Molecularly Imprinted Electrochemical Sensor Based on Poly (O-Phenylenediamine) for Sensitive Detection of Oxycodone in Water
Abstract
:1. Introduction
2. Materials and Methods
2.1. Chemicals
2.2. Procedure Preparation of MIP Receptor
3. Results
3.1. Electrochemical Characterization of the Imprinted Sensor Electrodes
3.2. Electrochemical Impedance Spectroscopy (EIS)
3.3. Calibration Curves and Binding Affinity of Oxycodone MIP
3.4. Interference Study
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Electrode-Based | |||
---|---|---|---|
Modified Electrodes | Linear Range | Detection Limit | Reference |
CoFe2O4/CPE | 0.06–38 uM | 0.05 uM | [24] |
Nafion/SWCNT | 0.5–10 μM | 85 nM | [25] |
o-Phenylenediamine polymer imprint | 0.4–5 nM | 1.8 nM | This work |
Other methods | |||
HPLC-UV | 1–2000 ng/mL | 2.67 ng/mL | [26] |
nano-Si-based SALDI-MS. | 0–100 ng/mL | 1.56 ng/mL | [27] |
ELISA combine with GC-MS | 0 to 1000 ng/g | 50 ng/g | [28] |
Silver NPs on zinc oxide, SERS | 900 ug/mL to 90 ng/mL | 90 ng/ mL | [29] |
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Charkravarthula, P.; Mugweru, A. Molecularly Imprinted Electrochemical Sensor Based on Poly (O-Phenylenediamine) for Sensitive Detection of Oxycodone in Water. Electrochem 2023, 4, 435-446. https://doi.org/10.3390/electrochem4040028
Charkravarthula P, Mugweru A. Molecularly Imprinted Electrochemical Sensor Based on Poly (O-Phenylenediamine) for Sensitive Detection of Oxycodone in Water. Electrochem. 2023; 4(4):435-446. https://doi.org/10.3390/electrochem4040028
Chicago/Turabian StyleCharkravarthula, Pranaya, and Amos Mugweru. 2023. "Molecularly Imprinted Electrochemical Sensor Based on Poly (O-Phenylenediamine) for Sensitive Detection of Oxycodone in Water" Electrochem 4, no. 4: 435-446. https://doi.org/10.3390/electrochem4040028