCGGGAGCUCCAGC-NH2-3′ | [47] |
Tobramycin | 5′-Bio-GGCACGAGGUUUAGCUACACUCGUGCC-NH2-3′ | [47] |
Streptomycin | (SH-cDNA): 5′-ACGACCCGACAGAACAAAGCAGAACACCAGACCCC-SH-3′ Amino-modified STR aptamer (NH2-Apt): 5′-NH2-GGGGTCTGGTGTTCTGCTTTGTTCTGTCGGGTCGT-3′ | [94] |
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da Silva, D.N.; Pereira, A.C. Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review. Electrochem 2023, 4, 553-567. https://doi.org/10.3390/electrochem4040035
da Silva DN, Pereira AC. Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review. Electrochem. 2023; 4(4):553-567. https://doi.org/10.3390/electrochem4040035
Chicago/Turabian Styleda Silva, Daniela Nunes, and Arnaldo César Pereira. 2023. "Relevant Aspects in the Development of Electrochemical Aptasensors for the Determination of Antibiotics—A Review" Electrochem 4, no. 4: 553-567. https://doi.org/10.3390/electrochem4040035