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Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases

1
Laboratorio de Neurobiología del Sueño, Departamento de Fisiología, Facultad de Medicina, Universidad de la República, Av. Gral. Flores 2125, Montevideo 11800, Uruguay
2
Department of Anesthesiology, University of Michigan, 7433 Medical Science Building 1, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5615, USA
3
Department of Psychiatry, University of Wisconsin, 6001 Research Park Blvd, Madison, WI 53719, USA
*
Author to whom correspondence should be addressed.
Clocks & Sleep 2020, 2(4), 536-556; https://doi.org/10.3390/clockssleep2040039
Received: 22 September 2020 / Revised: 28 November 2020 / Accepted: 3 December 2020 / Published: 9 December 2020
(This article belongs to the Section Clocks & Sleep in Animal Basic Research)
The sleep-wake cycle is constituted by three behavioral states: wakefulness (W), non-REM (NREM) and REM sleep. These states are associated with drastic changes in cognitive capacities, mostly determined by the function of the thalamo-cortical system, whose activity can be examined by means of intra-cranial electroencephalogram (iEEG). With the purpose to study in depth the basal activity of the iEEG in adult rats, we analyzed the spectral power and coherence of the iEEG during W and sleep in the paleocortex (olfactory bulb), and in neocortical areas. We also analyzed the laterality of the signals, as well as the influence of the light and dark phases. We found that the iEEG power and coherence of the whole spectrum were largely affected by behavioral states and highly dependent on the cortical areas recorded. We also determined that there are night/day differences in power and coherence during sleep, but not in W. Finally, we observed that, during REM sleep, intra-hemispheric coherence differs between right and left hemispheres. We conclude that the iEEG dynamics are highly dependent on the cortical area and behavioral states. Moreover, there are light/dark phases disparities in the iEEG during sleep, and intra-hemispheric connectivity differs between both hemispheres during REM sleep. View Full-Text
Keywords: sleep; REM; slow waves; oscillations; gamma; spindles sleep; REM; slow waves; oscillations; gamma; spindles
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MDPI and ACS Style

Mondino, A.; Cavelli, M.; González, J.; Osorio, L.; Castro-Zaballa, S.; Costa, A.; Vanini, G.; Torterolo, P. Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases. Clocks & Sleep 2020, 2, 536-556. https://doi.org/10.3390/clockssleep2040039

AMA Style

Mondino A, Cavelli M, González J, Osorio L, Castro-Zaballa S, Costa A, Vanini G, Torterolo P. Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases. Clocks & Sleep. 2020; 2(4):536-556. https://doi.org/10.3390/clockssleep2040039

Chicago/Turabian Style

Mondino, Alejandra, Matías Cavelli, Joaquín González, Lucía Osorio, Santiago Castro-Zaballa, Alicia Costa, Giancarlo Vanini, and Pablo Torterolo. 2020. "Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases" Clocks & Sleep 2, no. 4: 536-556. https://doi.org/10.3390/clockssleep2040039

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