Surface Modification of Diamond for Sensor Applications †
1
M. Hinz UG (haftungsbeschraenkt), Floriansbogen 2-4, 82061 Neuried, Germany
2
Division of Experimental Anesthesiology, University Hospital Ulm, 89077 Ulm, Germany
*
Authors to whom correspondence should be addressed.
†
Presented at the 5th International Symposium on Sensor Science (I3S 2017), Barcelona, Spain, 27–29 September 2017.
Proceedings 2017, 1(8), 743; https://doi.org/10.3390/proceedings1080743
Published: 30 November 2017
(This article belongs to the Proceedings of Proceedings of the 5th International Symposium on Sensor Science (I3S 2017))
Diamond is a very interesting material for sensor applications: it has a high bio-compatibility which makes it interesting for in-vivo applications and in the form of boron-doped diamond it is a p-type semiconductor which makes diamond potentially useful in electrochemical sensor applications.
Even so diamond can be synthesized with relative ease as bulk material or in the form of (structured) films (CVD-diamond), it is not as common as e.g., gold in sensor applications. This may in part be due to the impression, that diamond is not easily modified with hapten or detection molecules. In reality the surface chemistry of diamond is versatile and rather easily accessible by classical wet chemical methods.
As an example, the introduction of hydroxy-groups by oxidation/reduction of nanodiamond and the subsequent modification with an activated double bond was carried out. Using the double bond to immobilize an amino modified oligonucleotide, a system for detection of miRNAs in living cells, based on fluorescence quenching, was assembled on nanodiamond.
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MDPI and ACS Style
Hinz, M.; Schneider, M. Surface Modification of Diamond for Sensor Applications. Proceedings 2017, 1, 743. https://doi.org/10.3390/proceedings1080743
AMA Style
Hinz M, Schneider M. Surface Modification of Diamond for Sensor Applications. Proceedings. 2017; 1(8):743. https://doi.org/10.3390/proceedings1080743
Chicago/Turabian StyleHinz, Michael, and Marion Schneider. 2017. "Surface Modification of Diamond for Sensor Applications" Proceedings 1, no. 8: 743. https://doi.org/10.3390/proceedings1080743
