Integration of Lean Analytics and Industry 6.0: A Novel Meta-Theoretical Framework for Antifragile, Generative AI-Orchestrated, Circular–Regenerative, and Hyper-Connected Manufacturing Ecosystems
Abstract
1. Introduction
- Antifragile Lean Systems Theory: Extends Lean’s focus from stability and robustness to antifragility, providing models for systems that gain strength from disorder.
- GAI-Orchestrated Value Streams: Shifts the analytical focus from human-driven optimization to the management and optimization of autonomous, GAI-driven value stream orchestration.
- Circular–Regenerative Analytics: Integrates circular economy and regenerative design principles into the core of Lean performance measurement, moving beyond simple sustainability metrics.
- Hyper-Connected Ecosystem Integration: Provides analytical tools for optimizing information flow and performance across vast, interconnected virtual–physical ecosystems.
2. The Path to I6.0
2.1. I4.0: The Digital Foundation
2.2. The “Digital to Cybernized” Leap
2.3. I5.0: The Human-Centric and Resilient Correction
- Human–Robot Collaboration: A shift from full automation [14] to a collaborative model where humans and robots (cobots) work together, leveraging the unique strengths of each.
- Personalization and Customization: A focus on meeting the individual needs of customers [15], moving away from mass production towards mass personalization.
- Sustainability and Resilience: A greater emphasis on resource efficiency [16], circular economy principles, and building resilient supply chains capable of withstanding global disruptions.
2.4. I6.0: The Autonomous, Antifragile, and Regenerative Future
2.4.1. The Shift to Autonomy: Generative AI Orchestration
2.4.2. The Shift to Antifragility
2.4.3. The Shift to Deep Sustainability: Circular and Regenerative Systems
2.4.4. The Shift to Hyper-Connected Ecosystems
3. Research Gap Analysis: The Obsolescence of Current Lean Analytics
3.1. The Inadequacy of “Robustness” in an Antifragile World
3.2. The Shift from Human-Driven to GAI-Driven Optimization
- Value Stream Mapping (VSM): A team of people walks the Gemba, observes the process, and manually draws a map [34].
- A3 Problem Solving: A structured, collaborative problem-solving process guided by a human mentor [35].
- Kaizen Events: A focused, week-long event where a cross-functional team works to improve a specific process [36].
3.3. The Superficiality of “Green Lean”
3.4. The Bounded Nature of Current Analytics
4. Mathematical Modeling of the I6LA Framework
4.1. Pillar 1: Antifragile Lean Systems Theory
- From Waste Elimination to Optionality Creation: Traditional Lean focuses on eliminating the seven wastes (muda) to create a streamlined, efficient process. Antifragile Lean complements this by prioritizing the creation of optionality. This means building systems with strategic redundancy, modular product and process architectures, and multiple sourcing strategies. While these might appear as “waste” from a traditional Lean perspective (e.g., excess inventory, underutilized capacity), they are re-framed as valuable options that allow the system to adapt and thrive in the face of unexpected events. The analytical challenge is to distinguish between “bad” waste and “good” optionality.
- Stress-Induced Continuous Improvement: The Lean principle of Kaizen (continuous improvement) is re-imagined. Instead of relying solely on planned improvement events, Antifragile Lean treats disruptions (e.g., supply chain delays, demand spikes, equipment failures) as opportunities for learning and adaptation. The framework includes mechanisms for “stress testing” the system with controlled disruptions and using the resulting data to drive system evolution. This is a more dynamic and event-driven form of continuous improvement.
- Barbell Asymmetry in Risk and Innovation Management Strategy in Manufacturing: This principle provides a practical approach to managing risk and innovation. It involves allocating the majority of resources (e.g., 90%) to highly reliable, efficient, and low-risk processes (the “safe” bar). The remaining resources (e.g., 10%) are invested in high-risk, high-reward experimental processes, such as testing novel materials or radical new production methods (the “speculative” bar). This strategy allows the system to benefit from massive upside potential from innovation while being protected from catastrophic failure (risk).
4.1.1. Antifragility Index (AFI)
- Demand shock: ;
- Supply disruption: ;
- Equipment failure: .
- AFI > 0: The system is antifragile. It improved as a result of the stressor.
- AFI = 0: The system is robust. It was unaffected by the stressor.
- AFI < 0: The system is fragile. Its performance degraded as a result of the stressor.
4.1.2. AFI Severity Normalization
4.2. Pillar 2: Generative AI-Orchestrated Value Streams
- Intent-Based Management: This represents a radical departure from traditional management. Human managers no longer design detailed workflows or make tactical decisions. Instead, they define high-level strategic intent in natural language (e.g., “prioritize customer X’s order while maintaining a 95% sustainability score and keeping costs below Y”). The GAI orchestrator then autonomously generates, executes, and optimizes the detailed workflow to achieve that intent. The role of the human manager shifts from micro-manager to strategic director and ethicist.
- Emergent Value Stream Mapping (E-VSM): Traditional VSM is a static snapshot of a human-designed process. It is unsuitable for analyzing a process that is constantly changing and adapting. The I6LA framework introduces E-VSM, a new analytical tool where AI is used to visualize and analyze the dynamic, constantly evolving value streams created by the GAI orchestrator in real-time. E-VSM would use techniques from process mining and graph theory to identify emergent bottlenecks, waste, and opportunities for improvement in the AI-driven process.
- The “Digital Gemba” and the Principle of Genchi Genbutsu: The core Lean principle of Genchi Genbutsu (“go and see for yourself”) is adapted for the digital age. The Digital Gemba is a virtual environment (e.g., a sophisticated digital twin) where managers can observe, analyze, and interact with the GAI-driven processes in real-time. This allows them to gain a deep understanding of how the AI is making decisions and to identify areas where the AI’s behavior may be misaligned with strategic intent, without having to understand the underlying code.
4.2.1. Generative Orchestration Efficiency (GOE)
Factors Impacting GOE Calculation
4.2.2. Data Handling
4.3. Pillar 3: Circular–Regenerative Analytics
- The “10 Rs” of Lean: The traditional “3Rs” of sustainability (Reduce, Reuse, Recycle) are expanded to a more comprehensive set of circular economy principles, which are treated as core Lean objectives. These include Refuse, Rethink, Reduce, Reuse, Repair, Refurbish, Remanufacture, Repurpose, Recycle, and Recover. The I6LA Framework provides metrics for each of these “10 Rs,” allowing them to be integrated into a holistic measure of circularity (see Figure 8).
- Real-Time Life Cycle Assessment (LCA): Traditional LCA is a time-consuming, offline process. The I6LA framework proposes the use of digital twins and real-time data from IoT sensors to perform LCA dynamically, as products are being designed and manufactured. This would allow the GAI orchestrator to make real-time trade-offs between production efficiency and life cycle impact, for example, by choosing a slightly more expensive but more easily recyclable material.
- Value Stream Mapping for Circularity (VSM-C): A new form of VSM is proposed that maps not just the flow of materials and information in the forward supply chain, but also the reverse loops of the circular economy. VSM-C would visualize the flow of used products, components, and materials back into the production system, identifying wastes and opportunities in the reverse logistics, remanufacturing, and recycling processes.
4.3.1. Circularity Integration Score (CIS)
Mathematical Impact
4.4. Pillar 4: Hyper-Connected Ecosystem Integration
- Ecosystem-Level Kaizen: The concept of Kaizen is applied to the entire ecosystem. The framework includes mechanisms for identifying and eliminating “ecosystem wastes” such as information asymmetry between partners, data friction at system interfaces, misaligned incentives, and delays caused by a lack of trust. This requires a new level of inter-organizational collaboration and data sharing.
- The “Metaverse Gemba”: Building on the Digital Gemba, the Metaverse Gemba is a shared, persistent virtual space where all stakeholders in the ecosystem (e.g., suppliers, logistics providers, customers, maintenance partners) can interact with a live digital twin of the entire value network. This enables a new form of collaborative problem-solving, where a supplier in one country can work with an engineer in another to diagnose and fix a problem in a factory in a third country, all within a shared virtual environment.
- Information Flow as a Utility: The framework treats information flow not as a series of discrete transactions, but as a continuous, utility-like service that must be optimized for quality, latency, security, and cost across the entire ecosystem. This requires a new set of metrics and analytical tools focused on the health and performance of the underlying data fabric that connects the ecosystem.
Ecosystem Connectivity Index (ECI)
- : end-to-end latency (seconds).
- : usable throughput (bits/s or messages/s).
- : availability (fraction of time link meets minimum service).
- : packet/message success probability (1—loss/error rate).
- : security score (compliance/assurance, including access control and policy enforcement).
- : semantic interoperability score (schema/ontology alignment; automated meaning-preserving exchange).
- : marginal service cost (e.g., $ per GB or per message).
- : digital twin coverage fraction (fraction of nodes with an active, live twin).
- : synchronization quality score, derived from synchronization lag.
- : stakeholder participation fraction (fraction of nodes that actively interact with the shared environment during ).
- : collaborative resolution rate (fraction of cross-node incidents resolved via collaborative sessions within a target time).
4.5. Adaptive Lean Performance (ALP)
4.6. Hyperparameter Selection and Interpretation
5. Implementation, Validation, Implication, and Comparisons
5.1. Implementation Methodology
5.1.1. Phase 1: Ecosystem Assessment and Baseline Measurement
- Stakeholder Mapping and Strategic Alignment: Identify all principal stakeholders within the ecosystem (internal departments, suppliers, partners, customers) and facilitate workshops to achieve consensus on the strategic objectives for the I6LA transformation.
- Current State VSM: Perform an exhaustive Value Stream Mapping of both the tangible material flow and the digital information flow. This should encompass not only the industrial premises but also critical suppliers and distribution networks.
- Data and Technology Audit: Perform a thorough audit of the existing data sources, systems, and technology infrastructure. The goal is to identify data silos, integration challenges, and gaps in the technology stack required for I6.0.
- Baseline Performance Measurement: Establish baseline measurements for various measures, encompassing classic Lean KPIs (OEE, FTT, lead time, inventory turns) and initial estimations for I6LA indicators where feasible (e.g., a qualitative evaluation of fragility, a tentative CIS derived from current recycling programs).
- Baseline Performance Report: A comprehensive document detailing the current performance of the manufacturing system.
- Ecosystem Map: A visual representation of the key stakeholders, processes, and information flows in the ecosystem.
- Technology and Data Gap Analysis: A report identifying the specific gaps in the current technology stack and data infrastructure that need to be addressed.
5.1.2. Phase 2: Foundational Technology and Framework Design
- GAI orchestrator pilot deployment: Choose and implement a pilot version of a GAI orchestrator. This may entail collaborating with a technology vendor or cultivating an internal capacity. The primary emphasis is on a restricted, non-essential procedure.
- Digital twin and data fabric development: Commence the creation of a high-fidelity digital twin of the industrial ecosystem. This entails constructing the foundational data fabric, APIs, and integration interfaces to provide real-time data transmission from all pertinent sources.
- I6LA model customization: Customize the mathematical models of the I6LA Framework (AFI, GOE, CIS, ECI, ALP) for the specific context of the organization. This involves defining the specific variables, data sources, and weighting factors for each model.
- Deployed GAI pilot: A functional pilot of the GAI orchestrator, operating in a sandbox environment.
- Digital twin: The initial iteration of the ecosystem digital twin, proficient in real-time visualization of the current situation.
- I6LA metrics specification document: A comprehensive paper outlining the calculation and application of each I6LA statistic within the organization.
5.1.3. Phase 3: Pilot Implementation and Calibration
- Select a pilot value stream: Choose a value stream that is complex enough to be meaningful but not so critical that failure would be catastrophic.
- Deploy I6LA analytics: Implement the full suite of I6LA analytics for the pilot value stream, providing real-time data on the I6LA metrics via dashboards and the “Digital Gemba”.
- Train a pilot team: Train a cross-functional team of human managers on the principles of Intent-Based Management and how to use the new analytical tools.
- Calibrate and refine models: Use the real-world data from the pilot to calibrate and refine the I6LA mathematical models. This includes running controlled stress tests to measure and improve the AFI.
- Pilot performance report: A detailed report on the performance of the pilot value stream, comparing the I6LA metrics with the baseline measurements.
- Calibrated I6LA models: A fully calibrated and validated set of I6LA models for the pilot area.
- Lessons learned document and playbook: A comprehensive document capturing the key learnings from the pilot, which will serve as a playbook for the scaled rollout.
5.1.4. Phase 4: Scaled Rollout and Continuous Evolution (Ongoing)
- Develop a phased rollout plan: Based on the learnings from the pilot, develop a detailed plan for rolling out the I6LA framework to other value streams and business units.
- Establish a governance model: Create a clear governance model for the GAI orchestrator, defining the roles and responsibilities of human managers, the rules of engagement for the AI, and the ethical guardrails within which it must operate.
- Scale technology and training: Scale the deployment of the digital twin, data fabric, and other enabling technologies. Roll out training programs on I6LA principles and tools across the organization.
- Create a continuous feedback loop: Establish a formal process for continuously monitoring the performance of the I6LA framework, gathering feedback from users, and using that feedback to refine the models, tools, and processes.
- Enterprise-wide I6LA dashboard: A real-time dashboard providing a holistic view of the organization’s performance according to the I6LA metrics.
- GAI governance charter: A formal document outlining the governance model for the GAI orchestrator.
- Quarterly evolution reports: Regular reports on the performance of the I6LA Framework and the progress of the ongoing evolution.
5.1.5. Proposed Preliminary Modeling
5.1.6. Data Workflow and Model Construction
5.1.7. Suggested Workflow of Data Processing Pipeline
5.2. Validation Framework
5.2.1. Quantitative Validation
- Longitudinal tracking of I6LA metrics: The primary method of quantitative validation is the longitudinal tracking of the five core I6LA metrics (AFI, GOE, CIS, ECI, ALP). A successful implementation should demonstrate a statistically significant positive trend in these metrics over time.
- Correlation with business KPIs: The I6LA metrics should be correlated with traditional business KPIs such as Return on Investment (ROI), profit margin, market share, and customer satisfaction. This is to ensure that the improvements measured by the I6LA framework are translating into tangible business value.
- Controlled experiments and A/B testing: Where possible, controlled experiments can be conducted to compare the performance of a value stream managed according to I6LA principles with a similar value stream managed using traditional methods. This can provide strong evidence for the framework’s effectiveness.
5.2.2. Qualitative Validation
- Case studies: In-depth case studies of specific improvement initiatives driven by the I6LA framework can provide rich, contextualized evidence of its impact. These case studies should document the problem, the I6LA-driven solution, and the results.
- Semi-structured interviews: Interviews with human managers, engineers, and operators can provide valuable insights into their experience with the new paradigm of Intent-Based Management, the Digital/Metaverse Gemba, and collaboration with the GAI orchestrator.
- Ethnographic observation: Ethnographic studies of how work and decision-making patterns change after the implementation of the I6LA framework can reveal subtle but important shifts in organizational culture and capabilities.
5.2.3. Simulation-Based Validation
- “What-If” scenario analysis: The digital twin can be used to run “what-if” scenarios to test the framework’s response to a wide range of potential disruptions, from supply chain shocks to cyberattacks to sudden shifts in customer demand [98]. This allows for the validation of the system’s antifragility in a safe, controlled environment.
- Validation of GAI behavior: The digital twin can be used to validate the GAI orchestrator’s decision-making. Its proposed strategies can be tested in simulation and compared against the decisions of human experts in the same scenarios.
- Long-term forecasting: Simulation can be used to forecast the long-term impact of I6LA-driven strategies on ecosystem stability, sustainability, and performance, allowing for the exploration of potential second- and third-order effects that might not be immediately apparent.
5.3. Simulation
Sensitivity Analysis
5.4. Discussion and Implications
5.4.1. Theoretical Implications
- A Paradigm Shift for Lean: The framework fundamentally extends the Lean philosophy, moving it from a focus on efficiency and waste elimination in stable systems to a new paradigm of managing complex, adaptive, and autonomous ecosystems. It redefines core Lean concepts like Kaizen, Gemba, and VSM for the I6.0 era, ensuring the continued relevance of Lean thinking in a radically different technological and operational context.
- Operationalizing Antifragility: While the concept of antifragility has been influential in fields like finance and software engineering, its application to manufacturing has been largely metaphorical. The I6LA framework, through the AFI and the principle of Stress-Induced Continuous Improvement, provides one of the first concrete, quantifiable methods for operationalizing antifragility in a manufacturing context.
- A Framework for AI-Driven Management: The I6LA framework provides a new theoretical lens for understanding and managing organizations where key operational decisions are made by autonomous AI agents. The concepts of the GOE metric offer a new vocabulary and a new set of tools for the emerging field of AI-driven management.
- Integrating Sustainability into Core Operations: The framework moves beyond the peripheral “Green Lean” initiatives by integrating circular and regenerative principles into the core analytical engine of the manufacturing system. The CIS elevates sustainability from a reporting metric to a real-time operational variable, on par with cost and quality.
5.4.2. Practical Implications for Organizations
- A New Role for Human Workers: The framework envisions a significant evolution in the role of human workers in manufacturing. As GAI takes over the tactical and operational decision-making, the human role shifts to higher-level, more strategic tasks: defining intent, setting ethical boundaries, designing the ecosystem, and managing the relationship between the human and AI elements of the system. This requires a massive investment in reskilling and upskilling the workforce.
- A Shift in Organizational Structure: The traditional hierarchical, command-and-control organizational structure is ill-suited for the dynamic, decentralized nature of I6.0. The I6LA Framework implies a shift towards more agile, networked, and ecosystem-based organizational models, where collaboration and information sharing across organizational boundaries are the norm.
- A New Approach to Investment and ROI: The framework challenges traditional approaches to investment and ROI calculation. Investments in optionality and redundancy, which might appear wasteful from a traditional perspective, are reframed as essential for building antifragility. The ROI of a technology investment must be measured not just by its impact on efficiency, but also by its contribution to the AFI, GOE, CIS, and ECI.
- Data as a Core Asset: The I6LA Framework underscores the critical importance of data and information flow. It requires organizations to treat their data fabric as a core strategic asset, investing in the infrastructure, governance, and security needed to ensure the seamless and trustworthy flow of information across the entire ecosystem.
5.4.3. Challenges
- Technological Maturity: Many of the technologies required for a full implementation of the I6LA framework, such as true GAI orchestration, quantum computing, and metaverse-scale digital twins, are still in their infancy. The framework is, by necessity, forward-looking and its full realization will depend on the maturation rate of these technologies.
- Complexity of Measurement: The mathematical models proposed in this paper, while theoretically sound, will be challenging to implement in practice. The data requirements are immense, and the process of defining and calibrating the variables for each model will be a significant undertaking.
- Ethical and Governance Concerns: The shift to GAI-driven autonomy raises profound ethical and governance questions. How do we ensure that the GAI orchestrator makes decisions that are not only efficient but also ethical? How do we maintain human oversight and control over a system that is designed to be autonomous? These are complex questions that the framework acknowledges but does not fully resolve.
- Cultural Resistance: The transition to an I6LA-driven paradigm will likely face significant cultural resistance. The shift in the human role, the need for radical transparency and data sharing, and the embrace of volatility and uncertainty will all challenge long-held assumptions and ways of working.
5.4.4. Limitations
Latency Requirements
Hallucinations
5.5. Comparison with Related Theoretical Frameworks
5.5.1. Comparison with Complex Adaptive Systems (CAS) Theory
- Similarities: The I6LA framework shares some concepts with CAS theory. The vision of GAI-orchestrated value streams, with decentralized AI agents interacting and adapting, is fundamentally a CAS. The concept of emergent behavior, where system-level properties arise from the interactions of individual agents, is central to both frameworks.
- Differences: The I6LA framework is more prescriptive than CAS theory. While CAS theory provides a descriptive lens for understanding complex systems, the I6LA framework provides a normative framework for designing and managing such systems in a manufacturing context. The I6LA framework also introduces specific metrics (AFI, GOE, CIS, ECI, ALP) that are not part of general CAS theory.
5.5.2. Comparison with Socio-Technical Systems (STS) Theory
- Similarities: The I6LA framework is deeply aligned with STS theory. The emphasis on the changing role of human workers, the importance of trust in AI, and the need for a just transition are all consistent with STS principles.
- Differences: The I6LA framework extends STS theory to a new context: the relationship between humans and autonomous AI agents. Traditional STS theory focused on the relationship between humans and technology (e.g., machines, software). The I6LA framework addresses the more complex relationship between humans and AI systems that can learn, adapt, and make autonomous decisions.
5.5.3. Comparison with Industrial Ecology
- Similarities: The Circular–Regenerative Analytics pillar (Pillar 3) of the I6LA framework is directly informed by Industrial Ecology. The concepts of the circular economy, life cycle assessment, and material flow analysis are all central to both frameworks.
- Differences: The I6LA framework integrates Industrial Ecology concepts into a broader framework that also addresses antifragility, AI-driven autonomy, and ecosystem connectivity. It also emphasizes the real-time integration of sustainability metrics into operational decision-making, which goes beyond the traditional, offline approach of Industrial Ecology.
5.5.4. Comparison with the Theory of Constraints (TOC)
- Similarities: The I6LA framework shares TOC’s focus on system-level optimization. The concept of Emergent VSM, which identifies bottlenecks in GAI-orchestrated value streams, is analogous to TOC’s focus on identifying constraints.
- Differences: TOC was developed for relatively stable, human-managed systems. The I6LA framework extends this thinking to dynamic, autonomous systems where the constraints themselves may be constantly changing. The I6LA framework also has a broader scope, addressing not just throughput optimization, but also antifragility, sustainability, and ecosystem connectivity.
6. Conclusions and Future Research
- Empirical validation: The most critical next step is the empirical validation of the framework in real-world or highly realistic simulated manufacturing environments. This will involve implementing the I6LA metrics, testing their correlation with business performance, and refining the models based on real-world data.
- Development of sub-models: Each of the I6LA metrics requires further theoretical development. For example, future research could focus on developing more metric models, or on creating a detailed taxonomy of “ecosystem wastes” to support the ECI.
- Organizational and management theory: The I6LA framework calls for a new approach to management and organization. Future research in the fields of organizational behavior and management science is needed to develop the new theories and practices required to lead and work in an I6LA-driven enterprise.
- Ethical frameworks for GAI orchestration: A dedicated stream of research is needed to develop robust ethical frameworks and governance models for the GAI orchestrators that are at the heart of the I6LA paradigm.
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
| Symbol | Meaning | Units |
|---|---|---|
| j | Disruption (or injected test) event index, j = 1,…,N | dimensionless (index) |
| N | Number of events in the evaluation set | count |
| tj(start) | Start time of event j | time (same unit as timestamps) |
| tj(end) | End time of event j | time (same unit as timestamps) |
| P(t) | Chosen Lean performance signal over time (e.g., OEE, FTT, throughput) | depends on signal; typically a dimensionless ratio or rate |
| Tpre | Length of pre-event averaging window | time |
| Tpost | Length of post-event averaging window | time |
| Tlag | Adaptation lag between the event end and the post-window start | time |
| Pj(pre) | Time-average of P(t) over the pre-event window for event j | same as P(t) |
| Pj(post) | Time-average of P(t) over the post-event window for event j | same as P(t) |
| rj | Event performance response log-ratio ln(Pj(post)/Pj(pre)) | dimensionless |
| sj(raw) | Raw disruption severity for event j (natural units for the event type) | event-type dependent (e.g., %, days, hours) |
| sref(τj) | Positive reference severity scale for event type τj | same as sj(raw) |
| Sj | Normalized severity Sj = sj(raw)/sref(τj) | dimensionless |
| O(t) | Optionality stock state variable | dimensionless index |
| Oj(pre) | Pre-event average optionality for event j | dimensionless |
| Oj(post) | Post-event average optionality for event j | dimensionless |
| ΔOj | Optionality creation during/after event j: Oj(post) − Oj(pre) | dimensionless |
| C(t) | Effective available capacity (planning granularity) | units of capacity (e.g., units/time or tool-hours) |
| Q(t) | Required capacity (same granularity as C(t)) | same as C(t) |
| ρt | Redundancy ratio ρt = C(t)/Q(t) (bounded as defined) | dimensionless |
| ρmax | Cap on redundancy ratio treated as “strategic” | dimensionless |
| R(t) | Redundancy subscore derived from ρt and ρmax | dimensionless (0–1) |
| κ(t) | Coupling proxy used to quantify modularity | depends on proxy; treated as dimensionless after normalization |
| κref | Reference coupling level for κ(t) | same as κ(t) |
| Mmod(t) | Modularity subscore (denoted M(t) in AFI pillar text) | dimensionless (0–1) |
| pk(t) | Share of source k for a critical component (multi-sourcing shares) | dimensionless (fractions sum to 1) |
| K | Number of qualified sources used in diversity calculation | count |
| Ds(t) | Multi-sourcing diversity subscore (concentration-based) | dimensionless (0–1) |
| wR, wM, wD | Weights for redundancy, modularity, and diversity in optionality | dimensionless (sum to 1) |
| Tj(rec) | Recovery time for event j (first time P(t) recovers above threshold) | time |
| θ | Recovery threshold multiplier relative to pre-event performance | dimensionless |
| Lj | Learning-from-stress signal from recovery time change vs prior comparable event | dimensionless |
| ℓ | Downside loss random variable for barbell risk | loss units (e.g., cost, days, throughput loss) |
| q | Tail probability level used for VaR/CVaR | dimensionless (probability) |
| VaRφ(ℓ) | Value-at-risk of loss ℓ at level q | same as ℓ |
| CVaRφ(ℓ) | Conditional value-at-risk of loss ℓ at level q | same as ℓ |
| m | Experiment index in speculative bar, m = 1,…,M | dimensionless (index) |
| M | Number of speculative experiments (context-dependent; not the ALP metric vector) | count |
| rm(exp) | Log return (or return proxy) of experiment m | dimensionless (log-return) or return units as defined |
| U | Mean realized speculative upside across experiments | same as rm(exp) |
| α | Safe-bar resource fraction in barbell strategy | dimensionless (fraction) |
| ε | Small numerical constant to avoid division by zero/log(0) | dimensionless |
| B | Barbell asymmetry variable (upside relative to extreme downside exposure) | dimensionless |
| β0,…,β5 | Regression coefficients in event-level gain-per-stress model | units depend on regressor scaling; AFI itself is dimensionless |
| εj | Regression error term for event j | same as dependent variable rj/Sj (dimensionless) |
| xj, X, y, β | Regression covariate vector, design matrix, response vector, coefficient vector | dimensionless after normalization |
| S, Opre, ΔO, L | Sample means of Sj, Oj(pre), ΔOj, Lj used in AFI definition | dimensionless |
| AFI | Antifragility Index (fitted expected gain-per-stress under typical conditions) | dimensionless |
| i | Disruption instance index within type k (severity normalization) | dimensionless (index) |
| k | Disruption type index (taxonomy class) | dimensionless (index) |
| sik | Realized severity, for instance, i of type k | same axis as AFI stress term (e.g., normalized downtime) |
| srefk | Reference severity scale for type k (robust central tendency with uncertainty) | same as sik |
| Symbol | Meaning | Units |
|---|---|---|
| t | Decision epoch | dimensionless (index) |
| xt | Latent physical production state | state-dependent |
| yt | Observed telemetry | telemetry-dependent |
| at | Executed orchestration action | action-dependent |
| ωt | Exogenous uncertainty/disturbance | context-dependent |
| πφ | Orchestrator policy parameterized by θ | mapping (no physical unit) |
| θ | Orchestrator configuration parameters | parameter set |
| It | Natural-language intent string | text |
| t | Compiled intent tuple | structured object |
| Intent weight vector over objectives | dimensionless | |
| Vector of objective targets | objective-dependent | |
| Set of hard constraints | set | |
| gp(·) | Constraint function p | constraint-dependent |
| Forbidden-action set | set | |
| Π | Formal preference structure | structure |
| t | Realized KPI vector | KPI-dependent |
| di | Direction indicator for objective i | dimensionless |
| σi | Normalization scale | same units as objective i |
| vi | Normalized violation | dimensionless |
| (vi)+ | Positive-part violation | dimensionless |
| Lt | Weighted quadratic loss | dimensionless |
| St | Intent-satisfaction factor exp(−Lt) | dimensionless (0–1) |
| Σt | Stress-weighting factor on value rate | dimensionless (0–1) |
| fuv(t) | Directly-follows frequency u → v | count |
| Mean waiting-time weight for u → v | time | |
| THt | Throughput rate | cases/time |
| Completed cases in window | count | |
| Δ | Window length | time |
| ; | First/last timestamps of case c | time |
| CTt | Mean cycle time | time/case |
| WIPt | Work-in-process proxy | count |
| SCRAPt | Scrap metric | count or fraction |
| Vt | Intent-aligned value rate | value/time or composite/time |
| α1 … α4 | Coefficients mapping flow measures into Vt | scaling coefficients |
| Orchestration compute time | time | |
| Mt | Coordination/message load | count |
| Rt | Replanning rate/count | count |
| c1, c2, c3 | Cost coefficients | overhead units per respective unit |
| Jt | Plan-churn distance δ(Πt, Πt−1) | distance units (defined by δ) |
| λ | Churn penalty weight | overhead units per churn unit |
| δ(·,·) | Plan-distance function | distance units |
| Ht | Governance/human-intervention burden | count |
| Qt | Digital Gemba query/audit burden | count |
| κ1, κ2 | Gemba burden weights | overhead units per count |
| Orchestration overhead | overhead units | |
| Governance overhead | overhead units | |
| Total overhead cost | overhead units | |
| γ | Discount factor | dimensionless |
| GOE | Generative Orchestration Efficiency | dimensionless ratio |
| Symbol | Meaning | Units |
|---|---|---|
| CIS(t) | Circularity Integration Score | dimensionless (0–1) |
| SR(t), SL(t), SV(t), SG(t) | Component scores (10R, real-time LCA, VSM-C, regenerative surplus) | dimensionless (0–1) |
| wR, wL, wV, wG | Component weights | dimensionless (sum to 1) |
| ε | Stability constant | dimensionless |
| T | Evaluation horizon length | epochs or time (as implemented) |
| CIS(0:T) | Horizon-level discounted CIS | dimensionless |
| r | 10R strategy index | dimensionless (index) |
| p | Product family/SKU index | dimensionless (index) |
| Set of monitored products | set | |
| E(p,r,t) | Eligible units/mass for strategy r | count or mass |
| U(p,r,t) | Units/mass handled under strategy r | count or mass |
| δ | Nonzero denominator constant | same as denominator quantity |
| φ(p,r,t) | Product-level realization rate | dimensionless |
| ωp | Portfolio weight | dimensionless |
| φr(t) | Portfolio realization rate for strategy r | dimensionless |
| ρr | Strategy weights within 10R component | dimensionless |
| SR(raw,t) | Raw 10R score | dimensionless |
| F(p,r,t) | Feasibility indicator | dimensionless (0/1) |
| Mp(t) | Misallocation mass/volume proxy | count or mass |
| μ(t) | Misallocation rate proxy | dimensionless |
| ΠR(t) | Dominance/feasibility penalty | dimensionless (0–1) |
| SR(t) | Final 10R component | dimensionless (0–1) |
| c | Impact-category index | dimensionless (index) |
| j | Elementary flow index | dimensionless (index) |
| J | Number of elementary flows | count |
| C | Number of impact categories | count |
| ej(t) | Measured elementary flow j | flow units (e.g., kg, kWh) |
| CF(j,c) | Characterization factor | impact units per flow unit |
| Ic(t) | Dynamic impact in category c | category units (e.g., kg CO2-eq) |
| Iref,c; Ibest,c | Reference and best/target impacts | same as Ic(t) |
| sc(t) | Normalized impact score | dimensionless (0–1) |
| βc | Impact-category weights | dimensionless |
| SL(t) | Aggregated LCA component | dimensionless (0–1) |
| qim(t) | Material flow rate from node i to m | mass/time or count/time |
| Node set in value-network graph | set | |
| m | Manufacturing node identifier | identifier |
| Erev | Reverse-loop edge set | set |
| Qin(t), Qsec(t) | Inbound and secondary inbound flows | same as q |
| LCR(t) | Loop-closure rate Qsec/Qin | dimensionless |
| c (customer) | Customer node index (contextual) | identifier |
| Qret(t), Qusable(t) | Returned flow and usable reintegrated input | same as q |
| RY(t) | Reverse yield Qusable/Qret | dimensionless |
| RLT(t) | Reverse lead time | time |
| RLTref, RLTbest | Reference/target reverse lead time | time |
| RT(t) | Reverse-time score | dimensionless (0–1) |
| αLcR, αRy, αRT | VSM-C aggregation weights | dimensionless |
| SV(t) | VSM-C component | dimensionless (0–1) |
| gc(t) | Regenerative credit in category c | same as category units |
| NPc(t) | Net-positive surplus max{0, gc(t) − Ic(t)} | category units |
| Target net-positive surplus | category units | |
| uc(t) | Bounded surplus score | dimensionless (0–1) |
| SG(t) | Regenerative component | dimensionless (0–1) |
| Symbol | Meaning | Units |
|---|---|---|
| t = (, t) | Information-fabric graph at epoch t | graph object |
| Stakeholder node set | set/count | |
| n | Number of nodes | count |
| i, j | Node indices | dimensionless (indices) |
| Lij(t) | End-to-end latency | seconds |
| Bij(t) | Usable throughput | bits/s or messages/s |
| Aij(t) | Availability | dimensionless fraction |
| Pij(t) | Success probability | dimensionless probability |
| Σij(t) | Security score | dimensionless (0–1) |
| Iij(t) | Semantic interoperability score | dimensionless (0–1) |
| Kij(t) | Marginal service cost | $/GB or $/message |
| Lref, Bref, Kref | Reference scales | seconds; bits/s (or msg/s); $/GB (or $/msg) |
| uLij(t), uBij(t), uKij(t) | Normalized utilities (latency/throughput/cost) | dimensionless (0–1) |
| uAij(t), uPij(t), u^Σij(t), uIij(t) | Normalized utilities (availability/success/security/interoperability) | dimensionless (0–1) |
| αL, αB, αA, αP, α^Σ, αI, αK | Attribute weights in edge-utility aggregation | dimensionless (sum to 1) |
| Uij(t) | Edge utility | dimensionless (0–1) |
| wij(t) | Effective information-carrying capacity/edge weight | throughput units scaled by utility |
| SU(t) | Ecosystem information-utility score | dimensionless (0–1) |
| W(t) | Symmetrized effective-weight matrix | same as wij |
| di(t) | Node degree in the symmetrized weighted graph | same as wij |
| D(t) | Degree matrix diag(di) | same as wij |
| L(t) | Weighted Laplacian L = D − W | same as wij |
| λ2(t) | Algebraic connectivity (Fiedler value) | same as wij |
| Wtot(t) | Total undirected weight budget | same as wij |
| SC(t) | Normalized structural connectivity score | dimensionless (0–1) |
| ntwin(t) | Nodes with active live digital twin | count |
| Ccov(t) | Twin coverage fraction ntwin/n | dimensionless (0–1) |
| Δsync(t) | Synchronization lag | time |
| Δref | Reference lag scale | time |
| Csync(t) | Synchronization score exp(−Δsync/Δref) | dimensionless (0–1) |
| nactive(t) | Nodes actively participating | count |
| Cpart(t) | Participation fraction nactive/n | dimensionless (0–1) |
| Ninc(≤τ) | Incidents resolved within threshold τ | count |
| Ninc(t) | Total incidents observed | count |
| Cres(t) | Resolution fraction | dimensionless (0–1) |
| βcov, βsync, βpart, βres | Metaverse Gemba weights | dimensionless (sum to 1) |
| SM(t) | Metaverse/Digital-Gemba observability score | dimensionless (0–1) |
| p(i·,t), p(·,t) | Belief distributions used in divergence term | dimensionless probability vectors |
| A(t) | Information-asymmetry divergence magnitude | dimensionless |
| Aref | Reference scale for asymmetry normalization | dimensionless |
| SA(t) | Asymmetry health score exp(−A/Aref) | dimensionless (0–1) |
| Nman(t) | Manual interventions | count |
| Ntx(t) | Traceability transactions/records | count |
| Ft | Friction ratio Nman/max{Ntx,1} | dimensionless |
| Fref | Reference friction scale | dimensionless |
| SF(t) | Friction health score exp(−F/Fref) | dimensionless (0–1) |
| rtaui, rtauE | Local/ecosystem traces used in misalignment proxy | trace-dependent |
| Mmis(t) | Misalignment magnitude | dimensionless |
| Mref | Reference misalignment scale | dimensionless |
| SMis(t) | Misalignment health score exp(−Mmis/Mref) | dimensionless (0–1) |
| t | Query/task set for trust-delay waste | set |
| τapp,φ; τreφ,φ | Achieved/requested times | time |
| Dwaste(t) | Trust-delay waste proxy | time |
| Dref | Reference delay scale | time |
| SD(t) | Delay health score exp(−Dwaste/Dref) | dimensionless (0–1) |
| ηA, ηf, ηMis, ηD | Weights in the ecosystem waste score | dimensionless (sum to 1) |
| SW(t) | Ecosystem-waste reduction score | dimensionless (0–1) |
| Ωt | Waste potential −ln(SW(t)+ε) | dimensionless |
| ΔΩt | Change in waste potential | dimensionless |
| ΔΩref | Reference scale for Kaizen normalization | dimensionless |
| SK(t) | Kaizen rate-of-improvement score | dimensionless (0–1) |
| wc, wU, wM, wW, wK | Top-level ECI weights | dimensionless (sum to 1) |
| ECI(t) | Ecosystem Connectivity Index | dimensionless (bounded) |
| ECI(0:T) | Horizon-level discounted ECI | dimensionless |
| Symbol | Meaning | Units |
|---|---|---|
| i | Metric index in ALP aggregation, i = 1,…,k | dimensionless (index) |
| k | Number of metrics in ALP aggregation | count |
| Mi(t) | Raw value of metric i at epoch t | metric-dependent |
| gi(·) | Metric-specific monotone normalization transform | mapping |
| i(t) | Normalized metric value in [0,1] | dimensionless (0–1) |
| wi(t) | Weight on metric i | dimensionless |
| pi(t) | Intent-derived priority for metric i | dimensionless |
| β | Inverse-temperature parameter in softmax mapping | dimensionless |
| (t) (vector) | Raw softmax weight proposal | dimensionless |
| Δ(k − 1) | (k − 1)-simplex | set |
| KL(w ∥ w′) | KL divergence is used in regularized projection | dimensionless |
| λ | Smoothing coefficient in weight projection | dimensionless (implementation-scaled) |
| ρ | Exponential-moving-average update rate | dimensionless (0–1) |
| R | Maximum weight ratio (used in ρ selection) | dimensionless |
| Δp | Typical priority separation (used in ρ selection) | dimensionless |
| ALP(t) | Adaptive Lean Performance | dimensionless (bounded by construction) |
References
- Verma, A.; Prasad, V.K.; Kumari, A.; Bhattacharya, P.; Srivastava, G.; Fang, K.; Wang, W.; Gadekallu, T.R. Industry 6.0: Vision, technical landscape, and opportunities. Alex. Eng. J. 2025, 130, 139–174. [Google Scholar] [CrossRef] [Scilit]
- Majeed, H.; Iftikhar, T. Industry 6.0 and the Rise of Intelligent Automation in Manufacturing. In Intelligent Manufacturing in Industry 6.0: A Climate Resilience Approach; Majeed, H., Iftikhar, T., Eds.; Springer Nature: Cham, Switzerland, 2026; pp. 293–343. [Google Scholar] [CrossRef] [Scilit]
- Fernández-Miguel, A.; Ortíz-Marcos, S.; Jiménez-Calzado, M.; Fernández del Hoyo, A.P.; García-Muiña, F.E.; Settembre-Blundo, D. Toward the Theoretical Foundations of Industry 6.0: A Framework for AI-Driven Decentralized Manufacturing Control. Future Internet 2025, 17, 455. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Hosseinzadeh, A.; Chen, F.F. Generative artificial intelligence in manufacturing: Applications, case studies, and future directions for next-generation intelligent production systems. Int. J. Adv. Manuf. Technol. 2025, 141, 1159–1265. [Google Scholar] [CrossRef] [Scilit]
- Ahmad, T.; Zhu, H.; Zhang, D.; Tariq, R.; Bassam, A.; Ullah, F.; Alshamrani, S.S. Energetics Systems and artificial intelligence: Applications of industry 4.0. Energy Rep. 2022, 8, 334–361. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Chen, F.F.; Bouzary, H.; Krishnaiyer, K. Integration of Lean practices and Industry 4.0 technologies: Smart manufacturing for next-generation enterprises. Int. J. Adv. Manuf. Technol. 2020, 107, 2927–2936. [Google Scholar] [CrossRef] [Scilit]
- Berthelot, A.; Caron, E.; Jay, M.; Lefèvre, L. Estimating the environmental impact of Generative-AI services using an LCA-based methodology. Procedia CIRP 2024, 122, 707–712. [Google Scholar] [CrossRef] [Scilit]
- Keramati, F.; Mohammadi, H.R.; Shiran, G.R. Determining optimal location and size of PEV fast-charging stations in coupled transportation and power distribution networks considering power loss and traffic congestion. Sustain. Energy Grids Netw. 2024, 38, 101268. [Google Scholar] [CrossRef] [Scilit]
- Annanperä, E.; Jurmu, M.; Kaivo-oja, J.; Kettunen, P.; Knudsen, M.; Lauraéus, T.; Majava, J.; Porras, J. From Industry X to Industry 6.0: Antifragile Manufacturing for People, Planet, and Profit with Passion; Business Finland AIF White Paper; Allied ICT Finland (AIF): Oulu, Finland, 2021; Available online: https://cris.vtt.fi/en/publications/from-industry-x-to-industry-60-antifragile-manufacturing-for-peop/ (accessed on 13 January 2026).
- Gomaa, A.H. Transforming Manufacturing from Industry 4.0 to Industry 6.0: A Comprehensive Review, Gap Analysis, and Strategic Framework. Interdiscip. Syst. Glob. Manag. 2025, 1, 29–51. [Google Scholar] [CrossRef] [Scilit]
- Madsen, D.Ø.; Slåtten, K.; Berg, T. From Industry 4.0 to Industry 6.0: Tracing the Evolution of Industrial Paradigms Through the Lens of Management Fashion Theory. Systems 2025, 13, 387. [Google Scholar] [CrossRef] [Scilit]
- Akundi, A.; Euresti, D.; Luna, S.; Ankobiah, W.; Lopes, A.; Edinbarough, I. State of Industry 5.0—Analysis and Identification of Current Research Trends. Appl. Syst. Innov. 2022, 5, 27. [Google Scholar] [CrossRef] [Scilit]
- Chen, S.-C.; Chen, H.-M.; Chen, H.-K.; Li, C.-L. Multi-Objective Optimization in Industry 5.0: Human-Centric AI Integration for Sustainable and Intelligent Manufacturing. Processes 2024, 12, 2723. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Chen, F.F.; Maghanaki, M.; Hosseinzadeh, A.; Zand, N.; Khodadadi Koodiani, H. Improving the Concrete Crack Detection Process via a Hybrid Visual Transformer Algorithm. Sensors 2024, 24, 3247. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Shahin, M.; Chen, F.F.; Maghanaki, M.; Hosseinzadeh, A. Adapting the GPT engine for proactive customer insight extraction in product development. Manuf. Lett. 2024, 41, 1376–1385. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Hosseinzadeh, A.; Chen, F.F. AI-Enabled Sustainable Manufacturing: Intelligent Package Integrity Monitoring for Waste Reduction in Supply Chains. Electronics 2025, 14, 2824. [Google Scholar] [CrossRef] [Scilit]
- Adel, A. Future of industry 5.0 in society: Human-centric solutions, challenges and prospective research areas. J. Cloud Comput. 2022, 11, 40. [Google Scholar] [CrossRef] [Scilit]
- Duggal, A.S.; Malik, P.K.; Gehlot, A.; Singh, R.; Gaba, G.S.; Masud, M.; Al-Amri, J.F. A sequential roadmap to Industry 6.0: Exploring future manufacturing trends. IET Commun. 2022, 16, 521–531. [Google Scholar] [CrossRef] [Scilit]
- Badhoutiya, A.; Darokar, H.; Verma, R.P.; Saraswat, M.; Devaraj, S.; Raj, V.H.; Abdulhussain, Z.N. Regenerative Manufacturing: Crafting a Sustainable Future through Design and Production. E3S Web Conf. 2023, 453, 01038. [Google Scholar] [CrossRef] [Scilit]
- Chourasia, S.; Tyagi, A.; Pandey, S.M.; Walia, R.S.; Murtaza, Q. Sustainability of Industry 6.0 in Global Perspective: Benefits and Challenges. MAPAN 2022, 37, 443–452. [Google Scholar] [CrossRef] [Scilit]
- Lykov, A.; Cabrera, M.A.; Konenkov, M.; Serpiva, V.; Gbagbe, K.F.; Alabbas, A.; Fedoseev, A.; Moreno, L.; Khan, M.H.; Guo, Z.; et al. Industry 6.0: New Generation of Industry driven by Generative AI and Swarm of Heterogeneous Robots. arXiv 2024, arXiv:2409.10106. [Google Scholar] [CrossRef] [Scilit]
- Fernández-Miguel, A.; García-Muiña, F.E.; Settembre-Blundo, D.; Tarantino, S.C.; Riccardi, M.P. Exploring Systemic Sustainability in Manufacturing: Geoanthropology’s Strategic Lens Shaping Industry 6.0. Glob. J. Flex. Syst. Manag. 2024, 25, 579–600. [Google Scholar] [CrossRef] [Scilit]
- Ahmed, D. A Survey of Generative Models in Modern Manufacturing. Robot. Comput.-Integr. Manuf. 2023, 23, 641–660. Available online: https://ijaem.net/issue_dcp/Survey%20of%20Generative%20AI%20Use%20Cases%20in%20Manufacturing%20Industries.pdf (accessed on 13 January 2026).
- Becker, M.; Kasprowicz, D.; Kurkina, T.; Davari, M.D.; Gipperich, M.; Gramelsberger, G.; Bergs, T.; Schwaneberg, U.; Trauth, D. Toward Antifragile Manufacturing: Concepts from Nature and Complex Human-Made Systems to Gain from Stressors and Volatility. In Transformation Towards Sustainability: A Novel Interdisciplinary Framework from RWTH Aachen University; Letmathe, P., Roll, C., Balleer, A., Böschen, S., Breuer, W., Förster, A., Gramelsberger, G., Greiff, K., Häußling, R., Lemme, M., et al., Eds.; Springer International Publishing: Cham, Switzerland, 2024; pp. 425–448. [Google Scholar] [CrossRef] [Scilit]
- Chenaru, O.; Mocanu, S.; Dobrescu, R.; Nicolae, M. Enhancing Antifragile Performance of Manufacturing Systems through Predictive Maintenance. Appl. Sci. 2022, 12, 11958. [Google Scholar] [CrossRef] [Scilit]
- Roci, M.; Salehi, N.; Amir, S.; Shoaib-ul-Hasan, S.; Asif, F.M.A.; Mihelič, A.; Rashid, A. Towards circular manufacturing systems implementation: A complex adaptive systems perspective using modelling and simulation as a quantitative analysis tool. Sustain. Prod. Consum. 2022, 31, 97–112. [Google Scholar] [CrossRef] [Scilit]
- Konietzko, J.; Das, A.; Bocken, N. Towards regenerative business models: A necessary shift? Sustain. Prod. Consum. 2023, 38, 372–388. [Google Scholar] [CrossRef] [Scilit]
- Keramati, F.; Mohammadi, H.R. Optimal Placement of Plug-in Electric Vehicles Fast-Charging Stations Using Geographic Information System and Considering Power Distribution Network Indexes: A Case Study in Kabul. Int. J. Ind. Electron. Control Optim. 2024, 7, 313–325. [Google Scholar] [CrossRef]
- Zhang, H.; Sun, X.; Mynors, D.; Guo, C. Combining Virtual Reality with the Physical Model Factory: A Practice Course Designed for Manufacturing Process Education. Processes 2025, 13, 2946. [Google Scholar] [CrossRef] [Scilit]
- Hines, P.; Netland, T.H. Teaching a Lean masterclass in the metaverse. Int. J. Lean Six Sigma 2022, 14, 1121–1143. [Google Scholar] [CrossRef] [Scilit]
- Hung, Y.-H.; Li, L.Y.O.; Cheng, T.C.E. Uncovering hidden capacity in overall equipment effectiveness management. Int. J. Prod. Econ. 2022, 248, 108494. [Google Scholar] [CrossRef] [Scilit]
- Johannes, K.; Tatiana, B. Factors to achieve cost efficiency in operation and manufacturing projects in VUCA environment. IFAC-Pap. 2024, 58, 38–43. [Google Scholar] [CrossRef] [Scilit]
- Baran, B.E.; Woznyj, H.M. Managing VUCA: The human dynamics of agility. Organ. Dyn. 2021, 50, 100787. [Google Scholar] [CrossRef] [Scilit]
- Luiz Kyrillos, S.; João do Nascimento, R.; de Souza, J.B.; Ollitta Junior, U.; Benedito Saccomano, J. Value Stream Mapping (VSM) Applied to a Company of the Metal-Mechanic in 4.0 Industry Context. Rev. FSA 2021, 18, 18–36. [Google Scholar] [CrossRef] [Scilit]
- Mandic, J.; Sremcev, N.; Piaux, J.; Vrhovac, V.; Kucevic, D.; Stankovski, S. Streamlining Construction Operations: A Holistic Approach with A3 Methodology and Lean Principles. Buildings 2024, 14, 2260. [Google Scholar] [CrossRef] [Scilit]
- Ighravwe, D.E.; Oke, S.A. Sustenance of zero-loss on production lines using Kobetsu Kaizen of TPM with hybrid models. Total Qual. Manag. Bus. Excell. 2020, 31, 112–136. [Google Scholar] [CrossRef] [Scilit]
- Callefi, M.H.; Alves, L.; Thürer, M.; Siegler, J.; Hertel, D. Generative AI in Supply Chain Resource Orchestration: A Conceptual Perspective. IFAC-Pap. 2025, 59, 1480–1485. [Google Scholar] [CrossRef] [Scilit]
- Ghasemibojd, F.; Franchetti, M.J.; George, B. Green lean six sigma for sustainable development: A systematic review of evolution, challenges, and future pathways. Clean Technol. Environ. Policy 2025, 27, 9239–9262. [Google Scholar] [CrossRef] [Scilit]
- Dennison, M.S.; Kumar, M.B.; Jebabalan, S.K. Realization of circular economy principles in manufacturing: Obstacles, advancements, and routes to achieve a sustainable industry transformation. Discov. Sustain. 2024, 5, 438. [Google Scholar] [CrossRef] [Scilit]
- Paladugu, B.S.K.; Grau, D. Toyota Production System–Monitoring Construction Work Progress with Lean Principles. In Encyclopedia of Renewable and Sustainable Materials; Hashmi, S., Choudhury, I.A., Eds.; Elsevier: Oxford, UK, 2020; pp. 560–565. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Hosseinzadeh, A.; Chen, F.F. A Two-Stage Hybrid Federated Learning Framework for Privacy-Preserving IoT Anomaly Detection and Classification. IoT 2025, 6, 48. [Google Scholar] [CrossRef] [Scilit]
- Rossini, M.; Powell, D.J.; Kundu, K. Lean supply chain management and Industry 4.0: A systematic literature review. Int. J. Lean Six Sigma 2022, 14, 253–276. [Google Scholar] [CrossRef] [Scilit]
- Priyadarshini, J.; Singh, R.K.; Mishra, R.; Bag, S. Investigating the interaction of factors for implementing additive manufacturing to build an antifragile supply chain: TISM-MICMAC approach. Oper. Manag. Res. 2022, 15, 567–588. [Google Scholar] [CrossRef] [Scilit]
- Kennon, D.; Schutte, C.S.L.; Lutters, E. An alternative view to assessing antifragility in an organisation: A case study in a manufacturing SME. CIRP Ann. 2015, 64, 177–180. [Google Scholar] [CrossRef] [Scilit]
- Qi, X.; Mei, G. Network Resilience: Definitions, approaches, and applications. J. King Saud Univ.-Comput. Inf. Sci. 2024, 36, 101882. [Google Scholar] [CrossRef] [Scilit]
- Straub, D.; Papaioannou, I.; Betz, W. Bayesian analysis of rare events. J. Comput. Phys. 2016, 314, 538–556. [Google Scholar] [CrossRef] [Scilit]
- Shao, K.; Allen, B.C.; Wheeler, M.W. Bayesian Hierarchical Structure for Quantifying Population Variability to Inform Probabilistic Health Risk Assessments. Risk Anal. Off. Publ. Soc. Risk Anal. 2017, 37, 1865–1878. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Ming, X.; Liang, Q.; Dawson, R.; Xia, X.; Hou, J. A quantitative multi-hazard risk assessment framework for compound flooding considering hazard inter-dependencies and interactions. J. Hydrol. 2022, 607, 127477. [Google Scholar] [CrossRef] [Scilit]
- Hadjigeorgiou, E.; Clark, B.; Simpson, E.; Coles, D.; Comber, R.; Fischer, A.R.H.; Meijer, N.; Marvin, H.J.P.; Frewer, L.J. A systematic review into expert knowledge elicitation methods for emerging food and feed risk identification. Food Control 2022, 136, 108848. [Google Scholar] [CrossRef] [Scilit]
- Jannelli, V.; Schöpf, S.; Bickel, M.; Netland, T.; Brintrup, A. Agentic LLMs in the supply chain: Towards autonomous multi-agent consensus-seeking. Int. J. Prod. Res. 2025, 1–31. [Google Scholar] [CrossRef] [Scilit]
- Valencia-Arias, A.; Rodríguez-Correa, P.A.; Jimenez-Garcia, J.A.; Valencia, J.; Gallegos, A.; Cardona-Acevedo, S.; Benjumea-Arias, M.L. Industrial applications of generative artificial intelligence: Transformations in processes, design, and production. Discov. Artif. Intell. 2025, 5, 327. [Google Scholar] [CrossRef] [Scilit]
- Garcia, C.I.; DiBattista, M.A.; Letelier, T.A.; Halloran, H.D.; Camelio, J.A. Framework for LLM applications in manufacturing. Manuf. Lett. 2024, 41, 253–263. [Google Scholar] [CrossRef] [Scilit]
- Soori, M.; Arezoo, B.; Dastres, R. Digital twin for smart manufacturing, A review. Sustain. Manuf. Serv. Econ. 2023, 2, 100017. [Google Scholar] [CrossRef] [Scilit]
- Mothukuri, V.; Parizi, R.M.; Pouriyeh, S.; Dehghantanha, A.; Choo, K.-K.R. FabricFL: Blockchain-in-the-Loop Federated Learning for Trusted Decentralized Systems. IEEE Syst. J. 2022, 16, 3711–3722. [Google Scholar] [CrossRef] [Scilit]
- Wen, B.; Yao, J.; Feng, S.; Xu, C.; Tsvetkov, Y.; Howe, B.; Wang, L.L. Know Your Limits: A Survey of Abstention in Large Language Models. Trans. Assoc. Comput. Linguist. 2025, 13, 529–556. [Google Scholar] [CrossRef] [Scilit]
- Stengel-Eskin, E.; Van Durme, B. Calibrated Interpretation: Confidence Estimation in Semantic Parsing. Trans. Assoc. Comput. Linguist. 2023, 11, 1213–1231. [Google Scholar] [CrossRef] [Scilit]
- Dey, N.; Ding, J.; Ferrell, J.; Kapper, C.; Lovig, M.; Planchon, E.; Williams, J.P. Conformal Prediction for Text Infilling and Part-of-Speech Prediction. N. Engl. J. Stat. Data Sci. 2023, 1, 69–83. [Google Scholar] [CrossRef] [Scilit]
- Fahland, D. Extracting and pre-processing event logs. arXiv 2022, arXiv:2211.04338. [Google Scholar] [CrossRef] [Scilit]
- Ter Hofstede, A.H.M.; Koschmider, A.; Marrella, A.; Andrews, R.; Fischer, D.A.; Sadeghianasl, S.; Wynn, M.T.; Comuzzi, M.; De Weerdt, J.; Goel, K.; et al. Process-Data Quality: The True Frontier of Process Mining. J. Data Inf. Qual. 2023, 15, 1–21. [Google Scholar] [CrossRef] [Scilit]
- Fischer, D.A.; Goel, K.; Andrews, R.; van Dun, C.G.J.; Wynn, M.T.; Röglinger, M. Enhancing Event Log Quality: Detecting and Quantifying Timestamp Imperfections. In Proceedings of the Business Process Management: 18th International Conference, BPM 2020, Seville, Spain, 13–18 September 2020; Springer: Berlin/Heidelberg, Germany, 2020; pp. 309–326. [Google Scholar] [CrossRef] [Scilit]
- Denisov, V.; Fahland, D.; van der Aalst, W.M.P. Repairing Event Logs with Missing Events to Support Performance Analysis of Systems with Shared Resources. Appl. Theory Petri Nets Concurr. 2020, 12152, 239–259. [Google Scholar] [CrossRef] [Scilit]
- Marin-Castro, H.M.; Tello-Leal, E. Event Log Preprocessing for Process Mining: A Review. Appl. Sci. 2021, 11, 10556. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Chen, F.F.; Maghanaki, M.; Mehrzadi, H.; Hosseinzadeh, A. Toward sustainable production: A synthetic dataset framework to accelerate quality control via generative and predictive AI. Int. J. Adv. Manuf. Technol. 2025, 138, 5979–6018. [Google Scholar] [CrossRef] [Scilit]
- Kirchherr, J.; Yang, N.-H.N.; Schulze-Spüntrup, F.; Heerink, M.J.; Hartley, K. Conceptualizing the Circular Economy (Revisited): An Analysis of 221 Definitions. Resour. Conserv. Recycl. 2023, 194, 107001. [Google Scholar] [CrossRef] [Scilit]
- Hernandez Marquina, M.V.; Zwolinski, P.; Mangione, F. Application of Value Stream Mapping tool to improve circular systems. Clean. Eng. Technol. 2021, 5, 100270. [Google Scholar] [CrossRef] [Scilit]
- Muñoz, S.; Hosseini, M.R.; Crawford, R.H. Towards a holistic assessment of circular economy strategies: The 9R circularity index. Sustain. Prod. Consum. 2024, 47, 400–412. [Google Scholar] [CrossRef] [Scilit]
- Nascimento, D.L.M.; Alencastro, V.; Quelhas, O.L.G.; Caiado, R.G.G.; Garza-Reyes, J.A.; Rocha-Lona, L.; Tortorella, G. Exploring Industry 4.0 technologies to enable circular economy practices in a manufacturing context: A business model proposal. J. Manuf. Technol. Manag. 2019, 30, 607–627. [Google Scholar] [CrossRef] [Scilit]
- Luo, Y.; Madarkar, R.; Luo, X.; Ball, P. Leveraging Digital Twins and Dynamic Life Cycle Assessment for Sustainable Manufacturing: A Conceptual Framework. In Decarbonizing Value Chains. GCSM 2024; Kohl, H., Seliger, G., Dietrich, F., Vien, H.T., Eds.; Lecture Notes in Mechanical Engineering; Springer: Cham, Switzerland, 2025. [Google Scholar] [CrossRef] [Scilit]
- Mariani, F.; Ciommi, M. Aggregating Composite Indicators through the Geometric Mean: A Penalization Approach. Computation 2022, 10, 64. [Google Scholar] [CrossRef] [Scilit]
- Tofallis, C. On constructing a composite indicator with multiplicative aggregation and the avoidance of zero weights in DEA. J. Oper. Res. Soc. 2014, 65, 791–792. [Google Scholar] [CrossRef] [Scilit]
- Ferreira, D.C.; Caldas, P.; Varela, M.; Marques, R.C. A geometric aggregation of performance indicators considering regulatory constraints: An application to the urban solid waste management. Expert Syst. Appl. 2023, 218, 119540. [Google Scholar] [CrossRef] [Scilit]
- Su, S.; Ju, J.; Ding, Y.; Yuan, J.; Cui, P. A Comprehensive Dynamic Life Cycle Assessment Model: Considering Temporally and Spatially Dependent Variations. Int. J. Environ. Res. Public Health 2022, 19, 14000. [Google Scholar] [CrossRef] [Scilit]
- Weber, C.L.; Jaramillo, P.; Marriott, J.; Samaras, C. Life Cycle Assessment and Grid Electricity: What Do We Know and What Can We Know? Environ. Sci. Technol. 2010, 44, 1895–1901. [Google Scholar] [CrossRef] [Scilit]
- Liu, X.; Cui, Q. Baseline manipulation in voluntary carbon offset programs. Energy Policy 2017, 111, 9–17. [Google Scholar] [CrossRef] [Scilit]
- Huertos, F.J.; Masenlle, M.; Chicote, B.; Ayuso, M. Hyperconnected Architecture for High Cognitive Production Plants. Procedia CIRP 2021, 104, 1692–1697. [Google Scholar] [CrossRef] [Scilit]
- Madsen, D.Ø.; Berg, T.; Slåtten, K. Four Futures of Industry 6.0: Scenario-Based Speculation Beyond Human-Centric Production; Social Science Research Network: Rochester, NY, USA, 2025; p. 5354848. [Google Scholar] [CrossRef] [Scilit]
- Pan, J.J.; Bell, M.G.H.; Cheung, K.F.; Perera, S.; Yu, H. Connectivity analysis of the global shipping network by eigenvalue decomposition. Marit. Policy Manag. 2019, 46, 957–966. [Google Scholar] [CrossRef] [Scilit]
- Nizamis, A.; Gkonis, P.; Ioannidis, D.; Ntafalias, A.; Tzovaras, D.; Trakadas, P. Manufacturing data spaces applications in europe-A survey. Data Brief 2025, 63, 112149. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Jorzik, N.; Kirchhof, P.J.; Mueller-Langer, F. Industrial data sharing and data readiness: A law and economics perspective. Eur. J. Law Econ. 2024, 57, 181–205. [Google Scholar] [CrossRef] [Scilit]
- Pan, J.-J.; Zhang, Y.-F.; Fan, B. Strengthening container shipping network connectivity during COVID-19: A graph theory approach. Ocean Coast. Manag. 2022, 229, 106338. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Lyu, Z.; Fridenfalk, M. Digital twins for building industrial metaverse. J. Adv. Res. 2023, 66, 31–38. [Google Scholar] [CrossRef] [Scilit]
- Hazra, A.; Adhikari, M.; Amgoth, T.; Srirama, S.N. A Comprehensive Survey on Interoperability for IIoT: Taxonomy, Standards, and Future Directions. ACM Comput. Surv. 2021, 55, 1–35. [Google Scholar] [CrossRef] [Scilit]
- Fiedler, M. Algebraic connectivity of graphs. Czechoslov. Math. J. 1973, 23, 298–305. [Google Scholar] [CrossRef] [Scilit]
- Golub, G.H.; Zhang, Z.; Zha, H. Large sparse symmetric eigenvalue problems with homogeneous linear constraints: The Lanczos process with inner–outer iterations. Linear Algebra Its Appl. 2000, 309, 289–306. [Google Scholar] [CrossRef] [Scilit]
- Spielman, D.A.; Teng, S.-H. Spectral Sparsification of Graphs. SIAM J. Comput. 2011, 40, 981–1025. [Google Scholar] [CrossRef] [Scilit]
- Gebeyehu, S.G.; Abebe, M.; Gochel, A. Production lead time improvement through lean manufacturing. Cogent Eng. 2022, 9, 2034255. [Google Scholar] [CrossRef] [Scilit]
- Ng Corrales, L.d.C.; Lambán, M.P.; Hernandez Korner, M.E.; Royo, J. Overall Equipment Effectiveness: Systematic Literature Review and Overview of Different Approaches. Appl. Sci. 2020, 10, 6469. [Google Scholar] [CrossRef] [Scilit]
- Schmitt, T.; Hoffmann, M.; Rodemann, T.; Adamy, J. Incorporating Human Preferences in Decision Making for Dynamic Multi-Objective Optimization in Model Predictive Control. Inventions 2022, 7, 46. [Google Scholar] [CrossRef] [Scilit]
- Berti, A.; van Zelst, S.; Schuster, D. PM4Py: A process mining library for Python. Softw. Impacts 2023, 17, 100556. [Google Scholar] [CrossRef] [Scilit]
- Pedregosa, F.; Varoquaux, G.; Gramfort, A.; Michel, V.; Thirion, B.; Grisel, O.; Blondel, M.; Prettenhofer, P.; Weiss, R.; Dubourg, V.; et al. Scikit-learn: Machine Learning in Python. J. Mach. Learn. Res. 2011, 12, 2825–2830. [Google Scholar] [CrossRef]
- Paszke, A.; Gross, S.; Massa, F.; Lerer, A.; Bradbury, J.; Chanan, G.; Killeen, T.; Lin, Z.; Gimelshein, N.; Antiga, L.; et al. PyTorch: An imperative style, high-performance deep learning library. In Proceedings of the 33rd International Conference on Neural Information Processing Systems, Vancouver, BC, Canada, 8–14 December 2019; Curran Associates Inc.: Red Hook, NY, USA, 2019; pp. 8026–8037. [Google Scholar] [CrossRef]
- Shahin, M.; Chen, F.F.; Hosseinzadeh, A. Harnessing customized AI to create voice of customer via GPT3.5. Adv. Eng. Inform. 2024, 61, 102462. [Google Scholar] [CrossRef] [Scilit]
- Shahin, M.; Chen, F.F.; Hosseinzadeh, A.; Maghanaki, M.; Eghbalian, A. A novel approach to voice of customer extraction using GPT-3.5 Turbo: Linking advanced NLP and Lean Six Sigma 4.0. Int. J. Adv. Manuf. Technol. 2024, 131, 3615–3630. [Google Scholar] [CrossRef] [Scilit]
- Campos, M.; Farinhas, A.; Zerva, C.; Figueiredo, M.A.T.; Martins, A.F.T. Conformal Prediction for Natural Language Processing: A Survey. Trans. Assoc. Comput. Linguist. 2024, 12, 1497–1516. [Google Scholar] [CrossRef] [Scilit]
- Ciroth, A. ICT for environment in life cycle applications openLCA—A new open source software for life cycle assessment. Int. J. Life Cycle Assess. 2007, 12, 209–210. [Google Scholar] [CrossRef]
- Millette, S.; Williams, E.; Hull, C.E. Materials flow analysis in support of circular economy development: Plastics in Trinidad and Tobago. Resour. Conserv. Recycl. 2019, 150, 104436. [Google Scholar] [CrossRef] [Scilit]
- Mutel, C. Brightway: An open source framework for Life Cycle Assessment. J. Open Source Softw. 2017, 2, 236. [Google Scholar] [CrossRef] [Scilit]
- Maghanaki, M.; Keramati, S.; Chen, F.F.; Shahin, M. Generation of a Multi-Class IoT Malware Dataset for Cybersecurity. Electronics 2025, 14, 4196. [Google Scholar] [CrossRef] [Scilit]
- Saltelli, A. Making best use of model evaluations to compute sensitivity indices. Comput. Phys. Commun. 2002, 145, 280–297. [Google Scholar] [CrossRef] [Scilit]
- Marino, S.; Hogue, I.B.; Ray, C.J.; Kirschner, D.E. A Methodology for Performing Global Uncertainty and Sensitivity Analysis in Systems Biology. J. Theor. Biol. 2008, 254, 178–196. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Saltelli, A. Sensitivity analysis: Could better methods be used? J. Geophys. Res. Atmos. 1999, 104, 3789–3793. [Google Scholar] [CrossRef] [Scilit]
- Sobol, I.M. Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates. Math. Comput. Simul. 2001, 55, 271–280. [Google Scholar] [CrossRef] [Scilit]
- Siler, K.; Larivière, V. Who games metrics and rankings? Institutional niches and journal impact factor inflation. Res. Policy 2022, 51, 104608. [Google Scholar] [CrossRef] [Scilit]
- Holmstrom, B.; Milgrom, P. Multitask Principal–Agent Analyses: Incentive Contracts, Asset Ownership, and Job Design. J. Law Econ. Organ. 1991, 7, 24–52. [Google Scholar] [CrossRef] [Scilit]
- Manheim, D. Building less-flawed metrics: Understanding and creating better measurement and incentive systems. Patterns 2023, 4, 100842. [Google Scholar] [CrossRef] [Scilit]
- Bevan, G.; Hood, C. What’s Measured Is What Matters: Targets and Gaming in the English Public Health Care System. Public Adm. 2006, 84, 517–538. [Google Scholar] [CrossRef] [Scilit]
- Akidau, T.; Begoli, E.; Chernyak, S.; Hueske, F.; Knight, K.; Knowles, K.; Mills, D.; Sotolongo, D. Watermarks in stream processing systems: Semantics and comparative analysis of Apache Flink and Google cloud dataflow. Proc. VLDB Endow. 2021, 14, 3135–3147. [Google Scholar] [CrossRef] [Scilit]
- Tahir, J.; Mayer, R.; Doblander, C.; Jacobsen, H.-A. How Reliable are Streams? End-to-End Processing-Guarantee Validation and Performance Benchmarking of Stream Processing Systems. Proc. VLDB Endow. 2024, 18, 585–598. [Google Scholar] [CrossRef] [Scilit]
- Luo, H.; Hu, Z. Stability analysis of sampled-data control systems with multiple time-varying delays. J. Frankl. Inst. 2020, 357, 6615–6634. [Google Scholar] [CrossRef] [Scilit]
- Ames, A.D.; Coogan, S.; Egerstedt, M.; Notomista, G.; Sreenath, K.; Tabuada, P. Control Barrier Functions: Theory and Applications. In Proceedings of the 2019 18th European Control Conference (ECC), Naples, Italy, 25–28 June 2019; pp. 3420–3431. [Google Scholar] [CrossRef] [Scilit]
- Schwarm, A.T.; Nikolaou, M. Chance-constrained model predictive control. AIChE J. 1999, 45, 1743–1752. [Google Scholar] [CrossRef] [Scilit]
- Goddard, K.; Roudsari, A.; Wyatt, J.C. Automation bias: A systematic review of frequency, effect mediators, and mitigators. J. Am. Med. Inform. Assoc. JAMIA 2012, 19, 121–127. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Gomersall, T. Complex adaptive systems: A new approach for understanding health practices. Health Psychol. Rev. 2018, 12, 405–418. [Google Scholar] [CrossRef] [Scilit] [PubMed]
- Ahmad, M.A.; Baryannis, G.; Hill, R. Defining Complex Adaptive Systems: An Algorithmic Approach. Systems 2024, 12, 45. [Google Scholar] [CrossRef] [Scilit]
- Notarnicola, I.; Lommi, M.; Ivziku, D.; Carrodano, S.; Rocco, G.; Stievano, A. The Nursing Theory of Complex Adaptive Systems: A New Paradigm for Nursing. Healthcare 2024, 12, 1997. [Google Scholar] [CrossRef] [Scilit]
- Zhang, X.; Nutakor, F.; Minlah, M.K.; Li, J. Can Digital Transformation Drive Green Transformation in Manufacturing Companies?—Based on Socio-Technical Systems Theory Perspective. Sustainability 2023, 15, 2840. [Google Scholar] [CrossRef] [Scilit]
- Govers, M.; van Amelsvoort, P. A theoretical essay on socio-technical systems design thinking in the era of digital transformation. Gr. Interakt. Organ. Z. Angew. Organ. GIO 2023, 54, 27–40. [Google Scholar] [CrossRef] [Scilit]
- Carayon, P.; Bass, E.J.; Bellandi, T.; Gurses, A.P.; Hallbeck, M.S.; Mollo, V. Sociotechnical systems analysis in health care: A research agenda. IIE Trans. Healthc. Syst. Eng. 2011, 1, 145–160. [Google Scholar] [CrossRef] [Scilit]
- Binder, C.R.; Athanassiadis, A.; Bristow, D.; Haberl, H.; Kennedy, C. Tipping points toward sustainability: The role of industrial ecology. J. Ind. Ecol. 2025, 29, 622–633. [Google Scholar] [CrossRef] [Scilit]
- Gong, Y.; Ma, F.; Wang, H.; Tzachor, A.; Sun, W.; Zhu, J.; Liu, G.; Schandl, H. The evolution of research at the intersection of industrial ecology and artificial intelligence. J. Ind. Ecol. 2025, 29, 440–457. [Google Scholar] [CrossRef] [Scilit]
- Corbier, D.; Pettifor, H.; Agnew, M.; Drouet, L. CIRCEE, the CIRCular Energy Economy model: Bridging the gap between economic and industrial ecology concepts. J. Ind. Ecol. 2024, 28, 1996–2011. [Google Scholar] [CrossRef] [Scilit]
- da Silva Stefano, G.; Pacheco Lacerda, D.; Isabel Wolf Motta Morandi, M.; Augusto Cassel, R.; Denicol, J. How important is the Theory of Constraints to supply chain management? An assessment of its application and impacts. Comput. Ind. Eng. 2024, 198, 110717. [Google Scholar] [CrossRef] [Scilit]
- Ukey, K.; Chinta, L.; Majumder, H.; Patil, D.S.; Mitkari, S.; Sahu, A.R.; Dhutekar, P.K. Implementation of the Theory of Constraints (TOC) for a Furniture Manufacturing-Based Organization. Eng. Proc. 2025, 114, 17. [Google Scholar] [CrossRef] [Scilit]
- Gupta, M.; Digalwar, A.; Gupta, A.; Goyal, A. Integrating Theory of Constraints, Lean and Six Sigma: A framework development and its application. Prod. Plan. Control 2024, 35, 238–261. [Google Scholar] [CrossRef] [Scilit]




























| Dimension | I4.0/I5.0 (Current) | I6.0 (Emerging) | Key References |
|---|---|---|---|
| Intelligence Model | Human-in-the-loop AI, assisting human decisions | Generative AI autonomy, co-creating and executing workflows | [1,6] |
| Operational Paradigm | Efficiency and robustness | Antifragility and adaptability | [9,20] |
| Sustainability Model | Standalone “green” initiatives, minimizing negative impact | Integrated circular economy, regenerative by design | [10,20] |
| System Boundary | The smart factory and its immediate supply chain | The hyper-connected virtual–physical ecosystem | [1,18] |
| Driving Technology | IoT, Cloud, Big Data, Cobots | Generative AI, Quantum Computing, 6G, IoX, Digital Twins | [1,10,20,21] |
| Human Role | Operator, collaborator, decision-maker | Strategic intent provider, ethicist, ecosystem designer | [21,22] |
| Scenario | Phase | AFI | GOE | CIS | ECI |
|---|---|---|---|---|---|
| Demand shock | Baseline | −0.010 | 9.414 | 0.502 | 0.656 |
| Demand shock | Disruption | 0.004 | 2.479 | 0.479 | 0.614 |
| Demand shock | Recovery | 0.004 | 8.970 | 0.515 | 0.662 |
| Supplier failure | Baseline | −0.008 | 9.712 | 0.501 | 0.656 |
| Supplier failure | Disruption | −0.052 | 1.700 | 0.503 | 0.588 |
| Supplier failure | Recovery | −0.040 | 0.526 | 0.514 | 0.664 |
| Cyber incident | Baseline | 0.003 | 9.434 | 0.501 | 0.656 |
| Cyber incident | Disruption | −0.025 | 1.216 | 0.483 | 0.354 |
| Cyber incident | Recovery | 0.012 | 6.109 | 0.518 | 0.662 |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Shahin, M.; Maghanaki, M.; Chen, F.F. Integration of Lean Analytics and Industry 6.0: A Novel Meta-Theoretical Framework for Antifragile, Generative AI-Orchestrated, Circular–Regenerative, and Hyper-Connected Manufacturing Ecosystems. Big Data Cogn. Comput. 2026, 10, 65. https://doi.org/10.3390/bdcc10020065
Shahin M, Maghanaki M, Chen FF. Integration of Lean Analytics and Industry 6.0: A Novel Meta-Theoretical Framework for Antifragile, Generative AI-Orchestrated, Circular–Regenerative, and Hyper-Connected Manufacturing Ecosystems. Big Data and Cognitive Computing. 2026; 10(2):65. https://doi.org/10.3390/bdcc10020065
Chicago/Turabian StyleShahin, Mohammad, Mazdak Maghanaki, and F. Frank Chen. 2026. "Integration of Lean Analytics and Industry 6.0: A Novel Meta-Theoretical Framework for Antifragile, Generative AI-Orchestrated, Circular–Regenerative, and Hyper-Connected Manufacturing Ecosystems" Big Data and Cognitive Computing 10, no. 2: 65. https://doi.org/10.3390/bdcc10020065
APA StyleShahin, M., Maghanaki, M., & Chen, F. F. (2026). Integration of Lean Analytics and Industry 6.0: A Novel Meta-Theoretical Framework for Antifragile, Generative AI-Orchestrated, Circular–Regenerative, and Hyper-Connected Manufacturing Ecosystems. Big Data and Cognitive Computing, 10(2), 65. https://doi.org/10.3390/bdcc10020065

