Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD

Maskey-Warzęchowska, Marta; Przybyłowski, Tadeusz; Hildebrand, Katarzyna; Wrotek, Katarzyna; Wiwała, Joanna; Kościuch, Justyna; Chazan, Ryszarda

doi:10.5603/ARM.28075

Open AccessArticle

Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD

by

Marta Maskey-Warzęchowska

^*,

Tadeusz Przybyłowski

,

Katarzyna Hildebrand

,

Katarzyna Wrotek

,

Joanna Wiwała

,

Justyna Kościuch

and

Ryszarda Chazan

Katedra i Klinika Chorób Wewnętrznych, Pneumonologii i Alergologii AM w Warszawie, Warsaw, Poland

^*

Author to whom correspondence should be addressed.

Adv. Respir. Med. 2006, 74(1), 72-76; https://doi.org/10.5603/ARM.28075

Submission received: 1 March 2006 / Revised: 1 March 2006 / Accepted: 1 March 2006 / Published: 1 March 2006

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Abstract

Many authors reported respiratory muscle function impairment in patients with chronic obstructive pulmonary disease (COPD). Impaired respiratory muscle function may contribute exercise intolerance which is frequently observed in this disease. Aim of the study: was to determine the influence of respiratory muscle function on exercise capacity in patients with COPD. Methods: 23 patients with stable COPD aged 62.7 ± 9.3 years (6F, 17M; mean post-bronchodilator FEV₁ = 47.9 ± 12.4% value predicted) participated in the study. Exercise capacity was assessed by the six-minute walk test and the incremental cardiopulmonary exercise test (CPET) on a treadmill. Maximal respiratory pressures (PI_max, PE_max) were evaluated before and directly after CPET. Results: The mean peak oxygen uptake (VO₂max) was 27.2 ± 6.1 mlO₂/min/kg and the mean distance walked during the 6 MWT was 569.4 ± 101.7 m. Both PImax and PEmax decreased significantly after maximal exercise (71.4 ± 23.0 vs. 63.6 ± 22.2 cm H₂O, p = 0.001 and 124.9 ± 46.5 vs. 112.3 ± 46.6 cm H₂O, p = 0.02 respectively). No correlation between VO₂max and the 6-minute walk distance and the maximal respiratory pressures was found. We observed a negative correlation between the 6-minute walk distance and the difference between the pre- and post CPET maximal inspiratory pressure. Conclusions: respiratory muscle function is impaired in patients with COPD but this does not affect exercise performance. Exercise causes a decrease of the respiratory muscle strength.

Keywords: COPD; respiratory muscles; respiratory pressures; exercise test

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MDPI and ACS Style

Maskey-Warzęchowska, M.; Przybyłowski, T.; Hildebrand, K.; Wrotek, K.; Wiwała, J.; Kościuch, J.; Chazan, R. Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD. Adv. Respir. Med. 2006, 74, 72-76. https://doi.org/10.5603/ARM.28075

AMA Style

Maskey-Warzęchowska M, Przybyłowski T, Hildebrand K, Wrotek K, Wiwała J, Kościuch J, Chazan R. Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD. Advances in Respiratory Medicine. 2006; 74(1):72-76. https://doi.org/10.5603/ARM.28075

Chicago/Turabian Style

Maskey-Warzęchowska, Marta, Tadeusz Przybyłowski, Katarzyna Hildebrand, Katarzyna Wrotek, Joanna Wiwała, Justyna Kościuch, and Ryszarda Chazan. 2006. "Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD" Advances in Respiratory Medicine 74, no. 1: 72-76. https://doi.org/10.5603/ARM.28075

APA Style

Maskey-Warzęchowska, M., Przybyłowski, T., Hildebrand, K., Wrotek, K., Wiwała, J., Kościuch, J., & Chazan, R. (2006). Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD. Advances in Respiratory Medicine, 74(1), 72-76. https://doi.org/10.5603/ARM.28075

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Maximal Respiratory Pressures and Exercise Tolerance in Patients with COPD

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