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Article

Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children’s Hospital

by
Silvia Borghetti
1,
Ugo Maria Pierucci
2,3,*,
Chiara Palladino
1,
Stefania Vimercati
1,
Francesca Selmin
4,
Andrea Marcellusi
4,
Giulia Tosi
1,
Alessia Musitelli
2,
Elena Zoia
5,
Irene Paraboschi
2,3 and
Gloria Pelizzo
2,3,*
1
Pharmacy Unit, ASST Fatebenefratelli-Sacco, 20131 Milan, Italy
2
Department of Pediatric Surgery, “V. Buzzi” Children’s Hospital, 20154 Milan, Italy
3
Department of Biomedical and Clinical Science, University of Milano, 20157 Milan, Italy
4
Department of Pharmaceutical Science (DISFARM), University of Milan, 20122 Milan, Italy
5
Anesthesia and Intensive Care Unit, Vittore Buzzi Children’s Hospital, 20154 Milan, Italy
*
Authors to whom correspondence should be addressed.
Eur. Burn J. 2026, 7(1), 8; https://doi.org/10.3390/ebj7010008
Submission received: 22 December 2025 / Revised: 21 January 2026 / Accepted: 2 February 2026 / Published: 5 February 2026
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Abstract

Background: Pediatric burns cause considerable morbidity and hospital resource use. Advanced dressings on moderate-degree pediatric burns that accelerate healing may offset acquisition costs by shortening length of stay (LOS). Objective: The aim of this study was to assess the budget impact of introducing an oxygen-enriched olive-oil dressing for pediatric burns (grade I–IIG; total body surface area < 20%) at a tertiary children’s hospital. Methods: A hospital-perspective budget impact analysis was conducted according to ISPOR guidance over a 4-year horizon (2022–2025). The study population included 32 inpatients (<18 years) with non-extensive, moderate-degree burns treated between 2022 and 2023. Two scenarios were modeled: (i) standard of care (SoC) and (ii) SoC plus the oxygen-enriched olive-oil dressing (OEoD), with annual caseload projections to 2025. Costs combined treatment (dressings, drugs, and devices) and hospitalization data provided by the hospital’s Control & Management Unit. The average daily hospitalization cost was €1438.99. Results: Compared with SoC, the OEoD scenario increased per-patient dressing costs (mean €271.4 vs. €121.9) but reduced LOS (mean 7.3 vs. 16.6 days), leading to lower overall hospitalization expenditure. Total annual costs decreased by 7%, 13%, 16%, and 18% across 2022–2025, respectively (for example, 2025: €612,516 vs. €751,445; Δ −€138,929). Cumulative 4-year savings reached €337,399. Deterministic sensitivity analysis confirmed the robustness of these findings, with savings persisting under variable assumptions. Conclusions: Despite higher acquisition costs, oxygen-enriched olive-oil dressings were associated with shorter LOS and meaningful budget savings in pediatric burn care. These results support their integration into multidisciplinary burn management pathways and call for further prospective multicenter validation.
Keywords: pediatric burns; advanced wound dressing; oxygen-enriched olive-oil dressing; budget impact analysis; hospital costs pediatric burns; advanced wound dressing; oxygen-enriched olive-oil dressing; budget impact analysis; hospital costs

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MDPI and ACS Style

Borghetti, S.; Pierucci, U.M.; Palladino, C.; Vimercati, S.; Selmin, F.; Marcellusi, A.; Tosi, G.; Musitelli, A.; Zoia, E.; Paraboschi, I.; et al. Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children’s Hospital. Eur. Burn J. 2026, 7, 8. https://doi.org/10.3390/ebj7010008

AMA Style

Borghetti S, Pierucci UM, Palladino C, Vimercati S, Selmin F, Marcellusi A, Tosi G, Musitelli A, Zoia E, Paraboschi I, et al. Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children’s Hospital. European Burn Journal. 2026; 7(1):8. https://doi.org/10.3390/ebj7010008

Chicago/Turabian Style

Borghetti, Silvia, Ugo Maria Pierucci, Chiara Palladino, Stefania Vimercati, Francesca Selmin, Andrea Marcellusi, Giulia Tosi, Alessia Musitelli, Elena Zoia, Irene Paraboschi, and et al. 2026. "Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children’s Hospital" European Burn Journal 7, no. 1: 8. https://doi.org/10.3390/ebj7010008

APA Style

Borghetti, S., Pierucci, U. M., Palladino, C., Vimercati, S., Selmin, F., Marcellusi, A., Tosi, G., Musitelli, A., Zoia, E., Paraboschi, I., & Pelizzo, G. (2026). Oxygen-Enriched Olive-Oil Dressing in Moderate-Degree Pediatric Burns: Impact on Care and Budget over a 4-Year Period in a Tertiary Children’s Hospital. European Burn Journal, 7(1), 8. https://doi.org/10.3390/ebj7010008

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