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Proceedings 2018, 2(13), 947; https://doi.org/10.3390/proceedings2130947

A549 Cells Measurements with Optical, Impedance and Microwave Spectroscopy

1
Animalia AS, Norwegian Meat Research Institute, 0513 Oslo, Norway
2
Faculty of Science and Technology, Norwegian University of Life Sciences, 1432 Ås, Norway
3
Faculty of Engineering and Technology, Liverpool John Moores University, Liverpool L3 3AF, UK
4
Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK
Presented at the Eurosensors 2018 Conference, Graz, Austria, 9–12 September 2018.
*
Author to whom correspondence should be addressed.
Published: 7 December 2018
PDF [729 KB, uploaded 7 December 2018]

Abstract

Lung cancer, especially lung adenocarcinoma, is one of the main causes of death worldwide. This paper reports on the real-time detection methods of human lung adenocarcinoma A549 cells. The proposed approach is based on using optical, impedance and microwave spectroscopy in an attempt to develop an online tool that can be easily used for early cancer diagnostics and treatment monitoring not only in the hospital labs, but at point of care. Low power athermal electromagnetic waves as a sensing mechanism for early cancer detection showed a particular promise. The techniques were also applied to other cells, such as PC3, LL24, HLF, HACAT and DU145, to ensure selectivity of the sensors. Providing real-time information at point of care will be a significant leap on its own as it will dramatically increase screening capabilities.
Keywords: microwave spectroscopy; cancer cells detection; A549; optical and electrical properties; point of care monitoring microwave spectroscopy; cancer cells detection; A549; optical and electrical properties; point of care monitoring
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Mason, A.; Bryan, N.; Korostynska, O. A549 Cells Measurements with Optical, Impedance and Microwave Spectroscopy. Proceedings 2018, 2, 947.

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