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Measuring Food Anticipation in Mice

Department of Biology, Unit of Biochemistry, University of Fribourg, 1700 Fribourg, Switzerland
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Clocks & Sleep 2019, 1(1), 65-74; https://doi.org/10.3390/clockssleep1010007
Received: 28 September 2018 / Revised: 16 October 2018 / Accepted: 22 October 2018 / Published: 26 October 2018
(This article belongs to the Section Clocks & Sleep in Animal Basic Research)
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Abstract

The interplay between the circadian system and metabolism may give animals an evolutionary advantage by allowing them to anticipate food availability at specific times of the day. Physiological adaptation to feeding time allows investigation of animal parameters and comparison of food anticipation between groups of animals with genetic alterations and/or post pharmacological intervention. Such an approach is vital for understanding gene function and mechanisms underlying the temporal patterns of both food anticipation and feeding. Exploring these mechanisms will allow better understanding of metabolic disorders and might reveal potential new targets for pharmacological intervention. Changes that can be easily monitored and that represent food anticipation on the level of the whole organism are a temporarily restricted increase of activity and internal body temperature. View Full-Text
Keywords: food anticipation; circadian rhythms; chronobiology; peripheral oscillators; mouse activity; wheel running; Period2 (Per2); metabolic disease; feeding; food-entrainable oscillator (FEO) food anticipation; circadian rhythms; chronobiology; peripheral oscillators; mouse activity; wheel running; Period2 (Per2); metabolic disease; feeding; food-entrainable oscillator (FEO)
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Martini, T.; Ripperger, J.A.; Albrecht, U. Measuring Food Anticipation in Mice. Clocks & Sleep 2019, 1, 65-74.

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