Preparation of Colloidal Silver Triangular Nanoplates and Their Application in SERS Detection of Trace Levels of Antibiotic Enrofloxacin
Round 1
Reviewer 1 Report
Comments and Suggestions for AuthorsThe paper discussed the synthesis of silver triangular nanoplates designed for use as SERS substrates for the detection of enrofloxacin. The study tackled the foundation in terms of evaluating the substrate in its capability of detecting target analytes. All necessary information has been provided but I have the following questions/suggestions:
1. As with the limit of detection, it was stated that it was found to be 10-13 M. Although the spectra of R6G at varying concentrations were provided, I suggest that it is better to also include spectra at concentrations lower than 10-13 M just to show that 10-13 M is indeed the lowest concentration in which signals are still detectable.
2. I also suggest that you make a table of the characteristic peak assignments with the corresponding reference(s) as it is more organized and easier to look up than finding for the assignments in the main text.
3. I would also like to ask why the peak at 1390 cm-1 was chosen as the reference peak in coming up with the regression equation? I think it is better to include a brief explanation in the manuscript with the reason why this peak was chosen. Likewise, why was the peak at 1511 cm-1 was chosen in the calculation of the EF? Most of published works choose the peak at 1361 cm-1 in the calculation of the EF so I'm curious to know why you chose 1511 cm-1.
My suggestions are only minor and considering these suggestions and addressing my questions can somehow improve the content of the manuscript. Overall, the article was straightforward and easy to understand and there is no need for any major revisions.
Author Response
We sincerely thank the reviewer for your thoughtful and constructive comments, which have greatly helped us improve the clarity, depth, and rigor of our work.
A detailed response to each of the reviewer’s comments has been provided in the attached file, which also includes supporting images for clarity.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Comments and Suggestions for AuthorsThe comments are listed in the attachment file.
Comments for author File: Comments.pdf
Author Response
We sincerely thank the reviewer for your thoughtful and constructive comments, which have greatly helped us improve the clarity, depth, and rigor of our work.
A detailed response to each of the reviewer’s comments has been provided in the attached file, which also includes supporting images for clarity.
Author Response File: Author Response.pdf
Round 2
Reviewer 2 Report
Comments and Suggestions for Authorsaccept
Author Response
The authors would like to express their sincere gratitude to the reviewer for their kind acceptance and valuable feedback.
On behalf of all the authors,
Luong Truc-Quynh Ngan
