Next Article in Journal
A Palatal Speech Bulb—A Case Study
Next Article in Special Issue
Neonatal Intracranial Hemorrhage with a Dramatic Outcome Due to Maternal Anti CD36 Antibodies
Previous Article in Journal
Acknowledgement to Reviewers of Reports in 2018
Article Menu

Export Article

Open AccessCase Report

Early Treatment with Growth Hormone (GH) and Rehabilitation Recovers Hearing in a Child with Cerebral Palsy

1
Otolaryngology, Medical Center Foltra, 15886 Teo, Spain
2
EINA, Medical Center Foltra, 15886 Teo, Spain
3
Speech Therapy, Medical Center Foltra, 15886 Teo, Spain
4
Physiotherapy, Medical Center Foltra, 15886 Teo, Spain
5
Scientific Direction, Medical Center Foltra, 15886 Teo, Spain
*
Authors to whom correspondence should be addressed.
Received: 30 December 2018 / Revised: 20 January 2019 / Accepted: 24 January 2019 / Published: 24 January 2019
(This article belongs to the Special Issue Case Reports in Pediatrics)
  |  
PDF [3182 KB, uploaded 31 January 2019]
  |     |  

Abstract

Neonatal hearing loss is one of the most common anomalies and is frequently associated with delivery problems. The effects of growth hormone (GH) on brain regeneration after an injury are well known. This paper looks at a male child diagnosed with cerebral palsy, psychomotor affectation, left spastic hemiparesis, and bilateral sensorineural hearing loss after fetal distress due to ruptured membranes before the delivery of more than 30 hours of evolution and several episodes of severe hypoglycemia. From 3.5 months of age, we treated him with GH (0.04 mg/kg/day), Melatonin (5 mg/day and 6 months later 10 mg/day) and rehabilitation, for a period of 14 months; at discharge, the child fully recovered all the disabilities produced by his cerebral palsy, including normal hearing; GMFM-88 increased from 7.84% to 48.23%; Battelle scores increased from 2 to 9 after 7 months of treatment, and to 30, 1 year after discharge. Most likely hearing loss was recovered due to the effect of GH on the production of hair cells from stem cells (only present in very young children) in the cochlear sensory epithelium. This is the first case of recovery of hearing loss in humans after GH administration. Moreover, GH administration is useful and safe for early treatment of cerebral palsy. View Full-Text
Keywords: hearing loss; cerebral palsy; growth hormone; auditory stimulation; physiotherapy hearing loss; cerebral palsy; growth hormone; auditory stimulation; physiotherapy
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Guerra, J.; Devesa, A.; Llorente, D.; Mouro, R.; Alonso, A.; García-Cancela, J.; Devesa, J. Early Treatment with Growth Hormone (GH) and Rehabilitation Recovers Hearing in a Child with Cerebral Palsy. Reports 2019, 2, 4.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Reports EISSN 2571-841X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top