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Abstract

Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial †

by
Alayne L. M. Pereira
1,*,
Silvana S. Funghetto
1,
Marina M. Stival
1,
Giovana Alcântara
2,
Izabel R. Silva
1,
Aline F. Oliveira
1,
Yuri G. S. Barbalho
1 and
Raíza R. De S. L. Trombini
1
1
Graduate Program in Health Sciences and Technologies, Faculty of Health Sciences and Technologies, University of Brasília, Brasília 70910-900, Brazil
2
Undergraduate Course in Nursing, University of Brasília, Brasília 70910-900, Brazil
*
Author to whom correspondence should be addressed.
Presented at the 6th International Congress on Health Innovation—INOVATEC 2025, Hybrid, 21–23 November 2025.
Proceedings 2026, 137(1), 99; https://doi.org/10.3390/proceedings2026137099
Published: 4 March 2026
(This article belongs to the Proceedings of The 6th International Congress on Health Innovation—INOVATEC 2025)
Keywords: hypertension; medication adherence; mobile applications
Introduction: Adherence to antihypertensive treatment is a major challenge in managing Systemic Arterial Hypertension (SAH) among the elderly. Digital health technologies such as mobile applications offer promising tools to support therapeutic adherence and self-care. This study aimed to evaluate the effectiveness of a mobile application in improving adherence to antihypertensive treatment in elderly individuals. Methodology: A randomized, parallel, double-blind clinical trial was conducted with 50 participants aged ≥60 years diagnosed with stage 1 or 2 SAH. Participants were allocated to a control group (CG), which received an educational booklet, or an intervention group (IG), which used the “Bem Lembrado” app for three months. Adherence was assessed using the MMAS-8 scale and self-care with the EAC-HI scale, and clinical and biochemical parameters were also measured. Results: The intervention group showed a significant improvement in treatment adherence (p < 0.05), with an increased proportion of adherent patients post-intervention. Improvements were also observed in self-care scores, blood pressure levels, and biochemical markers compared to the control group. The study is registered with the Brazilian Clinical Trials Registry (REBEC) platform, under registration RBR-6kw6qnx, and the research was carried out with the consent of the institutions (UnB and FEPECS) in which data collection was carried out. It was approved by the Research Ethics Committee of the University of Brasília, Faculty of Ceilândia, according to opinion number 5.637.553 and CAAE 62700422.0.0000.8093. Conclusions: The use of mobile health technologies can be an effective strategy to enhance adherence to antihypertensive treatment in elderly populations, promoting autonomy and better disease control.

Author Contributions

Conceptualization, A.L.M.P. and S.S.F.; methodology, A.L.M.P.; G.A.; A.F.O. and S.S.F.; validation, A.L.M.P.; G.A.; A.F.O.; Y.G.S.B.; R.R.D.S.L.T.; I.R.S. and S.S.F.; formal analysis, A.L.M.P. and S.S.F.; investigation, A.L.M.P. and S.S.F.; data curation, A.L.M.P. and S.S.F.; writing—original draft preparation, A.L.M.P. and S.S.F.; writing—review and editing, A.L.M.P. and S.S.F.; visualization, S.S.F.; supervision, S.S.F. and M.M.S.; project administration, A.L.M.P., S.S.F. and M.M.S.; funding acquisition, S.S.F. All authors have read and agreed to the published version of the manuscript.

Funding

This research was funded by the Fundação de Apoio à Pesquisa do Distrito Federal (FAP-DF), process nº 00193000000780/2021-74, and Rede Geronto.

Institutional Review Board Statement

The study is registered on the Brazilian Registry of Clinical Trials (REBEC) platform, under the title “Therapeutic Adherence in Elderly People with Arterial Hypertension: a randomized clinical trial”, number: RBR-6kw6qnx This study was approved by the Research Ethics Committee of the University of Brasília, Ceilândia Faculty, according to opinion number: 5.637.553 and CAAE: 62700422.0.0000.8093.

Informed Consent Statement

Informed consent was obtained from all subjects involved in the study.

Data Availability Statement

The data presented in this study are available upon request from the corresponding author.

Conflicts of Interest

The authors declare no conflict of interest.
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Share and Cite

MDPI and ACS Style

Pereira, A.L.M.; Funghetto, S.S.; Stival, M.M.; Alcântara, G.; Silva, I.R.; Oliveira, A.F.; Barbalho, Y.G.S.; Trombini, R.R.D.S.L. Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial. Proceedings 2026, 137, 99. https://doi.org/10.3390/proceedings2026137099

AMA Style

Pereira ALM, Funghetto SS, Stival MM, Alcântara G, Silva IR, Oliveira AF, Barbalho YGS, Trombini RRDSL. Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial. Proceedings. 2026; 137(1):99. https://doi.org/10.3390/proceedings2026137099

Chicago/Turabian Style

Pereira, Alayne L. M., Silvana S. Funghetto, Marina M. Stival, Giovana Alcântara, Izabel R. Silva, Aline F. Oliveira, Yuri G. S. Barbalho, and Raíza R. De S. L. Trombini. 2026. "Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial" Proceedings 137, no. 1: 99. https://doi.org/10.3390/proceedings2026137099

APA Style

Pereira, A. L. M., Funghetto, S. S., Stival, M. M., Alcântara, G., Silva, I. R., Oliveira, A. F., Barbalho, Y. G. S., & Trombini, R. R. D. S. L. (2026). Mobile App Improves Adherence to Antihypertensive Treatment in Elderly People with Hypertension: A Randomized Clinical Trial. Proceedings, 137(1), 99. https://doi.org/10.3390/proceedings2026137099

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