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Volume 85
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10.5603/ARM.a2017.0045
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Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.
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Review

Eosinophilic COPD―A Distinct Phenotype of the Disease

by
Damian Tworek
* and
Adam Antczak
Department of General and Oncological Pulmonology, Medical University of Lodz, Kopcinskiego 22, 90-153 Lodz, Poland
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2017, 85(5), 271-276; https://doi.org/10.5603/ARM.a2017.0045
Submission received: 11 July 2017 / Revised: 1 August 2017 / Accepted: 1 August 2017 / Published: 30 October 2017

Abstract

Chronic Obstructive Pulmonary Disease (COPD) has been traditionally associated with neutrophilic inflammation of the bronchi. Studies from the early 1990s demonstrated that eosinophils may also migrate into the lower airways of patients with COPD and their increased numbers can be noticed during exacerbations as well as stable disease. Eosinophilic phenotype of COPD is characterized by several unique features, i.e., a specific pattern of airway inflammation and distinct clinical course or susceptibility to corticosteroid treatment. In this paper, we present an up-to-date review of the literature on clinical characteristics of eosinophilic COPD, as well as the role of eosinophils as a biomarker-guided therapy in COPD.
Keywords: COPD; eosinophils; biomarkers COPD; eosinophils; biomarkers

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MDPI and ACS Style

Tworek, D.; Antczak, A. Eosinophilic COPD―A Distinct Phenotype of the Disease. Adv. Respir. Med. 2017, 85, 271-276. https://doi.org/10.5603/ARM.a2017.0045

AMA Style

Tworek D, Antczak A. Eosinophilic COPD―A Distinct Phenotype of the Disease. Advances in Respiratory Medicine. 2017; 85(5):271-276. https://doi.org/10.5603/ARM.a2017.0045

Chicago/Turabian Style

Tworek, Damian, and Adam Antczak. 2017. "Eosinophilic COPD―A Distinct Phenotype of the Disease" Advances in Respiratory Medicine 85, no. 5: 271-276. https://doi.org/10.5603/ARM.a2017.0045

APA Style

Tworek, D., & Antczak, A. (2017). Eosinophilic COPD―A Distinct Phenotype of the Disease. Advances in Respiratory Medicine, 85(5), 271-276. https://doi.org/10.5603/ARM.a2017.0045

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