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Review

The Rise of Foundation Models: Opportunities, Technology, Applications, Challenges, Recent Trends, and Future Directions

1
Institute of Digital Anti-Aging Healthcare, Inje University, Gimhae 50834, Republic of Korea
2
Interdisciplinary Research Center for Intelligent Manufacturing and Robotics, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Appl. Syst. Innov. 2026, 9(2), 35; https://doi.org/10.3390/asi9020035
Submission received: 29 October 2025 / Revised: 20 November 2025 / Accepted: 5 January 2026 / Published: 30 January 2026

Abstract

Foundation models (FMs) have become a paradigm shift in the field of artificial intelligence, allowing one large-scale pretrained model to be customized for a broad set of downstream tasks using very little task-specific data. These models, which include GPT, CLIP, BERT, and vision transformers, have altered the scope of transfer learning and multimodal understanding and are built on top of enormous datasets and self-supervised learning. The paper provides a broad view of the modern state of foundation models, with an emphasis on their technological foundation, training, and cross-domain use in fields like natural language processing, computer vision, healthcare, robotics and scientific discovery. We also explore the main opportunities that FMs offer, as well as state-of-the-art methods and techniques for the development of foundation models. we discuss their applications in natural language processing, computer vision, healthcare, etc. Furthermore, their limitations and challenges are also investigated. Lastly, future prospects are discussed so that professionals and scientists obtain a better understanding of the importance of foundation models for addressing their research goals.
Keywords: foundation models; LLMS; GPT; self-supervised learning; computer vision; transformers foundation models; LLMS; GPT; self-supervised learning; computer vision; transformers

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MDPI and ACS Style

Hussain, A.; Farwa, U.E.; Ali, S.; Kim, H.-C. The Rise of Foundation Models: Opportunities, Technology, Applications, Challenges, Recent Trends, and Future Directions. Appl. Syst. Innov. 2026, 9, 35. https://doi.org/10.3390/asi9020035

AMA Style

Hussain A, Farwa UE, Ali S, Kim H-C. The Rise of Foundation Models: Opportunities, Technology, Applications, Challenges, Recent Trends, and Future Directions. Applied System Innovation. 2026; 9(2):35. https://doi.org/10.3390/asi9020035

Chicago/Turabian Style

Hussain, Ali, Umm E Farwa, Sikandar Ali, and Hee-Cheol Kim. 2026. "The Rise of Foundation Models: Opportunities, Technology, Applications, Challenges, Recent Trends, and Future Directions" Applied System Innovation 9, no. 2: 35. https://doi.org/10.3390/asi9020035

APA Style

Hussain, A., Farwa, U. E., Ali, S., & Kim, H.-C. (2026). The Rise of Foundation Models: Opportunities, Technology, Applications, Challenges, Recent Trends, and Future Directions. Applied System Innovation, 9(2), 35. https://doi.org/10.3390/asi9020035

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