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Neuroglia 2018, 1(1), 245-257;

An Early History of Neuroglial Research: Personalities

Scimed Biotechnologies, s.r.o., 25241 Zlatníky-Hodkovice, Czech Republic
Institute of Pharmacology and Toxicology, Faculty of Medicine in Plzeň, Charles University, 30605 Plzeň, Czech Republic
Faculty of Biology, Medicine and Health, The University of Manchester, M13 9PT Manchester, UK
Achucarro Center for Neuroscience, IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain
Center for Basic and Translational Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark
Authors to whom correspondence should be addressed.
Received: 16 July 2018 / Revised: 31 July 2018 / Accepted: 6 August 2018 / Published: 16 August 2018
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Neuroscience, like most other divisions of natural philosophy, emerged in the Hellenistic world following the first experimental discoveries of the nerves connecting the brain with the body. The first fundamental doctrine on brain function highlighted the role for a specific substance, pneuma, which appeared as a substrate for brain function and, being transported through the hollow nerves, operated the peripheral organs. A paradigm shift occurred in 17th century when brain function was relocated to the grey matter. Beginning from the end of the 18th century, the existence of active and passive portions of the nervous tissue were postulated. The passive part of the nervous tissue has been further conceptualised by Rudolf Virchow, who introduced the notion of neuroglia as a connective tissue of the brain and the spinal cord. During the second half of the 19th century, the cellular architecture of the brain was been extensively studied, which led to an in-depth morphological characterisation of multiple cell types, including a detailed description of the neuroglia. Here, we present the views and discoveries of the main personalities of early neuroglial research. View Full-Text
Keywords: neuroglia; neuroscience; history; glial research neuroglia; neuroscience; history; glial research

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Chvátal, A.; Verkhratsky, A. An Early History of Neuroglial Research: Personalities. Neuroglia 2018, 1, 245-257.

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