The Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazol-4-carbonitrile with beta-Cycloketols†
Department of Chemistry and High Technologies, Kuban State University, 149 Stavropolskaya str, Krasnodar 350040, Russia
ChemEx Lab, Vladimir Dal’ Lugansk National University, 20A/7 Molodezhny, Lugansk 91034, Russia
Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., 355009 Stavropol, Russia
North Caucasus Humanitarian Technological Academy, Medical Institute, 36 Stavropolskaya str., 369000 Cherkessk, Russia
The Federal State Unitary Enterprise “Institute of Chemical Reagents and High Purity Chemical Substances” of National Research Centre “Kurchatov Institute”, 3 Bogorodsky Val, Moscow 107076, Russia
Author to whom correspondence should be addressed.
Presented at the 22nd International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2018; Available Online: https://sciforum.net/conference/ecsoc-22
Published: 14 November 2018
PDF [361 KB, uploaded 20 March 2019]
Abstract The reaction of 5-amino-3-(cyanomethyl)-1H-pyrazole-4-carbonitrile with 3-aryl-2,4-di (ethoxycarbonyl)-5-hydroxy-5-methylcyclohexanones in boiling acetic acid leads to the formation of new 4,5,6,7,8,9-hexahydropyrazolo[1,5-a]quinazolines. The mechanism is discussed. The structure of the products was confirmed by means of 1Н и 13С (DEPTQ) NMR, as well as 2D NMR (NOESY, 1Н–13С HSQC, HMBC).
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Dotsenko, V.V.; Semenova, A.M.; Chigorina, E.A.; Aksenov, N.A.; Aksenova, I.V. The Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazol-4-carbonitrile with beta-Cycloketols. Proceedings 2019, 9, 25.
Dotsenko VV, Semenova AM, Chigorina EA, Aksenov NA, Aksenova IV. The Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazol-4-carbonitrile with beta-Cycloketols. Proceedings. 2019; 9(1):25.
Dotsenko, Victor V.; Semenova, Aminat M.; Chigorina, Elena A.; Aksenov, Nikolai A.; Aksenova, Inna V. 2019. "The Reaction of 5-Amino-3-(cyanomethyl)-1H-pyrazol-4-carbonitrile with beta-Cycloketols." Proceedings 9, no. 1: 25.
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