Abstract
In this paper, we study the traveling wave solution of an epidemic model with mixed diffusion. First, we give two definitions of the minimum wave speeds and prove that they are equivalent. Second, the existence, decaying behavior, and uniqueness of traveling wave fronts are obtained. Third, the signs of minimum wave speeds are studied, and further, in two specific cases of the dispersal kernel, we show how to identify the signs of minimum wave speeds.
1. Introduction
This paper is devoted to studying the following epidemic model:
where and in biology stand for the spatial concentration of an infectious agent and the spatial density of the infectious human population, respectively; and denote the natural death rates of the infectious agent and infectious humans; means the growth of the infectious agent caused by infectious humans; and is the infection rate of the human population under the assumption that the total susceptible human population is a constant during the evolution of the epidemic. The model (1) describes a positive feedback interaction between the concentration of infectious agent and the infectious human population; that is, a high concentration of infectious agent leads to a large infection rate in the human population, and as more people are infected, the growth rate of the infectious agent increases. This model is an extension to the classical SEIR (susceptible–exposed–infectious–recovered) model. There is a widely adopted numerical approach to the solution of epidemic phenomena based on the modification of SEIR model and similar ones, and the very recent contributions include [,,].
The model (1) is a mixed-diffusion variant of the following classical epidemic model:
which was proposed by Capasso and Maddalena [,] to model the spread of cholera in the European Mediterranean regions in 1973. In (2), the diffusions of infectious agent and infectious human are described by the classical diffusion operators and . However, in (1), the diffusion of infectious human is represented by the nonlocal dispersal operator
where can be viewed as the probability of individuals moving from location y to location x (see []). Compared to the classical diffusion operator, the nonlocal dispersal operator describes the movements between not only adjacent but also nonadjacent spatial locations. Here the nonlocal dispersal of v can be thought as the long-distance movements of infectious humans across cites or countries by air traffic and other long-distance transportation. If the diffusion of infectious agent is also nonlocal, then (1) reduces to the following nonlocal dispersal model:
In (3), the nonlocal dispersal operator means that long-distance movements of infectious agent happen; for example, the infectious agent can move among countries through the transportation of imported food or the flow of international rivers.
The wave propagation phenomena, which are associated with the studies of traveling wave solutions and spreading speeds of systems (2) and (3), have been widely studied in the literature. For example, Hsu and Yang [] considered the existence, uniqueness, and decaying behavior of traveling wave fronts of (2), and Wu and Hsu [] studied the entire solutions of (2). We also refer to [,] for the traveling wave solution of (2) in the case , and [,] for traveling wave solutions of a more general system that includes (2) as a special case. For the nonlocal dispersal model (3), we assume that satisfies for . Li, Xu, and Zhang []; and Meng, Yu, and Hsu [] studied the traveling wave solutions and entire solutions. We also refer to [,] for the traveling wave solutions and spreading speed of (3) in the case . The spreading speed of (3) was studied by Bao et al. [], Hu et al. [], and Xu et al. [].
The study of the following scalar dispersal equation with reaction:
is also closely related to (1) and (3), where is a dispersal operator. There are various forms of , such as classical diffusion , nonlocal dispersal , fractional Laplacian (see [] for a recent review), and variable-order Riemann–Liouville fractional derivatives defined by [,]
where is the gamma function. The variability and transition of fractional orders contribute to the detailed description of highly heterogeneous systems and complex phenomena. Such scenarios have motivated the formulation of variable-order fractional operators and related algorithms—for example, []. Consider the monostable case with f satisfying the following Fisher–KPP condition
The different forms of usually cause distinct wave propagation phenomena of (4).
- (i)
- When , (4) is a classical reaction-diffusion equation and there is a unique traveling wave front for any speed , but no traveling wave solution for the speed .
- (ii)
- When , (4) is a fractional diffusion equation with reaction, and there is no traveling wave solution for any speed . Moreover, it was shown that the front position propagates exponentially; see, e.g., [,,]. To the best of our knowledge, there is no result about the propagation dynamics of variable-order fractional diffusion equations, and our work could possibly provide some basis for this topic.
For the case , the properties of K determine whether (4) admits a traveling wave front spreading at a finite speed or has exponentially propagating front position. More precisely, when the symmetric kernel K satisfies for , there exists such that (4) has a unique traveling wave front for any speed , and no traveling wave solution with the speed ; see [,,,,,,]. However, when K is “heavy-tailed”, in the sense that as , there is no traveling wave solution for any speed and the spatial propagation of front position is accelerated; see, e.g., [,,,]. In particular, when as , the front position propagates exponentially, which means the nonlocal dispersal case with an algebraic-tailed kernel has similar wave propagation properties to the case .
To the best of our knowledge, there is no result about the traveling wave solutions of the mixed-diffusion model (1), although its background in biology is clear; that is, the movements of an infectious agent are local, but the long-distance movements of infectious human happen. Herein, we consider the traveling wave solutions and the minimum wave speeds in monostable system (1). A traveling wave solution of (1) is a solution of the special form , which can be regarded as the dispersal process of epidemic from outbreak to an endemic. Usually, a non-decreasing or non-increasing traveling wave solution is called a traveling wave front. Note that we use the form to represent not only non-increasing but also non-decreasing traveling wave front. Therefore, no matter whether a traveling wave solution is non-increasing or non-decreasing, when its speed is positive, it propagates from left to right along the x-axis, and when its speed is negative, it propagates from right to left on the x-axis. In this paper, we study the “light-tailed” dispersal kernel, namely, , for . Our results can be summarized from three angles.
First, we give two definitions of the minimum wave speeds. The first definition is related to the principal eigenvalue of a linear operator derived from (1), and this definition is common in the study of traveling wave solutions and spreading speeds in (2) and (3), and other related systems (see, e.g., [,,,,]). The second definition is related to the root number of an eigenvalue equation, and this definition is used to study the traveling wave solutions in [,]. Moreover, we prove that these two definitions are equivalent.
Second, we consider the traveling wave solutions of (1). Motivated by the works of [,,,], we change the traveling wave solution problem into investigating the fixed point of a nonlinear operator, and the existence of traveling wave front is obtained by constructing a pair of upper and lower solutions and applying the Schauder’s fixed point theorem. The decaying behavior and uniqueness of traveling wave fronts are also obtained.
Third, we study the signs of minimum wave speeds. In (1), the kernel function is assumed to be asymmetric. As stated in [], asymmetric kernels may induce non-positive minimal wave speed. Thus, it is significant to study the signs of minimum wave speeds, which determine whether it happens that the asymmetric kernel changes the propagation direction of traveling wave solutions. Motivated by the work of [] for (3), we show that the signs of minimum wave speeds of (1) depend only on the number of elements in some set, which is further applied to two specific forms of (i.e., normal distribution and uniform distribution). For these two specific forms, the study of signs of minimum wave speeds is quite different from that considered in [] for (3), because in this work for (1) we consider the influences of the asymmetric dispersal of v under the assumption that u has symmetric local diffusion, but in [] for (3), the authors study the influences of symmetric nonlocal kernel of v when u has asymmetric nonlocal dispersal. We show that when is normal distribution or uniform distribution, the signs of minimum wave speeds depend only on and where is the expectation and is the variance of K, which is different from the results obtained in [] for (3). Thus, the study for the cases of normal distribution and uniform distribution in this paper is a new result to understand the influences of asymmetric dispersal on the signs of minimum wave speeds.
The rest of this paper is organized as follows. In Section 2, we give two definitions of minimum wave speeds and prove they are equivalent. Section 3 presents the existence, uniqueness, and decaying behavior of traveling wave fronts of (1). Section 4 deals with the signs of minimum wave speeds, and the results for two specific forms of K are given.
2. Two Definitions of Minimum Wave Speeds
In the section, we give two definitions of minimum wave speeds and prove that they are equivalent. First we state the assumptions. Assume that
- (A1)
- and are two functions in with and , and , , for ;
- (A2)
- , for ; , for .
Then (1) is a monostable system with equilibria and , and there exists no equilibrium satisfying . We can easily check that for , which implies that
We assume that is a continuous and nonnegative function satisfying
- (K)
- , for , and there exist and such that and .
Note that we do not assume that is symmetric.
2.1. The First Definition
We denote
Consider the matrix
Let be the large one of the two eigenvalues of , namely,
and then . Denote
It follows that
Theorem 1.
We have the following statements about :
- (i)
- satisfies that
- (ii)
- There are two unique constants and such that
- (iii)
- If we setthen holds.
Proof.
Since and , we get from that
which implies that and . Note that
and then
Similarly, it holds that .
The proofs of (ii) and (iii) are similar to the counterpart in the proof of [] (Theorem 2.1). □
2.2. The Second Definition
Consider the function
where
We can easily check that
and
Then, there exist four unique constants and such that
and
Denote
and it follows that .
Theorem 2.
For sufficiently large , has exactly three different positive roots and one negative root. For sufficiently small , has exactly three different negative roots and one positive root.
Proof.
We have that
Since
then has a unique root in and a unique root in . In or , since , we have that , which implies that has no root in or .
Next consider the roots in . Note that
Then
We can easily check that
Therefore, for sufficiently large , has at least one root in and at least one root in . Similarly, for sufficiently small , has at least one root in and at least one root in .
We now prove that has at most two roots in . When belongs to and satisfies
we have that since and , which along with and , implies that
Then the function has only a unique maximum point and no minimum point in . By Rolle’s theorem, we can obtain the existence of maximum point of in , which is denoted by . Moreover, we have that for , and for . Therefore, has at most two roots in , which (if exist) are in and , respectively.
Therefore, for sufficiently large , has exactly three different positive roots and one negative root. For sufficiently small , has exactly three different negative roots and one positive root. □
Definition 1.
From Theorem 2, we can define
Let
A simple calculation implies
Since and for , we have that for , and for . Since with is strictly increasing in c, the proof of Theorem 2 implies that the root number of in is non-decreasing in c. Definition 1 shows that
Similarly, we have that
2.3. Equivalence of Two Definitions
Theorem 3.
and .
Proof.
First, we prove . For any , Theorem 1 implies that there are two positive constants and such that
From (6), it follows that
which mean that
Then and are two different positive roots of , and for any . From (7) it follows that .
Second, we prove . For any , by the proof of Theorem 2 and Definition 1, has two different positive roots in , and we denote them by and with . Then for , we have that
where , and
It follows that
Note that if , then
which is a contradiction. Thus, we have that
which implies that
We obtain .
Therefore, it holds that , and the proof of is similar. □
Theorem 3 shows that the first definition for and in Theorem 1 (iii) is equivalent to the second definition for and in Definition 1. Thus, we use and for the minimum wave speeds in the rest of the paper.
3. Traveling Wave Solutions
In this section, we consider the traveling wave solutions of (1). First, we introduce the notations for the standard order in . For and , we denote if and ; if but ; and if and .
Substituting into (1) and letting , we can get that
Let , . For a non-increasing traveling wave front, we assume the boundary condition
and for a non-decreasing traveling wave front, we assume the boundary condition
Define satisfying
where and are the roots of the equation , namely,
Note that satisfies that
Therefore, a fixed point of F is a solution of (9).
Definition 2.
Next we consider the non-increasing traveling wave front satisfying (10). Define
The following result reduces the existence of the solution of (9) to the existence of a pair of upper and lower solutions satisfying some additional conditions.
Theorem 4.
Assume that , , and hold. If (9) has an upper solution and a lower solution satisfying
- (a)
- for any ,
- (b)
- (9) has no constant solution on ,
- (c)
- for ,
- (d)
- for ,
Proof.
The proof is similar to the proofs of [] (Theorem 2.2) and [] (Theorem 3.2), where Schauder’s fixed point theorem is applied to obtain the fixed point of F. The properties for can be studied by the method in [] (Lemmas 2.3 and 2.4). The properties for can be obtained from [] (Lemmas 3.3, 3.5, 3.6, and 3.7). Thus, we omit the details. □
By Theorem 4, we can obtain the following results of traveling wave fronts.
Theorem 5.
Proof.
We consider the existence of a non-increasing traveling wave front satisfying (10) and the existence of a non-decreasing traveling wave front satisfying (11) to be similar. By Theorem 2 and Definition 1, when , there are two different positive roots of in , and we denote them by and with . Define
Consider satisfying
where is the constant in (A1). We define
where q is a sufficiently large constant, and satisfies
By the methods in [] (Lemma 2.7) and [] (Lemma 2.2), we can get that is an upper solution and is a lower solution of (1). Note that is non-increasing and for any . Then we have
which implies the condition (a) in Theorem 4 holds. Recall that there is no equilibrium of (1) satisfying , and then the condition (b) holds. The conditions (c) and (d) can be easily checked. By Theorem 4, (1) has a non-increasing traveling wave front with satisfying (10).
Now we consider the case . Let satisfy and as . Then there is a sequence of non-increasing continuous functions satisfying
By the methods in the proof of [] (Theorem 1.1), the function sequences , , and are uniformly bounded and equicontinuous on ; and by the methods in the proof of [] (Theorem 2.1), the function sequences and are uniformly bounded and equicontinuous on . By the Arzela–Ascoli theorem, we can find a subsequence of denoted by such that
From (13), it follows that
Then is a traveling wave front of (1) with satisfying (10).
Finally, the proof of the nonexistence of traveling wave solution with is similar to the counterpart in [] (Theorem 2.1) or [] (Theorem 1.1). □
By Theorem 2 and Definition 1, when , has three positive roots, and let be the smallest one. When , has three negative roots, and let be the largest one. Define
Now suppose that . It follows that . By a similar argument for in the proof of Theorem 2, there are two positive roots and two negative roots of . Let be the larger negative root, and let be the smaller positive root. The following two theorems study the decaying behavior and uniqueness of traveling wave fronts.
Theorem 6.
Theorem 7.
The proof of Theorem 6 is similar to Theorem 2.2 in [], and we give a scheme here. By a similar argument for (27) in [], there are two constants and such that
Define
Multiplying (9) by and integrating it over , we obtain that
where
It follows that
If and are monotonous, we can get (14) and (15) by Ikehara’s theorem. If not, define for . When p is large enough, and are monotonous since and are bounded. Then we can get (14) and (15) by applying Ikehara’s theorem to and . The result (16) can be similarly proved by considering as . The proofs of (17), (18), and (19) are similar to (14), (15), and (16), respectively.
The proof of Theorem 7 is based on the following claim: if on , then either or on , where and are two solutions of (9) with (10) or (11). If there exists satisfying , since is a maximum point of , we have that
It follows from and that and for any , which implies that for (by redefining and repeating this process if ). By the uniqueness of solution for the equation with , we get for . Hence, it holds that on . If there exists satisfying , we have that
It follows from and that , which implies that on by the argument above. The claim is proved, and Theorem 7 is proved by a similar method to Theorem 1.2 in [].
4. The Signs of Minimum Wave Speeds
In this section, we show how to identify the signs of and . Recall that
Define
Theorem 8.
We have that either or , and
- (i)
- ;
- (ii)
- is a singleton set;
- (iii)
- ;
- (iv)
- is a singleton set;
- (v)
- .
Proof.
The proofs of “⇐” in (i)–(v) are similar to the proof of [] (Theorem 2.2). Now we prove “⇒” for (i)–(v). By Theorem 1, we get . Then the relationships among 0, , and in (i)–(v) are all possible cases. By [] (Theorem 2.2), is an empty set or a closed interval without 0 in . Then, either or . We have that the conditions of in (i)–(v) contain all possible cases, which means that must satisfy one of the conditions in (i)–(v). Therefore, the proofs of “⇒” can be obtained from “⇐” for (i)–(v). □
Next we give two specific forms of the kernel function . For each case, we show how to apply Theorem 8 to identify the signs of and .
4.1. Normal Distribution
Assume that satisfies that
Let . When , can be regarded as a function with parameters and r, namely,
Define
Corollary 1.
For any fixed r satisfying , there is a constant such that
- (i)
- the propagation to left fails, namely, ;
- (ii)
- ;
- (iii)
- the propagation to both left and right happens, namely, ;
- (iv)
- ;
- (v)
- the propagation to right fails, namely, .
Moreover, we have that where
For any r satisfying , it holds that for any .
Proof.
We first consider the case . Note that when , it holds that and . Now we consider the case , and the case can be obtained similarly. Some calculations imply that
Define
It follows that . For , since
the proof of [] (Theorem 2.2) shows that for .
When and , we have that
Define
From (20) and (21), it follows that
It is easy to check that
Then there is such that , which implies that for .
When and , we have that
which implies that
When , we can get that
It follows that
Then we have that , which implies
Consider a function which is from to the set that consists of all closed intervals in . We can check that
It follows that
and this inclusion is strict when .
Note that we have already obtained when . Now consider the case . For fixed r satisfying , it holds that as . Since , there exists sufficiently small such that
It follows that
Note that . Since , we have that is increasing in and for . Note that for , and then
We get that is an empty set for sufficiently small . Therefore, there exists such that
Considering and , we get by a similar argument as above that
By Theorem 8, we have proved “⇒” for (i)–(v) in Corollary 1. Note that the relationships among 0, , and in (i)–(v) are all possible cases; and the relationships among , , and in (i)–(v) are also all possible cases. Thus, the proofs of “⇐” can be obtained from “⇒” for (i)–(v).
Next, consider the case . When , it is easy to check that
which implies . When and , since
it holds that
In the above inequality, the equality holds only if , which implies . Then, when , we have that
which implies . □
4.2. Uniform Distribution
Suppose that is given by
where the constants and stand for the farthest distances of the movements of infectious agents during a unit time period to the right and left of x-axis, respectively. Some calculations imply that
Next, we state the following lemma whose proof can be found in [] (Lemma 5.3).
Lemma 1.
Define , . There is a unique non-zero continuous function from to with such that for any . Moreover, when ,
and when ,
We also have that is strictly increasing in , and when . Then it holds that for .
Denote , and let be the constant defined in Lemma 1. It follows from Lemma 1 that
and
When , it holds that and we denote
When , since , we can simply denote .
We denote
which implies that when , and . When (i.e., ), can be regarded as a function with parameters and r, namely,
Note that depends only on r and is independent of .
Corollary 2.
All results in Corollary 1 hold for the uniform distribution case after the definition of is replaced by
Proof.
Although the proof uses the idea similar to the proof of Corollary 1, we still give some details because some important calculations are different. When , recall that and , which imply that
Since for , we have that
which implies that when , namely, .
When we only consider the case (i.e., ), and the case (i.e., ) is similar. It holds that
For , since
we have that for .
When and , we have that
Denote
Then
By (23) and (24), we have that and . Thus, it holds that
Then, , which implies that for .
When and , we have that
and then
When , we have that by (23). When , it holds that
It follows that
Thus, for . Let be the function from to the set that consists of all closed intervals in . Note that
Then, we have
When , we have that , which implies along with Lemma 1 and that
It follows that
Then,
and this inclusion is strict when .
Some calculations show that
Since , there exists sufficiently small such that
By (24), is increasing in . We have that
Then, for sufficiently small. The rest of the proof is similar to the counterpart in the proof of Corollary 1. □
Remark 1.
Note that the parameter r for the normal distribution in Section 4.1 is defined by , where σ is variance and μ is expectation. For the uniform distribution, the variance of K is , and the expectation is . Consider
Since the function from to is bijection and increasing, we can use in place of r in Corollary 2. From the results in Section 4.1 and Section 4.2, we see that (or with some coefficient) and μ are important parameters to describe whether an asymmetric kernel changes the signs of minimum wave speeds.
5. Conclusions
We studied traveling wave solutions of an epidemic model with mixed diffusion. We gave two definitions of the minimum wave speeds, and the equivalence of these two definitions was proved. The existence, decaying behavior, and uniqueness of traveling wave fronts were obtained. We also presented how to identify the signs of minimum wave speeds and apply them to two specific forms of the kernel function, namely, normal distribution and uniform distribution. Our study indicates that in these two scenarios, the asymmetric nonlocal kernel may induce non-positive minimal wave speed and standing wave solution whose wave speed is zero. However, for general dispersal kernel with the expectation and the variance , it is unknown whether the parameters and can determine the signs of minimum wave speeds, and this interesting question will be the topic of future research.
Author Contributions
Conceptualization and formal analysis, W.-B.X.; validation and writing, R.H. All authors have read and agreed to the published version of the manuscript.
Funding
This research of R. Hou was funded by China Postdoctoral Science Foundation, grant number BX20200011.
Institutional Review Board Statement
Not applicable.
Informed Consent Statement
Not applicable.
Data Availability Statement
Not applicable.
Conflicts of Interest
The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
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